메뉴 건너뛰기




Volumn 12, Issue 11, 2011, Pages 638-651

Common cellular and molecular mechanisms in obesity and drug addiction

Author keywords

[No Author keywords available]

Indexed keywords

AMPHETAMINE; DOPAMINE RECEPTOR; GHRELIN; GLUCAGON LIKE PEPTIDE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN; LEPTIN; NEUROPEPTIDE; NICOTINE; OREXIN 1 RECEPTOR; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA AGONIST; PHOSPHATIDYLINOSITOL 3 KINASE; PROOPIOMELANOCORTIN; ROSIGLITAZONE; SIRTUIN 1;

EID: 80054800194     PISSN: 1471003X     EISSN: 14710048     Source Type: Journal    
DOI: 10.1038/nrn3105     Document Type: Review
Times cited : (312)

References (170)
  • 1
    • 79951699573 scopus 로고    scopus 로고
    • Reward mechanisms in obesity: New insights and future directions
    • Kenny, P. J. Reward mechanisms in obesity: new insights and future directions. Neuron 69, 664-679 (2011).
    • (2011) Neuron , vol.69 , pp. 664-679
    • Kenny, P.J.1
  • 2
    • 0004444325 scopus 로고
    • On the instrumental conditioned reaction evoked by electrical stimulation of the hypothalamus
    • Wyrwicka, W., Dobrzecka, C. & Tarnecki, R. On the instrumental conditioned reaction evoked by electrical stimulation of the hypothalamus. Science 130, 336-337 (1959).
    • (1959) Science , vol.130 , pp. 336-337
    • Wyrwicka, W.1    Dobrzecka, C.2    Tarnecki, R.3
  • 3
    • 33747364953 scopus 로고    scopus 로고
    • Pharmacological characterization of high-fat feeding induced by opioid stimulation of the ventral striatum
    • Will, M. J., Pratt, W. E. & Kelley, A. E. Pharmacological characterization of high-fat feeding induced by opioid stimulation of the ventral striatum. Physiol. Behav. 89, 226-234 (2006).
    • (2006) Physiol. Behav , vol.89 , pp. 226-234
    • Will, M.J.1    Pratt, W.E.2    Kelley, A.E.3
  • 4
    • 0036900527 scopus 로고    scopus 로고
    • Biobehavioral influences on energy intake and adult weight gain
    • McCrory, M. A., Suen, V. M. & Roberts, S. B. Biobehavioral influences on energy intake and adult weight gain. J. Nutr. 132, 3830S-3834S (2002). (Pubitemid 35435075)
    • (2002) Journal of Nutrition , vol.132 , Issue.12
    • McCrory, M.A.1    Suen, V.M.M.2    Roberts, S.B.3
  • 5
    • 70149085622 scopus 로고    scopus 로고
    • Increased portion size leads to a sustained increase in energy intake over 4 d in normal-weight and overweight men and women
    • Kelly, M. T. et al. Increased portion size leads to a sustained increase in energy intake over 4 d in normal-weight and overweight men and women. Br. J. Nutr. 102, 470-477 (2009).
    • (2009) Br. J. Nutr , vol.102 , pp. 470-477
    • Kelly, M.T.1
  • 6
    • 77953539238 scopus 로고    scopus 로고
    • The plausibility of sugar addiction and its role in obesity and eating disorders
    • Benton, D. The plausibility of sugar addiction and its role in obesity and eating disorders. Clin. Nutr. 29, 288-303 (2010).
    • (2010) Clin. Nutr , vol.29 , pp. 288-303
    • Benton, D.1
  • 8
    • 0029656176 scopus 로고    scopus 로고
    • Probing the causes of high-fat diet hyperphagia: A mechanistic and behavioral dissection
    • Warwick, Z. S. Probing the causes of high-fat diet hyperphagia: a mechanistic and behavioral dissection. Neurosci. Biobehav. Rev. 20, 155-161 (1996). (Pubitemid 126682124)
    • (1996) Neuroscience and Biobehavioral Reviews , vol.20 , Issue.1 , pp. 155-161
    • Warwick, Z.S.1
  • 9
    • 0033780625 scopus 로고    scopus 로고
    • The role of gastrointestinal vagal afferents in the control of food intake: Current prospects
    • Schwartz, G. J. The role of gastrointestinal vagal afferents in the control of food intake: current prospects. Nutrition 16, 866-873 (2000).
    • (2000) Nutrition , vol.16 , pp. 866-873
    • Schwartz, G.J.1
  • 11
    • 0034852258 scopus 로고    scopus 로고
    • Changes in brain activity related to eating chocolate: From pleasure to aversion
    • Small, D. M., Zatorre, R. J., Dagher, A., Evans, A. C. & Jones-Gotman, M. Changes in brain activity related to eating chocolate: from pleasure to aversion. Brain 124, 1720-1733 (2001). (Pubitemid 32845434)
    • (2001) Brain , vol.124 , Issue.9 , pp. 1720-1733
    • Small, D.M.1    Zatorre, R.J.2    Dagher, A.3    Evans, A.C.4    Jones-Gotman, M.5
  • 12
    • 78650752631 scopus 로고    scopus 로고
    • Reward dopamine and the control of food intake: Implications for obesity
    • Volkow, N. D., Wang, G. J. & Baler, R. D. Reward, dopamine and the control of food intake: implications for obesity. Trends Cogn. Sci. 15, 37-46 (2011).
    • (2011) Trends Cogn. Sci , vol.15 , pp. 37-46
    • Volkow, N.D.1    Wang, G.J.2    Baler, R.D.3
  • 15
    • 57649198133 scopus 로고    scopus 로고
    • Activation of hindbrain neurons in response to gastrointestinal lipid is attenuated by high fat, high energy diets in mice prone to diet-induced obesity
    • Donovan, M. J., Paulino, G. & Raybould, H. E. Activation of hindbrain neurons in response to gastrointestinal lipid is attenuated by high fat, high energy diets in mice prone to diet-induced obesity. Brain Res. 1248, 136-140 (2009).
    • (2009) Brain Res , vol.1248 , pp. 136-140
    • Donovan, M.J.1    Paulino, G.2    Raybould, H.E.3
  • 16
    • 50249140053 scopus 로고    scopus 로고
    • Noradrenergic transmission in the extended amygdala: Role in increased drug-seeking and relapse during protracted drug abstinence
    • Smith, R. J. & Aston-Jones, G. Noradrenergic transmission in the extended amygdala: role in increased drug-seeking and relapse during protracted drug abstinence. Brain Struct. Funct. 213, 43-61 (2008).
    • (2008) Brain Struct. Funct , vol.213 , pp. 43-61
    • Smith, R.J.1    Aston-Jones, G.2
  • 17
    • 34548060394 scopus 로고    scopus 로고
    • Stress, dysregulation of drug reward pathways, and the transition to drug dependence
    • DOI 10.1176/appi.ajp.2007.05030503
    • Koob, G. & Kreek, M. J. Stress, dysregulation of drug reward pathways, and the transition to drug dependence. Am. J. Psychiatry 164, 1149-1159 (2007). (Pubitemid 47292402)
    • (2007) American Journal of Psychiatry , vol.164 , Issue.8 , pp. 1149-1159
    • Koob, G.1    Kreek, M.J.2
  • 18
    • 33749538094 scopus 로고    scopus 로고
    • Nicotine suppression of gustatory responses of neurons in the nucleus of the solitary tract
    • DOI 10.1152/jn.00345.2006
    • Simons, C. T., Boucher, Y., Carstens, M. I. & Carstens, E. Nicotine suppression of gustatory responses of neurons in the nucleus of the solitary tract. J. Neurophysiol. 96, 1877-1886 (2006). (Pubitemid 44527443)
    • (2006) Journal of Neurophysiology , vol.96 , Issue.4 , pp. 1877-1886
    • Simons, C.T.1    Boucher, Y.2    Carstens, M.I.3    Carstens, E.4
  • 19
    • 79960630209 scopus 로고    scopus 로고
    • Differentiating the rapid actions of cocaine
    • Wise, R. A. & Kiyatkin, E. A. Differentiating the rapid actions of cocaine. Nature Rev. Neurosci. 12, 479-484 (2011).
