메뉴 건너뛰기




Volumn 187, Issue 8, 2011, Pages 4018-4030

Immunotherapy with costimulatory dendritic cells to control autoimmune inflammation

Author keywords

[No Author keywords available]

Indexed keywords

B7 ANTIGEN; CD28 ANTIGEN; CD3 ANTIGEN; CD86 ANTIGEN; DENDRITIC CELL VACCINE; GAMMA INTERFERON; INDOLEAMINE 2,3 DIOXYGENASE; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR RELB;

EID: 80054756076     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1101727     Document Type: Article
Times cited : (29)

References (86)
  • 1
    • 63449108301 scopus 로고    scopus 로고
    • Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
    • Ohnmacht, C., A. Pullner, S. B. King, I. Drexler, S. Meier, T. Brocker, and D. Voehringer. 2009. Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J. Exp. Med. 206: 549-559.
    • (2009) J. Exp. Med. , vol.206 , pp. 549-559
    • Ohnmacht, C.1    Pullner, A.2    King, S.B.3    Drexler, I.4    Meier, S.5    Brocker, T.6    Voehringer, D.7
  • 2
    • 77952520554 scopus 로고    scopus 로고
    • The balancing act of autoimmunity: Central and peripheral tolerance versus infection control
    • Thomas, R. 2010. The balancing act of autoimmunity: central and peripheral tolerance versus infection control. Int. Rev. Immunol. 29: 211-233.
    • (2010) Int. Rev. Immunol. , vol.29 , pp. 211-233
    • Thomas, R.1
  • 3
    • 0031871632 scopus 로고    scopus 로고
    • + T cells induced by cross- presentation of self-antigens involves signaling through CD95 (Fas, Apo-1)
    • DOI 10.1084/jem.188.2.415
    • Kurts, C., W. R. Heath, H. Kosaka, J. F. Miller, and F. R. Carbone. 1998. The peripheral deletion of autoreactive CD8+ T cells induced by cross-presentation of self-antigens involves signaling through CD95 (Fas, Apo-1). J. Exp. Med. 188: 415-420. (Pubitemid 28357771)
    • (1998) Journal of Experimental Medicine , vol.188 , Issue.2 , pp. 415-420
    • Kurts, C.1    Heath, W.R.2    Kosaka, H.3    Miller, J.F.A.P.4    Carbone, F.R.5
  • 5
    • 0037152162 scopus 로고    scopus 로고
    • Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
    • DOI 10.1084/jem.20020991
    • Scheinecker, C., R. McHugh, E. M. Shevach, and R. N. Germain. 2002. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 196: 1079-1090. (Pubitemid 35231766)
    • (2002) Journal of Experimental Medicine , vol.196 , Issue.8 , pp. 1079-1090
    • Scheinecker, C.1    McHugh, R.2    Shevach, E.M.3    Germain, R.N.4
  • 6
    • 0345448056 scopus 로고    scopus 로고
    • Physiological beta Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model
    • DOI 10.1084/jem.20030966
    • Turley, S., L. Poirot, M. Hattori, C. Benoist, and D. Mathis. 2003. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J. Exp. Med. 198: 1527-1537. (Pubitemid 37467167)
    • (2003) Journal of Experimental Medicine , vol.198 , Issue.10 , pp. 1527-1537
    • Turley, S.1    Poirot, L.2    Hattori, M.3    Benoist, C.4    Mathis, D.5
  • 7
    • 34249786244 scopus 로고    scopus 로고
    • + T cells
    • del Rio, M. L., J. I. Rodriguez-Barbosa, E. Kremmer, and R. Förster. 2007. CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. J. Immunol. 178: 6861-6866. (Pubitemid 46847411)
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 6861-6866
    • Del, R.M.-L.1    Rodriguez-Barbosa, J.-I.2    Kremmer, E.3    Forster, R.4
  • 8
    • 0038326717 scopus 로고    scopus 로고
    • Transfer of hematopoietic stem cells encoding autoantigen autoanfigen prevents autoimmune diabetes
