-
1
-
-
58049106258
-
-
Accessed July-12th-2011
-
WHO Fact sheet: Obesity and overweight. http://www.who.int/ dietphysicalactivity/publications/facts/obesity/en/ (Accessed July-12th-2011)
-
WHO Fact Sheet: Obesity and Overweight
-
-
-
2
-
-
79959936188
-
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: Systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants
-
10.1016/S0140-6736(11)60679-X
-
National, regional, and global trends in fasting plasma glucose and diabetes prevalence since 1980: systematic analysis of health examination surveys and epidemiological studies with 370 country-years and 2.7 million participants. Danaei G, Finucane MM, Lu Y, Singh GM, Cowan MJ, Paciorek CJ, Lin JK, Farzadfar F, Khang Y-H, Stevens GA, et al. The Lancet 2011 378 9785 31 40 10.1016/S0140-6736(11)60679-X
-
(2011)
The Lancet
, vol.378
, Issue.9785
, pp. 31-40
-
-
Danaei, G.1
Finucane, M.M.2
Lu, Y.3
Singh, G.M.4
Cowan, M.J.5
Paciorek, C.J.6
Lin, J.K.7
Farzadfar, F.8
Khang, Y.-H.9
Stevens, G.A.10
-
3
-
-
51849146897
-
Global burden of obesity in 2005 and projections to 2030
-
10.1038/ijo.2008.102
-
Global burden of obesity in 2005 and projections to 2030. Kelly T, Yang W, Chen CS, Reynolds K, He J, Int J Obes 2008 32 9 1431 1437 10.1038/ijo.2008.102
-
(2008)
Int J Obes
, vol.32
, Issue.9
, pp. 1431-1437
-
-
Kelly, T.1
Yang, W.2
Chen, C.S.3
Reynolds, K.4
He, J.5
-
4
-
-
0028931724
-
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance
-
10.1172/JCI117936 7738205
-
Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance. Hotamisligil GS, Arner P, Caro JF, Atkinson RL, Spiegelman BM, J Clin Invest 1995 95 5 2409 2415 10.1172/JCI117936 7738205
-
(1995)
J Clin Invest
, vol.95
, Issue.5
, pp. 2409-2415
-
-
Hotamisligil, G.S.1
Arner, P.2
Caro, J.F.3
Atkinson, R.L.4
Spiegelman, B.M.5
-
5
-
-
0027459878
-
Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
-
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Hotamisligil GS, Shargill NS, Spiegelman BM, Science 1993 259 5091 87 91 10.1126/science.7678183 7678183 (Pubitemid 23036092)
-
(1993)
Science
, vol.259
, Issue.5091
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
6
-
-
51349156218
-
Insulin sensitivity: Modulation by nutrients and inflammation
-
10.1172/JCI34260 18769626
-
Insulin sensitivity: modulation by nutrients and inflammation. Schenk S, Saberi M, Olefsky JM, J Clin Invest 2008 118 9 2992 3002 10.1172/JCI34260 18769626
-
(2008)
J Clin Invest
, vol.118
, Issue.9
, pp. 2992-3002
-
-
Schenk, S.1
Saberi, M.2
Olefsky, J.M.3
-
7
-
-
62849107511
-
Markers of inflammation and hemodynamic measurements in obesity: Copenhagen City Heart Study
-
10.1038/ajh.2009.1 19229196
-
Markers of inflammation and hemodynamic measurements in obesity: Copenhagen City Heart Study. Asferg C, Jensen JS, Marott JL, Appleyard M, Mogelvang R, Jensen GB, Jeppesen J, Am J Hypertens 2009 22 4 451 456 10.1038/ajh.2009.1 19229196
-
(2009)
Am J Hypertens
, vol.22
, Issue.4
, pp. 451-456
-
-
Asferg, C.1
Jensen, J.S.2
Marott, J.L.3
Appleyard, M.4
Mogelvang, R.5
Jensen, G.B.6
Jeppesen, J.7
-
8
-
-
36048982779
-
Inflammation, obesity and comorbidities: The role of diet
-
DOI 10.1017/S1368980007000663, PII S1368980007000663
-
Inflammation, obesity and comorbidities: the role of diet. Bullo M, Casas-Agustench P, Amigo-Correig P, Aranceta J, Salas-Salvado J, Public Health Nutr 2007 10 10A 1164 1172 17903326 (Pubitemid 350085205)
-
(2007)
Public Health Nutrition
, vol.10
, Issue.10 A
, pp. 1164-1172
-
-
Bullo, M.1
Casas-Agustench, P.2
Amigo-Correig, P.3
Aranceta, J.4
Salas-Salvado, J.5
-
9
-
-
70049110648
-
Inflammation, adipokines and obesity
-
10.1016/j.revmed.2009.03.363 19394723
-
[Inflammation, adipokines and obesity]. Clement K, Vignes S, Rev Med Interne 2009 30 9 824 832 10.1016/j.revmed.2009.03.363 19394723
-
(2009)
Rev Med Interne
, vol.30
, Issue.9
, pp. 824-832
-
-
Clement, K.1
Vignes, S.2
-
10
-
-
34548639473
-
Obesity-induced inflammation: A metabolic dialogue in the language of inflammation
-
DOI 10.1111/j.1365-2796.2007.01852.x
-
Obesity-induced inflammation: a metabolic dialogue in the language of inflammation. Ferrante AW Jr, J Intern Med 2007 262 4 408 414 10.1111/j.1365-2796.2007.01852.x 17875176 (Pubitemid 47404372)
-
(2007)
Journal of Internal Medicine
, vol.262
, Issue.4
, pp. 408-414
-
-
Ferrante Jr., A.W.1
-
11
-
-
33644856005
-
Obesity and the role of adipose tissue in inflammation and metabolism
-
Obesity and the role of adipose tissue in inflammation and metabolism. Greenberg AS, Obin MS, Am J Clin Nutr 2006 83 2 461S 465S 16470013 (Pubitemid 44713219)
-
(2006)
American Journal of Clinical Nutrition
, vol.83
, Issue.2
-
-
Greenberg, A.S.1
Obin, M.S.2
-
12
-
-
58149484392
-
Inflammation and endoplasmic reticulum stress in obesity and diabetes
-
Inflammation and endoplasmic reticulum stress in obesity and diabetes. Hotamisligil GS, Int J Obes (Lond) 2008 32 Suppl 7 52 54
-
(2008)
Int J Obes (Lond)
, Issue.32 SUPPL 7
, pp. 1952-54
-
-
Hotamisligil, G.S.1
-
13
-
-
79251491895
-
Obesity and inflammation: III
-
17883979
-
Obesity and inflammation: III. Hurt RT, Frazier TH, Matheson PJ, Cave MC, Garrison RN, McClain CJ, McClave SA, Curr Gastroenterol Rep 2007 9 4 307 308 17883979
-
(2007)
Curr Gastroenterol Rep
, vol.9
, Issue.4
, pp. 307-308
-
-
Hurt, R.T.1
Frazier, T.H.2
Matheson, P.J.3
Cave, M.C.4
Garrison, R.N.5
McClain, C.J.6
McClave, S.A.7
-
14
-
-
79251490565
-
Obesity and inflammation: II
-
17883978
-
Obesity and inflammation: II. Hurt RT, Frazier TH, Matheson PJ, Cave MC, Garrison RN, McClain CJ, McClave SA, Curr Gastroenterol Rep 2007 9 4 306 307 17883978
-
(2007)
Curr Gastroenterol Rep
, vol.9
, Issue.4
, pp. 306-307
-
-
Hurt, R.T.1
Frazier, T.H.2
Matheson, P.J.3
Cave, M.C.4
Garrison, R.N.5
McClain, C.J.6
McClave, S.A.7
-
15
-
-
78751649211
-
Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity
-
10.1016/j.soard.2010.05.013 20678967
-
Body mass index-independent inflammation in omental adipose tissue associated with insulin resistance in morbid obesity. Hardy OT, Perugini RA, Nicoloro SM, Gallagher-Dorval K, Puri V, Straubhaar J, Czech MP, Surgery for Obesity and Related Diseases 2011 7 1 60 67 10.1016/j.soard.2010.05.013 20678967
-
(2011)
Surgery for Obesity and Related Diseases
, vol.7
, Issue.1
, pp. 60-67
-
-
Hardy, O.T.1
Perugini, R.A.2
Nicoloro, S.M.3
Gallagher-Dorval, K.4
Puri, V.5
Straubhaar, J.6
Czech, M.P.7
-
16
-
-
9144223683
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance
-
DOI 10.1172/JCI200319451
-
Chronic inflammation in fat plays a crucial role in the development of obesity-related insulin resistance. Xu H, Barnes GT, Yang Q, Tan G, Yang D, Chou CJ, Sole J, Nichols A, Ross JS, Tartaglia LA, et al. J Clin Invest 2003 112 12 1821 1830 14679177 (Pubitemid 38063705)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1821-1830
-
-
Xu, H.1
Barnes, G.T.2
Yang, Q.3
Tan, G.4
Yang, D.5
Chou, C.J.6
Sole, J.7
Nichols, A.8
Ross, J.S.9
Tartaglia, L.A.10
Chen, H.11
-
18
-
-
0348230958
-
Obesity is associated with macrophage accumulation in adipose tissue
-
DOI 10.1172/JCI200319246
-
Obesity is associated with macrophage accumulation in adipose tissue. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr, J Clin Invest 2003 112 12 1796 1808 14679176 (Pubitemid 38063703)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1796-1808
-
-
Weisberg, S.P.1
McCann, D.2
Desai, M.3
Rosenbaum, M.4
Leibel, R.L.5
Ferrante Jr., A.W.6
-
19
-
-
70349277011
-
Chronic mild inflammation links obesity, metabolic syndrome, atherosclerosis and diabetes
-
19731872
-
[Chronic mild inflammation links obesity, metabolic syndrome, atherosclerosis and diabetes]. Andel M, Polak J, Kraml P, Dlouhy P, Stich V, Vnitr Lek 2009 55 7-8 659 665 19731872
-
(2009)
Vnitr Lek
, vol.55
, Issue.7-8
, pp. 659-665
-
-
Andel, M.1
Polak, J.2
Kraml, P.3
Dlouhy, P.4
Stich, V.5
-
20
-
-
36849005372
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via toll-like receptors 2 and 4 and JNK-dependent pathways
-
DOI 10.1074/jbc.M706762200
-