    • (2011) Nature Rev. Neurosci , vol.12 , pp. 479-484
    • Wise, R.A.1    Kiyatkin, E.A.2
  • 20
    • 80051789412 scopus 로고    scopus 로고
    • Critical role of peripheral actions of intravenous nicotine in mediating its central effects
    • Lenoir, M. & Kiyatkin, E. A. Critical role of peripheral actions of intravenous nicotine in mediating its central effects. Neuropsychopharmacology 36, 2125-2138 (2011).
    • (2011) Neuropsychopharmacology , vol.36 , pp. 2125-2138
    • Lenoir, M.1    Kiyatkin, E.A.2
  • 21
    • 33144478267 scopus 로고    scopus 로고
    • Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward
    • DOI 10.1126/science.1119311
    • Olson, V. G. et al. Role of noradrenergic signaling by the nucleus tractus solitarius in mediating opiate reward. Science 311, 1017-1020 (2006). (Pubitemid 43271731)
    • (2006) Science , vol.311 , Issue.5763 , pp. 1017-1020
    • Olson, V.G.1    Heusner, C.L.2    Bland, R.J.3    During, M.J.4    Weinshenker, D.5    Palmiter, R.D.6
  • 22
    • 0034719355 scopus 로고    scopus 로고
    • Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion
    • DOI 10.1038/35000212
    • Delfs, J. M., Zhu, Y., Druhan, J. P. & Aston-Jones, G. Noradrenaline in the ventral forebrain is critical for opiate withdrawal-induced aversion. Nature 403, 430-434 (2000). (Pubitemid 30073092)
    • (2000) Nature , vol.403 , Issue.6768 , pp. 430-434
    • Delfs, J.M.1    Zhu, Y.2    Druhan, J.P.3    Aston-Jones, G.4
  • 23
    • 33845310372 scopus 로고    scopus 로고
    • Activation in extended amygdala corresponds to altered hedonic processing during protracted morphine withdrawal
    • DOI 10.1016/j.bbr.2006.10.012, PII S0166432806005365
    • Harris, G. C. & Aston-Jones, G. Activation in extended amygdala corresponds to altered hedonic processing during protracted morphine withdrawal. Behav. Brain Res. 176, 251-258 (2007). (Pubitemid 44880087)
    • (2007) Behavioural Brain Research , vol.176 , Issue.2 , pp. 251-258
    • Harris, G.C.1    Aston-Jones, G.2
  • 25
    • 70350247500 scopus 로고    scopus 로고
    • Magnetically induced vagus nerve stimulation and feeding behavior in rats
    • Ziomber, A. et al. Magnetically induced vagus nerve stimulation and feeding behavior in rats. J. Physiol. Pharmacol. 60, 71-77 (2009).
    • (2009) J. Physiol. Pharmacol , vol.60 , pp. 71-77
    • Ziomber, A.1
  • 26
    • 0037072270 scopus 로고    scopus 로고
    • Weight loss associated with vagus nerve stimulation
    • Burneo, J. G., Faught, E., Knowlton, R., Morawetz, R. & Kuzniecky, R. Weight loss associated with vagus nerve stimulation. Neurology 59, 463-464 (2002). (Pubitemid 34857950)
    • (2002) Neurology , vol.59 , Issue.3 , pp. 463-464
    • Burneo, J.G.1    Faught, E.2    Knowlton, R.3    Morawetz, R.4    Kuzniecky, R.5
  • 27
    • 33750293581 scopus 로고    scopus 로고
    • Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry
    • Wang, G. J. et al. Gastric stimulation in obese subjects activates the hippocampus and other regions involved in brain reward circuitry. Proc. Natl Acad. Sci. USA 103, 15641-15645 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , pp. 15641-15645
    • Wang, G.J.1
  • 28
    • 51349115061 scopus 로고    scopus 로고
    • Alcohol abuse and dependence before and after bariatric surgery: A review of the literature and report of a new data set
    • Ertelt, T. W. et al. Alcohol abuse and dependence before and after bariatric surgery: a review of the literature and report of a new data set. Surg. Obes. Relat. Dis. 4, 647-650 (2008).
    • (2008) Surg. Obes. Relat. Dis , vol.4 , pp. 647-650
    • Ertelt, T.W.1
  • 29
    • 45149095307 scopus 로고    scopus 로고
    • Induction of c-Fos and ΔFosB immunoreactivity in rat brain by vagal nerve stimulation
    • DOI 10.1038/sj.npp.1301570, PII 1301570
    • Cunningham, J. T., Mifflin, S. W., Gould, G. G. & Frazer, A. Induction of cFos and δFosB immunoreactivity in rat brain by Vagal nerve stimulation. Neuropsychopharmacology 33, 1884-1895 (2008). (Pubitemid 351832591)
    • (2008) Neuropsychopharmacology , vol.33 , Issue.8 , pp. 1884-1895
    • Cunningham, J.T.1    Mifflin, S.W.2    Gould, G.G.3    Frazer, A.4
  • 30
    • 77953846458 scopus 로고    scopus 로고
    • Induction of FosB/δFosB in the brain stress system-related structures during morphine dependence and withdrawal
    • Nunez, C. et al. Induction of FosB/δFosB in the brain stress system-related structures during morphine dependence and withdrawal. J. Neurochem. 114, 475-487 (2010).
    • (2010) J. Neurochem , vol.114 , pp. 475-487
    • Nunez, C.1
  • 31
    • 0025910356 scopus 로고
    • Alternative splicing of fosB transcripts results in differentially expressed mRNAs encoding functionally antagonistic proteins
    • Mumberg, D., Lucibello, F. C., Schuermann, M. & Muller, R. Alternative splicing of fosB transcripts results in differentially expressed mRNAs encoding functionally antagonistic proteins. Genes Dev. 5, 1212-1223 (1991). (Pubitemid 21906032)
    • (1991) Genes and Development , vol.5 , Issue.7 , pp. 1212-1223
    • Mumberg, D.1    Lucibello, F.C.2    Schuermann, M.3    Muller, R.4
  • 32
    • 0242384719 scopus 로고    scopus 로고
    • Regulation of gene expression and cocaine reward by CREB and ΔFosB
    • DOI 10.1038/nn1143
    • McClung, C. A. & Nestler, E. J. Regulation of gene expression and cocaine reward by CREB and δFosB. Nature Neurosci. 6, 1208-1215 (2003). (Pubitemid 37346042)
    • (2003) Nature Neuroscience , vol.6 , Issue.11 , pp. 1208-1215
    • McClung, C.A.1    Nestler, E.J.2
  • 33
    • 17044427583 scopus 로고    scopus 로고
    • Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: Regulation by cholecystokinin and opioids
    • Appleyard, S. M. et al. Proopiomelanocortin neurons in nucleus tractus solitarius are activated by visceral afferents: regulation by cholecystokinin and opioids. J. Neurosci. 25, 3578-3585 (2005).
    • (2005) J. Neurosci , vol.25 , pp. 3578-3585
    • Appleyard, S.M.1
  • 34
    • 77955417166 scopus 로고    scopus 로고
    • Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity
    • Zhang, Y. et al. Pro-opiomelanocortin gene transfer to the nucleus of the solitary track but not arcuate nucleus ameliorates chronic diet-induced obesity. Neuroscience 169, 1662-1671 (2010).
    • (2010) Neuroscience , vol.169 , pp. 1662-1671
    • Zhang, Y.1
  • 35
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • DOI 10.1152/physrev.00034.2006
    • Holst, J. J. The physiology of glucagon-like peptide 1. Physiol. Rev. 87, 1409-1439 (2007). (Pubitemid 350041474)
    • (2007) Physiological Reviews , vol.87 , Issue.4 , pp. 1409-1439
    • Holst, J.J.1
  • 37
    • 66649088029 scopus 로고    scopus 로고
    • Endogenous hindbrain glucagon-like peptide1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    • Hayes, M. R., Bradley, L. & Grill, H. J. Endogenous hindbrain glucagon-like peptide1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling. Endocrinology 150, 2654-2659 (2009).
    • (2009) Endocrinology , vol.150 , pp. 2654-2659
    • Hayes, M.R.1    Bradley, L.2    Grill, H.J.3
  • 38
    • 79952394105 scopus 로고    scopus 로고
    • Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide1 loss of function
    • Barrera, J. G. et al. Hyperphagia and increased fat accumulation in two models of chronic CNS glucagon-like peptide1 loss of function. J. Neurosci. 31, 3904-3913 (2011).