    • DOI 10.1172/JCI200315995
    • Steptoe, R. J., J. M. Ritchie, and L. C. Harrison. 2003. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J. Clin. Invest. 111: 1357-1363. (Pubitemid 36554706)
    • (2003) Journal of Clinical Investigation , vol.111 , Issue.9 , pp. 1357-1363
    • Steptoe, R.J.1    Ritchie, J.M.2    Harrison, L.C.3
  • 9
    • 34547431144 scopus 로고    scopus 로고
    • Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-kappaB
    • DOI 10.1002/art.22655
    • Martin, E., C. Capini, E. Duggan, V. P. Lutzky, P. Stumbles, A. R. Pettit, B. O'Sullivan, and R. Thomas. 2007. Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-kappaB. Arthritis Rheum. 56: 2255-2266. (Pubitemid 47173574)
    • (2007) Arthritis and Rheumatism , vol.56 , Issue.7 , pp. 2255-2266
    • Martin, E.1    Capini, C.2    Duggan, E.3    Lutzky, V.P.4    Stumbles, P.5    Pettit, A.R.6    O'Sullivan, B.7    Thomas, R.8
  • 10
    • 0037240852 scopus 로고    scopus 로고
    • Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10
    • DOI 10.1016/S1074-7613(02)00503-4
    • Martin, E., B. O'Sullivan, P. Low, and R. Thomas. 2003. Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity 18: 155-167. (Pubitemid 36120696)
    • (2003) Immunity , vol.18 , Issue.1 , pp. 155-167
    • Martin, E.1    O'Sullivan, B.2    Low, P.3    Thomas, R.4
  • 11
    • 77953730386 scopus 로고    scopus 로고
    • Connecting the mechanisms of T-cell regulation: Dendritic cells as the missing link
    • Cobbold, S. P., E. Adams, K. F. Nolan, F. S. Regateiro, and H. Waldmann. 2010. Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link. Immunol. Rev. 236: 203-218.
    • (2010) Immunol. Rev. , vol.236 , pp. 203-218
    • Cobbold, S.P.1    Adams, E.2    Nolan, K.F.3    Regateiro, F.S.4    Waldmann, H.5
  • 12
    • 70449403221 scopus 로고    scopus 로고
    • B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function
    • Ruffner, M. A., S. H. Kim, N. R. Bianco, L. M. Francisco, A. H. Sharpe, and P. D. Robbins. 2009. B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function. Eur. J. Immunol. 39: 3084-3090.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 3084-3090
    • Ruffner, M.A.1    Kim, S.H.2    Bianco, N.R.3    Francisco, L.M.4    Sharpe, A.H.5    Robbins, P.D.6
  • 13
    • 12844274909 scopus 로고    scopus 로고
    • + Tr cells
    • DOI 10.1182/blood-2004-03-1211
    • Levings, M. K., S. Gregori, E. Tresoldi, S. Cazzaniga, C. Bonini, and M. G. Roncarolo. 2005. Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood 105: 1162-1169. (Pubitemid 40170889)
    • (2005) Blood , vol.105 , Issue.3 , pp. 1162-1169
    • Levings, M.K.1    Gregori, S.2    Tresoldi, E.3    Cazzaniga, S.4    Bonini, C.5    Roncarolo, M.G.6
  • 15
    • 70350433798 scopus 로고    scopus 로고
    • Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells
    • Jürgens, B., U. Hainz, D. Fuchs, T. Felzmann, and A. Heitger. 2009. Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells. Blood 114: 3235-3243.
    • (2009) Blood , vol.114 , pp. 3235-3243
    • Jürgens, B.1    Hainz, U.2    Fuchs, D.3    Felzmann, T.4    Heitger, A.5
  • 17
    • 78650666385 scopus 로고    scopus 로고
    • Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells
    • Mao, R., J. Zhang, D. Jiang, D. Cai, J. M. Levy, A. Cuconati, T. M. Block, J.-T. Guo, and H. Guo. 2011. Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells. J. Virol. 85: 1048-1057.
