Autoimmune inflammation from the Th17 perspective

Autoimmunity Reviews

Volumn 6, Issue 3, 2007, Pages 169-175

  Furuzawa Carballeda, Janette ^a   Vargas Rojas, María Inés ^a   Cabral, Antonio R ^a  

^a INSTITUTO NACIONAL DE CIENCIAS MÉDICAS Y NUTRICIÓN SALVADOR ZUBIRÁN   (Mexico)

Author keywords

IL 17; IL 23; Rheumatoid arthritis; Th1 Th2 Th17 lineages

Indexed keywords

CELL NUCLEUS RECEPTOR; GAMMA INTERFERON; GAMMA INTERFERON ANTIBODY; INTERLEUKIN 1; INTERLEUKIN 12; INTERLEUKIN 23; INTERLEUKIN 27; INTERLEUKIN 6; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA;

ALLERGIC ENCEPHALOMYELITIS; ANTIGEN SPECIFICITY; CD4+ T LYMPHOCYTE; CELL DIFFERENTIATION; CELL LINEAGE; CORRELATION ANALYSIS; DISEASE RESISTANCE; EFFECTOR CELL; GENE TARGETING; HELPER CELL; HELPER CELL TYPE 17; KNOCKOUT MOUSE; MULTIPLE SCLEROSIS; NONHUMAN; REVIEW; RHEUMATOID ARTHRITIS; TARGET ORGAN; TH1 CELL; TH2 CELL;

ANIMALS; ARTHRITIS, EXPERIMENTAL; ARTHRITIS, RHEUMATOID; AUTOIMMUNE DISEASES; CELL DIFFERENTIATION; CELL LINEAGE; GENE TARGETING; HUMANS; INTERLEUKIN-17; INTERLEUKIN-23; MICE; MICE, KNOCKOUT; MODELS, IMMUNOLOGICAL; RECEPTORS, RETINOIC ACID; RECEPTORS, THYROID HORMONE; T-LYMPHOCYTES, HELPER-INDUCER;

EID: 33846608583     PISSN: 15689972     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.autrev.2006.10.002     Document Type: Review

References (40)

