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Volumn 13, Issue 3, 2011, Pages 320-330

Intracellular signals mediating the food intake-suppressive effects of hindbrain glucagon-like peptide-1 receptor activation

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE RIBOSIDE; CYCLIC AMP DEPENDENT PROTEIN KINASE; EXENDIN 4; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; MITOGEN ACTIVATED PROTEIN KINASE; UO 126;

EID: 79952119299     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2011.02.001     Document Type: Article
Times cited : (181)

References (56)
  • 2
    • 19344375318 scopus 로고    scopus 로고
    • Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats
    • P.K. Chelikani, A.C. Haver, and R.D. Reidelberger Intravenous infusion of glucagon-like peptide-1 potently inhibits food intake, sham feeding, and gastric emptying in rats Am. J. Physiol. Regul. Integr. Comp. Physiol. 288 2005 R1695 R1706
    • (2005) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.288
    • Chelikani, P.K.1    Haver, A.C.2    Reidelberger, R.D.3
  • 3
    • 0142026885 scopus 로고    scopus 로고
    • Melanocortin receptor signaling through mitogen-activated protein kinase in vitro and in rat hypothalamus
    • DOI 10.1016/S0006-8993(03)03162-7
    • D. Daniels, C.S. Patten, J.D. Roth, D.K. Yee, and S.J. Fluharty Melanocortin receptor signaling through mitogen-activated protein kinase in vitro and in rat hypothalamus Brain Res. 986 2003 1 11 (Pubitemid 37272095)
    • (2003) Brain Research , vol.986 , Issue.1-2 , pp. 1-11
    • Daniels, D.1    Patten, C.S.2    Roth, J.D.3    Yee, D.K.4    Fluharty, S.J.5
  • 4
    • 27844583473 scopus 로고    scopus 로고
    • Divergent behavioral roles of angiotensin receptor intracellular signaling cascades
    • DOI 10.1210/en.2005-0774
    • D. Daniels, D.K. Yee, L.F. Faulconbridge, and S.J. Fluharty Divergent behavioral roles of angiotensin receptor intracellular signaling cascades Endocrinology 146 2005 5552 5560 (Pubitemid 41655947)
    • (2005) Endocrinology , vol.146 , Issue.12 , pp. 5552-5560
    • Daniels, D.1    Yee, D.K.2    Faulconbridge, L.F.3    Fluharty, S.J.4
  • 5
    • 0038584871 scopus 로고    scopus 로고
    • Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression
    • DOI 10.1042/BJ20021812
    • G. da Silva Xavier, I. Leclerc, A. Varadi, T. Tsuboi, S.K. Moule, and G.A. Rutter Role for AMP-activated protein kinase in glucose-stimulated insulin secretion and preproinsulin gene expression Biochem. J. 371 2003 761 774 (Pubitemid 36578875)
    • (2003) Biochemical Journal , vol.371 , Issue.3 , pp. 761-774
    • Da Silva Xavier, G.1    Leclerc, I.2    Varadi, A.3    Tsuboi, T.4    Moule, S.K.5    Rutter, G.A.6
  • 6
    • 0025365945 scopus 로고
    • Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases i and II with analogs of adenosine 3′,5′-cyclic phosphorothioates
    • W.R. Dostmann, S.S. Taylor, H.G. Genieser, B. Jastorff, S.O. Doskeland, and D. Ogreid Probing the cyclic nucleotide binding sites of cAMP-dependent protein kinases I and II with analogs of adenosine 3′,5′-cyclic phosphorothioates J. Biol. Chem. 265 1990 10484 10491
    • (1990) J. Biol. Chem. , vol.265 , pp. 10484-10491
    • Dostmann, W.R.1    Taylor, S.S.2    Genieser, H.G.3    Jastorff, B.4    Doskeland, S.O.5    Ogreid, D.6
  • 8
    • 0028867442 scopus 로고
    • Distribution of GLP-1 binding sites in the rat brain: Evidence that exendin-4 is a ligand of brain GLP-1 binding sites