    • (2011) J. Virol. , vol.85 , pp. 1048-1057
    • Mao, R.1    Zhang, J.2    Jiang, D.3    Cai, D.4    Levy, J.M.5    Cuconati, A.6    Block, T.M.7    Guo, J.-T.8    Guo, H.9
  • 19
    • 0031279105 scopus 로고    scopus 로고
    • CD40 Ligand-CD40 Interactions Are Necessary for the Initiation of Insulitis and Diabetes in Nonobese Diabetic Mice
    • Balasa, B., T. Krahl, G. Patstone, J. Lee, R. Tisch, H. O. McDevitt, and N. Sarvetnick. 1997. CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice. J. Immunol. 159: 4620-4627. (Pubitemid 127470625)
    • (1997) Journal of Immunology , vol.159 , Issue.9 , pp. 4620-4627
    • Balasa, B.1    Krahl, T.2    Patstone, G.3    Lee, J.4    Tisch, R.5    McDevitt, H.O.6    Sarvetnick, N.7
  • 20
    • 0037248946 scopus 로고    scopus 로고
    • Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis
    • DOI 10.1089/10430340360464679
    • Feili-Hariri, M., D. H. Falkner, A. Gambotto, G. D. Papworth, S. C. Watkins, P. D. Robbins, and P. A. Morel. 2003. Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis. Hum. Gene Ther. 14: 13-23. (Pubitemid 36126684)
    • (2003) Human Gene Therapy , vol.14 , Issue.1 , pp. 13-23
    • Feili-Hariri, M.1    Falkner, D.H.2    Gambotto, A.3    Papworth, G.D.4    Watkins, S.C.5    Robbins, P.D.6    Morel, P.A.7
  • 21
    • 0042767606 scopus 로고    scopus 로고
    • Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity
    • DOI 10.2337/diabetes.52.8.1976
    • Ma, L., S. Qian, X. Liang, L. Wang, J. E. Woodward, N. Giannoukakis, P. D. Robbins, S. Bertera, M. Trucco, J. J. Fung, and L. Lu. 2003. Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity. Diabetes 52: 1976-1985. (Pubitemid 36919789)
    • (2003) Diabetes , vol.52 , Issue.8 , pp. 1976-1985
    • Ma, L.1    Qian, S.2    Liang, X.3    Wang, L.4    Woodward, J.E.5    Giannoukakis, N.6    Robbins, P.D.7    Bertera, S.8    Trucco, M.9    Fung, J.J.10    Lu, L.11
  • 22
    • 0032504602 scopus 로고    scopus 로고
    • Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice
    • Nitta, Y., F. Tashiro, M. Tokui, A. Shimada, I. Takei, K. Tabayashi, and J. Miyazaki. 1998. Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice. Hum. Gene Ther. 9: 1701-1707. (Pubitemid 28418740)
    • (1998) Human Gene Therapy , vol.9 , Issue.12 , pp. 1701-1707
    • Nitta, Y.1    Tashiro, F.2    Tokui, M.3    Shimada, A.4    Takei, I.5    Tabayashi, K.6    Miyazaki, J.-I.7
  • 23
    • 78751561859 scopus 로고    scopus 로고
    • Interleukin-1b produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy
    • Bertin-Maghit, S., D. Pang, B. O'Sullivan, S. Best, E. Duggan, S. Paul, H. Thomas, T. W. H. Kay, L. C. Harrison, R. Steptoe, and R. Thomas. 2011. Interleukin-1b produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy. Diabetes 60: 248-257.
    • (2011) Diabetes , vol.60 , pp. 248-257
    • Bertin-Maghit, S.1    Pang, D.2    O'Sullivan, B.3    Best, S.4    Duggan, E.5    Paul, S.6    Thomas, H.7    Kay, T.W.H.8    Harrison, L.C.9    Steptoe, R.10    Thomas, R.11
  • 26
    • 0036604277 scopus 로고    scopus 로고
    • CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB
    • O'Sullivan, B. J., and R. Thomas. 2002. CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB. J. Immunol. 168: 5491-5498. (Pubitemid 34556127)
    • (2002) Journal of Immunology , vol.168 , Issue.11 , pp. 5491-5498
    • O'Sullivan, B.J.1    Thomas, R.2
  • 28
    • 0031159205 scopus 로고    scopus 로고
    • Multifocal defects in immune responses in RelB-deficient mice
    • Weih, F., G. Warr, H. Yang, and R. Bravo. 1997. Multifocal defects in immune responses in RelB-deficient mice. J. Immunol. 158: 5211-5218. (Pubitemid 127681224)
    • (1997) Journal of Immunology , vol.158 , Issue.11 , pp. 5211-5218
    • Weih, F.1    Warr, G.2    Yang, H.3    Bravo, R.4
  • 30
    • 0028817585 scopus 로고
    • Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NFkappa B/Rel family
    • Weih, F., D. Carrasco, S. K. Durham, D. S. Barton, C. A. Rizzo, R. P. Ryseck, S. A. Lira, and R. Bravo. 1995. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NFkappa B/Rel family. Cell 80: 331-340.
