-
1
-
-
63449108301
-
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
-
Ohnmacht, C., A. Pullner, S. B. King, I. Drexler, S. Meier, T. Brocker, and D. Voehringer. 2009. Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J. Exp. Med. 206: 549-559.
-
(2009)
J. Exp. Med.
, vol.206
, pp. 549-559
-
-
Ohnmacht, C.1
Pullner, A.2
King, S.B.3
Drexler, I.4
Meier, S.5
Brocker, T.6
Voehringer, D.7
-
2
-
-
77952520554
-
The balancing act of autoimmunity: Central and peripheral tolerance versus infection control
-
Thomas, R. 2010. The balancing act of autoimmunity: central and peripheral tolerance versus infection control. Int. Rev. Immunol. 29: 211-233.
-
(2010)
Int. Rev. Immunol.
, vol.29
, pp. 211-233
-
-
Thomas, R.1
-
3
-
-
0031871632
-
+ T cells induced by cross- presentation of self-antigens involves signaling through CD95 (Fas, Apo-1)
-
DOI 10.1084/jem.188.2.415
-
Kurts, C., W. R. Heath, H. Kosaka, J. F. Miller, and F. R. Carbone. 1998. The peripheral deletion of autoreactive CD8+ T cells induced by cross-presentation of self-antigens involves signaling through CD95 (Fas, Apo-1). J. Exp. Med. 188: 415-420. (Pubitemid 28357771)
-
(1998)
Journal of Experimental Medicine
, vol.188
, Issue.2
, pp. 415-420
-
-
Kurts, C.1
Heath, W.R.2
Kosaka, H.3
Miller, J.F.A.P.4
Carbone, F.R.5
-
4
-
-
0037152141
-
+ dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens
-
DOI 10.1084/jem.20020861
-
Belz, G. T., G. M. Behrens, C. M. Smith, J. F. Miller, C. Jones, K. Lejon, C. G. Fathman, S. N. Mueller, K. Shortman, F. R. Carbone, and W. R. Heath. 2002. The CD8alpha(+) dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens. J. Exp. Med. 196: 1099-1104. (Pubitemid 35231768)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.8
, pp. 1099-1104
-
-
Belz, G.T.1
Behrens, G.M.N.2
Smith, C.M.3
Miller, J.F.A.P.4
Jones, C.5
Lejon, K.6
Garrison, F.C.7
Mueller, S.N.8
Shortman, K.9
Carbone, F.R.10
Heath, W.R.11
-
5
-
-
0037152162
-
Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node
-
DOI 10.1084/jem.20020991
-
Scheinecker, C., R. McHugh, E. M. Shevach, and R. N. Germain. 2002. Constitutive presentation of a natural tissue autoantigen exclusively by dendritic cells in the draining lymph node. J. Exp. Med. 196: 1079-1090. (Pubitemid 35231766)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.8
, pp. 1079-1090
-
-
Scheinecker, C.1
McHugh, R.2
Shevach, E.M.3
Germain, R.N.4
-
6
-
-
0345448056
-
Physiological beta Cell Death Triggers Priming of Self-reactive T Cells by Dendritic Cells in a Type-1 Diabetes Model
-
DOI 10.1084/jem.20030966
-
Turley, S., L. Poirot, M. Hattori, C. Benoist, and D. Mathis. 2003. Physiological beta cell death triggers priming of self-reactive T cells by dendritic cells in a type-1 diabetes model. J. Exp. Med. 198: 1527-1537. (Pubitemid 37467167)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.10
, pp. 1527-1537
-
-
Turley, S.1
Poirot, L.2
Hattori, M.3
Benoist, C.4
Mathis, D.5
-
7
-
-
34249786244
-
+ T cells
-
del Rio, M. L., J. I. Rodriguez-Barbosa, E. Kremmer, and R. Förster. 2007. CD103- and CD103+ bronchial lymph node dendritic cells are specialized in presenting and cross-presenting innocuous antigen to CD4+ and CD8+ T cells. J. Immunol. 178: 6861-6866. (Pubitemid 46847411)
-
(2007)
Journal of Immunology
, vol.178
, Issue.11
, pp. 6861-6866
-
-
Del, R.M.-L.1
Rodriguez-Barbosa, J.-I.2
Kremmer, E.3
Forster, R.4
-
8
-
-
0038326717
-
Transfer of hematopoietic stem cells encoding autoantigen autoanfigen prevents autoimmune diabetes
-
DOI 10.1172/JCI200315995
-
Steptoe, R. J., J. M. Ritchie, and L. C. Harrison. 2003. Transfer of hematopoietic stem cells encoding autoantigen prevents autoimmune diabetes. J. Clin. Invest. 111: 1357-1363. (Pubitemid 36554706)
-
(2003)
Journal of Clinical Investigation
, vol.111
, Issue.9
, pp. 1357-1363
-
-
Steptoe, R.J.1
Ritchie, J.M.2
Harrison, L.C.3
-
9
-
-
34547431144
-
Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-kappaB
-
DOI 10.1002/art.22655
-
Martin, E., C. Capini, E. Duggan, V. P. Lutzky, P. Stumbles, A. R. Pettit, B. O'Sullivan, and R. Thomas. 2007. Antigen-specific suppression of established arthritis in mice by dendritic cells deficient in NF-kappaB. Arthritis Rheum. 56: 2255-2266. (Pubitemid 47173574)
-
(2007)
Arthritis and Rheumatism
, vol.56
, Issue.7
, pp. 2255-2266
-
-
Martin, E.1
Capini, C.2
Duggan, E.3
Lutzky, V.P.4
Stumbles, P.5
Pettit, A.R.6
O'Sullivan, B.7
Thomas, R.8
-
10
-
-
0037240852
-
Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10
-
DOI 10.1016/S1074-7613(02)00503-4
-
Martin, E., B. O'Sullivan, P. Low, and R. Thomas. 2003. Antigen-specific suppression of a primed immune response by dendritic cells mediated by regulatory T cells secreting interleukin-10. Immunity 18: 155-167. (Pubitemid 36120696)
-
(2003)
Immunity
, vol.18
, Issue.1
, pp. 155-167
-
-
Martin, E.1
O'Sullivan, B.2
Low, P.3
Thomas, R.4
-
11
-
-
77953730386
-
Connecting the mechanisms of T-cell regulation: Dendritic cells as the missing link
-
Cobbold, S. P., E. Adams, K. F. Nolan, F. S. Regateiro, and H. Waldmann. 2010. Connecting the mechanisms of T-cell regulation: dendritic cells as the missing link. Immunol. Rev. 236: 203-218.