    • (2011) J. Neurosci , vol.31 , pp. 3904-3913
    • Barrera, J.G.1
  • 39
    • 79952119299 scopus 로고    scopus 로고
    • Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide1 receptor activation
    • Hayes, M. R. et al. Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide1 receptor activation. Cell Metab. 13, 320-330 (2011).
    • (2011) Cell Metab , vol.13 , pp. 320-330
    • Hayes, M.R.1
  • 40
    • 38549111837 scopus 로고    scopus 로고
    • Neural basis of reward and craving - A homeostatic point of view
    • Paulus, M. P. Neural basis of reward and craving-a homeostatic point of view. Dialogues Clin. Neurosci. 9, 379-387 (2007). (Pubitemid 351154627)
    • (2007) Dialogues in Clinical Neuroscience , vol.9 , Issue.4 , pp. 379-387
    • Paulus, M.P.1
  • 41
    • 77951666149 scopus 로고    scopus 로고
    • Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats
    • Johnson, P. M. & Kenny, P. J. Dopamine D2 receptors in addiction-like reward dysfunction and compulsive eating in obese rats. Nature Neurosci. 13, 635-641 (2010).
    • (2010) Nature Neurosci , vol.13 , pp. 635-641
    • Johnson, P.M.1    Kenny, P.J.2
  • 42
    • 38149054861 scopus 로고    scopus 로고
    • Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food
    • Cottone, P., Sabino, V., Steardo, L. & Zorrilla, E. P. Opioid-dependent anticipatory negative contrast and binge-like eating in rats with limited access to highly preferred food. Neuropsychopharmacology 33, 524-535 (2008).
    • (2008) Neuropsychopharmacology , vol.33 , pp. 524-535
    • Cottone, P.1    Sabino, V.2    Steardo, L.3    Zorrilla, E.P.4
  • 43
    • 67949086665 scopus 로고    scopus 로고
    • Insular cortex and consummatory successive negative contrast in the rat
    • Lin, J. Y., Roman, C. & Reilly, S. Insular cortex and consummatory successive negative contrast in the rat. Behav. Neurosci. 123, 810-814 (2009).
    • (2009) Behav. Neurosci , vol.123 , pp. 810-814
    • Lin, J.Y.1    Roman, C.2    Reilly, S.3
  • 44
    • 1842479442 scopus 로고    scopus 로고
    • Excitotoxic Lesions of the Gustatory Thalamus Spare Simultaneous Contrast Effects but Eliminate Anticipatory Negative Contrast: Evidence Against a Memory Deficit
    • DOI 10.1037/0735-7044.118.2.365
    • Reilly, S., Bornovalova, M. & Trifunovic, R. Excitotoxic lesions of the gustatory thalamus spare simultaneous contrast effects but eliminate anticipatory negative contrast: evidence against a memory deficit. Behav. Neurosci. 118, 365-376 (2004). (Pubitemid 38445613)
    • (2004) Behavioral Neuroscience , vol.118 , Issue.2 , pp. 365-376
    • Reilly, S.1    Bornovalova, M.2    Trifunovic, R.3
  • 45
    • 84859438415 scopus 로고    scopus 로고
    • The obese brain: Association of body mass index and insulin sensitivity with resting state network functional connectivity
    • Apr doi:10.1002/hbm.21268
    • Kullmann, S. et al. The obese brain: association of body mass index and insulin sensitivity with resting state network functional connectivity. Hum. Brain Mapp. 21 Apr 2011 (doi:10.1002/hbm.21268).
    • (2011) Hum. Brain Mapp. , vol.21
    • Kullmann, S.1
  • 46
    • 56849092405 scopus 로고    scopus 로고
    • Relation of reward from food intake and anticipated food intake to obesity: A functional magnetic resonance imaging study
    • Stice, E., Spoor, S., Bohon, C., Veldhuizen, M. G. & Small, D. M. Relation of reward from food intake and anticipated food intake to obesity: a functional magnetic resonance imaging study. J. Abnorm. Psychol. 117, 924-935 (2008).
    • (2008) J. Abnorm. Psychol , vol.117 , pp. 924-935
    • Stice, E.1    Spoor, S.2    Bohon, C.3    Veldhuizen, M.G.4    Small, D.M.5
  • 47
    • 79952997807 scopus 로고    scopus 로고
    • Youth at risk for obesity show greater activation of striatal and somatosensory regions to food
    • Stice, E., Yokum, S., Burger, K. S., Epstein, L. H. & Small, D. M. Youth at risk for obesity show greater activation of striatal and somatosensory regions to food. J. Neurosci. 31, 4360-4366 (2011).
    • (2011) J. Neurosci , vol.31 , pp. 4360-4366
    • Stice, E.1    Yokum, S.2    Burger, K.S.3    Epstein, L.H.4    Small, D.M.5
  • 49
    • 33846614921 scopus 로고    scopus 로고
    • Damage to the insula disrupts addiction to cigarette smoking
    • DOI 10.1126/science.1135926
    • Naqvi, N. H., Rudrauf, D., Damasio, H. & Bechara, A. Damage to the insula disrupts addiction to cigarette smoking. Science 315, 531-534 (2007). (Pubitemid 46175760)
    • (2007) Science , vol.315 , Issue.5811 , pp. 531-534
    • Naqvi, N.H.1    Rudrauf, D.2    Damasio, H.3    Bechara, A.4
  • 51
    • 35548982683 scopus 로고    scopus 로고
    • Inactivation of the interoceptive insula disrupts drug craving and malaise induced by lithium
    • DOI 10.1126/science.1145590
    • Contreras, M., Ceric, F. & Torrealba, F. Inactivation of the interoceptive insula disrupts drug craving and malaise induced by lithium. Science 318, 655-658 (2007). (Pubitemid 350014841)
    • (2007) Science , vol.318 , Issue.5850 , pp. 655-658
    • Contreras, M.1    Ceric, F.2    Torrealba, F.3
  • 52
    • 64849084632 scopus 로고    scopus 로고
    • Long-lasting dysregulation of gene expression in corticostriatal circuits after repeated cocaine treatment in adult rats: Effects on zif 268 and homer 1a
    • Unal, C. T., Beverley, J. A., Willuhn, I. & Steiner, H. Long-lasting dysregulation of gene expression in corticostriatal circuits after repeated cocaine treatment in adult rats: effects on zif 268 and homer 1a. Eur. J. Neurosci. 29, 1615-1626 (2009).
    • (2009) Eur. J. Neurosci , vol.29 , pp. 1615-1626
    • Unal, C.T.1    Beverley, J.A.2    Willuhn, I.3    Steiner, H.4
  • 53
    • 34249047082 scopus 로고    scopus 로고
    • Food-associated cues alter forebrain functional connectivity as assessed with immediate early gene and proenkephalin expression
    • Schiltz, C. A., Bremer, Q. Z., Landry, C. F. & Kelley, A. E. Food-associated cues alter forebrain functional connectivity as assessed with immediate early gene and proenkephalin expression. BMC Biol. 5, 16 (2007).
    • (2007) BMC Biol , vol.5 , pp. 16
    • Schiltz, C.A.1    Bremer, Q.Z.2    Landry, C.F.3    Kelley, A.E.4
  • 54
    • 0035873614 scopus 로고    scopus 로고
    • Increased histone acetyltransferase and lysine acetyltransferase activity and biphasic activation of the ERK/RSK cascade in insular cortex during novel taste learning
    • Swank, M. W. & Sweatt, J. D. Increased histone acetyltransferase and lysine acetyltransferase activity and biphasic activation of the ERK/RSK cascade in insular cortex during novel taste learning. J. Neurosci. 21, 3383-3391 (2001). (Pubitemid 32427673)
    • (2001) Journal of Neuroscience , vol.21 , Issue.10 , pp. 3383-3391
    • Swank, M.W.1    Sweatt, J.D.2
  • 56
    • 0032402195 scopus 로고    scopus 로고
    • Specific and differential activation of mitogen-activated protein kinase cascades by unfamiliar taste in the insular cortex of the behaving rat
    • Berman, D. E., Hazvi, S., Rosenblum, K., Seger, R. & Dudai, Y. Specific and differential activation of mitogen-activated protein kinase cascades by unfamiliar taste in the insular cortex of the behaving rat. J. Neurosci. 18, 10037-10044 (1998). (Pubitemid 28543778)
    • (1998) Journal of Neuroscience , vol.18 , Issue.23 , pp. 10037-10044
    • Berman, D.E.1    Hazvi, S.2    Rosenblum, K.3    Seger, R.4    Dudai, Y.5
  • 57
    • 70349574639 scopus 로고    scopus 로고
    • Functional neuroimaging of umami taste: What makes umami pleasant?