    • (1995) Cell , vol.80 , pp. 331-340
    • Weih, F.1    Carrasco, D.2    Durham, S.K.3    Barton, D.S.4    Rizzo, C.A.5    Ryseck, R.P.6    Lira, S.A.7    Bravo, R.8
  • 31
    • 0029835390 scopus 로고    scopus 로고
    • Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
    • DOI 10.1038/383081a0
    • Laufer, T. M., J. DeKoning, J. S. Markowitz, D. Lo, and L. H. Glimcher. 1996. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 383: 81-85. (Pubitemid 26296465)
    • (1996) Nature , vol.383 , Issue.6595 , pp. 81-85
    • Laufer, T.M.1    DeKoning, J.2    Markowitz, J.S.3    Lo, D.4    Glimcher, L.H.5
  • 32
    • 0030292678 scopus 로고    scopus 로고
    • Both Multiorgan Inflammation and Myeloid Hyperplasia in RelB-Deficient Mice Are T Cell Dependent
    • Weih, F., S. K. Durham, D. S. Barton, W. C. Sha, D. Baltimore, and R. Bravo. 1996. Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent. J. Immunol. 157: 3974-3979. (Pubitemid 126449307)
    • (1996) Journal of Immunology , vol.157 , Issue.9 , pp. 3974-3979
    • Weih, F.1    Durham, S.K.2    Barton, D.S.3    Sha, W.C.4    Baltimore, D.5    Bravo, R.6
  • 34
    • 34249706306 scopus 로고    scopus 로고
    • Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD
    • DOI 10.1182/blood-2007-01-067249
    • MacDonald, K. P., R. D. Kuns, V. Rowe, E. S. Morris, T. Banovic, H. Bofinger, B. O'Sullivan, K. A. Markey, A. L. Don, R. Thomas, and G. R. Hill. 2007. Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD. Blood 109: 5049-5057. (Pubitemid 46827805)
    • (2007) Blood , vol.109 , Issue.11 , pp. 5049-5057
    • MacDonald, K.P.A.1    Kuns, R.D.2    Rowe, V.3    Morris, E.S.4    Banovic, T.5    Bofinger, H.6    O'Sullivan, B.7    Markey, K.A.8    Don, A.L.9    Thomas, R.10    Hill, G.R.11
  • 35
    • 0032530746 scopus 로고    scopus 로고
    • Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production
    • Schweitzer, A. N., and A. H. Sharpe. 1998. Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production. J. Immunol. 161: 2762-2771. (Pubitemid 28425695)
    • (1998) Journal of Immunology , vol.161 , Issue.6 , pp. 2762-2771
    • Schweitzer, A.N.1    Sharpe, A.H.2
  • 36
    • 0001722505 scopus 로고    scopus 로고
    • + dendritic cells
    • DOI 10.1016/S1074-7613(00)80649-4
    • Wu, L., A. D'Amico, K. D. Winkel, M. Suter, D. Lo, and K. Shortman. 1998. RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. Immunity 9: 839-847. (Pubitemid 29024463)
    • (1998) Immunity , vol.9 , Issue.6 , pp. 839-847
    • Wu, L.1    D'Amico, A.2    Winkel, K.D.3    Suter, M.4    Lo, D.5    Shortman, K.6
  • 38
    • 0037033427 scopus 로고    scopus 로고
    • Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
    • DOI 10.1084/jem.20011341
    • Menges, M., S. Rössner, C. Voigtländer, H. Schindler, N. A. Kukutsch, C. Bogdan, K. Erb, G. Schuler, and M. B. Lutz. 2002. Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J. Exp. Med. 195: 15-21. (Pubitemid 34074492)
    • (2002) Journal of Experimental Medicine , vol.195 , Issue.1 , pp. 15-21
    • Menges, M.1    Rossner, S.2    Voigtlander, C.3    Schindler, H.4    Kukutsch, N.A.5    Bogdan, C.6    Erb, K.7    Schuler, G.8    Lutz, M.B.9
  • 39
    • 38449092979 scopus 로고    scopus 로고
    • IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells
    • Geisel, J., F. Kahl, M. Müller, H. Wagner, C. J. Kirschning, I. B. Autenrieth, and J. S. Frick. 2007. IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells. J. Immunol. 179: 5811-5818.