-
(2010)
Immunol. Rev.
, vol.236
, pp. 203-218
-
-
Cobbold, S.P.1
Adams, E.2
Nolan, K.F.3
Regateiro, F.S.4
Waldmann, H.5
-
12
-
-
70449403221
-
B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function
-
Ruffner, M. A., S. H. Kim, N. R. Bianco, L. M. Francisco, A. H. Sharpe, and P. D. Robbins. 2009. B7-1/2, but not PD-L1/2 molecules, are required on IL-10-treated tolerogenic DC and DC-derived exosomes for in vivo function. Eur. J. Immunol. 39: 3084-3090.
-
(2009)
Eur. J. Immunol.
, vol.39
, pp. 3084-3090
-
-
Ruffner, M.A.1
Kim, S.H.2
Bianco, N.R.3
Francisco, L.M.4
Sharpe, A.H.5
Robbins, P.D.6
-
13
-
-
12844274909
-
+ Tr cells
-
DOI 10.1182/blood-2004-03-1211
-
Levings, M. K., S. Gregori, E. Tresoldi, S. Cazzaniga, C. Bonini, and M. G. Roncarolo. 2005. Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cells. Blood 105: 1162-1169. (Pubitemid 40170889)
-
(2005)
Blood
, vol.105
, Issue.3
, pp. 1162-1169
-
-
Levings, M.K.1
Gregori, S.2
Tresoldi, E.3
Cazzaniga, S.4
Bonini, C.5
Roncarolo, M.G.6
-
14
-
-
70149101645
-
IDO activates regulatory T cells and blocks their conversion into Th17-like T cells
-
Baban, B., P. R. Chandler, M. D. Sharma, J. Pihkala, P. A. Koni, D. H. Munn, and A. L. Mellor. 2009. IDO activates regulatory T cells and blocks their conversion into Th17-like T cells. J. Immunol. 183: 2475-2483.
-
(2009)
J. Immunol.
, vol.183
, pp. 2475-2483
-
-
Baban, B.1
Chandler, P.R.2
Sharma, M.D.3
Pihkala, J.4
Koni, P.A.5
Munn, D.H.6
Mellor, A.L.7
-
15
-
-
70350433798
-
Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells
-
Jürgens, B., U. Hainz, D. Fuchs, T. Felzmann, and A. Heitger. 2009. Interferon-gamma-triggered indoleamine 2,3-dioxygenase competence in human monocyte-derived dendritic cells induces regulatory activity in allogeneic T cells. Blood 114: 3235-3243.
-
(2009)
Blood
, vol.114
, pp. 3235-3243
-
-
Jürgens, B.1
Hainz, U.2
Fuchs, D.3
Felzmann, T.4
Heitger, A.5
-
16
-
-
77953729583
-
Blymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase
-
Johnson, B. A., III, D. J. Kahler, B. Baban, P. R. Chandler, B. Kang, M. Shimoda, P. A. Koni, J. Pihkala, B. Vilagos, M. Busslinger, et al. 2010. Blymphoid cells with attributes of dendritic cells regulate T cells via indoleamine 2,3-dioxygenase. Proc. Natl. Acad. Sci. USA 107: 10644-10648.
-
(2010)
Proc. Natl. Acad. Sci. USA
, vol.107
, pp. 10644-10648
-
-
Johnson III, B.A.1
Kahler, D.J.2
Baban, B.3
Chandler, P.R.4
Kang, B.5
Shimoda, M.6
Koni, P.A.7
Pihkala, J.8
Vilagos, B.9
Busslinger, M.10
-
17
-
-
78650666385
-
Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells
-
Mao, R., J. Zhang, D. Jiang, D. Cai, J. M. Levy, A. Cuconati, T. M. Block, J.-T. Guo, and H. Guo. 2011. Indoleamine 2,3-dioxygenase mediates the antiviral effect of gamma interferon against hepatitis B virus in human hepatocyte-derived cells. J. Virol. 85: 1048-1057.
-
(2011)