    • Rolls, E. T. Functional neuroimaging of umami taste: what makes umami pleasant? Am. J. Clin. Nutr. 90, 804S-813S (2009).
    • (2009) Am. J. Clin. Nutr , vol.90
    • Rolls, E.T.1
  • 58
    • 78650129421 scopus 로고    scopus 로고
    • Thought for food: Imagined consumption reduces actual consumption
    • Morewedge, C. K., Huh, Y. E. & Vosgerau, J. Thought for food: imagined consumption reduces actual consumption. Science 330, 1530-1533 (2010).
    • (2010) Science , vol.330 , pp. 1530-1533
    • Morewedge, C.K.1    Huh, Y.E.2    Vosgerau, J.3
  • 59
    • 77956994788 scopus 로고    scopus 로고
    • Emotion cognition, and mental state representation in amygdala and prefrontal cortex
    • Salzman, C. D. & Fusi, S. Emotion, cognition, and mental state representation in amygdala and prefrontal cortex. Annu. Rev. Neurosci. 33, 173-202 (2010).
    • (2010) Annu. Rev. Neurosci , vol.33 , pp. 173-202
    • Salzman, C.D.1    Fusi, S.2
  • 60
    • 54249084372 scopus 로고    scopus 로고
    • Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: Possible contributing factors
    • Volkow, N. D. et al. Low dopamine striatal D2 receptors are associated with prefrontal metabolism in obese subjects: possible contributing factors. Neuroimage 42, 1537-1543 (2008).
    • (2008) Neuroimage , vol.42 , pp. 1537-1543
    • Volkow, N.D.1
  • 61
    • 34848899271 scopus 로고    scopus 로고
    • Binge eating is associated with right orbitofrontal-insular-striatal atrophy in frontotemporal dementia
    • DOI 10.1212/01.wnl.0000277461.06713.23, PII 0000611420071002000008
    • Woolley, J. D. et al. Binge eating is associated with right orbitofrontalinsularstriatal atrophy in frontotemporal dementia. Neurology 69, 1424-1433 (2007). (Pubitemid 47511464)
    • (2007) Neurology , vol.69 , Issue.14 , pp. 1424-1433
    • Woolley, J.D.1    Gorno-Tempini, M.-L.2    Seeley, W.W.3    Rankin, K.4    Lee, S.S.5    Matthews, B.R.6    Miller, B.L.7
  • 62
    • 79952253896 scopus 로고    scopus 로고
    • Induction of hyperphagia and carbohydrate intake by mu-opioid receptor stimulation in circumscribed regions of frontal cortex
    • Mena, J. D., Sadeghian, K. & Baldo, B. A. Induction of hyperphagia and carbohydrate intake by mu-opioid receptor stimulation in circumscribed regions of frontal cortex. J. Neurosci. 31, 3249-3260 (2011).
    • (2011) J. Neurosci , vol.31 , pp. 3249-3260
    • Mena, J.D.1    Sadeghian, K.2    Baldo, B.A.3
  • 63
    • 64849115465 scopus 로고    scopus 로고
    • Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine
    • Kantak, K. M., Mashhoon, Y., Silverman, D. N., Janes, A. C. & Goodrich, C. M. Role of the orbitofrontal cortex and dorsal striatum in regulating the dose-related effects of self-administered cocaine. Behav. Brain Res. 201, 128-136 (2009).
    • (2009) Behav. Brain Res , vol.201 , pp. 128-136
    • Kantak, K.M.1    Mashhoon, Y.2    Silverman, D.N.3    Janes, A.C.4    Goodrich, C.M.5
  • 64
    • 47549098575 scopus 로고    scopus 로고
    • The role of the orbitofrontal cortex in the pursuit of happiness and more specific rewards
    • Burke, K. A., Franz, T. M., Miller, D. N. & Schoenbaum, G. The role of the orbitofrontal cortex in the pursuit of happiness and more specific rewards. Nature 454, 340-344 (2008).
    • (2008) Nature , vol.454 , pp. 340-344
    • Burke, K.A.1    Franz, T.M.2    Miller, D.N.3    Schoenbaum, G.4
  • 65
    • 0242340265 scopus 로고    scopus 로고
    • Lesions of the Orbitofrontal but not Medial Prefrontal Cortex Disrupt Conditioned Reinforcement in Primates
    • Pears, A., Parkinson, J. A., Hopewell, L., Everitt, B. J. & Roberts, A. C. Lesions of the orbitofrontal but not medial prefrontal cortex disrupt conditioned reinforcement in primates. J. Neurosci. 23, 11189-11201 (2003). (Pubitemid 37548955)
    • (2003) Journal of Neuroscience , vol.23 , Issue.35 , pp. 11189-11201
    • Pears, A.1    Parkinson, J.A.2    Hopewell, L.3    Everitt, B.J.4    Roberts, A.C.5
  • 66
    • 0347091897 scopus 로고    scopus 로고
    • The effects of selective orbitofrontal cortex lesions on the acquisition and performance of cue-controlled cocaine seeking in rats
    • DOI 10.1196/annals.1300.038
    • Hutcheson, D. M. & Everitt, B. J. The effects of selective orbitofrontal cortex lesions on the acquisition and performance of cue-controlled cocaine seeking in rats. Ann. NY Acad. Sci. 1003, 410-411 (2003). (Pubitemid 38083084)
    • (2003) Annals of the New York Academy of Sciences , vol.1003 , pp. 410-411
    • Hutcheson, D.M.1    Everitt, B.J.2
  • 67
    • 49549091368 scopus 로고    scopus 로고
    • Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairments
    • George, O., Mandyam, C. D., Wee, S. & Koob, G. F. Extended access to cocaine self-administration produces long-lasting prefrontal cortex-dependent working memory impairments. Neuropsychopharmacology 33, 2474-2482 (2008).
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2474-2482
    • George, O.1    Mandyam, C.D.2    Wee, S.3    Koob, G.F.4
  • 68
    • 33748128370 scopus 로고    scopus 로고
    • Progression of cellular adaptations in medial prefrontal and orbitofrontal cortex in response to repeated amphetamine
    • DOI 10.1523/JNEUROSCI.0842-06.2006
    • Homayoun, H. & Moghaddam, B. Progression of cellular adaptations in medial prefrontal and orbitofrontal cortex in response to repeated amphetamine. J. Neurosci. 26, 8025-8039 (2006). (Pubitemid 44315127)
    • (2006) Journal of Neuroscience , vol.26 , Issue.31 , pp. 8025-8039
    • Homayoun, H.1    Moghaddam, B.2
  • 69
    • 37849044406 scopus 로고    scopus 로고
    • The role of orbitofrontal cortex in drug addiction: A review of preclinical studies
    • Schoenbaum, G. & Shaham, Y. The role of orbitofrontal cortex in drug addiction: a review of preclinical studies. Biol. Psychiatry 63, 256-262 (2008).
    • (2008) Biol. Psychiatry , vol.63 , pp. 256-262
    • Schoenbaum, G.1    Shaham, Y.2
  • 71
    • 58449084407 scopus 로고    scopus 로고
    • Increased impulsivity during withdrawal from cocaine self-administration: Role for δfosB in the orbitofrontal cortex
    • Winstanley, C. A. et al. Increased impulsivity during withdrawal from cocaine self-administration: role for δFosB in the orbitofrontal cortex. Cereb. Cortex 19, 435-444 (2009).