    • (2007) J. Immunol. , vol.179 , pp. 5811-5818
    • Geisel, J.1    Kahl, F.2    Müller, M.3    Wagner, H.4    Kirschning, C.J.5    Autenrieth, I.B.6    Frick, J.S.7
  • 41
    • 0033847001 scopus 로고    scopus 로고
    • Mice lacking the transcription factor RelB develop T cell-dependent skin lesions similar to human atopic dermatitis
    • Barton, D., H. HogenEsch, and F. Weih. 2000. Mice lacking the transcription factor RelB develop T cell-dependent skin lesions similar to human atopic dermatitis. Eur. J. Immunol. 30: 2323-2332.
    • (2000) Eur. J. Immunol. , vol.30 , pp. 2323-2332
    • Barton, D.1    HogenEsch, H.2    Weih, F.3
  • 42
    • 33745224579 scopus 로고    scopus 로고
    • Regulation of naive T cell function by the NF-kappaB2 pathway
    • DOI 10.1038/ni1351, PII N1351
    • Ishimaru, N., H. Kishimoto, Y. Hayashi, and J. Sprent. 2006. Regulation of naive T cell function by the NF-kappaB2 pathway. Nat. Immunol. 7: 763-772. (Pubitemid 43905876)
    • (2006) Nature Immunology , vol.7 , Issue.7 , pp. 763-772
    • Ishimaru, N.1    Kishimoto, H.2    Hayashi, Y.3    Sprent, J.4
  • 43
    • 0037436119 scopus 로고    scopus 로고
    • + T cell-mediated suppression by dendritic cells
    • DOI 10.1126/science.1078231
    • Pasare, C., and R. Medzhitov. 2003. Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells. Science 299: 1033-1036. (Pubitemid 36222922)
    • (2003) Science , vol.299 , Issue.5609 , pp. 1033-1036
    • Pasare, C.1    Medzhitov, R.2
  • 45
    • 0033007321 scopus 로고    scopus 로고
    • Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
    • DOI 10.1146/annurev.immunol.17.1.221
    • Lenardo, M., K. M. Chan, F. Hornung, H. McFarland, R. Siegel, J. Wang, and L. Zheng. 1999. Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17: 221-253. (Pubitemid 29241124)
    • (1999) Annual Review of Immunology , vol.17 , pp. 221-253
    • Lenardo, M.1    Chan, F.K.-M.2    Hornung, F.3    McFarland, H.4    Siegel, R.5    Wang, J.6    Zheng, L.7
  • 46
    • 0030762656 scopus 로고    scopus 로고
    • RelB regulation of chemokine expression modulates local inflammation
    • Xia, Y., M. E. Pauza, L. Feng, and D. Lo. 1997. RelB regulation of chemokine expression modulates local inflammation. Am. J. Pathol. 151: 375-387. (Pubitemid 27330058)
    • (1997) American Journal of Pathology , vol.151 , Issue.2 , pp. 375-387
    • Xia, Y.1    Pauza, M.E.2    Feng, L.3    Lo, D.4
  • 48
    • 1642396607 scopus 로고    scopus 로고
    • + T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells
    • Munn, D. H., M. D. Sharma, and A. L. Mellor. 2004. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J. Immunol. 172: 4100-4110. (Pubitemid 38375222)
    • (2004) Journal of Immunology , vol.172 , Issue.7 , pp. 4100-4110
    • Munn, D.H.1    Sharma, M.D.2    Mellor, A.L.3
  • 49
    • 34548863106 scopus 로고    scopus 로고
    • Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation
    • DOI 10.1182/blood-2006-11-056010
    • Tas, S. W., M. J. Vervoordeldonk, N. Hajji, J. H. Schuitemaker, K. F. van der Sluijs, M. J. May, S. Ghosh, M. L. Kapsenberg, P. P. Tak, and E. C. de Jong. 2007. Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation. Blood 110: 1540-1549. (Pubitemid 47443970)
    • (2007) Blood , vol.110 , Issue.5 , pp. 1540-1549
    • Tas, S.W.1    Vervoordeldonk, M.J.2    Hajji, N.3    Schuitemaker, J.H.N.4    Van Der, S.K.F.5    May, M.J.6    Ghosh, S.7    Kapsenberg, M.L.8    Tak, P.P.9    De Jong, E.C.10
  • 51
    • 0028179230 scopus 로고
    • Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
    • Powrie, F., R. Correa-Oliveira, S. Mauze, and R. L. Coffman. 1994. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 179: 589-600.
