Phosphoinositide 3-kinaseγ controls the intracellular localization of CpG to limit dna-pkcs-dependent il-10 production in macrophages

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Hazeki, Kaoru ^a   Kametani, Yukiko ^a   Murakami, Hiroki ^a   Uehara, Masami ^a   Ishikawa, Yuki ^a   Nigorikawa, Kiyomi ^a   Takasuga, Shunsuke ^b   Sasaki, Takehiko ^b   Seya, Tsukasa ^c   Matsumoto, Misako ^c   Hazeki, Osamu ^a  

^a HIROSHIMA UNIVERSITY   (Japan)

^b AKITA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^c HOKKAIDO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

5 [5 (4 FLUORO 2 HYDROXYPHENYL)FURFURYLIDENE] 2,4 THIAZOLIDINEDIONE; CPG OLIGODEOXYNUCLEOTIDE; DNA DEPENDENT PROTEIN KINASE; DNA DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT; EARLY ENDOSOME ANTIGEN 1; INTERLEUKIN 10; LIPOPOLYSACCHARIDE; PHOSPHATIDYLINOSITOL 3 KINASE GAMMA; PHOSPHATIDYLINOSITOL 3 KINASE P100 GAMMA; UNCLASSIFIED DRUG; WORTMANNIN; ACID; ANDROSTANE DERIVATIVE; CATION; CPG OLIGONUCLEOTIDE; CPG-OLIGONUCLEOTIDE; LIPOSOME; OLIGODEOXYRIBONUCLEOTIDE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PIK3CG PROTEIN, MOUSE;

ACIDIFICATION; ANIMAL CELL; ARTICLE; BINDING SITE; CELL MIGRATION; CELL STIMULATION; CELL STRAIN COS7; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENDOSOME; ENZYME ACTIVITY; ENZYME INDUCTION; INNATE IMMUNITY; LYSOSOME; MACROPHAGE; MOUSE; MUTANT; NONHUMAN; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; WILD TYPE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DRUG EFFECT; ENZYMOLOGY; FEMALE; INTRACELLULAR SPACE; METABOLISM; MOUSE MUTANT; PROTEIN TRANSPORT;

MUS;

ACIDS; ANDROSTADIENES; ANIMALS; CATIONS; CLASS IB PHOSPHATIDYLINOSITOL 3-KINASE; DNA-ACTIVATED PROTEIN KINASE; ENDOSOMES; FEMALE; INTERLEUKIN-10; INTRACELLULAR SPACE; LIPOPOLYSACCHARIDES; LIPOSOMES; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, SCID; OLIGODEOXYRIBONUCLEOTIDES; PROTEIN TRANSPORT;

EID: 80055032878     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0026836     Document Type: Article

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