J. Virol.
, vol.85
, pp. 1048-1057
-
-
Mao, R.1
Zhang, J.2
Jiang, D.3
Cai, D.4
Levy, J.M.5
Cuconati, A.6
Block, T.M.7
Guo, J.-T.8
Guo, H.9
-
18
-
-
23844525846
-
A comprehensive review of interventions in the NOD mouse and implications for translation
-
DOI 10.1016/j.immuni.2005.08.002, PII S1074761305002402
-
Shoda, L. K., D. L. Young, S. Ramanujan, C. C. Whiting, M. A. Atkinson, J. A. Bluestone, G. S. Eisenbarth, D. Mathis, A. A. Rossini, S. E. Campbell, et al. 2005. A comprehensive review of interventions in the NOD mouse and implications for translation. Immunity 23: 115-126. (Pubitemid 41169282)
-
(2005)
Immunity
, vol.23
, Issue.2
, pp. 115-126
-
-
Shoda, L.K.M.1
Young, D.L.2
Ramanujan, S.3
Whiting, C.C.4
Atkinson, M.A.5
Bluestone, J.A.6
Eisenbarth, G.S.7
Mathis, D.8
Rossini, A.A.9
Campbell, S.E.10
Kahn, R.11
Kreuwel, H.T.C.12
-
19
-
-
0031279105
-
CD40 Ligand-CD40 Interactions Are Necessary for the Initiation of Insulitis and Diabetes in Nonobese Diabetic Mice
-
Balasa, B., T. Krahl, G. Patstone, J. Lee, R. Tisch, H. O. McDevitt, and N. Sarvetnick. 1997. CD40 ligand-CD40 interactions are necessary for the initiation of insulitis and diabetes in nonobese diabetic mice. J. Immunol. 159: 4620-4627. (Pubitemid 127470625)
-
(1997)
Journal of Immunology
, vol.159
, Issue.9
, pp. 4620-4627
-
-
Balasa, B.1
Krahl, T.2
Patstone, G.3
Lee, J.4
Tisch, R.5
McDevitt, H.O.6
Sarvetnick, N.7
-
20
-
-
0037248946
-
Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis
-
DOI 10.1089/10430340360464679
-
Feili-Hariri, M., D. H. Falkner, A. Gambotto, G. D. Papworth, S. C. Watkins, P. D. Robbins, and P. A. Morel. 2003. Dendritic cells transduced to express interleukin-4 prevent diabetes in nonobese diabetic mice with advanced insulitis. Hum. Gene Ther. 14: 13-23. (Pubitemid 36126684)
-
(2003)
Human Gene Therapy
, vol.14
, Issue.1
, pp. 13-23
-
-
Feili-Hariri, M.1
Falkner, D.H.2
Gambotto, A.3
Papworth, G.D.4
Watkins, S.C.5
Robbins, P.D.6
Morel, P.A.7
-
21
-
-
0042767606
-
Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity
-
DOI 10.2337/diabetes.52.8.1976
-
Ma, L., S. Qian, X. Liang, L. Wang, J. E. Woodward, N. Giannoukakis, P. D. Robbins, S. Bertera, M. Trucco, J. J. Fung, and L. Lu. 2003. Prevention of diabetes in NOD mice by administration of dendritic cells deficient in nuclear transcription factor-kappaB activity. Diabetes 52: 1976-1985. (Pubitemid 36919789)
-
(2003)
Diabetes
, vol.52
, Issue.8
, pp. 1976-1985
-
-
Ma, L.1
Qian, S.2
Liang, X.3
Wang, L.4
Woodward, J.E.5
Giannoukakis, N.6
Robbins, P.D.7
Bertera, S.8
Trucco, M.9
Fung, J.J.10
Lu, L.11
-
22
-
-
0032504602
-
Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice
-
Nitta, Y., F. Tashiro, M. Tokui, A. Shimada, I. Takei, K. Tabayashi, and J. Miyazaki. 1998. Systemic delivery of interleukin 10 by intramuscular injection of expression plasmid DNA prevents autoimmune diabetes in nonobese diabetic mice. Hum. Gene Ther. 9: 1701-1707. (Pubitemid 28418740)
-
(1998)
Human Gene Therapy
, vol.9
, Issue.12
, pp. 1701-1707
-
-
Nitta, Y.1
Tashiro, F.2
Tokui, M.3
Shimada, A.4
Takei, I.5
Tabayashi, K.6
Miyazaki, J.-I.7
-
23
-
-
78751561859
-
Interleukin-1b produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy
-
Bertin-Maghit, S., D. Pang, B. O'Sullivan, S. Best, E. Duggan, S. Paul, H. Thomas, T. W. H. Kay, L. C. Harrison, R. Steptoe, and R. Thomas. 2011. Interleukin-1b produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T-cells: Implications for the timing of tolerizing immunotherapy. Diabetes 60: 248-257.
-
(2011)
Diabetes
, vol.60
, pp. 248-257
-
-
Bertin-Maghit, S.1
Pang, D.2
O'Sullivan, B.3
Best, S.4
Duggan, E.5
Paul, S.6
Thomas, H.7
Kay, T.W.H.8
Harrison, L.C.9
Steptoe, R.10
Thomas, R.11
-
24
-
-
67651152594
-
Changes in autoreactive T cell avidity during type 1 diabetes development
-
Standifer, N. E., E. A. Burwell, V. H. Gersuk, C. J. Greenbaum, and G. T. Nepom. 2009. Changes in autoreactive T cell avidity during type 1 diabetes development. Clin. Immunol. 132: 312-320.
-
(2009)
Clin. Immunol.
, vol.132
, pp. 312-320
-
-
Standifer, N.E.1
Burwell, E.A.2
Gersuk, V.H.3
Greenbaum, C.J.4
Nepom, G.T.5
-
25
-
-
0031596028
-
A symptomatic synovitis precedes clinically manifest arthritis
-
DOI 10.1002/1529-0131(199808)41:8<1481::AID-ART19>3.0.CO;2-O
-
Kraan, M. C., H. Versendaal, M. Jonker, B. Bresnihan, W. J. Post, B. A. t Hart, F. C. Breedveld, and P. P. Tak. 1998. Asymptomatic synovitis precedes clinically manifest arthritis. Arthritis Rheum. 41: 1481-1488. (Pubitemid 28373129)
-
(1998)
Arthritis and Rheumatism
, vol.41
, Issue.8
, pp. 1481-1488
-
-
Kraan, M.C.1
Versendaal, H.2
Jonker, M.3
Bresnihan, B.4
Post, W.J.5
'T, H.B.A.6
Breedveld, F.C.7
Tak, P.P.8
-
26
-
-
0036604277
-
CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB
-
O'Sullivan, B. J., and R. Thomas. 2002. CD40 ligation conditions dendritic cell antigen-presenting function through sustained activation of NF-kappaB. J. Immunol. 168: 5491-5498. (Pubitemid 34556127)
-
(2002)
Journal of Immunology
, vol.168
, Issue.11
, pp. 5491-5498
-
-
O'Sullivan, B.J.1
Thomas, R.2
-
27
-
-
33846508178
-
An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha
-
Moore, F., S. Buonocore, E. Aksoy, N. Ouled-Haddou, S. Goriely, E. Lazarova, F. Paulart, C. Heirman, E. Vaeremans, K. Thielemans, et al. 2007. An alternative pathway of NF-kappaB activation results in maturation and T cell priming activity of dendritic cells overexpressing a mutated IkappaBalpha. J. Immunol. 178: 1301-1311. (Pubitemid 46154600)
-
(2007)
Journal of Immunology
, vol.178
, Issue.3
, pp. 1301-1311
-
-
Moore, F.1
Buonocore, S.2
Aksoy, E.3
Ouled-Haddou, N.4
Goriely, S.5
Lazarova, E.6
Paulart, F.7
Heirman, C.8
Vaeremans, E.9
Thielemans, K.10
Goldman, M.11
Flamand, V.12
-
28
-
-
0031159205
-
Multifocal defects in immune responses in RelB-deficient mice
-
Weih, F., G. Warr, H. Yang, and R. Bravo. 1997. Multifocal defects in immune responses in RelB-deficient mice. J. Immunol. 158: 5211-5218. (Pubitemid 127681224)
-
(1997)
Journal of Immunology
, vol.158
, Issue.11
, pp. 5211-5218
-
-
Weih, F.1
Warr, G.2
Yang, H.3
Bravo, R.4
-
29
-
-
0028952482
-
Expression of relB is required for the development of thymic medulla and dendritic cells
-
Burkly, L., C. Hession, L. Ogata, C. Reilly, L. A. Marconi, D. Olson, R. Tizard, R. Cate, and D. Lo. 1995. Expression of relB is required for the development of thymic medulla and dendritic cells. Nature 373: 531-536.