    • (1994) J. Exp. Med. , vol.179 , pp. 589-600
    • Powrie, F.1    Correa-Oliveira, R.2    Mauze, S.3    Coffman, R.L.4
  • 52
    • 4043052238 scopus 로고    scopus 로고
    • Regulatory T cells and mechanisms of immune system control
    • DOI 10.1038/nm0804-801
    • O'Garra, A., and P. Vieira. 2004. Regulatory T cells and mechanisms of immune system control. Nat. Med. 10: 801-805. (Pubitemid 39070850)
    • (2004) Nature Medicine , vol.10 , Issue.8 , pp. 801-805
    • O'Garra, A.1    Vieira, P.2
  • 53
    • 0021271724 scopus 로고
    • Interleukin-2 reverses deficient cell-mediated immune responses in rheumatoid arthritis
    • Emery, P., G. S. Panayi, and A. M. Nouri. 1984. Interleukin-2 reverses deficient cell-mediated immune responses in rheumatoid arthritis. Clin. Exp. Immunol. 57: 123-129. (Pubitemid 14083836)
    • (1984) Clinical and Experimental Immunology , vol.57 , Issue.1 , pp. 123-129
    • Emery, P.1    Panayi, G.S.2    Nouri, A.M.E.3
  • 55
    • 0029003507 scopus 로고
    • Regulation of interleukin 2 gene expression by CD28 costimulation in mouse T-cell clones: Both nuclear and cytoplasmic RNAs are regulated with complex kinetics
    • Umlauf, S. W., B. Beverly, O. Lantz, and R. H. Schwartz. 1995. Regulation of interleukin 2 gene expression by CD28 costimulation in mouse T-cell clones: both nuclear and cytoplasmic RNAs are regulated with complex kinetics. Mol. Cell. Biol. 15: 3197-3205.
    • (1995) Mol. Cell. Biol. , vol.15 , pp. 3197-3205
    • Umlauf, S.W.1    Beverly, B.2    Lantz, O.3    Schwartz, R.H.4
  • 59
    • 34748835898 scopus 로고    scopus 로고
    • IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-kappaB activation
    • DOI 10.1038/nri2163, PII NRI2163
    • Puccetti, P., and U. Grohmann. 2007. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation. Nat. Rev. Immunol. 7: 817-823. (Pubitemid 47480306)
    • (2007) Nature Reviews Immunology , vol.7 , Issue.10 , pp. 817-823
    • Puccetti, P.1    Grohmann, U.2
  • 60
    • 18844457095 scopus 로고    scopus 로고
    • Mechanisms of type-I- and type-II-interferon-mediated signalling
    • DOI 10.1038/nri1604
    • Platanias, L. C. 2005. Mechanisms of type-I- and type-II-interferon- mediated signalling. Nat. Rev. Immunol. 5: 375-386. (Pubitemid 40685987)
    • (2005) Nature Reviews Immunology , vol.5 , Issue.5 , pp. 375-386
    • Platanias, L.C.1
  • 61
    • 63649161069 scopus 로고    scopus 로고
    • Curcumin suppresses the induction of indoleamine 2,3-dioxygenase by blocking the Janus-activated kinaseprotein kinase Cdelta-STAT1 signaling pathway in interferon-γ-stimulated murine dendritic cells
    • Jeong, Y.-I., S.W. Kim, I. D. Jung, J. S. Lee, J. H. Chang, C.-M. Lee, S. H. Chun, M.-S. Yoon, G. T. Kim, S. W. Ryu, et al. 2009. Curcumin suppresses the induction of indoleamine 2,3-dioxygenase by blocking the Janus-activated kinaseprotein kinase Cdelta-STAT1 signaling pathway in interferon-γ- stimulated murine dendritic cells. J. Biol. Chem. 284: 3700-3708.