    • R. Goke, P.J. Larsen, J.D. Mikkelsen, and S.P. Sheikh Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites Eur. J. Neurosci. 7 1995 2294 2300
    • (1995) Eur. J. Neurosci. , vol.7 , pp. 2294-2300
    • Goke, R.1    Larsen, P.J.2    Mikkelsen, J.D.3    Sheikh, S.P.4
  • 9
    • 0037073717 scopus 로고    scopus 로고
    • 2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic β-cells
    • DOI 10.1074/jbc.M209165200
    • E. Gomez, C. Pritchard, and T.P. Herbert cAMP-dependent protein kinase and Ca2+ influx through L-type voltage-gated calcium channels mediate Raf-independent activation of extracellular regulated kinase in response to glucagon-like peptide-1 in pancreatic beta-cells J. Biol. Chem. 277 2002 48146 48151 (Pubitemid 35470763)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.50 , pp. 48146-48151
    • Gomez, E.1    Pritchard, C.2    Herbert, T.P.3
  • 12
    • 33746092906 scopus 로고    scopus 로고
    • Dorsal hindbrain 5-HT3 receptors participate in control of meal size and mediate CCK-induced satiation
    • DOI 10.1016/j.brainres.2006.05.058, PII S0006899306015526
    • M.R. Hayes, and M. Covasa Dorsal hindbrain 5-HT3 receptors participate in control of meal size and mediate CCK-induced satiation Brain Res. 1103 2006 99 107 (Pubitemid 44080123)
    • (2006) Brain Research , vol.1103 , Issue.1 , pp. 99-107
    • Hayes, M.R.1    Covasa, M.2
  • 13
    • 66149185377 scopus 로고    scopus 로고
    • Dorsal hindbrain AMP-Kinase as an intracellular mediator of energy balance
    • M.R. Hayes, K.P. Skibicka, K.K. Bence, and H.J. Grill Dorsal hindbrain AMP-Kinase as an intracellular mediator of energy balance Endocrinology 150 2008 2175 2182
    • (2008) Endocrinology , vol.150 , pp. 2175-2182
    • Hayes, M.R.1    Skibicka, K.P.2    Bence, K.K.3    Grill, H.J.4
  • 14
    • 47949104953 scopus 로고    scopus 로고
    • Caudal brainstem processing is sufficient for behavioral, sympathetic and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation
    • M.R. Hayes, K.P. Skibicka, and H.J. Grill Caudal brainstem processing is sufficient for behavioral, sympathetic and parasympathetic responses driven by peripheral and hindbrain glucagon-like-peptide-1 receptor stimulation Endocrinology 149 2008 4059 4068
    • (2008) Endocrinology , vol.149 , pp. 4059-4068
    • Hayes, M.R.1    Skibicka, K.P.2    Grill, H.J.3
  • 15
    • 66649088029 scopus 로고    scopus 로고
    • Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling
    • M.R. Hayes, L. Bradley, and H.J. Grill Endogenous hindbrain glucagon-like peptide-1 receptor activation contributes to the control of food intake by mediating gastric satiation signaling Endocrinology 150 2009 2654 2659
    • (2009) Endocrinology , vol.150 , pp. 2654-2659
    • Hayes, M.R.1    Bradley, L.2    Grill, H.J.3
  • 16
    • 66149185377 scopus 로고    scopus 로고
    • Dorsal hindbrain 5′-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance
    • M.R. Hayes, K.P. Skibicka, K.K. Bence, and H.J. Grill Dorsal hindbrain 5′-adenosine monophosphate-activated protein kinase as an intracellular mediator of energy balance Endocrinology 150 2009 2175 2182
    • (2009) Endocrinology , vol.150 , pp. 2175-2182
    • Hayes, M.R.1    Skibicka, K.P.2    Bence, K.K.3    Grill, H.J.4
  • 17
    • 77953724336 scopus 로고    scopus 로고
    • Role of the glucagon-like-peptide-1 receptor in the control of energy balance
    • M.R. Hayes, B.C. De Jonghe, and S.E. Kanoski Role of the glucagon-like-peptide-1 receptor in the control of energy balance Physiol. Behav. 100 2010 503 510