1. Harrington L.E., Mangan P.R., and Weaver CT. Expanding the effector CD4 T-cell repertoire: the Th17 lineage. Curr Opin Immunol 18 (2006) 349-356
2. Mosmann T.R., and Sad S. The expanding universe of T-cell subsets: Th1, Th2 and more. Immunol Today 17 3 (1996) 138-146
3. Manoury-Schwartz B., Chiocchia G., Bessis N., Abehsira-Amar O., Batteux F., Muller S., et al. High susceptibility to collagen-induced arthritis in mice lacking IFN-γ receptors. J Immunol 158 (1997) 5504-5506
4. Vermeire K., Heremans H., Vandeputte M., Huang S., Billiau A., and Maththys P. Accelerated collagen-induced arthritis in IFNγ receptor-deficient mice. J Immunol 158 (1997) 5507-5513
5. Kageyama Y., Koide Y., Yoshida A., Uchijima M., Arai T., Miyamoto S., et al. Reduced susceptibility to collagen-induced arthritis in mice deficient in IFN-gamma receptor. J Immunol 161 (1998) 1542-1548
6. Bettelli E., Sullivan B., Szabo S.J., Sobel R.A., Glimcher L.H., and Kuchroo V.K. Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis. J Exp Med 200 (2004) 79-87
7. Heremans H., Dillien C., Groenen M., Martens E., and Billiau A. Chronic relapsing experimental autoimmune encephalomyelitis (CREAE) in mice: enhancement by monoclonal antibodies against interferon-γ. Eur J Immunol 26 (1996) 2393-2398
8. Farber A., Brocke S., Taylor-Edwards C., Ridgway W., Dinisco C., Steinman L., et al. Mice with a disrupted IFN-gamma gene are susceptible to the induction of experimental autoimmune encephalomyelitis (EAE). J Immunol 156 (1996) 5-7
9. Willenborg D.O., Fordham S., Bernard C., Cowden W.B., and Ramshaw I.A. IFN-gamma plays a critical down-regulatory role in the induction and effector phase of myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis. J Immunol 157 (1996) 3223-3227
10. Infante-Duarte C., Horton H.F., Byrne M.C., and Kamradt T. Microbial lipopetides induce the production of IL-17 in Th cells. J Immunol 165 (2000) 6107-6115
11. Aggarwal S., Ghilardi N., Xie M.H., de Sauvage F.J., and Gurney A.L. Interleukin-23 promotes a distinct CD 4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 278 (2003) 1910-1914
12. Langrish C.L., Chen Y., Blumenschein W.M., Mattson J., Basham B., Sedgwick J.D., et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 201 (2005) 233-240
13. Cua D.J., Sherlock J., Chen Y.I., Murphy C.A., Joyce B., Seymour B., et al. Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature 421 (2003) 744-748
14. Murphy C.A., Langrish C.L., Chen Y., Blumenschein W.M., McClanahan T., Kastelein R.A., et al. Divergent pro- and antiinflammatory roles for IL-23 and IL-12 in joint autoimmune inflammation. J Exp Med 198 (2003) 1951-1957
15. Lubberts E., Koenders M.I., and van der Berg W. The role of T cell interleukin-17 in conducting destructive arthritis: lessons from animal models. Arthritis Res Ther 7 (2005) 29-37
16. Harrington L.E., Hatton R.D., Managan P.R., Turner H., Murphy T.L., Murphy K.M., et al. Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6 (2005) 1123-1132
17. Park H., Li Z., Yang X.O., Chang S.H., Nurieva R., Wang Y.H., et al. A distinct lineage of CD4 T cells regulate tissue inflammation by producing interleukin 17. Nat Immunol 6 11 (2005) 1133-1141
18. Mangan P.R., Harrington L.E., Quinn D.B., Helms W.S., Bullard D.C., Elson C.O., et al. Transforming growth factor-β induces development of the TH17 lineage. Nature 441 (2006) 231-234
19. Veldhoen M., Hocking R.J., Atkins C.J., Locksley R.M., and Stockinger B. TGFβ in the context of an inflammatory cytokine mieliu supports de novo differentiation of IL-17 producing T cells. Immunity 24 (2006) 179-189
20. + regulatory T cells by TGF-β induction of transcription factor Foxp3. J Exp Med 198 (2003) 1875-1886
21. Betteli E., Carrier Y., Gao W., Korn T., Strom T.B., Oukka M., et al. Reciprocal developmental pathways for the generation of pathogenic effects TH17 regulatory T cells. Nature 441 (2006) 235-238
22. Sutton C., Brereton C., Keogh B., Mills K.H.G., and Lavelle E.C. A crucial role for interleukin (IL)-1 in the induction of IL-17-producing T cells that mediate autoimmune encephalomyelitis. J Exp Med 203 (2006) 1685-1691
23. Batten M., Li J., Yi S., Kljavin N.M., Danilenko D.M., Lucas S., et al. Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat Rev Immunol 7 9 (2006) 929-936
24. Stumhofer J.S., Laurence A., Wilson E.H., Huang E., Tato C.M., Johnson L.M., et al. Interleukin 27 negatively regulates the development of interleukin 17-producing T helper cells during chronic inflammation of the central nervous system. Nat Immunol 7 9 (2006) 937-945
25. + T helper cells. Cell 126 (2006) 1121-1133
26. Schen Z., Laurance A., Kanno Y., Pacher-Zavisin M., Bing-Mei Z., Tato C., et al. Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. PNAS 103 (2006) 8137-8142
27. Kolls J.K., and Linden A. Interleukin-17 family members and inflammation. Immunity 21 (2004) 467-476
28. Beadling C., and Slifka M.K. Regulation of innate and adaptative immune responses by the related cytokines IL-12, IL-23, and IL-27. Arch Immunol Ther Exp 54 (2006) 1-10
29. Kotake S., Udagawa N., Takahashi N., Matsuzaki K., Itoh K., IIshiyama S., et al. IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J Clin Invest 103 (1999) 1345-1352
30. Cho M.L., Yoon C.H., Hwang S.Y., Park M.K., Min Y.S., Lee S.H., et al. Effector function of type II collagen-stimulated T cells from rheumatoid arthritis patients. Cross-talk between T cells and synovial fibroblasts. Arthritis Rheum 50 (2004) 776-784
31. Kim H.R., Cho M.L., Kim K.W., Juhn J.Y., Hwang S.Y., Yoon C.H., et al. Up-regulation of IL-23p19 expression in rheumatoid arthritis synovial fibroblasts by IL-17 through PI3-kinase-NF-κ-B and p38 MAPK-dependent signaling pathways. Rheumatology (2006) 10.1093/rheumatology/kel159
32. Hwang S.Y., and Kim H.Y. Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients. Mol Cell 19 (2004) 180-184
33. Honorati M.C., Meliconi R., Pulsatelli L., Canè S., Frizziero L., and Facchini A. High in vivo expression of interleukin-17 receptor in synovial endothelial cells and chondrocytes from arthritis patients. Rheumatology 40 (2001) 522-527
34. Aarvak T., Chabaud M., Miossec P., and Natvig J. IL-17 is produced by some proinflammatory Th1/Th0 cells but not by Th2 cells. J Immunol 162 (1999) 1246-1251
35. Hwang S.Y., Kim J.Y., Park M.K., Moon Y., Kim W.U., and Kim H.Y. IL-17 induces production of IL-6 and IL-8 in rheumatoid arthritis synovial fibroblasts via NF-κB- and P13-kinase/AK1-dependent pathways. Arthritis Res Ther 6 (2004) 120-128
36. Ryu S., Lee J.H., and Kim S.I. IL-17 increased the production of vascular endothelial growth factor in rheumatoid arthritis synoviocytes. Clin Rheumatol 25 (2005) 16-20
37. Chabaud M., Lubberts E., Joosten L., van der Berg W., and Miossec P. IL-17 derived from juxta-articular and synovium contributes to joint degradation in rheumatoid arthritis. Arthritis Res 3 (2001) 168-177
38. van Bezooijen R.L., van der Wee-Pals L., Papapoulos S.E., and Löwik C.W.G.M. Interleukin 17 synergises with tumor necrosis factor α to induce cartilage destruction in vitro. Ann Rheum Dis 61 (2002) 870-876
39. Raza K., Falaciani F., Curnow S.J., Ross E.J., Lee C.-Y., Akbar A.N., et al. Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin. Arthritis Res Ther 7 (2005) R784-R795
40. Kirkham B.W., Lassere M.N., Edmonds J.P., Juhasz K.M., Bird P.A., Lee C.S., et al. Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis. A two-year prospective study (the DAMAGE study cohort). Arthritis Rheum 54 (2006) 1122-1131