-
(1995)
Nature
, vol.373
, pp. 531-536
-
-
Burkly, L.1
Hession, C.2
Ogata, L.3
Reilly, C.4
Marconi, L.A.5
Olson, D.6
Tizard, R.7
Cate, R.8
Lo, D.9
-
30
-
-
0028817585
-
Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NFkappa B/Rel family
-
Weih, F., D. Carrasco, S. K. Durham, D. S. Barton, C. A. Rizzo, R. P. Ryseck, S. A. Lira, and R. Bravo. 1995. Multiorgan inflammation and hematopoietic abnormalities in mice with a targeted disruption of RelB, a member of the NFkappa B/Rel family. Cell 80: 331-340.
-
(1995)
Cell
, vol.80
, pp. 331-340
-
-
Weih, F.1
Carrasco, D.2
Durham, S.K.3
Barton, D.S.4
Rizzo, C.A.5
Ryseck, R.P.6
Lira, S.A.7
Bravo, R.8
-
31
-
-
0029835390
-
Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex
-
DOI 10.1038/383081a0
-
Laufer, T. M., J. DeKoning, J. S. Markowitz, D. Lo, and L. H. Glimcher. 1996. Unopposed positive selection and autoreactivity in mice expressing class II MHC only on thymic cortex. Nature 383: 81-85. (Pubitemid 26296465)
-
(1996)
Nature
, vol.383
, Issue.6595
, pp. 81-85
-
-
Laufer, T.M.1
DeKoning, J.2
Markowitz, J.S.3
Lo, D.4
Glimcher, L.H.5
-
32
-
-
0030292678
-
Both Multiorgan Inflammation and Myeloid Hyperplasia in RelB-Deficient Mice Are T Cell Dependent
-
Weih, F., S. K. Durham, D. S. Barton, W. C. Sha, D. Baltimore, and R. Bravo. 1996. Both multiorgan inflammation and myeloid hyperplasia in RelB-deficient mice are T cell dependent. J. Immunol. 157: 3974-3979. (Pubitemid 126449307)
-
(1996)
Journal of Immunology
, vol.157
, Issue.9
, pp. 3974-3979
-
-
Weih, F.1
Durham, S.K.2
Barton, D.S.3
Sha, W.C.4
Baltimore, D.5
Bravo, R.6
-
33
-
-
0037259791
-
CD4 T cell priming in dendritic cell-deficient mice
-
DOI 10.1093/intimm/dxg015
-
Castiglioni, P., C. Lu, D. Lo, M. Croft, P. Langlade-Demoyen, M. Zanetti, and M. Gerloni. 2003. CD4 T cell priming in dendritic cell-deficient mice. Int. Immunol. 15: 127-136. (Pubitemid 36163775)
-
(2003)
International Immunology
, vol.15
, Issue.1
, pp. 127-136
-
-
Catiglioni, P.1
Lu, C.2
Lo, D.3
Croft, M.4
Langlade-Demoyen, P.5
Zanetti, M.6
Gerloni, M.7
-
34
-
-
34249706306
-
Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD
-
DOI 10.1182/blood-2007-01-067249
-
MacDonald, K. P., R. D. Kuns, V. Rowe, E. S. Morris, T. Banovic, H. Bofinger, B. O'Sullivan, K. A. Markey, A. L. Don, R. Thomas, and G. R. Hill. 2007. Effector and regulatory T-cell function is differentially regulated by RelB within antigen-presenting cells during GVHD. Blood 109: 5049-5057. (Pubitemid 46827805)
-
(2007)
Blood
, vol.109
, Issue.11
, pp. 5049-5057
-
-
MacDonald, K.P.A.1
Kuns, R.D.2
Rowe, V.3
Morris, E.S.4
Banovic, T.5
Bofinger, H.6
O'Sullivan, B.7
Markey, K.A.8
Don, A.L.9
Thomas, R.10
Hill, G.R.11
-
35
-
-
0032530746
-
Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production
-
Schweitzer, A. N., and A. H. Sharpe. 1998. Studies using antigen-presenting cells lacking expression of both B7-1 (CD80) and B7-2 (CD86) show distinct requirements for B7 molecules during priming versus restimulation of Th2 but not Th1 cytokine production. J. Immunol. 161: 2762-2771. (Pubitemid 28425695)
-
(1998)
Journal of Immunology
, vol.161
, Issue.6
, pp. 2762-2771
-
-
Schweitzer, A.N.1
Sharpe, A.H.2
-
36
-
-
0001722505
-
+ dendritic cells
-
DOI 10.1016/S1074-7613(00)80649-4
-
Wu, L., A. D'Amico, K. D. Winkel, M. Suter, D. Lo, and K. Shortman. 1998. RelB is essential for the development of myeloid-related CD8alpha- dendritic cells but not of lymphoid-related CD8alpha+ dendritic cells. Immunity 9: 839-847. (Pubitemid 29024463)
-
(1998)
Immunity
, vol.9
, Issue.6
, pp. 839-847
-
-
Wu, L.1
D'Amico, A.2
Winkel, K.D.3
Suter, M.4
Lo, D.5
Shortman, K.6
-
37
-
-
0141678952
-
TRAF6 is a critical factor for dendritic cell maturation and development
-
DOI 10.1016/S1074-7613(03)00230-9
-
Kobayashi, T., P. T. Walsh, M. C. Walsh, K. M. Speirs, E. Chiffoleau, C. G. King, W. W. Hancock, J. H. Caamano, C. A. Hunter, P. Scott, et al. 2003. TRAF6 is a critical factor for dendritic cell maturation and development. Immunity 19: 353-363. (Pubitemid 37153412)
-
(2003)
Immunity
, vol.19
, Issue.3
, pp. 353-363
-
-
Kobayashi, T.1
Walsh, P.T.2
Walsh, M.C.3
Speirs, K.M.4
Chiffoleau, E.5
King, C.G.6
Hancock, W.W.7
Caamano, J.H.8
Hunter, C.A.9
Scott, P.10