    • (2010) Physiol. Behav. , vol.100 , pp. 503-510
    • Hayes, M.R.1    De Jonghe, B.C.2    Kanoski, S.E.3
  • 18
    • 72649103549 scopus 로고    scopus 로고
    • Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation
    • M.R. Hayes, K.P. Skibicka, T.M. Leichner, D.J. Guarnieri, R.J. DiLeone, K.K. Bence, and H.J. Grill Endogenous leptin signaling in the caudal nucleus tractus solitarius and area postrema is required for energy balance regulation Cell Metab. 11 2010 77 83
    • (2010) Cell Metab. , vol.11 , pp. 77-83
    • Hayes, M.R.1    Skibicka, K.P.2    Leichner, T.M.3    Guarnieri, D.J.4    Dileone, R.J.5    Bence, K.K.6    Grill, H.J.7
  • 19
    • 35748957503 scopus 로고    scopus 로고
    • The physiology of glucagon-like peptide 1
    • DOI 10.1152/physrev.00034.2006
    • J.J. Holst The physiology of glucagon-like peptide 1 Physiol. Rev. 87 2007 1409 1439 (Pubitemid 350041474)
    • (2007) Physiological Reviews , vol.87 , Issue.4 , pp. 1409-1439
    • Holst, J.J.1
  • 20
    • 33644768285 scopus 로고    scopus 로고
    • Divergent regulation of proopiomelanocortin neurons by leptin in the nucleus of the solitary tract and in the arcuate hypothalamic nucleus
    • L. Huo, H.J. Grill, and C. Bjorbaek Divergent regulation of proopiomelanocortin neurons by leptin in the nucleus of the solitary tract and in the arcuate hypothalamic nucleus Diabetes 55 2006 567 573 (Pubitemid 43343211)
    • (2006) Diabetes , vol.55 , Issue.3 , pp. 567-573
    • Huo, L.1    Grill, H.J.2    Bjorbaek, C.3
  • 21
    • 33845972272 scopus 로고    scopus 로고
    • Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP
    • DOI 10.1074/jbc.M606676200
    • R.L. Hurley, L.K. Barre, S.D. Wood, K.A. Anderson, B.E. Kemp, A.R. Means, and L.A. Witters Regulation of AMP-activated protein kinase by multisite phosphorylation in response to agents that elevate cellular cAMP J. Biol. Chem. 281 2006 36662 36672 (Pubitemid 46042133)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.48 , pp. 36662-36672
    • Hurley, R.L.1    Barre, L.K.2    Wood, S.D.3    Anderson, K.A.4    Kemp, B.E.5    Means, A.R.6    Witters, L.A.7
  • 24
    • 23744515608 scopus 로고    scopus 로고
    • Role of hypothalamic 5′-AMP-activated protein kinase in the regulation of food intake and energy homeostasis
    • M.S. Kim, and K.U. Lee Role of hypothalamic 5′-AMP-activated protein kinase in the regulation of food intake and energy homeostasis J. Mol. Med. 83 2005 514 520
    • (2005) J. Mol. Med. , vol.83 , pp. 514-520
    • Kim, M.S.1    Lee, K.U.2
  • 27
    • 0036896243 scopus 로고    scopus 로고
    • The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness
    • K.P. Kinzig, D.A. D'Alessio, and R.J. Seeley The diverse roles of specific GLP-1 receptors in the control of food intake and the response to visceral illness J. Neurosci. 22 2002 10470 10476 (Pubitemid 35416883)
    • (2002) Journal of Neuroscience , vol.22 , Issue.23 , pp. 10470-10476
    • Kinzig, K.P.1    D'Alessio, D.A.2    Seeley, R.J.3
  • 28
    • 0024836493 scopus 로고
    • Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide
    • R. Komatsu, T. Matsuyama, M. Namba, N. Watanabe, H. Itoh, N. Kono, and S. Tarui Glucagonostatic and insulinotropic action of glucagonlike peptide I-(7-36)-amide Diabetes 38 1989 902 905 (Pubitemid 20022397)
    • (1989) Diabetes , vol.38 , Issue.7 , pp. 902-905
