Nuclear factor-κB translocation mediates double-stranded ribonucleic acid-induced NIT-1 β-cell apoptosis and up-regulates caspase-12 and tumor necrosis factor receptor-associated ligand (TRAIL)

Endocrinology

Volumn 144, Issue 10, 2003, Pages 4616-4625

  Robbins, Marjorie A ^a,b   Maksumova, Lola ^b   Pocock, Emma ^b   Chantler, Janet K ^a,b  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^b CHILDREN S AND WOMEN S HEALTH CENTRE OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE; CASPASE 12; CASPASE 3; CASPASE 8; DOUBLE STRANDED RNA; FAS ANTIGEN; I KAPPA B; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 15; POLYINOSINIC POLYCYTIDYLIC ACID; SN 50; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; UNCLASSIFIED DRUG; APOPTOSIS REGULATORY PROTEIN; CASPASE 9; ENZYME INHIBITOR; INITIATION FACTOR 2; LIPID; LIPOFECTAMINE; MEMBRANE PROTEIN; NF KAPPAB INHIBITOR ALPHA; NF-KAPPAB INHIBITOR ALPHA; NITRIC OXIDE; PROTEIN KINASE R; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE TRANSLOCATION; GENETIC TRANSFECTION; MOUSE; NICK END LABELING; NONHUMAN; PANCREAS ISLET BETA CELL; PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN FUNCTION; STATISTICAL SIGNIFICANCE; UPREGULATION; ANIMAL; BIOSYNTHESIS; CELL LINE; CELL NUCLEUS; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; PANCREAS ISLET; PHYSIOLOGY; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALS; ANTIGENS, CD95; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BIOLOGICAL TRANSPORT; CASPASE 12; CASPASE 3; CASPASE 8; CASPASE 9; CASPASES; CELL LINE; CELL NUCLEUS; EIF-2 KINASE; ENZYME INHIBITORS; EUKARYOTIC INITIATION FACTOR-2; I-KAPPA B PROTEINS; INTERLEUKIN-15; ISLETS OF LANGERHANS; LIPIDS; MEMBRANE GLYCOPROTEINS; NF-KAPPA B; NITRIC OXIDE; POLY I-C; RNA, DOUBLE-STRANDED; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0141562049     PISSN: 00137227     EISSN: None     Source Type: Journal    
DOI: 10.1210/en.2003-0266     Document Type: Article

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