    • (2009) Cereb. Cortex , vol.19 , pp. 435-444
    • Winstanley, C.A.1
  • 72
    • 0035147463 scopus 로고    scopus 로고
    • Post-ingestive positive controls of ingestive behavior
    • DOI 10.1006/appe.2000.0370
    • Sclafani, A. Post-ingestive positive controls of ingestive behavior. Appetite 36, 79-83 (2001). (Pubitemid 32113531)
    • (2001) Appetite , vol.36 , Issue.1 , pp. 79-83
    • Sclafani, A.1
  • 73
    • 77953495960 scopus 로고    scopus 로고
    • Nutrient selection in the absence of taste receptor signaling
    • Ren, X. et al. Nutrient selection in the absence of taste receptor signaling. J. Neurosci. 30, 8012-8023 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 8012-8023
    • Ren, X.1
  • 74
    • 40849083517 scopus 로고    scopus 로고
    • Food reward in the absence of taste receptor signaling
    • de Araujo, I. E. et al. Food reward in the absence of taste receptor signaling. Neuron 57, 930-941 (2008).
    • (2008) Neuron , vol.57 , pp. 930-941
    • De Araujo, I.E.1
  • 76
    • 60849129122 scopus 로고    scopus 로고
    • Nicotine activates TRPM5-dependent and independent taste pathways
    • Oliveira-Maia, A. J. et al. Nicotine activates TRPM5-dependent and independent taste pathways. Proc. Natl Acad. Sci. USA 106, 1596-1601 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 1596-1601
    • Oliveira-Maia, A.J.1
  • 77
    • 38349026426 scopus 로고    scopus 로고
    • Perception of sweet taste is important for voluntary alcohol consumption in mice
    • Blednov, Y. A. et al. Perception of sweet taste is important for voluntary alcohol consumption in mice. Genes Brain Behav. 7, 1-13 (2008).
    • (2008) Genes Brain Behav , vol.7 , pp. 1-13
    • Blednov, Y.A.1
  • 78
    • 79251598360 scopus 로고    scopus 로고
    • Central dopaminergic circuitry controlling food intake and reward: Implications for the regulation of obesity
    • Wiley Interdiscip
    • Vucetic, Z. & Reyes, T. M. Central dopaminergic circuitry controlling food intake and reward: implications for the regulation of obesity. Wiley Interdiscip. Rev. Syst. Biol. Med. 2, 577-593 (2010).
    • (2010) Rev. Syst. Biol. Med , vol.2 , pp. 577-593
    • Vucetic, Z.1    Reyes, T.M.2
  • 79
    • 23044503827 scopus 로고    scopus 로고
    • D1 dopamine receptors modulate ΔFosB induction in rat striatum after intermittent morphine administration
    • DOI 10.1124/jpet.105.083410
    • Muller, D. L. & Unterwald, E. M. D1 dopamine receptors modulate δFosB induction in rat striatum after intermittent morphine administration. J. Pharmacol. Exp. Ther. 314, 148-154 (2005). (Pubitemid 41058250)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.314 , Issue.1 , pp. 148-154
    • Muller, D.L.1    Unterwald, E.M.2
  • 80
    • 51449118642 scopus 로고    scopus 로고
    • Transcriptional mechanisms of addiction: Role of δfosB
    • Nestler, E. J. Review. Transcriptional mechanisms of addiction: role of δFosB. Phil. Trans. R Soc. Lond. B 363, 3245-3255 (2008).
    • (2008) Phil. Trans. R Soc. Lond B , vol.363 , pp. 3245-3255
    • Nestler, E.J.1
  • 81
    • 68049121848 scopus 로고    scopus 로고
    • Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling
    • Teegarden, S. L., Scott, A. N. & Bale, T. L. Early life exposure to a high fat diet promotes long-term changes in dietary preferences and central reward signaling. Neuroscience 162, 924-932 (2009).
    • (2009) Neuroscience , vol.162 , pp. 924-932
    • Teegarden, S.L.1    Scott, A.N.2    Bale, T.L.3
  • 82
    • 79952489151 scopus 로고    scopus 로고
    • Snacking causes long term attenuation of HPA axis stress responses and enhancement of brain FosB/δFosB expression in rats
    • Christiansen, A. M., Dekloet, A. D., Ulrich-Lai, Y. M. & Herman, J. P. "Snacking" causes long term attenuation of HPA axis stress responses and enhancement of brain FosB/δFosB expression in rats. Physiol. Behav. 103, 111-116 (2011).
    • (2011) Physiol. Behav , vol.103 , pp. 111-116
    • Christiansen, A.M.1    Dekloet, A.D.2    Ulrich-Lai, Y.M.3    Herman, J.P.4
  • 83
    • 55249122524 scopus 로고    scopus 로고
    • The influence of δfosB in the nucleus accumbens on natural reward-related behavior
    • Wallace, D. L. et al. The influence of δFosB in the nucleus accumbens on natural reward-related behavior. J. Neurosci. 28, 10272-10277 (2008).
    • (2008) J. Neurosci , vol.28 , pp. 10272-10277
    • Wallace, D.L.1
  • 84
    • 34047263811 scopus 로고    scopus 로고
    • Decreases in dietary preference produce increased emotionality and risk for dietary relapse
    • DOI 10.1016/j.biopsych.2006.09.032, PII S0006322306012200
    • Teegarden, S. L. & Bale, T. L. Decreases in dietary preference produce increased emotionality and risk for dietary relapse. Biol. Psychiatry 61, 1021-1029 (2007). (Pubitemid 46551977)
    • (2007) Biological Psychiatry , vol.61 , Issue.9 , pp. 1021-1029
    • Teegarden, S.L.1    Bale, T.L.2
  • 85
    • 41549163200 scopus 로고    scopus 로고
    • Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and δfosB expression in the nucleus accumbens of the rat
    • Stamp, J. A., Mashoodh, R., van Kampen, J. M. & Robertson, H. A. Food restriction enhances peak corticosterone levels, cocaine-induced locomotor activity, and δFosB expression in the nucleus accumbens of the rat. Brain Res. 1204, 94-101 (2008).
    • (2008) Brain Res , vol.1204 , pp. 94-101
    • Stamp, J.A.1    Mashoodh, R.2    Van Kampen, J.M.3    Robertson, H.A.4
  • 87
    • 0037444572 scopus 로고    scopus 로고
    • Striatal cell type-specific overexpression of ΔFosB enhances incentive for cocaine
    • Colby, C. R., Whisler, K., Steffen, C., Nestler, E. J. & Self, D. W. Striatal cell type-specific overexpression of δFosB enhances incentive for cocaine. J. Neurosci. 23, 2488-2493 (2003). (Pubitemid 36368938)
    • (2003) Journal of Neuroscience , vol.23 , Issue.6 , pp. 2488-2493
    • Colby, C.R.1    Whisler, K.2    Steffen, C.3    Nestler, E.J.4    Self, D.W.5
  • 88
    • 55349106519 scopus 로고    scopus 로고
    • Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet
    • Teegarden, S. L., Nestler, E. J. & Bale, T. L. Delta FosB-mediated alterations in dopamine signaling are normalized by a palatable high-fat diet. Biol. Psychiatry 64, 941-950 (2008).
    • (2008) Biol. Psychiatry , vol.64 , pp. 941-950
    • Teegarden, S.L.1    Nestler, E.J.2    Bale, T.L.3
  • 93
    • 0035853836 scopus 로고    scopus 로고
    • A kinase to dampen the effects of cocaine?