    • Komatsu, R.1    Matsuyama, T.2    Namba, M.3    Watanabe, N.4    Itoh, H.5    Kono, N.6    Tarui, S.7
  • 29
    • 0031029936 scopus 로고    scopus 로고
    • Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem
    • DOI 10.1016/S0306-4522(96)00434-4, PII S0306452296004344
    • P.J. Larsen, M. Tang-Christensen, J.J. Holst, and C. Orskov Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem Neuroscience 77 1997 257 270 (Pubitemid 27060323)
    • (1997) Neuroscience , vol.77 , Issue.1 , pp. 257-270
    • Larsen, P.J.1    Tang-Christensen, M.2    Holst, J.J.3    Orskov, C.4
  • 30
    • 0038804194 scopus 로고    scopus 로고
    • Central pre-proglucagon derived peptides: Oppurtunities for treatment of obesity
    • P.J. Larsen, N. Vrang, and M. Tang-Christensen Central pre-proglucagon derived peptides: opportunities for treatment of obesity Curr. Pharm. Des. 9 2003 1373 1382 (Pubitemid 36763979)
    • (2003) Current Pharmaceutical Design , vol.9 , Issue.17 , pp. 1373-1382
    • Larsen, P.J.1    Vrang, N.2    Tang-Christensen, M.3
  • 31
    • 67651173077 scopus 로고    scopus 로고
    • Incretin-based therapies for type 2 diabetes mellitus
    • J.A. Lovshin, and D.J. Drucker Incretin-based therapies for type 2 diabetes mellitus Nat. Rev. Endocrinol. 5 2009 262 269
    • (2009) Nat. Rev. Endocrinol. , vol.5 , pp. 262-269
    • Lovshin, J.A.1    Drucker, D.J.2
  • 32
    • 34447134870 scopus 로고    scopus 로고
    • Glucagon-like peptide 1 stimulates hypothalamic proopiomelanocortin neurons
    • DOI 10.1523/JNEUROSCI.1025-07.2007
    • X. Ma, J. Bruning, and F.M. Ashcroft Glucagon-like peptide 1 stimulates hypothalamic proopiomelanocortin neurons J. Neurosci. 27 2007 7125 7129 (Pubitemid 47037544)
    • (2007) Journal of Neuroscience , vol.27 , Issue.27 , pp. 7125-7129
    • Ma, X.1    Bruning, J.2    Ashcroft, F.M.3
  • 34
    • 0030819077 scopus 로고    scopus 로고
    • Decreased intake of a liquid diet in nonfood-deprived rats following intra-PVN injections of GLP-1 (7-36) amide
    • DOI 10.1016/S0091-3057(97)90017-4, PII S0091305797000178
    • L.R. McMahon, and P.J. Wellman Decreased intake of a liquid diet in nonfood-deprived rats following intra-PVN injections of GLP-1 (7-36) amide Pharmacol. Biochem. Behav. 58 1997 673 677 (Pubitemid 27438122)
    • (1997) Pharmacology Biochemistry and Behavior , vol.58 , Issue.3 , pp. 673-677
    • McMahon, L.R.1    Wellman, P.J.2
  • 35
    • 0031891391 scopus 로고    scopus 로고
    • PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats
    • L.R. McMahon, and P.J. Wellman PVN infusion of GLP-1-(7-36) amide suppresses feeding but does not induce aversion or alter locomotion in rats Am. J. Physiol. 274 1998 R23 R29
    • (1998) Am. J. Physiol. , vol.274
    • McMahon, L.R.1    Wellman, P.J.2
  • 36
    • 0033545166 scopus 로고    scopus 로고
    • Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system
    • DOI 10.1002/(SICI)1096-9861(19990111)403:2<261::AID-CNE8>3.0.CO;2-5
    • I. Merchenthaler, M. Lane, and P. Shughrue Distribution of pre-pro-glucagon and glucagon-like peptide-1 receptor messenger RNAs in the rat central nervous system J. Comp. Neurol. 403 1999 261 280 (Pubitemid 28566834)
    • (1999) Journal of Comparative Neurology , vol.403 , Issue.2 , pp. 261-280
    • Merchenthaler, I.1    Lane, M.2    Shughrue, P.3
  • 38
    • 1842523038 scopus 로고    scopus 로고
    • Infusion of the amylin antagonist AC 187 into the area postrema increases food intake in rats
    • DOI 10.1016/j.physbeh.2004.01.006, PII S0031938404000125