A subpopulation of macrophages infiltrates hypertrophic adipose tissue and is activated by free fatty acids via Toll-like receptors 2 and 4 and JNK-dependent pathways. Nguyen MT, Favelyukis S, Nguyen AK, Reichart D, Scott PA, Jenn A, Liu-Bryan R, Glass CK, Neels JG, Olefsky JM, J Biol Chem 2007 282 48 35279 35292 10.1074/jbc.M706762200 17916553 (Pubitemid 350232441)
-
(2007)
Journal of Biological Chemistry
, vol.282
, Issue.48
, pp. 35279-35292
-
-
Nguyen, M.T.A.1
Favelyukis, S.2
Nguyen, A.-K.3
Reichart, D.4
Scott, P.A.5
Jenn, A.6
Liu-Bryan, R.7
Glass, C.K.8
Neels, J.G.9
Olefsky, J.M.10
-
21
-
-
33748755008
-
Toll-like receptor-2 is essential for the development of palmitate-induced insulin resistance in myotubes
-
DOI 10.1074/jbc.M513304200
-
Toll-like Receptor-2 Is Essential for the Development of Palmitate-induced Insulin Resistance in Myotubes. Senn JJ, Journal of Biological Chemistry 2006 281 37 26865 26875 10.1074/jbc.M513304200 16798732 (Pubitemid 44401715)
-
(2006)
Journal of Biological Chemistry
, vol.281
, Issue.37
, pp. 26865-26875
-
-
Senn, J.J.1
-
22
-
-
33750584214
-
TLR4 links innate immunity and fatty acid-induced insulin resistance
-
DOI 10.1172/JCI28898
-
TLR4 links innate immunity and fatty acid induced insulin resistance. Shi H, Kokoeva MV, Inouye K, Tzameli I, Yin H, Flier JS, The Journal of Clinical Investigation 2006 116 11 3015 3025 10.1172/JCI28898 17053832 (Pubitemid 44684486)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.11
, pp. 3015-3025
-
-
Shi, H.1
Kokoeva, M.V.2
Inouye, K.3
Tzameli, I.4
Yin, H.5
Flier, J.S.6
-
23
-
-
0012929728
-
Toll-like receptors
-
DOI 10.1146/annurev.immunol.21.120601.141126
-
Toll-like receptors. Takeda K, Kaisho T, Akira S, Annual Review of Immunology 2003 21 1 335 376 10.1146/annurev.immunol.21.120601.141126 12524386 (Pubitemid 37174535)
-
(2003)
Annual Review of Immunology
, vol.21
, pp. 335-376
-
-
Takeda, K.1
Kaisho, T.2
Akira, S.3
-
24
-
-
78649817454
-
NOD2 activation induces muscle cell-autonomous innate immune responses and insulin resistance
-
10.1210/en.2010-0437 20926588
-
NOD2 activation induces muscle cell-autonomous innate immune responses and insulin resistance. Tamrakar AK, Schertzer JD, Chiu TT, Foley KP, Bilan PJ, Philpott DJ, Klip A, Endocrinology 2010 151 12 5624 5637 10.1210/en.2010-0437 20926588
-
(2010)
Endocrinology
, vol.151
, Issue.12
, pp. 5624-5637
-
-
Tamrakar, A.K.1
Schertzer, J.D.2
Chiu, T.T.3
Foley, K.P.4
Bilan, P.J.5
Philpott, D.J.6
Klip, A.7
-
25
-
-
39749084162
-
Proinflammatory cytokines in obesity: Impact of type 2 diabetes mellitus and gastric bypass
-
10.1007/s11695-008-9424-z 18219773
-
Proinflammatory cytokines in obesity: impact of type 2 diabetes mellitus and gastric bypass. Catalan V, Gomez-Ambrosi J, Ramirez B, Rotellar F, Pastor C, Silva C, Rodriguez A, Gil MJ, Cienfuegos JA, Fruhbeck G, Obes Surg 2007 17 11 1464 1474 10.1007/s11695-008-9424-z 18219773
-
(2007)
Obes Surg
, vol.17
, Issue.11
, pp. 1464-1474
-
-
Catalan, V.1
Gomez-Ambrosi, J.2
Ramirez, B.3
Rotellar, F.4
Pastor, C.5
Silva, C.6
Rodriguez, A.7
Gil, M.J.8
Cienfuegos, J.A.9
Fruhbeck, G.10
-
26
-
-
0031471921
-
Role of pro- and anti-inflammatory cytokines during inflammation: Experimental and clinical findings
-
Role of pro- and anti-inflammatory cytokines during inflammation: experimental and clinical findings. Dinarello CA, J Biol Regul Homeost Agents 1997 11 3 91 103 9498158 (Pubitemid 28045963)
-
(1997)
Journal of Biological Regulators and Homeostatic Agents
, vol.11
, Issue.3
, pp. 91-103
-
-
Dinarello, C.A.1
-
27
-
-
33846194125
-
Innate immunity - cross-talk with adaptive immunity through pattern recognition receptors and cytokines
-
DOI 10.1016/j.coi.2006.11.018, PII S0952791506002500, Innate immunity/Antigen processing and recognition
-
Innate immunity - cross-talk with adaptive immunity through pattern recognition receptors and cytokines. Kabelitz D, Medzhitov R, Curr Opin Immunol 2007 19 1 1 3 10.1016/j.coi.2006.11.018 17157490 (Pubitemid 46091738)
-
(2007)
Current Opinion in Immunology
, vol.19
, Issue.1
, pp. 1-3
-
-
Kabelitz, D.1
Medzhitov, R.2
-
28
-
-
0348010591
-
Importance of adipocytokines in obesity-related diseases
-
DOI 10.1159/000074502
-
Importance of adipocytokines in obesity-related diseases. Matsuzawa Y, Shimomura I, Kihara S, Funahashi T, Horm Res 2003 60 Suppl 3 56 59 14671398 (Pubitemid 37548205)
-
(2003)
Hormone Research
, vol.60
, Issue.SUPPL. 3
, pp. 56-59
-
-
Matsuzawa, Y.1
Shimomura, I.2
Kihara, S.3
Funahashi, T.4
-
29
-
-
77249132284
-
Adipose tissue inflammation in obesity and metabolic syndrome
-
19788868
-
Adipose tissue inflammation in obesity and metabolic syndrome. Nishimura S, Manabe I, Nagai R, Discov Med 2009 8 41 55 60 19788868
-
(2009)
Discov Med
, vol.8
, Issue.41
, pp. 55-60
-
-
Nishimura, S.1
Manabe, I.2
Nagai, R.3
-
30
-
-
33645888426
-
Monocyte chemotactic protein-1 is a potential player in the negative cross-talk between adipose tissue and skeletal muscle
-
10.1210/en.2005-0969 16439461
-
Monocyte chemotactic protein-1 is a potential player in the negative cross-talk between adipose tissue and skeletal muscle. Sell H, Dietze-Schroeder D, Kaiser U, Eckel J, Endocrinology 2006 147 5 2458 2467 10.1210/en.2005-0969 16439461
-
(2006)
Endocrinology
, vol.147
, Issue.5
, pp. 2458-2467
-
-
Sell, H.1
Dietze-Schroeder, D.2
Kaiser, U.3
Eckel, J.4
-
31
-
-
0033779714
-
Free fatty acids and pathogenesis of type 2 diabetes mellitus
-
10.1016/S1043-2760(00)00323-4 11042464
-
Free Fatty Acids and Pathogenesis of Type 2 Diabetes Mellitus. Bergman RN, Ader M, Trends in Endocrinology and Metabolism 2000 11 9 351 356 10.1016/S1043-2760(00)00323-4 11042464
-
(2000)
Trends in Endocrinology and Metabolism
, vol.11
, Issue.9
, pp. 351-356
-
-
Bergman, R.N.1
Ader, M.2
-
32
-
-
42949116365
-
Lipid accumulation in non-adipose tissue and lipotoxicity
-
DOI 10.1016/j.physbeh.2007.11.049, PII S0031938407004805
-
Lipid accumulation in non-adipose tissue and lipotoxicity. van Herpen NA, Schrauwen-Hinderling VB, Physiol Behav 2008 94 2 231 241 10.1016/j.physbeh. 2007.11.049 18222498 (Pubitemid 351615422)
-
(2008)
Physiology and Behavior
, vol.94
, Issue.2
, pp. 231-241
-
-
Van Herpen, N.A.1
Schrauwen-Hinderling, V.B.2
-
33
-
-
63849125553
-
Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice
-
19204053
-
Examination of 'lipotoxicity' in skeletal muscle of high-fat fed and ob/ob mice. Turpin SM, Ryall JG, Southgate R, Darby I, Hevener AL, Febbraio MA, Kemp BE, Lynch GS, Watt MJ, J Physiol 2009 587 Pt 7 1593 1605 19204053
-
(2009)
J Physiol
, vol.587
, Issue.PART 7
, pp. 1593-1605
-
-
Turpin, S.M.1
Ryall, J.G.2
Southgate, R.3
Darby, I.4
Hevener, A.L.5
Febbraio, M.A.6
Kemp, B.E.7
Lynch, G.S.8
Watt, M.J.9
-
34
-
-
77949330439
-
Chemotactic cytokines, obesity and type 2 diabetes: In vivo and in vitro evidence for a possible causal correlation?
-
10.1017/S0029665109990218 19698204
-
Chemotactic cytokines, obesity and type 2 diabetes: in vivo and in vitro evidence for a possible causal correlation? Sell H, Eckel J, Proc Nutr Soc 2009 68 4 378 384 10.1017/S0029665109990218 19698204
-
(2009)
Proc Nutr Soc
, vol.68
, Issue.4
, pp. 378-384
-
-
Sell, H.1
Eckel, J.2
-
35
-
-
70349484212
-
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
-
10.1016/j.cmet.2009.08.013 19808018
-
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Kleinridders A, Schenten D, Konner AC, Belgardt BF, Mauer J, Okamura T, Wunderlich FT, Medzhitov R, Bruning JC, Cell Metab 2009 10 4 249 259 10.1016/j.cmet.2009.08.013 19808018
-
(2009)
Cell Metab
, vol.10
, Issue.4
, pp. 249-259
-
-
Kleinridders, A.1
Schenten, D.2
Konner, A.C.3
Belgardt, B.F.4
Mauer, J.5
Okamura, T.6
Wunderlich, F.T.7
Medzhitov, R.8
Bruning, J.C.9
-
36
-
-
51049095934
-
Diet-induced inflammation of the hypothalamus in obesity
-
10.1159/000153423 18781083
-
Diet-induced inflammation of the hypothalamus in obesity. Velloso LA, Araujo EP, de Souza CT, Neuroimmunomodulation 2008 15 3 189 193 10.1159/000153423 18781083
-
(2008)
Neuroimmunomodulation
, vol.15
, Issue.3
, pp. 189-193
-
-
Velloso, L.A.1
Araujo, E.P.2
De Souza, C.T.3
-
37
-
-
70349478989
-
Does hypothalamic inflammation cause obesity?