    • (2009) J. Biol. Chem. , vol.284 , pp. 3700-3708
    • Jeong, Y.-I.1    Kim, S.W.2    Jung, I.D.3    Lee, J.S.4    Chang, J.H.5    Lee, C.-M.6    Chun, S.H.7    Yoon, M.-S.8    Kim, G.T.9    Ryu, S.W.10
  • 65
    • 33750614944 scopus 로고    scopus 로고
    • Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients
    • Banerjee, D. K., M. V. Dhodapkar, E. Matayeva, R. M. Steinman, and K. M. Dhodapkar. 2006. Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients. Blood 108: 2655-2661.
    • (2006) Blood , vol.108 , pp. 2655-2661
    • Banerjee, D.K.1    Dhodapkar, M.V.2    Matayeva, E.3    Steinman, R.M.4    Dhodapkar, K.M.5
  • 66
    • 1642454721 scopus 로고    scopus 로고
    • Regulation of Autoimmune Diabetes by Complete Freund's Adjuvant Is Mediated by NK Cells
    • Lee, I.-F., H. Qin, J. Trudeau, J. Dutz, and R. Tan. 2004. Regulation of autoimmune diabetes by complete Freund's adjuvant is mediated by NK cells. J. Immunol. 172: 937-942. (Pubitemid 38113752)
    • (2004) Journal of Immunology , vol.172 , Issue.2 , pp. 937-942
    • Lee, I.-F.1    Qin, H.2    Trudeau, J.3    Dutz, J.4    Tan, R.5
  • 67
    • 38349022508 scopus 로고    scopus 로고
    • Critical role for IFN-γ in natural killer cell-mediated protection from diabetes
    • Lee, I. F., H. Qin, J. J. Priatel, and R. Tan. 2008. Critical role for IFN-γ in natural killer cell-mediated protection from diabetes. Eur. J. Immunol. 38: 82-89.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 82-89
    • Lee, I.F.1    Qin, H.2    Priatel, J.J.3    Tan, R.4
  • 69
    • 0034680105 scopus 로고    scopus 로고
    • Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
    • Amrani, A., J. Verdaguer, P. Serra, S. Tafuro, R. Tan, and P. Santamaria. 2000. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature 406: 739-742.
    • (2000) Nature , vol.406 , pp. 739-742
    • Amrani, A.1    Verdaguer, J.2    Serra, P.3    Tafuro, S.4    Tan, R.5    Santamaria, P.6
  • 70
    • 0031569177 scopus 로고    scopus 로고
    • CD3 Antibody-Induced Dominant Self Tolerance in Overtly Diabetic NOD Mice
    • Chatenoud, L., J. Primo, and J. F. Bach. 1997. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J. Immunol. 158: 2947-2954. (Pubitemid 127470558)
    • (1997) Journal of Immunology , vol.158 , Issue.6 , pp. 2947-2954
    • Chatenoud, L.1    Primo, J.2    Bach, J.-F.3
  • 71
    • 77956254994 scopus 로고    scopus 로고
    • Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints
    • Nishio, J., M. Feuerer, J. Wong, D. Mathis, and C. Benoist. 2010. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J. Exp. Med. 207: 1879-1889.
    • (2010) J. Exp. Med. , vol.207 , pp. 1879-1889
    • Nishio, J.1    Feuerer, M.2    Wong, J.3    Mathis, D.4    Benoist, C.5
  • 72
    • 78751561859 scopus 로고    scopus 로고
    • Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy
    • Bertin-Maghit, S., D. Pang, B. O'Sullivan, S. Best, E. Duggan, S. Paul, H. Thomas, T. W. Kay, L. C. Harrison, R. Steptoe, and R. Thomas. 2011. Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy. Diabetes 60: 248-257.
    • (2011) Diabetes , vol.60 , pp. 248-257
    • Bertin-Maghit, S.1    Pang, D.2    O'Sullivan, B.3    Best, S.4    Duggan, E.5    Paul, S.6    Thomas, H.7    Kay, T.W.8    Harrison, L.C.9    Steptoe, R.10    Thomas, R.11
  • 76
    • 0028960483 scopus 로고
    • Defective maturation and function of antigen-presenting cells in type 1 diabetes
    • Jansen, A., M. van Hagen, and H. A. Drexhage. 1995. Defective maturation and function of antigen-presenting cells in type 1 diabetes. Lancet 345: 491-492.