Turka, L.A.11
Choi, Y.12
-
38
-
-
0037033427
-
Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity
-
DOI 10.1084/jem.20011341
-
Menges, M., S. Rössner, C. Voigtländer, H. Schindler, N. A. Kukutsch, C. Bogdan, K. Erb, G. Schuler, and M. B. Lutz. 2002. Repetitive injections of dendritic cells matured with tumor necrosis factor alpha induce antigen-specific protection of mice from autoimmunity. J. Exp. Med. 195: 15-21. (Pubitemid 34074492)
-
(2002)
Journal of Experimental Medicine
, vol.195
, Issue.1
, pp. 15-21
-
-
Menges, M.1
Rossner, S.2
Voigtlander, C.3
Schindler, H.4
Kukutsch, N.A.5
Bogdan, C.6
Erb, K.7
Schuler, G.8
Lutz, M.B.9
-
39
-
-
38449092979
-
IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells
-
Geisel, J., F. Kahl, M. Müller, H. Wagner, C. J. Kirschning, I. B. Autenrieth, and J. S. Frick. 2007. IL-6 and maturation govern TLR2 and TLR4 induced TLR agonist tolerance and cross-tolerance in dendritic cells. J. Immunol. 179: 5811-5818.
-
(2007)
J. Immunol.
, vol.179
, pp. 5811-5818
-
-
Geisel, J.1
Kahl, F.2
Müller, M.3
Wagner, H.4
Kirschning, C.J.5
Autenrieth, I.B.6
Frick, J.S.7
-
40
-
-
0345414139
-
Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice
-
DOI 10.1038/nature02119
-
Sakaguchi, N., T. Takahashi, H. Hata, T. Nomura, T. Tagami, S. Yamazaki, T. Sakihama, T. Matsutani, I. Negishi, S. Nakatsuru, and S. Sakaguchi. 2003. Altered thymic T-cell selection due to a mutation of the ZAP-70 gene causes autoimmune arthritis in mice. Nature 426: 454-460. (Pubitemid 37490133)
-
(2003)
Nature
, vol.426
, Issue.6965
, pp. 454-460
-
-
Sakaguchi, N.1
Takahashi, T.2
Hata, H.3
Nomura, T.4
Tagami, T.5
Yamazaki, S.6
Sakihama, T.7
Matsutani, T.8
Negishi, I.9
Nakatsuru, S.10
Sakaguchi, S.11
-
41
-
-
0033847001
-
Mice lacking the transcription factor RelB develop T cell-dependent skin lesions similar to human atopic dermatitis
-
Barton, D., H. HogenEsch, and F. Weih. 2000. Mice lacking the transcription factor RelB develop T cell-dependent skin lesions similar to human atopic dermatitis. Eur. J. Immunol. 30: 2323-2332.
-
(2000)
Eur. J. Immunol.
, vol.30
, pp. 2323-2332
-
-
Barton, D.1
HogenEsch, H.2
Weih, F.3
-
42
-
-
33745224579
-
Regulation of naive T cell function by the NF-kappaB2 pathway
-
DOI 10.1038/ni1351, PII N1351
-
Ishimaru, N., H. Kishimoto, Y. Hayashi, and J. Sprent. 2006. Regulation of naive T cell function by the NF-kappaB2 pathway. Nat. Immunol. 7: 763-772. (Pubitemid 43905876)
-
(2006)
Nature Immunology
, vol.7
, Issue.7
, pp. 763-772
-
-
Ishimaru, N.1
Kishimoto, H.2
Hayashi, Y.3
Sprent, J.4
-
43
-
-
0037436119
-
+ T cell-mediated suppression by dendritic cells
-
DOI 10.1126/science.1078231
-
Pasare, C., and R. Medzhitov. 2003. Toll pathway-dependent blockade of CD4+ CD25+ T cell-mediated suppression by dendritic cells. Science 299: 1033-1036. (Pubitemid 36222922)
-
(2003)
Science
, vol.299
, Issue.5609
, pp. 1033-1036
-
-
Pasare, C.1
Medzhitov, R.2
-
44
-
-
33744921639
-
+ effector T cells
-
O'Sullivan, B. J., H. E. Thomas, S. Pai, P. Santamaria, Y. Iwakura, R. J. Steptoe, T. W. Kay, and R. Thomas. 2006. IL-1 beta breaks tolerance through expansion of CD25+ effector T cells. J. Immunol. 176: 7278-7287. (Pubitemid 43849028)
-
(2006)
Journal of Immunology
, vol.176
, Issue.12
, pp. 7278-7287
-
-
O'Sullivan, B.J.1
Thomas, H.E.2
Pai, S.3
Santamaria, P.4
Iwakura, Y.5
Steptoe, R.J.6
Kay, T.W.H.7
Thomas, R.8
-
45
-
-
0033007321
-
Mature T lymphocyte apoptosis - Immune regulation in a dynamic and unpredictable antigenic environment
-
DOI 10.1146/annurev.immunol.17.1.221
-
Lenardo, M., K. M. Chan, F. Hornung, H. McFarland, R. Siegel, J. Wang, and L. Zheng. 1999. Mature T lymphocyte apoptosis - immune regulation in a dynamic and unpredictable antigenic environment. Annu. Rev. Immunol. 17: 221-253. (Pubitemid 29241124)
-
(1999)
Annual Review of Immunology
, vol.17
, pp. 221-253
-
-
Lenardo, M.1
Chan, F.K.-M.2
Hornung, F.3
McFarland, H.4
Siegel, R.5
Wang, J.6
Zheng, L.7
-
46
-
-
0030762656
-
RelB regulation of chemokine expression modulates local inflammation
-
Xia, Y., M. E. Pauza, L. Feng, and D. Lo. 1997. RelB regulation of chemokine expression modulates local inflammation. Am. J. Pathol. 151: 375-387. (Pubitemid 27330058)
-
(1997)
American Journal of Pathology