-
10.1016/j.cmet.2009.09.003 19808014
-
Does hypothalamic inflammation cause obesity? Wisse BE, Schwartz MW, Cell Metab 2009 10 4 241 242 10.1016/j.cmet.2009.09.003 19808014
-
(2009)
Cell Metab
, vol.10
, Issue.4
, pp. 241-242
-
-
Wisse, B.E.1
Schwartz, M.W.2
-
38
-
-
80054871627
-
Conditioned medium from hypoxia-treated adipocytes renders muscle cells insulin resistant
-
10.1016/j.ejcb.2011.06.004 21962636
-
Conditioned medium from hypoxia-treated adipocytes renders muscle cells insulin resistant. Yu J, Shi L, Wang H, Bilan PJ, Yao Z, Samaan MC, He Q, Klip A, Niu W, Eur J Cell Biol 2011 90 12 1000 1015 10.1016/j.ejcb.2011.06.004 21962636
-
(2011)
Eur J Cell Biol
, vol.90
, Issue.12
, pp. 1000-1015
-
-
Yu, J.1
Shi, L.2
Wang, H.3
Bilan, P.J.4
Yao, Z.5
Samaan, M.C.6
He, Q.7
Klip, A.8
Niu, W.9
-
39
-
-
57349137607
-
HIF-1alpha protein rather than mRNA as a marker of hypoxia in adipose tissue in obesity: Focus on "inflammation is associated with a decrease of lipogenic factors in omental fat in women," by Poulain-Godefroy et al
-
author reply R1098 10.1152/ajpregu.90633.2008 18832093
-
HIF-1alpha protein rather than mRNA as a marker of hypoxia in adipose tissue in obesity: focus on "inflammation is associated with a decrease of lipogenic factors in omental fat in women," by Poulain-Godefroy et al. Trayhurn P, Wang B, Wood IS, Am J Physiol Regul Integr Comp Physiol 2008 295 4 1097 author reply R1098 10.1152/ajpregu.90633.2008 18832093
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
, Issue.4
, pp. 181097
-
-
Trayhurn, P.1
Wang, B.2
Wood, I.S.3
-
40
-
-
58149500277
-
Emerging role of adipose tissue hypoxia in obesity and insulin resistance
-
10.1038/ijo.2008.229
-
Emerging Role of Adipose Tissue Hypoxia in Obesity and Insulin Resistance. Ye J, Int J Obes (Lond) 2009 33 1 54 66 10.1038/ijo.2008.229
-
(2009)
Int J Obes (Lond)
, vol.33
, Issue.1
, pp. 54-66
-
-
Ye, J.1
-
41
-
-
34547569051
-
Obesity, inflammation, and vascular disease: The role of the adipose tissue as an endocrine organ
-
10.1007/1-4020-5688-53-17612046
-
Obesity, inflammation, and vascular disease: the role of the adipose tissue as an endocrine organ. Calabro P, Yeh ET, Subcell Biochem 2007 42 63 91 10.1007/1-4020-5688-53-17612046
-
(2007)
Subcell Biochem
, vol.42
, pp. 63-91
-
-
Calabro, P.1
Yeh, E.T.2
-
42
-
-
0036958112
-
Adipose tissue gene expression in patients with a loss of function mutation in the leptin receptor
-
DOI 10.1038/sj.ijo.0802180
-
Adipose tissue gene expression in patients with a loss of function mutation in the leptin receptor. Clement K, Vega N, Laville M, Pelloux V, Guy-Grand B, Basdevant A, Vidal H, Int J Obes Relat Metab Disord 2002 26 12 1533 1538 10.1038/sj.ijo.0802180 12461669 (Pubitemid 36099000)
-
(2002)
International Journal of Obesity
, vol.26
, Issue.12
, pp. 1533-1538
-
-
Clement, K.1
Vega, N.2
Laville, M.3
Pelloux, V.4
Guy-Grand, B.5
Basdevant, A.6
Vidal, H.7
-
43
-
-
0033575993
-
Effects of recombinant leptin therapy in a child with congenital leptin deficiency
-
DOI 10.1056/NEJM199909163411204
-
Effects of recombinant leptin therapy in a child with congenital leptin deficiency. Farooqi IS, Jebb SA, Langmack G, Lawrence E, Cheetham CH, Prentice AM, Hughes IA, McCamish MA, O'Rahilly S, N Engl J Med 1999 341 12 879 884 10.1056/NEJM199909163411204 10486419 (Pubitemid 29427050)
-
(1999)
New England Journal of Medicine
, vol.341
, Issue.12
, pp. 879-884
-
-
Farooqi, I.S.1
Jebb, S.A.2
Langmack, G.3
Lawrence, E.4
Cheetham, C.H.5
Prentice, A.M.6
Hughes, I.A.7
McCamish, M.A.8
O'Rahilly, S.9
-
44
-
-
61449105725
-
Leptin: A pivotal regulator of human energy homeostasis
-
10.3945/ajcn.2008.26788C 19211814
-
Leptin: a pivotal regulator of human energy homeostasis. Farooqi IS, O'Rahilly S, Am J Clin Nutr 2009 89 3 980S 984S 10.3945/ajcn.2008.26788C 19211814
-
(2009)
Am J Clin Nutr
, vol.89
, Issue.3
-
-
Farooqi, I.S.1
O'Rahilly, S.2
-
45
-
-
35649010345
-
Adiponectin, resistin and subclinical inflammation - The metabolic burden in Launois Bensaude Syndrome, a rare form of obesity
-
Adiponectin, resistin and subclinical inflammation - the metabolic burden in Launois Bensaude Syndrome, a rare form of obesity. Harsch IA, Bergmann T, Koebnick C, Wiedmann R, Ruderich F, Hahn EG, Konturek PC, J Physiol Pharmacol 2007 58 Suppl 1 65 76 (Pubitemid 350022259)
-
(2007)
Journal of Physiology and Pharmacology
, vol.58
, Issue.SUPPL. 1
, pp. 65-76
-
-
Harsch, I.A.1
Bergmann, T.2
Koebnick, C.3
Wiedmann, R.4
Ruderich, F.5
Hahn, E.G.6
Konturek, P.C.7
-
46
-
-
0842308729
-
Unraveling the multiple roles of leptin in inflammation and autoimmunity
-
DOI 10.1007/s00109-003-0492-1
-
Unraveling the multiple roles of leptin in inflammation and autoimmunity. La Cava A, Alviggi C, Matarese G, J Mol Med 2004 82 1 4 11 10.1007/s00109-003- 0492-1 14556053 (Pubitemid 38168097)
-
(2004)
Journal of Molecular Medicine
, vol.82
, Issue.1
, pp. 4-11
-
-
La Cava, A.1
Alviggi, C.2
Matarese, G.3
-
47
-
-
52949129178
-
Leptin resistance: A possible interface of inflammation and metabolism in obesity-related cardiovascular disease
-
10.1016/j.jacc.2008.05.060 18926322
-
Leptin resistance: a possible interface of inflammation and metabolism in obesity-related cardiovascular disease. Martin SS, Qasim A, Reilly MP, J Am Coll Cardiol 2008 52 15 1201 1210 10.1016/j.jacc.2008.05.060 18926322
-
(2008)
J Am Coll Cardiol
, vol.52
, Issue.15
, pp. 1201-1210
-
-
Martin, S.S.1
Qasim, A.2
Reilly, M.P.3
-
48
-
-
9144244927
-
Resistin and type 2 diabetes: Regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes
-
DOI 10.1210/jc.2003-030898
-
Resistin and type 2 diabetes: regulation of resistin expression by insulin and rosiglitazone and the effects of recombinant resistin on lipid and glucose metabolism in human differentiated adipocytes. McTernan PG, Fisher FM, Valsamakis G, Chetty R, Harte A, McTernan CL, Clark PM, Smith SA, Barnett AH, Kumar S, J Clin Endocrinol Metab 2003 88 12 6098 6106 10.1210/jc.2003-030898 14671216 (Pubitemid 38033098)
-
(2003)
Journal of Clinical Endocrinology and Metabolism
, vol.88
, Issue.12
, pp. 6098-6106
-
-
McTernan, P.G.1
Fisher, F.M.2
Valsamakis, G.3
Chetty, R.4
Harte, A.5
McTernan, C.L.6
Clark, P.M.S.7
Smith, S.A.8
Barnett, A.H.9
Kumar, S.10
-
49
-
-
6944237757
-
Adipokines: Inflammation and the pleiotropic role of white adipose tissue
-
DOI 10.1079/BJN20041213
-
Adipokines: inflammation and the pleiotropic role of white adipose tissue. Trayhurn P, Wood IS, Br J Nutr 2004 92 3 347 355 10.1079/BJN20041213 15469638 (Pubitemid 40277057)
-
(2004)
British Journal of Nutrition
, vol.92
, Issue.3
, pp. 347-355
-
-
Trayhurn, P.1
Wood, I.S.2
-
50
-
-
27844545767
-
Signalling role of adipose tissue: Adipokines and inflammation in obesity
-
DOI 10.1042/BST20051078
-
Signalling role of adipose tissue: adipokines and inflammation in obesity. Trayhurn P, Wood IS, Biochem Soc Trans 2005 33 Pt 5 1078 1081 16246049 (Pubitemid 41659117)
-
(2005)
Biochemical Society Transactions
, vol.33
, Issue.5
, pp. 1078-1081
-
-
Trayhurn, P.1
Wood, I.S.2
-
51
-
-
53149119231
-
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding
-
10.1194/jlr.M800132-JLR200 18503031
-
Neutrophils transiently infiltrate intra-abdominal fat early in the course of high-fat feeding. Elgazar-Carmon V, Rudich A, Hadad N, Levy R, J Lipid Res 2008 49 9 1894 1903 10.1194/jlr.M800132-JLR200 18503031
-
(2008)
J Lipid Res
, vol.49
, Issue.9
, pp. 1894-1903
-
-
Elgazar-Carmon, V.1
Rudich, A.2
Hadad, N.3
Levy, R.4
-
52
-
-
20644449495
-
Monocytes and macrophages - Multifaced cell population involved in inflammation, atherosclerosis, and obesity
-
15861644
-
[Monocytes and macrophages - multifaced cell population involved in inflammation, atherosclerosis, and obesity]. Takeya M, Nippon Rinsho 2005 63 Suppl 4 117 122 15861644
-
(2005)
Nippon Rinsho
, vol.63