    • (1995) Lancet , vol.345 , pp. 491-492
    • Jansen, A.1    Van Hagen, M.2    Drexhage, H.A.3
  • 77
    • 0036086041 scopus 로고    scopus 로고
    • Impaired primary immune response in type-1 diabetes: Results from a controlled vaccination study
    • DOI 10.1006/clim.2002.5220
    • Eibl, N., M. Spatz, G. F. Fischer, W. R. Mayr, A. Samstag, H. M. Wolf, G. Schernthaner, and M. M. Eibl. 2002. Impaired primary immune response in type-1 diabetes: results from a controlled vaccination study. Clin. Immunol. 103: 249-259. (Pubitemid 34666748)
    • (2002) Clinical Immunology , vol.103 , Issue.3 I , pp. 249-259
    • Eibl, N.1    Spatz, M.2    Fischer, G.F.3    Mayr, W.R.4    Samstag, A.5    Wolf, H.M.6    Schernthaner, G.7    Eibl, M.M.8
  • 78
    • 20044375937 scopus 로고    scopus 로고
    • A single course of anti-CD3 monoclonal antibody hOKT3gamma1(ala-ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
    • DOI 10.2337/diabetes.54.6.1763
    • Herold, K. C., S. E. Gitelman, U. Masharani, W. Hagopian, B. Bisikirska, D. Donaldson, K. Rother, B. Diamond, D. M. Harlan, and J. A. Bluestone. 2005. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54: 1763-1769. (Pubitemid 40770766)
    • (2005) Diabetes , vol.54 , Issue.6 , pp. 1763-1769
    • Herold, K.C.1    Gitelman, S.E.2    Masharani, U.3    Hagopian, W.4    Bisikirska, B.5    Donaldson, D.6    Rother, K.7    Diamond, B.8    Harlan, D.M.9    Bluestone, J.A.10
  • 82
    • 78649852489 scopus 로고    scopus 로고
    • Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses
    • Stoop, J. N., R. A. Harry, A. von Delwig, J. D. Isaacs, J. H. Robinson, and C. M. Hilkens. 2010. Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses. Arthritis Rheum. 62: 3656-3665.
    • (2010) Arthritis Rheum. , vol.62 , pp. 3656-3665
    • Stoop, J.N.1    Harry, R.A.2    Von Delwig, A.3    Isaacs, J.D.4    Robinson, J.H.5    Hilkens, C.M.6
  • 83
    • 59649083739 scopus 로고    scopus 로고
    • Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models
    • Bianco, N. R., S. H. Kim, M. A. Ruffner, and P. D. Robbins. 2009. Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models. Arthritis Rheum. 60: 380-389.
    • (2009) Arthritis Rheum. , vol.60 , pp. 380-389
    • Bianco, N.R.1    Kim, S.H.2    Ruffner, M.A.3    Robbins, P.D.4
  • 84
    • 49649098563 scopus 로고    scopus 로고
    • Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: Roles of IL-2 versus IL-15
    • Yang, C.-H., L. Tian, G.-S. Ling, N. J. Trendell-Smith, L. Ma, C.-K. Lo, D. I. Stott, F. Y. Liew, and F.-P. Huang. 2008. Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15. Eur. J. Immunol. 38: 1664-1676.
    • (2008) Eur. J. Immunol. , vol.38 , pp. 1664-1676
    • Yang, C.-H.1    Tian, L.2    Ling, G.-S.3    Trendell-Smith, N.J.4    Ma, L.5    Lo, C.-K.6    Stott, D.I.7    Liew, F.Y.8    Huang, F.-P.9
  • 85
    • 77952538760 scopus 로고    scopus 로고
    • Development of dendritic cell-based immunotherapy for autoimmunity
    • Hilkens, C. M., J. D. Isaacs, and A. W. Thomson. 2010. Development of dendritic cell-based immunotherapy for autoimmunity. Int. Rev. Immunol. 29: 156-183.
    • (2010) Int. Rev. Immunol. , vol.29 , pp. 156-183
    • Hilkens, C.M.1    Isaacs, J.D.2    Thomson, A.W.3
  • 86
    • 77649169766 scopus 로고    scopus 로고
    • Immune therapy for type 1 diabetes mellitus-what is unique about anti-CD3 antibodies?
    • Chatenoud, L. 2010. Immune therapy for type 1 diabetes mellitus-what is unique about anti-CD3 antibodies? Nat. Rev. Endocrinol. 6: 149-157.
    • (2010) Nat. Rev. Endocrinol. , vol.6 , pp. 149-157
    • Chatenoud, L.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.