    • A. Mollet, S. Gilg, T. Riediger, and T.A. Lutz Infusion of the amylin antagonist AC 187 into the area postrema increases food intake in rats Physiol. Behav. 81 2004 149 155 (Pubitemid 38430051)
    • (2004) Physiology and Behavior , vol.81 , Issue.1 , pp. 149-155
    • Mollet, A.1    Gilg, S.2    Riediger, T.3    Lutz, T.A.4
  • 39
    • 0343363441 scopus 로고    scopus 로고
    • Fourth ventricular administration of glucagon-like peptide (7-36) amide (GLP-1) inhibits food intake in rats
    • T.H. Moran, A. Wohn, G.J. Schwartz, and E.E. Ladenheim Fourth ventricular administration of glucagon-like peptide (7-36) amide (GLP-1) inhibits food intake in rats Soc. Neurosci. 22 1996 15
    • (1996) Soc. Neurosci. , vol.22 , pp. 15
    • Moran, T.H.1    Wohn, A.2    Schwartz, G.J.3    Ladenheim, E.E.4
  • 40
    • 67650088267 scopus 로고    scopus 로고
    • The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling
    • G.J. Morton, J.E. Blevins, F. Kim, M. Matsen, and D.P. Figlewicz The action of leptin in the ventral tegmental area to decrease food intake is dependent on Jak-2 signaling Am. J. Physiol. Endocrinol. Metab. 297 2009 E202 E210
    • (2009) Am. J. Physiol. Endocrinol. Metab. , vol.297
    • Morton, G.J.1    Blevins, J.E.2    Kim, F.3    Matsen, M.4    Figlewicz, D.P.5
  • 43
    • 0034507515 scopus 로고    scopus 로고
    • Glucagon-like peptide-1: A major regulator of pancreatic β-cell function
    • R. Perfetti, and P. Merkel Glucagon-like peptide-1: a major regulator of pancreatic beta-cell function Eur. J. Endocrinol. 143 2000 717 725 (Pubitemid 32066697)
    • (2000) European Journal of Endocrinology , vol.143 , Issue.6 , pp. 717-725
    • Perfetti, R.1    Merkel, P.2
  • 44
    • 77953707385 scopus 로고    scopus 로고
    • Brainstem mechanisms of amylin-induced anorexia
    • C.S. Potes, and T.A. Lutz Brainstem mechanisms of amylin-induced anorexia Physiol. Behav. 100 2010 511 518
    • (2010) Physiol. Behav. , vol.100 , pp. 511-518
    • Potes, C.S.1    Lutz, T.A.2
  • 45
    • 67649636449 scopus 로고    scopus 로고
    • Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms
    • E.B. Ruttimann, M. Arnold, J.J. Hillebrand, N. Geary, and W. Langhans Intrameal hepatic portal and intraperitoneal infusions of glucagon-like peptide-1 reduce spontaneous meal size in the rat via different mechanisms Endocrinology 150 2009 1174 1181
    • (2009) Endocrinology , vol.150 , pp. 1174-1181
    • Ruttimann, E.B.1    Arnold, M.2    Hillebrand, J.J.3    Geary, N.4    Langhans, W.5
  • 46
    • 34548390977 scopus 로고    scopus 로고
    • The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size
    • K.A. Scott, and T.H. Moran The GLP-1 agonist exendin-4 reduces food intake in nonhuman primates through changes in meal size Am. J. Physiol. Regul. Integr. Comp. Physiol. 293 2007 R983 R987
    • (2007) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.293
    • Scott, K.A.1    Moran, T.H.2
  • 47
    • 55049140818 scopus 로고    scopus 로고
    • Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats
    • S. Seo, S. Ju, H. Chung, D. Lee, and S. Park Acute effects of glucagon-like peptide-1 on hypothalamic neuropeptide and AMP activated kinase expression in fasted rats Endocr. J. 55 2008 867 874
    • (2008) Endocr. J. , vol.55 , pp. 867-874
    • Seo, S.1    Ju, S.2    Chung, H.3    Lee, D.4    Park, S.5
  • 48
    • 0037302879 scopus 로고    scopus 로고
    • Hypothalamic administration of cAMP agonist/PKA activator inhibits both schedule feeding and NPY-induced feeding in rats