, Issue.SUPPL 4
, pp. 117-122
-
-
Takeya, M.1
-
53
-
-
11244329029
-
Skeletal muscle lipid accumulation in obesity, insulin resistance, and type 2 diabetes
-
DOI 10.1111/j.1399-543X.2004.00071.x
-
Skeletal muscle lipid accumulation in obesity, insulin resistance, and type 2 diabetes. Goodpaster BH, Wolf D, Pediatr Diabetes 2004 5 4 219 226 10.1111/j.1399-543X.2004.00071.x 15601366 (Pubitemid 40057693)
-
(2004)
Pediatric Diabetes
, vol.5
, Issue.4
, pp. 219-226
-
-
Goodpaster, B.H.1
Wolf, D.2
-
54
-
-
0346880505
-
Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance
-
14704745
-
Inflammation and the IKK beta/I kappa B/NF-kappa B axis in obesity- and diet-induced insulin resistance. Shoelson SE, Lee J, Yuan M, Int J Obes Relat Metab Disord 2003 27 Suppl 3 49 52 14704745
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
, Issue.SUPPL 3
, pp. 1949-52
-
-
Shoelson, S.E.1
Lee, J.2
Yuan, M.3
-
56
-
-
0346880502
-
Molecular mechanisms of inflammation in obesity-linked insulin resistance
-
14704744
-
Molecular mechanisms of inflammation in obesity-linked insulin resistance. Marette A, Int J Obes Relat Metab Disord 2003 27 Suppl 3 46 48 14704744
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
, Issue.SUPPL 3
, pp. 1946-48
-
-
Marette, A.1
-
57
-
-
0346880504
-
Inflammatory pathways and insulin action
-
14704746
-
Inflammatory pathways and insulin action. Hotamisligil GS, Int J Obes Relat Metab Disord 2003 27 Suppl 3 53 55 14704746
-
(2003)
Int J Obes Relat Metab Disord
, vol.27
, Issue.SUPPL 3
, pp. 1953-55
-
-
Hotamisligil, G.S.1
-
58
-
-
77953110535
-
Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice
-
Induction of regulatory T cells decreases adipose inflammation and alleviates insulin resistance in ob/ob mice. Ilan Y, Maron R, Tukpah AM, Maioli TU, Murugaiyan G, Yang K, Wu HY, Weiner HL, Proc Natl Acad Sci USA 107 21 9765 9770
-
Proc Natl Acad Sci USA
, vol.107
, Issue.21
, pp. 9765-9770
-
-
Ilan, Y.1
Maron, R.2
Tukpah, A.M.3
Maioli, T.U.4
Murugaiyan, G.5
Yang, K.6
Wu, H.Y.7
Weiner, H.L.8
-
59
-
-
68349127290
-
T-ing up inflammation in fat
-
10.1038/nm0809-846 19661987
-
T-ing up inflammation in fat. Lumeng CN, Maillard I, Saltiel AR, Nat Med 2009 15 8 846 847 10.1038/nm0809-846 19661987
-
(2009)
Nat Med
, vol.15
, Issue.8
, pp. 846-847
-
-
Lumeng, C.N.1
Maillard, I.2
Saltiel, A.R.3
-
60
-
-
46249117032
-
T-lymphocyte infiltration in visceral adipose tissue: A primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance
-
10.1161/ATVBAHA.108.165100 18420999
-
T-lymphocyte infiltration in visceral adipose tissue: a primary event in adipose tissue inflammation and the development of obesity-mediated insulin resistance. Kintscher U, Hartge M, Hess K, Foryst-Ludwig A, Clemenz M, Wabitsch M, Fischer-Posovszky P, Barth TF, Dragun D, Skurk T, et al. Arterioscler Thromb Vasc Biol 2008 28 7 1304 1310 10.1161/ATVBAHA.108.165100 18420999
-
(2008)
Arterioscler Thromb Vasc Biol
, vol.28
, Issue.7
, pp. 1304-1310
-
-
Kintscher, U.1
Hartge, M.2
Hess, K.3
Foryst-Ludwig, A.4
Clemenz, M.5
Wabitsch, M.6
Fischer-Posovszky, P.7
Barth, T.F.8
Dragun, D.9
Skurk, T.10
-
61
-
-
25844456730
-
Tumor necrosis factor-α induces skeletal muscle insulin resistance in healthy human subjects via inhibition of Akt substrate 160 phosphorylation
-
DOI 10.2337/diabetes.54.10.2939
-
Tumor Necrosis Factor- Induces Skeletal Muscle Insulin Resistance in Healthy Human Subjects via Inhibition of Akt Substrate 160 Phosphorylation. Plomgaard P, Bouzakri K, Krogh-Madsen R, Mittendorfer B, Zierath JR, Pedersen BK, Diabetes 2005 54 10 2939 2945 10.2337/diabetes.54.10.2939 16186396 (Pubitemid 41401090)
-
(2005)
Diabetes
, vol.54
, Issue.10
, pp. 2939-2945
-
-
Plomgaard, P.1
Bouzakri, K.2
Krogh-Madsen, R.3
Mittendorfer, B.4
Zierath, J.R.5
Pedersen, B.K.6
-
62
-
-
0030685825
-
IKK-1 and IKK-2: Cytokine-activated IκB kinases essential for NF-κB activation
-
DOI 10.1126/science.278.5339.860
-
IKK-1 and IKK-2: Cytokine-Activated IkB Kinases Essential for NF-kB Activation. Mercurio F, Zhu H, Murray BW, Shevchenko A, Bennett BL, Li Jw, Young DB, Barbosa M, Mann M, Manning A, et al. Science 1997 278 5339 860 866 10.1126/science.278.5339.860 9346484 (Pubitemid 27467923)
-
(1997)
Science
, vol.278
, Issue.5339
, pp. 860-866
-
-
Mercurio, F.1
Zhu, H.2
Murray, B.W.3
Shevchenko, A.4
Bennett, B.L.5
Li, J.W.6
Young, D.B.7
Barbosa, M.8
Mann, M.9
Manning, A.10
Rao, A.11
-
63
-
-
0032487857
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of IκB kinase-β
-
DOI 10.1038/23948
-
The anti-inflammatory agents aspirin and salicylate inhibit the activity of I(kappa)B kinase-beta. Yin MJ, Yamamoto Y, Gaynor RB, Nature 1998 396 6706 77 80 10.1038/23948 9817203 (Pubitemid 28520452)
-
(1998)
Nature
, vol.396
, Issue.6706
, pp. 77-80
-
-
Yin, M.-J.1
Yamamoto, Y.2
Gaynor, R.B.3
-
64
-
-
20044387026
-
IKK-β links inflammation to obesity-induced insulin resistance
-
DOI 10.1038/nm1185
-
IKK-beta links inflammation to obesity-induced insulin resistance. Arkan MC, Hevener AL, Greten FR, Maeda S, Li ZW, Long JM, Wynshaw-Boris A, Poli G, Olefsky J, Karin M, Nat Med 2005 11 2 191 198 10.1038/nm1185 15685170 (Pubitemid 40321355)
-
(2005)
Nature Medicine
, vol.11
, Issue.2
, pp. 191-198
-
-
Arkan, M.C.1
Hevener, A.L.2
Greten, F.R.3
Maeda, S.4
Li, Z.-W.5
Long, J.M.6
Wynshaw-Boris, A.7
Poli, G.8
Olefsky, J.9
Karin, M.10
-
65
-
-
52349105273
-
A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity
-
18773087
-
A predominant role for parenchymal c-Jun amino terminal kinase (JNK) in the regulation of systemic insulin sensitivity. Vallerie SN, Furuhashi M, Fucho R, Hotamisligil GS, PLoS One 2008 3 9 3151. 18773087
-
(2008)
PLoS One
, vol.3
, Issue.9
, pp. 53151
-
-
Vallerie, S.N.1
Furuhashi, M.2
Fucho, R.3
Hotamisligil, G.S.4
-
66
-
-
0037153158
-
A central, role for JNK in obesity and insulin resistance
-
DOI 10.1038/nature01137
-
A central role for JNK in obesity and insulin resistance. Hirosumi J, Tuncman G, Chang L, Gorgun CZ, Uysal KT, Maeda K, Karin M, Hotamisligil GS, Nature 2002 420 6913 333 336 10.1038/nature01137 12447443 (Pubitemid 35398190)
-
(2002)
Nature
, vol.420
, Issue.6913
, pp. 333-336
-
-
Hirosumi, J.1
Tuncman, G.2
Chang, L.3
Gorgun, C.Z.4
Uysal, K.T.5
Maeda, K.6
Karin, M.7
Hotamisligil, G.S.8
-
67
-
-
0034708832
-
307
-
DOI 10.1074/jbc.275.12.9047
-
The c-Jun NH(2)-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser(307). Aguirre V, Uchida T, Yenush L, Davis R, White MF, J Biol Chem 2000 275 12 9047 9054 10.1074/jbc.275.12.9047 10722755 (Pubitemid 30180265)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.12
, pp. 9047-9054
-
-
Aguirre, V.1
Uchida, T.2
Yenush, L.3
Davis, R.4
White, M.F.5
-
68
-
-
77955806634
-
JNK1 and IKK: Molecular links between obesity and metabolic dysfunction
-
JNK1 and IKK: molecular links between obesity and metabolic dysfunction. Solinas G, Karin M, The FASEB Journal 24 8 2596 2611
-
The FASEB Journal
, vol.24
, Issue.8
, pp. 2596-2611
-
-
Solinas, G.1
Karin, M.2
-
69
-
-
33644750396
-
Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes
-
16306344
-
Role of endoplasmic reticulum stress and c-Jun NH2-terminal kinase pathways in inflammation and origin of obesity and diabetes. Hotamisligil GS, Diabetes 2005 54 Suppl 2 73 78 16306344
-
(2005)
Diabetes
, vol.54
, Issue.SUPPL 2
, pp. 1973-78
-
-
Hotamisligil, G.S.1
-
70
-
-
8544244084
-
PKC-θ knockout mice are protected from fat-induced insulin resistance
-
DOI 10.1172/JCI200422230
-
PKC-theta knockout mice are protected from fat-induced insulin resistance. Kim JK, Fillmore JJ, Sunshine MJ, Albrecht B, Higashimori T, Kim DW, Liu ZX, Soos TJ, Cline GW, O'Brien WR, et al. J Clin Invest 2004 114 6 823 827 15372106 (Pubitemid 39578741)
-
(2004)
Journal of Clinical Investigation
, vol.114
, Issue.6
, pp. 823-827
-
-
Kim, J.K.1
Fillmore, J.J.2
Sunshine, M.J.3