, vol.151
, Issue.2
, pp. 375-387
-
-
Xia, Y.1
Pauza, M.E.2
Feng, L.3
Lo, D.4
-
47
-
-
3442896883
-
Cytokine-regulated accumulation of eosinophils in inflammatory disease
-
DOI 10.1111/j.1398-9995.2004.00469.x
-
Lampinen, M., M. Carlson, L. D. Ha° kansson, and P. Venge. 2004. Cytokine-regulated accumulation of eosinophils in inflammatory disease. Allergy 59: 793-805. (Pubitemid 39005818)
-
(2004)
Allergy: European Journal of Allergy and Clinical Immunology
, vol.59
, Issue.8
, pp. 793-805
-
-
Lampinen, M.1
Carlson, M.2
Hakansson, L.D.3
Venge, P.4
-
48
-
-
1642396607
-
+ T Cells Triggers Indoleamine 2,3-Dioxygenase Activity in Dendritic Cells
-
Munn, D. H., M. D. Sharma, and A. L. Mellor. 2004. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J. Immunol. 172: 4100-4110. (Pubitemid 38375222)
-
(2004)
Journal of Immunology
, vol.172
, Issue.7
, pp. 4100-4110
-
-
Munn, D.H.1
Sharma, M.D.2
Mellor, A.L.3
-
49
-
-
34548863106
-
Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation
-
DOI 10.1182/blood-2006-11-056010
-
Tas, S. W., M. J. Vervoordeldonk, N. Hajji, J. H. Schuitemaker, K. F. van der Sluijs, M. J. May, S. Ghosh, M. L. Kapsenberg, P. P. Tak, and E. C. de Jong. 2007. Noncanonical NF-kappaB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation. Blood 110: 1540-1549. (Pubitemid 47443970)
-
(2007)
Blood
, vol.110
, Issue.5
, pp. 1540-1549
-
-
Tas, S.W.1
Vervoordeldonk, M.J.2
Hajji, N.3
Schuitemaker, J.H.N.4
Van Der, S.K.F.5
May, M.J.6
Ghosh, S.7
Kapsenberg, M.L.8
Tak, P.P.9
De Jong, E.C.10
-
50
-
-
34249725559
-
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
-
DOI 10.1038/nm1563, PII NM1563
-
Grohmann, U., C. Volpi, F. Fallarino, S. Bozza, R. Bianchi, C. Vacca, C. Orabona, M. L. Belladonna, E. Ayroldi, G. Nocentini, et al. 2007. Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy. Nat. Med. 13: 579-586. (Pubitemid 46828479)
-
(2007)
Nature Medicine
, vol.13
, Issue.5
, pp. 579-586
-
-
Grohmann, U.1
Volpi, C.2
Fallarino, F.3
Bozza, S.4
Bianchi, R.5
Vacca, C.6
Orabona, C.7
Belladonna, M.L.8
Ayroldi, E.9
Nocentini, G.10
Boon, L.11
Bistoni, F.12
Fioretti, M.C.13
Romani, L.14
Riccardi, C.15
Puccetti, P.16
-
51
-
-
0028179230
-
Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
-
Powrie, F., R. Correa-Oliveira, S. Mauze, and R. L. Coffman. 1994. Regulatory interactions between CD45RBhigh and CD45RBlow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity. J. Exp. Med. 179: 589-600.
-
(1994)
J. Exp. Med.
, vol.179
, pp. 589-600
-
-
Powrie, F.1
Correa-Oliveira, R.2
Mauze, S.3
Coffman, R.L.4
-
52
-
-
4043052238
-
Regulatory T cells and mechanisms of immune system control
-
DOI 10.1038/nm0804-801
-
O'Garra, A., and P. Vieira. 2004. Regulatory T cells and mechanisms of immune system control. Nat. Med. 10: 801-805. (Pubitemid 39070850)
-
(2004)
Nature Medicine
, vol.10
, Issue.8
, pp. 801-805
-
-
O'Garra, A.1
Vieira, P.2
-
53
-
-
0021271724
-
Interleukin-2 reverses deficient cell-mediated immune responses in rheumatoid arthritis
-
Emery, P., G. S. Panayi, and A. M. Nouri. 1984. Interleukin-2 reverses deficient cell-mediated immune responses in rheumatoid arthritis. Clin. Exp. Immunol. 57: 123-129. (Pubitemid 14083836)
-
(1984)
Clinical and Experimental Immunology
, vol.57
, Issue.1
, pp. 123-129
-
-
Emery, P.1
Panayi, G.S.2
Nouri, A.M.E.3
-
54
-
-
0034255127
-
T cell homeostasis in patients with rheumatoid arthritis
-
DOI 10.1073/pnas.97.16.9203
-
Koetz, K., E. Bryl, K. Spickschen, W. M. O'Fallon, J. J. Goronzy, and C. M. Weyand. 2000. T cell homeostasis in patients with rheumatoid arthritis. Proc. Natl. Acad. Sci. USA 97: 9203-9208. (Pubitemid 30626698)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.16
, pp. 9203-9208
-
-
Koetz, K.1
Bryl, E.2
Spickschen, K.3
O'Fallon, W.M.4
Goronzy, J.J.5
Weyand, C.M.6
-
55
-
-
0029003507
-
Regulation of interleukin 2 gene expression by CD28 costimulation in mouse T-cell clones: Both nuclear and cytoplasmic RNAs are regulated with complex kinetics
-
Umlauf, S. W., B. Beverly, O. Lantz, and R. H. Schwartz. 1995. Regulation of interleukin 2 gene expression by CD28 costimulation in mouse T-cell clones: both nuclear and cytoplasmic RNAs are regulated with complex kinetics. Mol. Cell. Biol. 15: 3197-3205.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 3197-3205