    • DOI 10.1016/S0196-9781(03)00037-8
    • S. Sheriff, W.T. Chance, S. Iqbal, T.A. Rizvi, C. Xiao, J.W. Kasckow, and A. Balasubramaniam Hypothalamic administration of cAMP agonist/PKA activator inhibits both schedule feeding and NPY-induced feeding in rats Peptides 24 2003 245 254 (Pubitemid 36369344)
    • (2003) Peptides , vol.24 , Issue.2 , pp. 245-254
    • Sheriff, S.1    Chance, W.T.2    Iqbal, S.3    Rizvi, T.A.4    Xiao, C.5    Kasckow, J.W.6    Balasubramaniam, A.7
  • 49
    • 8544257050 scopus 로고    scopus 로고
    • Extracellular signal-regulated kinase 1/2 signaling pathway in solitary nucleus mediates cholecystokinin-induced suppression of food intake in rats
    • DOI 10.1523/JNEUROSCI.2764-04.2004
    • G.M. Sutton, L.M. Patterson, and H.R. Berthoud Extracellular signal-regulated kinase 1/2 signaling pathway in solitary nucleus mediates cholecystokinin-induced suppression of food intake in rats J. Neurosci. 24 2004 10240 10247 (Pubitemid 39492051)
    • (2004) Journal of Neuroscience , vol.24 , Issue.45 , pp. 10240-10247
    • Sutton, G.M.1    Patterson, L.M.2    Berthoud, H.-R.3
  • 50
    • 23844542825 scopus 로고    scopus 로고
    • Melanocortinergic modulation of cholecystokinin-induced suppression of feeding through ERK signaling in rat solitary nucleus
    • DOI 10.1210/en.2005-0562
    • G.M. Sutton, B. Duos, L.M. Patterson, and H.R. Berthoud Melanocortinergic modulation of cholecystokinin-induced suppression of feeding through extracellular signal-regulated kinase signaling in rat solitary nucleus Endocrinology 146 2005 3739 3747 (Pubitemid 41175741)
    • (2005) Endocrinology , vol.146 , Issue.9 , pp. 3739-3747
    • Sutton, G.M.1    Duos, B.2    Patterson, L.M.3    Berthoud, H.-R.4
  • 52
    • 0030963439 scopus 로고    scopus 로고
    • cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway
    • M.R. Vossler, H. Yao, R.D. York, M.G. Pan, C.S. Rim, and P.J. Stork cAMP activates MAP kinase and Elk-1 through a B-Raf- and Rap1-dependent pathway Cell 89 1997 73 82 (Pubitemid 27180587)
    • (1997) Cell , vol.89 , Issue.1 , pp. 73-82
    • Vossler, M.R.1    Yao, H.2    York, R.D.3    Pan, M.-G.4    Rim, C.S.5    Stork, P.J.S.6
  • 55
    • 33745204479 scopus 로고    scopus 로고
    • AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues
    • DOI 10.1113/jphysiol.2006.113217
    • B. Xue, and B.B. Kahn AMPK integrates nutrient and hormonal signals to regulate food intake and energy balance through effects in the hypothalamus and peripheral tissues J. Physiol. 574 2006 73 83 (Pubitemid 43905798)
    • (2006) Journal of Physiology , vol.574 , Issue.1 , pp. 73-83
    • Xue, B.1    Kahn, B.B.2
  • 56
    • 23844525532 scopus 로고    scopus 로고
    • Expression of feeding-related peptide receptors mRNA in GT1-7 cell line and roles of leptin and orexins in control of GnRH secretion
    • DOI 10.1111/j.1745-7254.2005.00118.x
    • Y. Yang, L.B. Zhou, S.Q. Liu, J.F. Tang, F.Y. Li, R.Y. Li, H.D. Song, and M.D. Chen Expression of feeding-related peptide receptors mRNA in GT1-7 cell line and roles of leptin and orexins in control of GnRH secretion Acta Pharmacol. Sin. 26 2005 976 981 (Pubitemid 41153219)
    • (2005) Acta Pharmacologica Sinica , vol.26 , Issue.8 , pp. 976-981
    • Yang, Y.1    Zhou, L.-B.2    Liu, S.-Q.3    Tang, J.-F.4    Li, F.-Y.5    Li, R.-Y.6    Song, H.-D.7    Chen, M.-D.8


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