Albrecht, B.4
Higashimori, T.5
Kim, D.-W.6
Liu, Z.-X.7
Soos, T.J.8
Cline, G.W.9
O'Brien, W.R.10
Littman, D.R.11
Shulman, G.I.12
-
71
-
-
0035957949
-
Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins
-
11278339
-
Insulin stimulates PKCzeta -mediated phosphorylation of insulin receptor substrate-1 (IRS-1). A self-attenuated mechanism to negatively regulate the function of IRS proteins. Liu YF, Paz K, Herschkovitz A, Alt A, Tennenbaum T, Sampson SR, Ohba M, Kuroki T, LeRoith D, Zick Y, J Biol Chem 2001 276 17 14459 14465 11278339
-
(2001)
J Biol Chem
, vol.276
, Issue.17
, pp. 14459-14465
-
-
Liu, Y.F.1
Paz, K.2
Herschkovitz, A.3
Alt, A.4
Tennenbaum, T.5
Sampson, S.R.6
Ohba, M.7
Kuroki, T.8
Leroith, D.9
Zick, Y.10
-
72
-
-
33645112623
-
PKCtheta is a key player in the development of insulin resistance
-
10.1016/j.bbrc.2006.02.177 16545776
-
PKCtheta is a key player in the development of insulin resistance. Haasch D, Berg C, Clampit JE, Pederson T, Frost L, Kroeger P, Rondinone CM, Biochem Biophys Res Commun 2006 343 2 361 368 10.1016/j.bbrc.2006.02.177 16545776
-
(2006)
Biochem Biophys Res Commun
, vol.343
, Issue.2
, pp. 361-368
-
-
Haasch, D.1
Berg, C.2
Clampit, J.E.3
Pederson, T.4
Frost, L.5
Kroeger, P.6
Rondinone, C.M.7
-
73
-
-
33847404482
-
Inhibition of protein kinase Cε prevents hepatic insulin resistance in nonalcoholic fatty liver disease
-
DOI 10.1172/JCI30400
-
Inhibition of protein kinase Cepsilon prevents hepatic insulin resistance in nonalcoholic fatty liver disease. Samuel VT, Liu ZX, Wang A, Beddow SA, Geisler JG, Kahn M, Zhang XM, Monia BP, Bhanot S, Shulman GI, J Clin Invest 2007 117 3 739 745 10.1172/JCI30400 17318260 (Pubitemid 46348532)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.3
, pp. 739-745
-
-
Samuel, V.T.1
Liu, Z.-X.2
Wang, A.3
Beddow, S.A.4
Geisler, J.G.5
Kahn, M.6
Zhang, X.-M.7
Monia, B.P.8
Bhanot, S.9
Shulman, G.I.10
-
74
-
-
77957838795
-
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue
-
10.1172/JCI42845 20877011
-
Weight loss and lipolysis promote a dynamic immune response in murine adipose tissue. Kosteli A, Sugaru E, Haemmerle G, Martin JF, Lei J, Zechner R, Ferrante AW Jr, J Clin Invest 2010 120 10 3466 3479 10.1172/JCI42845 20877011
-
(2010)
J Clin Invest
, vol.120
, Issue.10
, pp. 3466-3479
-
-
Kosteli, A.1
Sugaru, E.2
Haemmerle, G.3
Martin, J.F.4
Lei, J.5
Zechner, R.6
Ferrante Jr., A.W.7
-
75
-
-
42449097289
-
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes
-
DOI 10.1038/nrm2391, PII NRM2391
-
Adipocyte dysfunctions linking obesity to insulin resistance and type 2 diabetes. Guilherme A, Virbasius JV, Puri V, Czech MP, Nat Rev Mol Cell Biol 2008 9 5 367 377 10.1038/nrm2391 18401346 (Pubitemid 351574198)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.5
, pp. 367-377
-
-
Guilherme, A.1
Virbasius, J.V.2
Puri, V.3
Czech, M.P.4
-
76
-
-
71449120759
-
Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment
-
10.1074/jbc.M109.041665 19740750
-
Glucocorticoids and thiazolidinediones interfere with adipocyte-mediated macrophage chemotaxis and recruitment. Patsouris D, Neels JG, Fan W, Li PP, Nguyen MT, Olefsky JM, J Biol Chem 2009 284 45 31223 31235 10.1074/jbc.M109. 041665 19740750
-
(2009)
J Biol Chem
, vol.284
, Issue.45
, pp. 31223-31235
-
-
Patsouris, D.1
Neels, J.G.2
Fan, W.3
Li, P.P.4
Nguyen, M.T.5
Olefsky, J.M.6
-
77
-
-
0035217707
-
Skeletal muscle lipid content and insulin resistance: Evidence for a paradox in endurance-trained athletes
-
DOI 10.1210/jc.86.12.5755
-
Skeletal Muscle Lipid Content and Insulin Resistance: Evidence for a Paradox in Endurance-Trained Athletes. Goodpaster BH, He J, Watkins S, Kelley DE, Journal of Clinical Endocrinology & Metabolism 2001 86 12 5755 5761 10.1210/jc.86.12.5755 22034475 (Pubitemid 33152620)
-
(2001)
Journal of Clinical Endocrinology and Metabolism
, vol.86
, Issue.12
, pp. 5755-5761
-
-
Goodpaster, B.H.1
He, J.2
Watkins, S.3
Kelley, D.E.4
-
78
-
-
4143060180
-
Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes
-
DOI 10.1152/ajpendo.00464.2003
-
Intramyocellular lipid content in type 2 diabetes patients compared with overweight sedentary men and highly trained endurance athletes. van Loon LJC, Koopman R, Manders R, van der Weegen W, van Kranenburg GP, Keizer HA, American Journal of Physiology-Endocrinology And Metabolism 2004 287 3 558 E565 10.1152/ajpendo.00464.2003 15165998 (Pubitemid 39095892)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.3
-
-
Van Loon, L.J.C.1
Koopman, R.2
Manders, R.3
Van Der Weegen, W.4
Van Kranenburg, G.P.5
Keizer, H.A.6
-
79
-
-
0037184925
-
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle
-
DOI 10.1074/jbc.M200958200
-
Mechanism by Which Fatty Acids Inhibit Insulin Activation of Insulin Receptor Substrate-1 (IRS-1)-associated Phosphatidylinositol 3-Kinase Activity in Muscle. Yu C, Chen Y, Cline GW, Zhang D, Zong H, Wang Y, Bergeron R, Kim JK, Cushman SW, Cooney GJ, et al. Journal of Biological Chemistry 2002 277 52 50230 50236 10.1074/jbc.M200958200 12006582 (Pubitemid 36042170)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.52
, pp. 50230-50236
-
-
Yu, C.1
Chen, Y.2
Cline, G.W.3
Zhang, D.4
Zong, H.5
Wang, Y.6
Bergeron, R.7
Kim, J.K.8
Cushman, S.W.9
Cooney, G.J.10
Atcheson, B.11
White, M.F.12
Kraegen, E.W.13
Shulman, G.I.14
-
80
-
-
0033927667
-
Cellular mechanisms of insulin resistance
-
Cellular mechanisms of insulin resistance. Shulman GI, J Clin Invest 2000 106 2 171 176 10.1172/JCI10583 10903330 (Pubitemid 30483118)
-
(2000)
Journal of Clinical Investigation
, vol.106
, Issue.2
, pp. 171-176
-
-
Shulman, G.I.1
-
81
-
-
0027459878
-
Adipose expression of tumor necrosis factor-α: Direct role in obesity-linked insulin resistance
-
Adipose expression of tumor necrosis factor-alpha: direct role in obesity-linked insulin resistance. Hotamisligil GS, Shargill NS, Spiegelman BM, Science 1993 259 87 91 10.1126/science.7678183 7678183 (Pubitemid 23036092)
-
(1993)
Science
, vol.259
, Issue.5091
, pp. 87-91
-
-
Hotamisligil, G.S.1
Shargill, N.S.2
Spiegelman, B.M.3
-
82
-
-
70349395711
-
Role of macrophage tissue infiltration in obesity and insulin resistance
-
10.1016/j.diabet.2009.05.001 19539513
-
Role of macrophage tissue infiltration in obesity and insulin resistance. Bourlier V, Bouloumie A, Diabetes Metab 2009 35 4 251 260 10.1016/j.diabet. 2009.05.001 19539513
-
(2009)
Diabetes Metab
, vol.35
, Issue.4
, pp. 251-260
-
-
Bourlier, V.1
Bouloumie, A.2
-
83
-
-
17844393870
-
Monocyte chemoattractant protein-1 release is higher in visceral than subcutaneous human adipose tissue (AT): Implication of macrophages resident in the AT
-
DOI 10.1210/jc.2004-1696
-
Monocyte Chemoattractant Protein-1 Release Is Higher in Visceral than Subcutaneous Human Adipose Tissue (AT): Implication of Macrophages Resident in the AT. Bruun JM, Lihn AS, Pedersen SB, Richelsen B, J Clin Endocrinol Metab 2005 90 4 2282 2289 10.1210/jc.2004-1696 15671098 (Pubitemid 40586275)
-
(2005)
Journal of Clinical Endocrinology and Metabolism
, vol.90
, Issue.4
, pp. 2282-2289
-
-
Bruun, J.M.1
Lihn, A.S.2
Pedersen, S.B.3
Richelsen, B.4
-
84
-
-
63649097100
-
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance
-
10.1016/j.cmet.2009.03.002 19356715
-
CXC ligand 5 is an adipose-tissue derived factor that links obesity to insulin resistance. Chavey C, Lazennec G, Lagarrigue S, Clape C, Iankova I, Teyssier J, Annicotte JS, Schmidt J, Mataki C, Yamamoto H, et al. Cell Metab 2009 9 4 339 349 10.1016/j.cmet.2009.03.002 19356715
-
(2009)
Cell Metab
, vol.9
, Issue.4
, pp. 339-349
-
-
Chavey, C.1
Lazennec, G.2
Lagarrigue, S.3
Clape, C.4
Iankova, I.5
Teyssier, J.6
Annicotte, J.S.7
Schmidt, J.8
Mataki, C.9
Yamamoto, H.10
-
85
-
-
33846410348
-
Macrophage-secreted factors impair human adipogenesis: Involvement of proinflammatory state in preadipocytes
-