-
-
Umlauf, S.W.1
Beverly, B.2
Lantz, O.3
Schwartz, R.H.4
-
56
-
-
0036155562
-
+ dendritic cells
-
Fallarino, F., C. Vacca, C. Orabona, M. L. Belladonna, R. Bianchi, B. Marshall, D. B. Keskin, A. L. Mellor, M. C. Fioretti, U. Grohmann, and P. Puccetti. 2002. Functional expression of indoleamine 2,3-dioxygenase by murine CD8 alpha(+) dendritic cells. Int. Immunol. 14: 65-68. (Pubitemid 34083398)
-
(2002)
International Immunology
, vol.14
, Issue.1
, pp. 65-68
-
-
Fallarino, F.1
Vacca, C.2
Orabona, C.3
Belladonna, M.L.4
Bianchi, R.5
Marshall, B.6
Keskin, D.B.7
Mellor, A.L.8
Fioretti, M.C.9
Grohmann, U.10
Puccetti, P.11
-
57
-
-
0033519278
-
Inhibition of T cell proliferation by macrophage tryptophan catabolism
-
DOI 10.1084/jem.189.9.1363
-
Munn, D. H., E. Shafizadeh, J. T. Attwood, I. Bondarev, A. Pashine, and A. L. Mellor. 1999. Inhibition of T cell proliferation by macrophage tryptophan catabolism. J. Exp. Med. 189: 1363-1372. (Pubitemid 29227522)
-
(1999)
Journal of Experimental Medicine
, vol.189
, Issue.9
, pp. 1363-1372
-
-
Munn, D.H.1
Shafizadeh, E.2
Attwood, J.T.3
Bondarev, I.4
Pashine, A.5
Mellor, A.L.6
-
58
-
-
18544364477
-
Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase
-
DOI 10.1126/science.1073514
-
Munn, D. H., M. D. Sharma, J. R. Lee, K. G. Jhaver, T. S. Johnson, D. B. Keskin, B. Marshall, P. Chandler, S. J. Antonia, R. Burgess, et al. 2002. Potential regulatory function of human dendritic cells expressing indoleamine 2,3-dioxygenase. Science 297: 1867-1870. (Pubitemid 35024345)
-
(2002)
Science
, vol.297
, Issue.5588
, pp. 1867-1870
-
-
Munn, D.H.1
Sharma, M.D.2
Lee, J.R.3
Jhaver, K.G.4
Johnson, T.S.5
Keskin, D.B.6
Marshall, B.7
Chandler, P.8
Antonia, S.J.9
Burgess, R.10
Slingluff Jr., C.L.11
Mellor, A.L.12
-
59
-
-
34748835898
-
IDO and regulatory T cells: A role for reverse signalling and non-canonical NF-kappaB activation
-
DOI 10.1038/nri2163, PII NRI2163
-
Puccetti, P., and U. Grohmann. 2007. IDO and regulatory T cells: a role for reverse signalling and non-canonical NF-kappaB activation. Nat. Rev. Immunol. 7: 817-823. (Pubitemid 47480306)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.10
, pp. 817-823
-
-
Puccetti, P.1
Grohmann, U.2
-
60
-
-
18844457095
-
Mechanisms of type-I- and type-II-interferon-mediated signalling
-
DOI 10.1038/nri1604
-
Platanias, L. C. 2005. Mechanisms of type-I- and type-II-interferon- mediated signalling. Nat. Rev. Immunol. 5: 375-386. (Pubitemid 40685987)
-
(2005)
Nature Reviews Immunology
, vol.5
, Issue.5
, pp. 375-386
-
-
Platanias, L.C.1
-
61
-
-
63649161069
-
Curcumin suppresses the induction of indoleamine 2,3-dioxygenase by blocking the Janus-activated kinaseprotein kinase Cdelta-STAT1 signaling pathway in interferon-γ-stimulated murine dendritic cells
-
Jeong, Y.-I., S.W. Kim, I. D. Jung, J. S. Lee, J. H. Chang, C.-M. Lee, S. H. Chun, M.-S. Yoon, G. T. Kim, S. W. Ryu, et al. 2009. Curcumin suppresses the induction of indoleamine 2,3-dioxygenase by blocking the Janus-activated kinaseprotein kinase Cdelta-STAT1 signaling pathway in interferon-γ- stimulated murine dendritic cells. J. Biol. Chem. 284: 3700-3708.
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 3700-3708
-
-
Jeong, Y.-I.1
Kim, S.W.2
Jung, I.D.3
Lee, J.S.4
Chang, J.H.5
Lee, C.-M.6
Chun, S.H.7
Yoon, M.-S.8
Kim, G.T.9
Ryu, S.W.10
-
62
-
-
26444591571
-
Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders
-
DOI 10.1073/pnas.0504484102
-
Chorny, A., E. Gonzalez-Rey, A. Fernandez-Martin, D. Pozo, D. Ganea, and M. Delgado. 2005. Vasoactive intestinal peptide induces regulatory dendritic cells with therapeutic effects on autoimmune disorders. Proc. Natl. Acad. Sci. USA 102: 13562-13567. (Pubitemid 41420888)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.38
, pp. 13562-13567
-
-
Chorny, A.1
Gonzalez-Rey, E.2
Fernandez-Martin, A.3
Pozo, D.4
Ganea, D.5
Delgado, M.6
-
63
-
-
65449183747
-
Antigen-specific suppression of inflammatory arthritis using liposomes
-
Capini, C., M. Jaturanpinyo, H. I. Chang, S. Mutalik, A. McNally, S. Street, R. Steptoe, B. O'Sullivan, N. Davies, and R. Thomas. 2009. Antigen-specific suppression of inflammatory arthritis using liposomes. J. Immunol. 182: 3556-3565.