    • DOI 10.1126/science.1060028
    • Gupta, A. & Tsai, L. H. Neuroscience. A kinase to dampen the effects of cocaine? Science 292, 236-237 (2001). (Pubitemid 32295374)
    • (2001) Science , vol.292 , Issue.5515 , pp. 236-237
    • Gupta, A.1    Tsa, L.-H.2
  • 95
    • 0022294711 scopus 로고
    • Immunohistochemical localization of a melanin concentrating hormone-like peptide in the rat brain
    • DOI 10.1016/0361-9230(85)90213-8
    • Skofitsch, G., Jacobowitz, D. M. & Zamir, N. Immunohistochemical localization of a melanin concentrating hormone-like peptide in the rat brain. Brain Res. Bull. 15, 635-649 (1985). (Pubitemid 16149275)
    • (1985) Brain Research Bulletin , vol.15 , Issue.6 , pp. 635-649
    • Skofitsch, G.1    Jacobowitz, D.M.2    Zamir, N.3
  • 100
    • 77953766300 scopus 로고    scopus 로고
    • Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone
    • Sears, R. M. et al. Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone. J. Neurosci. 30, 8263-8273 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 8263-8273
    • Sears, R.M.1
  • 101
    • 66149147508 scopus 로고    scopus 로고
    • The melanin-concentrating hormone system modulates cocaine reward
    • Chung, S. et al. The melanin-concentrating hormone system modulates cocaine reward. Proc. Natl Acad. Sci. USA 106, 6772-6777 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 6772-6777
    • Chung, S.1
  • 102
    • 35348824334 scopus 로고    scopus 로고
    • Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens
    • DOI 10.1523/JNEUROSCI.3542-07.2007
    • Zheng, H., Patterson, L. M. & Berthoud, H. R. Orexin signaling in the ventral tegmental area is required for high-fat appetite induced by opioid stimulation of the nucleus accumbens. J. Neurosci. 27, 11075-11082 (2007). (Pubitemid 47574162)
    • (2007) Journal of Neuroscience , vol.27 , Issue.41 , pp. 11075-11082
    • Zheng, H.1    Patterson, L.M.2    Berthoud, H.-R.3
  • 103
    • 0035800233 scopus 로고    scopus 로고
    • 2+ signaling in dopamine neurons of the ventral tegmental area
    • Uramura, K. et al. Orexina activates phospholipase C and protein kinase Cmediated Ca2+ signaling in dopamine neurons of the ventral tegmental area. Neuroreport 12, 1885-1889 (2001). (Pubitemid 32553702)
    • (2001) NeuroReport , vol.12 , Issue.9 , pp. 1885-1889
    • Uramura, K.1    Funahashi, H.2    Muroya, S.3    Shioda, S.4    Takigawa, M.5    Yada, T.6
  • 104
    • 77953710614 scopus 로고    scopus 로고
    • Role of orexin/hypocretin in reward-seeking and addiction: Implications for obesity
    • Cason, A. M. et al. Role of orexin/hypocretin in reward-seeking and addiction: implications for obesity. Physiol. Behav. 100, 419-428 (2010).
    • (2010) Physiol. Behav , vol.100 , pp. 419-428
    • Cason, A.M.1
  • 105
  • 106
    • 34548675339 scopus 로고    scopus 로고
    • Leptin regulates striatal regions and human eating behavior
    • Farooqi, I. S. et al. Leptin regulates striatal regions and human eating behavior. Science 317, 1355 (2007).
    • (2007) Science , vol.317 , pp. 1355
    • Farooqi, I.S.1
  • 107
    • 0037458468 scopus 로고    scopus 로고
    • Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat
    • DOI 10.1016/S0006-8993(02)04087-8
    • Figlewicz, D. P., Evans, S. B., Murphy, J., Hoen, M. & Baskin, D. G. Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat. Brain Res. 964, 107-115 (2003). (Pubitemid 36165075)
    • (2003) Brain Research , vol.964 , Issue.1 , pp. 107-115
    • Figlewicz, D.P.1    Evans, S.B.2    Murphy, J.3    Hoen, M.4    Baskin, D.G.5
  • 110
    • 67650088267 scopus 로고    scopus 로고
    • The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak2 signaling
    • Morton, G. J., Blevins, J. E., Kim, F., Matsen, M. & Figlewicz, D. P. The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak2 signaling. Am. J. Physiol. Endocrinol. Metab. 297, e202-e210 (2009).
    • (2009) Am. J. Physiol. Endocrinol. Metab , vol.297
    • Morton, G.J.1    Blevins, J.E.2    Kim, F.3    Matsen, M.4    Figlewicz, D.P.5
  • 111
    • 79952706915 scopus 로고    scopus 로고
    • Effects of insulin and leptin in the ventral tegmental area and arcuate hypothalamic nucleus on food intake and brain reward function in female rats
    • Bruijnzeel, A. W., Corrie, L. W., Rogers, J. A. & Yamada, H. Effects of insulin and leptin in the ventral tegmental area and arcuate hypothalamic nucleus on food intake and brain reward function in female rats. Behav. Brain Res. 219, 254-264 (2011).
    • (2011) Behav. Brain Res , vol.219 , pp. 254-264
    • Bruijnzeel, A.W.1    Corrie, L.W.2    Rogers, J.A.3    Yamada, H.4
  • 112
    • 79952572475 scopus 로고    scopus 로고
    • Leptin regulates energy balance and motivation through action at distinct neural circuits
    • Davis, J. F. et al. Leptin regulates energy balance and motivation through action at distinct neural circuits. Biol. Psychiatry 69, 668-674 (2011).
    • (2011) Biol. Psychiatry , vol.69 , pp. 668-674
    • Davis, J.F.1
  • 114
    • 0029807321 scopus 로고    scopus 로고
    • Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system
    • Berhow, M. T., Hiroi, N., Kobierski, L. A., Hyman, S. E. & Nestler, E. J. Influence of cocaine on the JAK-STAT pathway in the mesolimbic dopamine system. J. Neurosci. 16, 8019-8026 (1996). (Pubitemid 26405063)
    • (1996) Journal of Neuroscience , vol.16 , Issue.24 , pp. 8019-8026
    • Berhow, M.T.1    Hiroi, N.2    Kobierski, L.A.3    Hyman, S.E.4    Nestler, E.J.5
  • 115
    • 0021326129 scopus 로고
    • Characterization and regulation of insulin receptors in rat brain
    • Zahniser, N. R., Goens, M. B., Hanaway, P. J. & Vinych, J. V. Characterization and regulation of insulin receptors in rat brain. J. Neurochem. 42, 1354-1362 (1984). (Pubitemid 14137620)
    • (1984) Journal of Neurochemistry , vol.42 , Issue.5 , pp. 1354-1362
    • Zahniser, N.R.1    Goens, M.B.2    Hanaway, P.J.3    Vinych, J.V.4
  • 117
    • 79958026765 scopus 로고    scopus 로고
    • Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis
    • Konner, A. C. et al. Role for insulin signaling in catecholaminergic neurons in control of energy homeostasis. Cell Metab. 13, 720-728 (2011).
    • (2011) Cell Metab , vol.13 , pp. 720-728
    • Konner, A.C.1
  • 118
    • 0030607721 scopus 로고    scopus 로고
    • Effects of diabetes on methamphetamine-induced place preference in mice
    • DOI 10.1016/S0014-2999(96)00804-7, PII S0014299996008047
    • Kamei, J. & Ohsawa, M. Effects of diabetes on methamphetamine-induced place preference in mice. Eur. J. Pharmacol. 318, 251-256 (1996). (Pubitemid 27046265)
    • (1996) European Journal of Pharmacology , vol.318 , Issue.2-3 , pp. 251-256
    • Kamei, J.1    Ohsawa, M.2
  • 120
    • 77249134520 scopus 로고    scopus 로고
    • Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system
    • Cordeira, J. W., Frank, L., Sena-Esteves, M., Pothos, E. N. & Rios, M. Brain-derived neurotrophic factor regulates hedonic feeding by acting on the mesolimbic dopamine system. J. Neurosci. 30, 2533-2541 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 2533-2541
    • Cordeira, J.W.1    Frank, L.2    Sena-Esteves, M.3    Pothos, E.N.4    Rios, M.5
  • 121
    • 0344305487 scopus 로고    scopus 로고
    • Basal and feeding-evoked dopamine release in the rat nucleus accumbens is depressed by leptin
    • DOI 10.1016/j.ejphar.2003.09.047
    • Krugel, U., Schraft, T., Kittner, H., Kiess, W. & Illes, P. Basal and feeding-evoked dopamine release in the rat nucleus accumbens is depressed by leptin. Eur. J. Pharmacol. 482, 185-187 (2003). (Pubitemid 37505943)
    • (2003) European Journal of Pharmacology , vol.482 , Issue.1-3 , pp. 185-187
    • Krugel, U.1    Schraft, T.2    Kittner, H.3    Kiess, W.4    Illes, P.5
  • 122
    • 34347325204 scopus 로고    scopus 로고
    • Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice
    • DOI 10.1523/JNEUROSCI.1235-07.2007
    • Roseberry, A. G., Painter, T., Mark, G. P. & Williams, J. T. Decreased vesicular somatodendritic dopamine stores in leptin-deficient mice. J. Neurosci. 27, 7021-7027 (2007). (Pubitemid 47015890)
    • (2007) Journal of Neuroscience , vol.27 , Issue.26 , pp. 7021-7027
    • Roseberry, A.G.1    Painter, T.2    Mark, G.P.3    Williams, J.T.4
  • 123
    • 54149103333 scopus 로고    scopus 로고
    • Insulin receptor substrate2 in the ventral tegmental area regulates behavioral responses to cocaine
    • Iniguez, S. D. et al. Insulin receptor substrate2 in the ventral tegmental area regulates behavioral responses to cocaine. Behav. Neurosci. 122, 1172-1177 (2008).