DOI 10.1210/en.2006-0687
-
Macrophage-secreted factors impair human adipogenesis: involvement of proinflammatory state in preadipocytes. Lacasa D, Taleb S, Keophiphath M, Miranville A, Clement K, Endocrinology 2007 148 2 868 877 17082259 (Pubitemid 46143186)
-
(2007)
Endocrinology
, vol.148
, Issue.2
, pp. 868-877
-
-
Lacasa, D.1
Taleb, S.2
Keophiphath, M.3
Miranville, A.4
Clement, K.5
-
86
-
-
0036212849
-
Innate immune recognition
-
DOI 10.1146/annurev.immunol.20.083001.084359
-
Innate Immune Recognition. Janeway CA, Medzhitov R, Annual Review of Immunology 2002 20 1 197 216 10.1146/annurev.immunol.20.083001.084359 11861602 (Pubitemid 34293424)
-
(2002)
Annual Review of Immunology
, vol.20
, pp. 197-216
-
-
Janeway Jr., C.A.1
Medzhitov, R.2
-
87
-
-
34848829522
-
Obesity, innate immunity and gut inflammation
-
DOI 10.1097/MOG.0b013e3282c8c8d3, PII 0000157420071100000013
-
Obesity, innate immunity and gut inflammation. Karagiannides I, Pothoulakis C, Curr Opin Gastroenterol 2007 23 6 661 666 10.1097/MOG. 0b013e3282c8c8d3 17906444 (Pubitemid 47508797)
-
(2007)
Current Opinion in Gastroenterology
, vol.23
, Issue.6
, pp. 661-666
-
-
Karagiannides, I.1
Pothoulakis, C.2
-
88
-
-
35349016235
-
Recognition of microorganisms and activation of the immune response
-
DOI 10.1038/nature06246, PII NATURE06246
-
Recognition of microorganisms and activation of the immune response. Medzhitov R, Nature 2007 449 7164 819 826 10.1038/nature06246 17943118 (Pubitemid 47598622)
-
(2007)
Nature
, vol.449
, Issue.7164
, pp. 819-826
-
-
Medzhitov, R.1
-
89
-
-
58149347227
-
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes
-
10.2337/db08-0872 18829989
-
Phenotypic switching of adipose tissue macrophages with obesity is generated by spatiotemporal differences in macrophage subtypes. Lumeng CN, DelProposto JB, Westcott DJ, Saltiel AR, Diabetes 2008 57 12 3239 3246 10.2337/db08-0872 18829989
-
(2008)
Diabetes
, vol.57
, Issue.12
, pp. 3239-3246
-
-
Lumeng, C.N.1
Delproposto, J.B.2
Westcott, D.J.3
Saltiel, A.R.4
-
90
-
-
33847073149
-
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity
-
10.2337/db06-1076 17192460
-
Increased inflammatory properties of adipose tissue macrophages recruited during diet-induced obesity. Lumeng CN, Deyoung SM, Bodzin JL, Saltiel AR, Diabetes 2007 56 1 16 23 10.2337/db06-1076 17192460
-
(2007)
Diabetes
, vol.56
, Issue.1
, pp. 16-23
-
-
Lumeng, C.N.1
Deyoung, S.M.2
Bodzin, J.L.3
Saltiel, A.R.4
-
91
-
-
33846026712
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization
-
DOI 10.1172/JCI29881
-
Obesity induces a phenotypic switch in adipose tissue macrophage polarization. Lumeng CN, Bodzin JL, Saltiel AR, J Clin Invest 2007 117 1 175 184 10.1172/JCI29881 17200717 (Pubitemid 46048464)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 175-184
-
-
Lumeng, C.N.1
Bodzin, J.L.2
Saltiel, A.R.3
-
92
-
-
77953268611
-
Alternative activation of macrophages: Mechanism and functions
-
Alternative activation of macrophages: mechanism and functions. Gordon S, Martinez FO, Immunity 32 5 593 604
-
Immunity
, vol.32
, Issue.5
, pp. 593-604
-
-
Gordon, S.1
Martinez, F.O.2
-
93
-
-
67650485985
-
Alternative activation of macrophages: An immunologic functional perspective
-
10.1146/annurev.immunol.021908.132532 19105661
-
Alternative activation of macrophages: an immunologic functional perspective. Martinez FO, Helming L, Gordon S, Annu Rev Immunol 2009 27 451 483 10.1146/annurev.immunol.021908.132532 19105661
-
(2009)
Annu Rev Immunol
, vol.27
, pp. 451-483
-
-
Martinez, F.O.1
Helming, L.2
Gordon, S.3
-
94
-
-
34548354722
-
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production
-
DOI 10.1038/sj.ijo.0803632, PII 0803632
-
Human adipose tissue macrophages are of an anti-inflammatory phenotype but capable of excessive pro-inflammatory mediator production. Zeyda M, Farmer D, Todoric J, Aszmann O, Speiser M, Gyori G, Zlabinger GJ, Stulnig TM, Int J Obes 2007 31 9 1420 1428 10.1038/sj.ijo.0803632 (Pubitemid 47339934)
-
(2007)
International Journal of Obesity
, vol.31
, Issue.9
, pp. 1420-1428
-
-
Zeyda, M.1
Farmer, D.2
Todoric, J.3
Aszmann, O.4
Speiser, M.5
Gyori, G.6
Zlabinger, G.J.7
Stulnig, T.M.8
-
95
-
-
34548477639
-
Adipose tissue macrophages
-
DOI 10.1016/j.imlet.2007.07.003, PII S0165247807001502
-
Adipose tissue macrophages. Zeyda M, Stulnig TM, Immunology Letters 2007 112 2 61 67 10.1016/j.imlet.2007.07.003 17719095 (Pubitemid 47379852)
-
(2007)
Immunology Letters
, vol.112
, Issue.2
, pp. 61-67
-
-
Zeyda, M.1
Stulnig, T.M.2
-
96
-
-
30044434256
-
The mononuclear phagocyte system
-
DOI 10.1016/j.coi.2005.11.008, PII S0952791505002013, Innate Immunity/Antigen Processing and Recognition
-
The mononuclear phagocyte system. Hume DA, Curr Opin Immunol 2006 18 1 49 53 10.1016/j.coi.2005.11.008 16338128 (Pubitemid 43049647)
-
(2006)
Current Opinion in Immunology
, vol.18
, Issue.1
, pp. 49-53
-
-
Hume, D.A.1
-
97
-
-
54449093241
-
Differentiation and heterogeneity in the mononuclear phagocyte system
-
10.1038/mi.2008.36 19079210
-
Differentiation and heterogeneity in the mononuclear phagocyte system. Hume DA, Mucosal Immunol 2008 1 6 432 441 10.1038/mi.2008.36 19079210
-
(2008)
Mucosal Immunol
, vol.1
, Issue.6
, pp. 432-441
-
-
Hume, D.A.1
-
98
-
-
36249032544
-
The macrophage: Past, present and future
-
17972350
-
The macrophage: past, present and future. Gordon S, Eur J Immunol 2007 37 Suppl 1 9 17 17972350
-
(2007)
Eur J Immunol
, vol.37
, Issue.SUPPL 1
, pp. 199-17
-
-
Gordon, S.1
-
99
-
-
33845975254
-
Macrophage heterogeneity and tissue lipids
-
DOI 10.1172/JCI30992
-
Macrophage heterogeneity and tissue lipids. Gordon S, J Clin Invest 2007 117 1 89 93 17200712 (Pubitemid 46048455)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.1
, pp. 89-93
-
-
Gordon, S.1
-
100
-
-
68649111832
-
Alternative activation of macrophages: Immune function and cellular biology
-
10.1016/j.imbio.2008.11.009 19264378
-
Alternative activation of macrophages: immune function and cellular biology. Varin A, Gordon S, Immunobiology 2009 214 7 630 641 10.1016/j.imbio.2008.11.009 19264378
-
(2009)
Immunobiology
, vol.214
, Issue.7
, pp. 630-641
-
-
Varin, A.1
Gordon, S.2
-
101
-
-
78651073627
-
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity
-
10.1073/pnas.1009152108 21149710
-
IL-4/STAT6 immune axis regulates peripheral nutrient metabolism and insulin sensitivity. Ricardo-Gonzalez RR, Red Eagle A, Odegaard JI, Jouihan H, Morel CR, Heredia JE, Mukundan L, Wu D, Locksley RM, Chawla A, Proc Natl Acad Sci USA 2010 107 52 22617 22622 10.1073/pnas.1009152108 21149710
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.52
, pp. 22617-22622
-
-
Ricardo-Gonzalez, R.R.1
Red Eagle, A.2
Odegaard, J.I.3
Jouihan, H.4
Morel, C.R.5
Heredia, J.E.6
Mukundan, L.7
Wu, D.8
Locksley, R.M.9
Chawla, A.10
-
102
-
-
34347354309
-
Macrophage-specific PPARγ controls alternative activation and improves insulin resistance
-
DOI 10.1038/nature05894, PII NATURE05894
-
Macrophage-specific PPARgamma controls alternative activation and improves insulin resistance. Odegaard JI, Ricardo-Gonzalez RR, Goforth MH, Morel CR, Subramanian V, Mukundan L, Red Eagle A, Vats D, Brombacher F, Ferrante AW, et al. Nature 2007 447 7148 1116 1120 10.1038/nature05894 17515919 (Pubitemid 47014427)
-
(2007)
Nature
, vol.447
, Issue.7148
, pp. 1116-1120
-
-
Odegaard, J.I.1
Ricardo-Gonzalez, R.R.2
Goforth, M.H.3
Morel, C.R.4
Subramanian, V.5
Mukundan, L.6
Eagle, A.R.7
Vats, D.8
Brombacher, F.9
Ferrante, A.W.10
Chawla, A.11
-
103
-
-
79751496064
-
Alternative macrophage activation and metabolism
-
10.1146/annurev-pathol-011110-130138 21034223
-
Alternative macrophage activation and metabolism. Odegaard JI, Chawla A, Annu Rev Pathol 2011 6 275 297 10.1146/annurev-pathol-011110-130138 21034223
-
(2011)
Annu Rev Pathol
, vol.6
, pp. 275-297
-
-
Odegaard, J.I.1
Chawla, A.2
-
104
-
-
0032871377
-
Leukocyte adhesion molecules in atherogenesis
-
DOI 10.1016/S0009-8981(99)00102-3, PII S0009898199001023
-
Leukocyte adhesion molecules in atherogenesis. Cybulsky MI, Lichtman AH, Hajra L, Iiyama K, Clin Chim Acta 1999 286 1-2 207 218 10.1016/S0009-8981(99) 00102-3 10511293 (Pubitemid 29406109)
-
(1999)
Clinica Chimica Acta
, vol.286
, Issue.1-2
, pp. 207-218
-
-
Cybulsky, M.I.1
Lichtman, A.H.2
Hajra, L.3
Iiyama, K.4
-
105
-
-
34548230927
-
Getting to the site of inflammation: The leukocyte adhesion cascade updated
-
DOI 10.1038/nri2156, PII NRI2156
-
Getting to the site of inflammation: the leukocyte adhesion cascade updated. Ley K, Laudanna C, Cybulsky MI, Nourshargh S, Nat Rev Immunol 2007 7 9 678 689 10.1038/nri2156 17717539 (Pubitemid 47327397)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.9
, pp. 678-689
-
-
Ley, K.1
Laudanna, C.2
Cybulsky, M.I.3
Nourshargh, S.4
-
106
-
-
70449113184
-
Human adipose tissue macrophages: M1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss
-
10.1210/jc.2009-0925 19837929
-
Human adipose tissue macrophages: m1 and m2 cell surface markers in subcutaneous and omental depots and after weight loss. Aron-Wisnewsky J, Tordjman J, Poitou C, Darakhshan F, Hugol D, Basdevant A, Aissat A, Guerre-Millo M, Clement K, J Clin Endocrinol Metab 2009 94 11 4619 4623 10.1210/jc.2009-0925 19837929
-
(2009)
J Clin Endocrinol Metab
, vol.94
, Issue.11
, pp. 4619-4623
-
-
Aron-Wisnewsky, J.1
Tordjman, J.2
Poitou, C.3
Darakhshan, F.4
Hugol, D.5
Basdevant, A.6
Aissat, A.7
Guerre-Millo, M.8
Clement, K.9
-
107
-
-
77952887297
-
Unravelling mononuclear phagocyte heterogeneity
-
Unravelling mononuclear phagocyte heterogeneity. Geissmann Fdr, Gordon S, Hume DA, Mowat AM, Randolph GJ, Nat Rev Immunol 10 6 453 460
-
Nat Rev Immunol
, vol.10
, Issue.6
, pp. 453-460
-
-
Geissmann, F.1
Gordon, S.2
Hume, D.A.3
Mowat, A.M.4
Randolph, G.J.5
-
108
-
-
0038660699
-
Preadipocyte conversion to macrophage: Evidence of plasticity
-
DOI 10.1074/jbc.M210811200
-
Preadipocyte Conversion to Macrophage. Charriére G, Cousin B, Arnaud E, André M, Bacou F, Pénicaud L, Casteilla L, Journal of Biological Chemistry 2003 278 11 9850 9855 10.1074/jbc.M210811200 12519759 (Pubitemid 36800488)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.11
, pp. 9850-9855
-
-
Charriere, G.1
Cousin, B.2
Arnaud, E.3
Andre, M.4
Bacou, F.5
Penicaud, L.6
Casteilla, L.7
-
109
-
-
0035124840
-
Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity
-
DOI 10.1002/1097-4652(2001)9999:9999<000::AID-JCP1038>3.0.CO;2-T
-
Altered macrophage-like functions of preadipocytes in inflammation and genetic obesity. Cousin B, Andre M, Casteilla L, Penicaud L, J Cell Physiol 2001 186 3 380 386 10.1002/1097-4652(2001)9999:9999<000::AID-JCP1038>3.0.CO;2- T 11169977 (Pubitemid 32147721)
-
(2001)
Journal of Cellular Physiology
, vol.186
, Issue.3
, pp. 380-386
-
-
Cousin, B.1
Andre, M.2
Casteilla, L.3
Penicaud, L.4
-
110
-
-
0033007024
-
A role for preadipocytes as macrophage-like cells
-
A role for preadipocytes as macrophage-like cells. Cousin B, Munoz O, Andre M, Fontanilles AM, Dani C, Cousin JL, Laharrague P, Casteilla L, Penicaud L, FASEB J 1999 13 2 305 312 9973318 (Pubitemid 29072407)
-
(1999)
FASEB Journal
, vol.13
, Issue.2
, pp. 305-312
-
-
Cousin, B.1
Munoz, O.2
Andre, M.3
Fontanilles, A.M.4
Dani, C.5
Cousin, J.L.6
Laharrague, P.7
Casteilla, L.8
Penicaud, L.9
-
111
-
-
0021723557
-
Monocytic origin of foam cells in human atherosclerotic plaques
-
DOI 10.1016/0021-9150(84)90127-8
-
Monocytic origin of foam cells in human atherosclerotic plaques. Aqel NM, Ball RY, Waldmann H, Mitchinson MJ, Atherosclerosis 1984 53 3 265 271 10.1016/0021-9150(84)90127-8 6397199 (Pubitemid 15194149)
-
(1984)
Atherosclerosis
, vol.53
, Issue.3
, pp. 265-271
-
-
Aqel, N.M.1
Ball, R.Y.2
Waldmann, H.3
Mitchinson, M.J.4
-
112
-
-
1242283935
-
Triglyceride-rich lipoproteins inhibit cholesterol efflux to apolipoprotein (apo) A1 from human macrophage foam cells
-
DOI 10.1016/j.atherosclerosis.2003.12.001
-
Triglyceride-rich lipoproteins inhibit cholesterol efflux to apolipoprotein (apo) A1 from human macrophage foam cells. Palmer AM, Murphy N, Graham A, Atherosclerosis 2004 173 1 27 38 10.1016/j.atherosclerosis.2003.12.001 15177121 (Pubitemid 38224193)
-
(2004)
Atherosclerosis
, vol.173
, Issue.1
, pp. 27-38
-
-
Palmer, A.M.1
Murphy, N.2
Graham, A.3
-
113
-
-
57649165720
-
Adiponectin reduces lipid accumulation in macrophage foam cells
-
10.1016/j.atherosclerosis.2008.04.011 18511057
-
Adiponectin reduces lipid accumulation in macrophage foam cells. Tian L, Luo N, Klein RL, Chung BH, Garvey WT, Fu Y, Atherosclerosis 2009 202 1 152 161 10.1016/j.atherosclerosis.2008.04.011 18511057
-
(2009)
Atherosclerosis
, vol.202
, Issue.1
, pp. 152-161
-
-
Tian, L.1
Luo, N.2
Klein, R.L.3
Chung, B.H.4
Garvey, W.T.5
Fu, Y.6
-
114
-
-
0347985272
-
Obesity-induced inflammatory changes in adipose tissue
-
DOI 10.1172/JCI200320514
-
Obesity-induced inflammatory changes in adipose tissue. Wellen KE, Hotamisligil GS, J Clin Invest 2003 112 12 1785 1788 14679172 (Pubitemid 38063699)
-
(2003)
Journal of Clinical Investigation
, vol.112
, Issue.12
, pp. 1785-1788
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
115
-
-
18244370762
-
Inflammation, stress, and diabetes
-
DOI 10.1172/JCI200525102
-
Inflammation, stress, and diabetes. Wellen KE, Hotamisligil GS, J Clin Invest 2005 115 5 1111 1119 15864338 (Pubitemid 40629025)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.5
, pp. 1111-1119
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
116
-
-
0035430576
-
Effects of pioglitazone on adipose tissue remodeling within the setting of obesity and insulin resistance
-
Effects of Pioglitazone on Adipose Tissue Remodeling Within the Setting of Obesity and Insulin Resistance. de Souza CJ, Eckhardt M, Gagen K, Dong M, Chen W, Laurent D, Burkey BF, Diabetes 2001 50 8 1863 1871 10.2337/diabetes.50. 8.1863 11473050 (Pubitemid 33641608)
-
(2001)
Diabetes
, vol.50
, Issue.8
, pp. 1863-1871
-
-
De Souza, C.J.1
Eckhardt, M.2
Gagen, K.3
Dong, M.4
Chen, W.5
Laurent, D.6
Burkey, B.F.7
-
117
-
-
77954672503
-
Adipose tissue macrophages: Their role in adipose tissue remodeling
-
10.1189/jlb.0210072 20360405
-
Adipose tissue macrophages: their role in adipose tissue remodeling. Suganami T, Ogawa Y, Journal of Leukocyte Biology 2010 88 1 33 39 10.1189/jlb.0210072 20360405
-
(2010)
Journal of Leukocyte Biology
, vol.88
, Issue.1
, pp. 33-39
-
-
Suganami, T.1
Ogawa, Y.2
-
118
-
-
0032925340
-
Mechanisms of TNF-alpha-induced insulin resistance
-
10.1055/s-0029-1212086 10320052
-
Mechanisms of TNF-alpha-induced insulin resistance. Hotamisligil GS, Exp Clin Endocrinol Diabetes 1999 107 2 119 125 10.1055/s-0029-1212086 10320052
-
(1999)
Exp Clin Endocrinol Diabetes
, vol.107
, Issue.2
, pp. 119-125
-
-
Hotamisligil, G.S.1
-
119
-
-
0033694663
-
Molecular mechanisms of insulin resistance and the role of the adipocyte
-
11126235
-
Molecular mechanisms of insulin resistance and the role of the adipocyte. Hotamisligil GS, Int J Obes Relat Metab Disord 2000 24 Suppl 4 23 27 11126235
-
(2000)
Int J Obes Relat Metab Disord
, vol.24
, Issue.SUPPL 4
, pp. 1923-27
-
-
Hotamisligil, G.S.1
-
120
-
-
0035856949
-
Insulin signalling and the regulation of glucose and lipid metabolism
-
DOI 10.1038/414799a
-
Insulin signalling and the regulation of glucose and lipid metabolism. Saltiel AR, Kahn CR, Nature 2001 414 6865 799 806 10.1038/414799a 11742412 (Pubitemid 34000783)
-
(2001)
Nature
, vol.414
, Issue.6865
, pp. 799-806
-
-
Saltiel, A.R.1
Kahn, C.R.2
-
121
-
-
0036327970
-
Impairment of insulin signaling in human skeletal muscle cells by co-culture with human adipocytes
-