    • (2008) Behav. Neurosci , vol.122 , pp. 1172-1177
    • Iniguez, S.D.1
  • 125
    • 79251552268 scopus 로고    scopus 로고
    • Insulin modulates cocaine-sensitive monoamine transporter function and impulsive behavior
    • Schoffelmeer, A. N. et al. Insulin modulates cocaine-sensitive monoamine transporter function and impulsive behavior. J. Neurosci. 31, 1284-1291 (2011).
    • (2011) J. Neurosci , vol.31 , pp. 1284-1291
    • Schoffelmeer, A.N.1
  • 126
    • 45549086741 scopus 로고    scopus 로고
    • High impulsivity predicts the switch to compulsive cocaine-taking
    • DOI 10.1126/science.1158136
    • Belin, D., Mar., A. C., Dalley, J. W., Robbins, T. W. & Everitt, B. J. High impulsivity predicts the switch to compulsive cocaine-taking. Science 320, 1352-1355 (2008). (Pubitemid 351929473)
    • (2008) Science , vol.320 , Issue.5881 , pp. 1352-1355
    • Belin, D.1    Mar, A.C.2    Dalley, J.W.3    Robbins, T.W.4    Everitt, B.J.5
  • 127
    • 36849004400 scopus 로고    scopus 로고
    • The neurobiology and genetics of impulse control disorders: Relationships to drug addictions
    • DOI 10.1016/j.bcp.2007.06.043, PII S0006295207004236, Addiction
    • Brewer, J. A. & Potenza, M. N. The neurobiology and genetics of impulse control disorders: relationships to drug addictions. Biochem. Pharmacol. 75, 63-75 (2008). (Pubitemid 350235392)
    • (2008) Biochemical Pharmacology , vol.75 , Issue.1 , pp. 63-75
    • Brewer, J.A.1    Potenza, M.N.2
  • 128
    • 77957193584 scopus 로고    scopus 로고
    • Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats
    • Wang, X. et al. Nucleus accumbens core mammalian target of rapamycin signaling pathway is critical for cue-induced reinstatement of cocaine seeking in rats. J. Neurosci. 30, 12632-12641 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 12632-12641
    • Wang, X.1
  • 129
    • 3242724040 scopus 로고    scopus 로고
    • Activation of the phosphoinositide 3-kinase-Akt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression
    • DOI 10.1523/JNEUROSCI.0995-04.2004
    • Hou, L. & Klann, E. Activation of the phosphoinositide 3kinaseAkt-mammalian target of rapamycin signaling pathway is required for metabotropic glutamate receptor-dependent long-term depression. J. Neurosci. 24, 6352-6361 (2004). (Pubitemid 38944226)
    • (2004) Journal of Neuroscience , vol.24 , Issue.28 , pp. 6352-6361
    • Hou, L.1    Klann, E.2
  • 130
    • 77954062541 scopus 로고    scopus 로고
    • Transition to addiction is associated with a persistent impairment in synaptic plasticity
    • Kasanetz, F. et al. Transition to addiction is associated with a persistent impairment in synaptic plasticity. Science 328, 1709-1712 (2010).
    • (2010) Science , vol.328 , pp. 1709-1712
    • Kasanetz, F.1
  • 131
    • 80052967830 scopus 로고    scopus 로고
    • Down-regulated striatal gene expression for synaptic plasticity- associated proteins in addiction and relapse vulnerable animals
    • Brown, A. L., Flynn, J. R., Smith, D. W. & Dayas, C. V. Down-regulated striatal gene expression for synaptic plasticity-associated proteins in addiction and relapse vulnerable animals. Int. J. Neuropsychopharmacol. 14, 1099-1110 (2010).
    • (2010) Int. J. Neuropsychopharmacol , vol.14 , pp. 1099-1110
    • Brown, A.L.1    Flynn, J.R.2    Smith, D.W.3    Dayas, C.V.4
  • 132
    • 79951979686 scopus 로고    scopus 로고
    • Nutritional omega3 deficiency abolishes endocannabinoid-mediated neuronal functions
    • Lafourcade, M. et al. Nutritional omega3 deficiency abolishes endocannabinoid-mediated neuronal functions. Nature Neurosci. 14, 345-350 (2011).
    • (2011) Nature Neurosci , vol.14 , pp. 345-350
    • Lafourcade, M.1
  • 133
    • 79956210669 scopus 로고    scopus 로고
    • Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission
    • Jiao, S. & Li, Z. Nonapoptotic function of BAD and BAX in long-term depression of synaptic transmission. Neuron 70, 758-772 (2011).
    • (2011) Neuron , vol.70 , pp. 758-772
    • Jiao, S.1    Li, Z.2
  • 134
    • 77953271477 scopus 로고    scopus 로고
    • Caspase3 activation via mitochondria is required for long-term depression and AMPA receptor internalization
    • Li, Z. et al. Caspase3 activation via mitochondria is required for long-term depression and AMPA receptor internalization. Cell 141, 859-871 (2010).
    • (2010) Cell , vol.141 , pp. 859-871
    • Li, Z.1
  • 135
    • 79955485064 scopus 로고    scopus 로고
    • Caspase signalling controls microglia activation and neurotoxicity
    • Burguillos, M. A. et al. Caspase signalling controls microglia activation and neurotoxicity. Nature 472, 319-324 (2011).
    • (2011) Nature , vol.472 , pp. 319-324
    • Burguillos, M.A.1
  • 136
    • 48049101604 scopus 로고    scopus 로고
    • Activation of striatal inflammatory mediators and caspase3 is central to haloperidol-induced orofacial dyskinesia
    • Bishnoi, M., Chopra, K. & Kulkarni, S. K. Activation of striatal inflammatory mediators and caspase3 is central to haloperidol-induced orofacial dyskinesia. Eur. J. Pharmacol. 590, 241-245 (2008).
    • (2008) Eur. J. Pharmacol , vol.590 , pp. 241-245
    • Bishnoi, M.1    Chopra, K.2    Kulkarni, S.K.3
  • 137
    • 33845866857 scopus 로고    scopus 로고
    • Inflammation and metabolic disorders
    • DOI 10.1038/nature05485, PII NATURE05485
    • Hotamisligil, G. S. Inflammation and metabolic disorders. Nature 444, 860-867 (2006). (Pubitemid 46024993)
    • (2006) Nature , vol.444 , Issue.7121 , pp. 860-867
    • Hotamisligil, G.S.1
  • 138
    • 52949096557 scopus 로고    scopus 로고
    • Hypothalamic IKKκ/NF-κB and ER stress link overnutrition to energy imbalance and obesity
    • Zhang, X. et al. Hypothalamic IKKκ/NF-κB and ER stress link overnutrition to energy imbalance and obesity. Cell 135, 61-73 (2008).
    • (2008) Cell , vol.135 , pp. 61-73
    • Zhang, X.1
  • 139
    • 70349484212 scopus 로고    scopus 로고
    • MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
    • Kleinridders, A. et al. MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity. Cell Metab. 10, 249-259 (2009).
    • (2009) Cell Metab , vol.10 , pp. 249-259
    • Kleinridders, A.1
  • 140
    • 79960117277 scopus 로고    scopus 로고
    • Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NFκB
    • Purkayastha, S., Zhang, G. & Cai, D. Uncoupling the mechanisms of obesity and hypertension by targeting hypothalamic IKK-β and NFκB. Nature medicine 17, 883-887 (2011).
    • (2011) Nature Medicine , vol.17 , pp. 883-887
    • Purkayastha, S.1    Zhang, G.2    Cai, D.3
  • 141
    • 79151485914 scopus 로고    scopus 로고
    • Obesity-mediated inflammation may damage the brain circuit that regulates food intake
    • Cazettes, F., Cohen, J. I., Yau, P. L., Talbot, H. & Convit, A. Obesity-mediated inflammation may damage the brain circuit that regulates food intake. Brain Res. 1373, 101-109 (2011).