Impairment of Insulin Signaling in Human Skeletal Muscle Cells by Co-Culture With Human Adipocytes. Dietze D, Koenen M, Röhrig K, Horikoshi H, Hauner H, Eckel J, Diabetes 2002 51 8 2369 2376 10.2337/diabetes.51.8.2369 12145147 (Pubitemid 34827384)
-
(2002)
Diabetes
, vol.51
, Issue.8
, pp. 2369-2376
-
-
Dietze, D.1
Koenen, M.2
Rohrig, K.3
Horikoshi, H.4
Hanner, H.5
Eckel, J.6
-
122
-
-
58149394230
-
Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals
-
19056573
-
Regulation of skeletal muscle mitochondrial fatty acid metabolism in lean and obese individuals. Holloway GP, Bonen A, Spriet LL, Am J Clin Nutr 2009 89 1 455S 462 19056573
-
(2009)
Am J Clin Nutr
, vol.89
, Issue.1
-
-
Holloway, G.P.1
Bonen, A.2
Spriet, L.L.3
-
123
-
-
58249117853
-
Palmitate- and lipopolysaccharide-activated macrophages evoke contrasting insulin responses in muscle cells
-
18840759
-
Palmitate- and lipopolysaccharide-activated macrophages evoke contrasting insulin responses in muscle cells. Samokhvalov V, Bilan PJ, Schertzer JD, Antonescu CN, Klip A, Am J Physiol Endocrinol Metab 2009 296 1 37 46 18840759
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, Issue.1
, pp. 537-46
-
-
Samokhvalov, V.1
Bilan, P.J.2
Schertzer, J.D.3
Antonescu, C.N.4
Klip, A.5
-
124
-
-
70350561703
-
Interleukin-10 prevents diet-induced insulin resistance by attenuating macrophage and cytokine response in skeletal muscle
-
10.2337/db08-1261 19690064
-
Interleukin-10 Prevents Diet-Induced Insulin Resistance by Attenuating Macrophage and Cytokine Response in Skeletal Muscle. Hong E-G, Ko HJ, Cho Y-R, Kim H-J, Ma Z, Yu TY, Friedline RH, Kurt-Jones E, Finberg R, Fischer MA, et al. Diabetes 2009 58 11 2525 2535 10.2337/db08-1261 19690064
-
(2009)
Diabetes
, vol.58
, Issue.11
, pp. 2525-2535
-
-
Hong, E.-G.1
Ko, H.J.2
Cho, Y.-R.3
Kim, H.-J.4
Ma, Z.5
Yu, T.Y.6
Friedline, R.H.7
Kurt-Jones, E.8
Finberg, R.9
Fischer, M.A.10
-
125
-
-
34249907880
-
Macrophage PPARγ is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones
-
DOI 10.1172/JCI31561
-
Macrophage PPAR gamma is required for normal skeletal muscle and hepatic insulin sensitivity and full antidiabetic effects of thiazolidinediones. Hevener AL, Olefsky JM, Reichart D, Nguyen MT, Bandyopadyhay G, Leung HY, Watt MJ, Benner C, Febbraio MA, Nguyen AK, et al. J Clin Invest 2007 117 6 1658 1669 10.1172/JCI31561 17525798 (Pubitemid 46871350)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.6
, pp. 1658-1669
-
-
Hevener, A.L.1
Olefsky, J.M.2
Reichart, D.3
Nguyen, M.T.A.4
Bandyopadyhay, G.5
Leung, H.-Y.6
Watt, M.J.7
Benner, C.8
Febbraio, M.A.9
Nguyen, A.-K.10
Folian, B.11
Subramaniam, S.12
Gonzalez, F.J.13
Glass, C.K.14
Ricote, M.15
-
126
-
-
52749092267
-
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals
-
10.1016/j.cmet.2008.08.015 18840360
-
Ablation of CD11c-positive cells normalizes insulin sensitivity in obese insulin resistant animals. Patsouris D, Li PP, Thapar D, Chapman J, Olefsky JM, Neels JG, Cell Metab 2008 8 4 301 309 10.1016/j.cmet.2008.08.015 18840360
-
(2008)
Cell Metab
, vol.8
, Issue.4
, pp. 301-309
-
-
Patsouris, D.1
Li, P.P.2
Thapar, D.3
Chapman, J.4
Olefsky, J.M.5
Neels, J.G.6
-
127
-
-
66849093697
-
Muscle inflammatory response and insulin resistance: Synergistic interaction between macrophages and fatty acids leads to impaired insulin action
-
10.1152/ajpendo.90885.2008 19336660
-
Muscle inflammatory response and insulin resistance: synergistic interaction between macrophages and fatty acids leads to impaired insulin action. Varma V, Yao-Borengasser A, Rasouli N, Nolen GT, Phanavanh B, Starks T, Gurley C, Simpson P, McGehee RE Jr, Kern PA, et al. Am J Physiol Endocrinol Metab 2009 296 6 1300 1310 10.1152/ajpendo.90885.2008 19336660
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
, Issue.6
, pp. 51300-1310
-
-
Varma, V.1
Yao-Borengasser, A.2
Rasouli, N.3
Nolen, G.T.4
Phanavanh, B.5
Starks, T.6
Gurley, C.7
Simpson, P.8
McGehee Jr., R.E.9
Kern, P.A.10
-
128
-
-
23644446750
-
Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: Association with cytokine expression, insulin resistance, and reduction by pioglitazone
-
DOI 10.2337/diabetes.54.8.2305
-
Expression of CD68 and macrophage chemoattractant protein-1 genes in human adipose and muscle tissues: association with cytokine expression, insulin resistance, and reduction by pioglitazone. Di Gregorio GB, Yao-Borengasser A, Rasouli N, Varma V, Lu T, Miles LM, Ranganathan G, Peterson CA, McGehee RE, Kern PA, Diabetes 2005 54 8 2305 2313 10.2337/diabetes.54.8.2305 16046295 (Pubitemid 41134256)
-
(2005)
Diabetes
, vol.54
, Issue.8
, pp. 2305-2313
-
-
Di Gregorio, G.B.1
Yao-Borengasser, A.2
Rasouli, N.3
Varma, V.4
Lu, T.5
Miles, L.M.6
Ranganathan, G.7
Peterson, C.A.8
McGehee, R.E.9
Kern, P.A.10
-
129
-
-
33646397556
-
Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects
-
10.1152/ajpendo.00506.2005 16352667
-
Diet and exercise reduce low-grade inflammation and macrophage infiltration in adipose tissue but not in skeletal muscle in severely obese subjects. Bruun JM, Helge JW, Richelsen B, Stallknecht B, Am J Physiol Endocrinol Metab 2006 290 5 961 967 10.1152/ajpendo.00506.2005 16352667
-
(2006)
Am J Physiol Endocrinol Metab
, vol.290
, Issue.5
, pp. 5961-967
-
-
Bruun, J.M.1
Helge, J.W.2
Richelsen, B.3
Stallknecht, B.4
-
130
-
-
62749138513
-
Adipose tissue inflammation and liver pathology in human obesity
-
PT2,19195627
-
Adipose tissue inflammation and liver pathology in human obesity. Tordjman J, Guerre-Millo M, Clement K, Diabetes Metab 2008 34 6 Pt 2 658 663 19195627
-
(2008)
Diabetes Metab
, vol.34
, Issue.6
, pp. 658-663
-
-
Tordjman, J.1
Guerre-Millo, M.2
Clement, K.3
-
131
-
-
73349127065
-
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling
-
10.1016/j.bbadis.2009.08.007
-
Loss of Kupffer cells in diet-induced obesity is associated with increased hepatic steatosis, STAT3 signaling, and further decreases in insulin signaling. Clementi AH, Gaudy AM, van Rooijen N, Pierce RH, Mooney RA, Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 2009 1792 11 1062 1072 10.1016/j.bbadis.2009.08.007
-
(2009)
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
, vol.1792
, Issue.11
, pp. 1062-1072
-
-
Clementi, A.H.1
Gaudy, A.M.2
Van Rooijen, N.3
Pierce, R.H.4
Mooney, R.A.5
-
132
-
-
77951146612
-
C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis
-
10.2337/db09-1403 20103702
-
C-C chemokine receptor 2 (CCR2) regulates the hepatic recruitment of myeloid cells that promote obesity-induced hepatic steatosis. Obstfeld AE, Sugaru E, Thearle M, Francisco AM, Gayet C, Ginsberg HN, Ables EV, Ferrante AW Jr, Diabetes 2010 59 4 916 925 10.2337/db09-1403 20103702
-
(2010)
Diabetes
, vol.59
, Issue.4
, pp. 916-925
-
-
Obstfeld, A.E.1
Sugaru, E.2
Thearle, M.3
Francisco, A.M.4
Gayet, C.5
Ginsberg, H.N.6
Ables, E.V.7
Ferrante Jr., A.W.8
-
133
-
-
64149125118
-
Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy
-
10.1007/s00125-009-1309-8 19277603
-
Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy. Yang S, IglayReger H, Kadouh H, Bodary P, Diabetologia 2009 52 5 972 981 10.1007/s00125-009-1309-8 19277603
-
(2009)
Diabetologia
, vol.52
, Issue.5
, pp. 972-981
-
-
Yang, S.1
Iglayreger, H.2
Kadouh, H.3
Bodary, P.4
-
134
-
-
74549167737
-
Dietary and genetic obesity promote liver inflammation and tumorigenesis by enhancing IL-6 and TNF expression
-
10.1016/j.cell.2009.12.052 20141834
-
Dietary and Genetic Obesity Promote Liver Inflammation and Tumorigenesis by Enhancing IL-6 and TNF Expression. Park EJ, Lee JH, Yu G-Y, He G, Ali SR, Holzer RG, sterreicher CH, Takahashi H, Karin M, Cell 2010 140 2 197 208 10.1016/j.cell.2009.12.052 20141834
-
(2010)
Cell
, vol.140
, Issue.2
, pp. 197-208
-
-
Park, E.J.1
Lee, J.H.2
Yu, G.-Y.3
He, G.4
Ali, S.R.5
Holzer, R.G.6
Sterreicher, C.H.7
Takahashi, H.8
Karin, M.9
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