    • (2011) Brain Res , vol.1373 , pp. 101-109
    • Cazettes, F.1    Cohen, J.I.2    Yau, P.L.3    Talbot, H.4    Convit, A.5
  • 142
    • 63849227432 scopus 로고    scopus 로고
    • Nuclear factor κ B signaling regulates neuronal morphology and cocaine reward
    • Russo, S. J. et al. Nuclear factor κ B signaling regulates neuronal morphology and cocaine reward. J. Neurosci. 29, 3529-3537 (2009).
    • (2009) J. Neurosci , vol.29 , pp. 3529-3537
    • Russo, S.J.1
  • 144
    • 79955729616 scopus 로고    scopus 로고
    • Induction of innate immune genes in brain create the neurobiology of addiction
    • Crews, F. T., Zou, J. & Qin, L. Induction of innate immune genes in brain create the neurobiology of addiction. Brain Behav. Immun. 25, S4-S12 (2011).
    • (2011) Brain Behav. Immun , vol.25
    • Crews, F.T.1    Zou, J.2    Qin, L.3
  • 146
    • 77956644726 scopus 로고    scopus 로고
    • SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity
    • Ramadori, G. et al. SIRT1 deacetylase in POMC neurons is required for homeostatic defenses against diet-induced obesity. Cell Metab. 12, 78-87 (2010).
    • (2010) Cell Metab , vol.12 , pp. 78-87
    • Ramadori, G.1
  • 147
    • 65549142573 scopus 로고    scopus 로고
    • Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins
    • Renthal, W. et al. Genome-wide analysis of chromatin regulation by cocaine reveals a role for sirtuins. Neuron 62, 335-348 (2009).
    • (2009) Neuron , vol.62 , pp. 335-348
    • Renthal, W.1
  • 150
    • 79952460585 scopus 로고    scopus 로고
    • Gene regulation through RNA editing
    • Maas, S. Gene regulation through RNA editing. Discov. Med. 10, 379-386 (2010).
    • (2010) Discov. Med , vol.10 , pp. 379-386
    • Maas, S.1
  • 152
    • 30844442607 scopus 로고    scopus 로고
    • The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C
    • DOI 10.1126/science.1118265
    • Kishore, S. & Stamm, S. The snoRNA HBII52 regulates alternative splicing of the serotonin receptor 2C. Science 311, 230-232 (2006). (Pubitemid 43108188)
    • (2006) Science , vol.311 , Issue.5758 , pp. 230-232
    • Kishore, S.1    Stamm, S.2
  • 154
    • 77954510708 scopus 로고    scopus 로고
    • Striatal microRNA controls cocaine intake through CREB signalling
    • Hollander, J. A. et al. Striatal microRNA controls cocaine intake through CREB signalling. Nature 466, 197-202 (2010).
    • (2010) Nature , vol.466 , pp. 197-202
    • Hollander, J.A.1
  • 155
    • 79955692835 scopus 로고    scopus 로고
    • A role for central nervous system PPAR-γ in the regulation of energy balance
    • Ryan, K. K. et al. A role for central nervous system PPAR-γ in the regulation of energy balance. Nature Med. 17, 623-626 (2011).
    • (2011) Nature Med , vol.17 , pp. 623-626
    • Ryan, K.K.1
  • 156
    • 79955694276 scopus 로고    scopus 로고
    • Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones
    • Lu, M. et al. Brain PPAR-γ promotes obesity and is required for the insulin-sensitizing effect of thiazolidinediones. Nature Med. 17, 618-622 (2011).
    • (2011) Nature Med , vol.17 , pp. 618-622
    • Lu, M.1
  • 157
    • 79952572942 scopus 로고    scopus 로고
    • Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking
    • Stopponi, S. et al. Activation of nuclear PPARγ receptors by the antidiabetic agent pioglitazone suppresses alcohol drinking and relapse to alcohol seeking. Biol. Psychiatry 69, 642-649 (2011).
    • (2011) Biol. Psychiatry , vol.69 , pp. 642-649
    • Stopponi, S.1
  • 158
    • 74849125320 scopus 로고    scopus 로고
    • Reduction of adult hippocampal neurogenesis confers vulnerability in an animal model of cocaine addiction
    • Noonan, M. A., Bulin, S. E., Fuller, D. C. & Eisch, A. J. Reduction of adult hippocampal neurogenesis confers vulnerability in an animal model of cocaine addiction. J. Neurosci. 30, 304-315 (2010).
    • (2010) J. Neurosci , vol.30 , pp. 304-315
    • Noonan, M.A.1    Bulin, S.E.2    Fuller, D.C.3    Eisch, A.J.4
  • 160
    • 79958702575 scopus 로고    scopus 로고
    • Nicotine decreases food intake through activation of POMC neurons
    • Mineur, Y. S. et al. Nicotine decreases food intake through activation of POMC neurons. Science 332, 1330-1332 (2011).
    • (2011) Science , vol.332 , pp. 1330-1332
    • Mineur, Y.S.1
  • 161
    • 78649459183 scopus 로고    scopus 로고
    • Overexpression of Fto leads to increased food intake and results in obesity
    • Church, C. et al. Overexpression of Fto leads to increased food intake and results in obesity. Nature Genet. 42, 1086-1092 (2010).
    • (2010) Nature Genet , vol.42 , pp. 1086-1092
    • Church, C.1
  • 162
    • 77957258099 scopus 로고    scopus 로고
    • Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes
    • Vucetic, Z., Kimmel, J., Totoki, K., Hollenbeck, E. & Reyes, T. M. Maternal high-fat diet alters methylation and gene expression of dopamine and opioid-related genes. Endocrinology 151, 4756-4764 (2010).
    • (2010) Endocrinology , vol.151 , pp. 4756-4764
    • Vucetic, Z.1    Kimmel, J.2    Totoki, K.3    Hollenbeck, E.4    Reyes, T.M.5
  • 163
    • 79954573165 scopus 로고    scopus 로고
    • Chronic high-fat diet drives postnatal epigenetic regulation of mu-opioid receptor in the brain
    • Vucetic, Z., Kimmel, J. & Reyes, T. M. Chronic high-fat diet drives postnatal epigenetic regulation of mu-opioid receptor in the brain. Neuropsychopharmacology 36, 1199-1206 (2011).
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1199-1206
    • Vucetic, Z.1    Kimmel, J.2    Reyes, T.M.3
  • 164
    • 79956301666 scopus 로고    scopus 로고
    • Maternal high-fat diet effects on third-generation female body size via the paternal lineage
    • Dunn, G. A. & Bale, T. L. Maternal high-fat diet effects on third-generation female body size via the paternal lineage. Endocrinology 152, 2228-2236 (2011).
    • (2011) Endocrinology , vol.152 , pp. 2228-2236
    • Dunn, G.A.1    Bale, T.L.2
  • 166
    • 73949112453 scopus 로고    scopus 로고
    • CRF system recruitment mediates dark side of compulsive eating
    • Cottone, P. et al. CRF system recruitment mediates dark side of compulsive eating. Proc. Natl Acad. Sci. USA 106, 20016-20020 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 20016-20020
    • Cottone, P.1
  • 167
    • 75149143341 scopus 로고    scopus 로고
    • The role of CRF and CRF-related peptides in the dark side of addiction
    • Koob, G. F. The role of CRF and CRF-related peptides in the dark side of addiction. Brain Res. 1314, 3-14 (2010).
    • (2010) Brain Res , vol.1314 , pp. 3-14
    • Koob, G.F.1
  • 168
    • 0029978118 scopus 로고    scopus 로고
    • Effects of high- and low-energy meals on hunger, physiological processes and reactions to emotional stress
    • Macht, M. Effects of high- and low-energy meals on hunger, physiological processes and reactions to emotional stress. Appetite 26, 71-88 (1996).
    • (1996) Appetite , vol.26 , pp. 71-88
    • MacHt, M.1
  • 169
    • 79952640155 scopus 로고    scopus 로고
    • Motivation for palatable food despite consequences in an animal model of binge eating
    • Oswald, K. D., Murdaugh, D. L., King, V. L. & Boggiano, M. M. Motivation for palatable food despite consequences in an animal model of binge eating. Int. J. Eat Disord. 44, 203-211 (2010).
    • (2010) Int. J. Eat Disord. , vol.44 , pp. 203-211
    • Oswald, K.D.1    Murdaugh, D.L.2    King, V.L.3    Boggiano, M.M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.