-
(2009)
J. Immunol.
, vol.182
, pp. 3556-3565
-
-
Capini, C.1
Jaturanpinyo, M.2
Chang, H.I.3
Mutalik, S.4
McNally, A.5
Street, S.6
Steptoe, R.7
O'Sullivan, B.8
Davies, N.9
Thomas, R.10
-
64
-
-
0042512461
-
+ regulatory T cells by antigen-processing dendritic cells
-
DOI 10.1084/jem.20030422
-
Yamazaki, S., T. Iyoda, K. Tarbell, K. Olson, K. Velinzon, K. Inaba, and R. M. Steinman. 2003. Direct expansion of functional CD25+ CD4+ regulatory T cells by antigen-processing dendritic cells. J. Exp. Med. 198: 235-247. (Pubitemid 37009740)
-
(2003)
Journal of Experimental Medicine
, vol.198
, Issue.2
, pp. 235-247
-
-
Yamazaki, S.1
Iyoda, T.2
Tarbell, K.3
Olson, K.4
Velinzon, K.5
Inaba, K.6
Steinman, R.M.7
-
65
-
-
33750614944
-
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients
-
Banerjee, D. K., M. V. Dhodapkar, E. Matayeva, R. M. Steinman, and K. M. Dhodapkar. 2006. Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients. Blood 108: 2655-2661.
-
(2006)
Blood
, vol.108
, pp. 2655-2661
-
-
Banerjee, D.K.1
Dhodapkar, M.V.2
Matayeva, E.3
Steinman, R.M.4
Dhodapkar, K.M.5
-
66
-
-
1642454721
-
Regulation of Autoimmune Diabetes by Complete Freund's Adjuvant Is Mediated by NK Cells
-
Lee, I.-F., H. Qin, J. Trudeau, J. Dutz, and R. Tan. 2004. Regulation of autoimmune diabetes by complete Freund's adjuvant is mediated by NK cells. J. Immunol. 172: 937-942. (Pubitemid 38113752)
-
(2004)
Journal of Immunology
, vol.172
, Issue.2
, pp. 937-942
-
-
Lee, I.-F.1
Qin, H.2
Trudeau, J.3
Dutz, J.4
Tan, R.5
-
67
-
-
38349022508
-
Critical role for IFN-γ in natural killer cell-mediated protection from diabetes
-
Lee, I. F., H. Qin, J. J. Priatel, and R. Tan. 2008. Critical role for IFN-γ in natural killer cell-mediated protection from diabetes. Eur. J. Immunol. 38: 82-89.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 82-89
-
-
Lee, I.F.1
Qin, H.2
Priatel, J.J.3
Tan, R.4
-
68
-
-
16044371193
-
CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes
-
DOI 10.1016/S1074-7613(00)80323-4
-
Lenschow, D. J., K. C. Herold, L. Rhee, B. Patel, A. Koons, H. Y. Qin, E. Fuchs, B. Singh, C. B. Thompson, and J. A. Bluestone. 1996. CD28/B7 regulation of Th1 and Th2 subsets in the development of autoimmune diabetes. Immunity 5: 285-293. (Pubitemid 26341371)
-
(1996)
Immunity
, vol.5
, Issue.3
, pp. 285-293
-
-
Lenschow, D.J.1
Herold, K.C.2
Rhee, L.3
Patel, B.4
Koons, A.5
Qin, H.-Y.6
Fuchs, E.7
Singh, B.8
Thompson, C.B.9
Bluestone, J.A.10
-
69
-
-
0034680105
-
Progression of autoimmune diabetes driven by avidity maturation of a T-cell population
-
Amrani, A., J. Verdaguer, P. Serra, S. Tafuro, R. Tan, and P. Santamaria. 2000. Progression of autoimmune diabetes driven by avidity maturation of a T-cell population. Nature 406: 739-742.
-
(2000)
Nature
, vol.406
, pp. 739-742
-
-
Amrani, A.1
Verdaguer, J.2
Serra, P.3
Tafuro, S.4
Tan, R.5
Santamaria, P.6
-
70
-
-
0031569177
-
CD3 Antibody-Induced Dominant Self Tolerance in Overtly Diabetic NOD Mice
-
Chatenoud, L., J. Primo, and J. F. Bach. 1997. CD3 antibody-induced dominant self tolerance in overtly diabetic NOD mice. J. Immunol. 158: 2947-2954. (Pubitemid 127470558)
-
(1997)
Journal of Immunology
, vol.158
, Issue.6
, pp. 2947-2954
-
-
Chatenoud, L.1
Primo, J.2
Bach, J.-F.3
-
71
-
-
77956254994
-
Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints
-
Nishio, J., M. Feuerer, J. Wong, D. Mathis, and C. Benoist. 2010. Anti-CD3 therapy permits regulatory T cells to surmount T cell receptor-specified peripheral niche constraints. J. Exp. Med. 207: 1879-1889.
-
(2010)
J. Exp. Med.
, vol.207
, pp. 1879-1889
-
-
Nishio, J.1
Feuerer, M.2
Wong, J.3
Mathis, D.4
Benoist, C.5
-
72
-
-
78751561859
-
Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy
-
Bertin-Maghit, S., D. Pang, B. O'Sullivan, S. Best, E. Duggan, S. Paul, H. Thomas, T. W. Kay, L. C. Harrison, R. Steptoe, and R. Thomas. 2011. Interleukin-1β produced in response to islet autoantigen presentation differentiates T-helper 17 cells at the expense of regulatory T cells: Implications for the timing of tolerizing immunotherapy. Diabetes 60: 248-257.
-
(2011)
Diabetes
, vol.60
, pp. 248-257
-
-
Bertin-Maghit, S.1
Pang, D.2
O'Sullivan, B.3
Best, S.4
Duggan, E.5
Paul, S.6
Thomas, H.7
Kay, T.W.8
Harrison, L.C.9
Steptoe, R.10
Thomas, R.11
-
73
-
-
77951882989
-
Reversal of autoimmunity by boosting memory-like autoregulatory T cells
-
Tsai, S., A. Shameli, J. Yamanouchi, X. Clemente-Casares, J. Wang, P. Serra, Y. Yang, Z. Medarova, A. Moore, and P. Santamaria. 2010. Reversal of autoimmunity by boosting memory-like autoregulatory T cells. Immunity 32: 568-580.
-
(2010)
Immunity
, vol.32
, pp. 568-580
-
-
Tsai, S.1
Shameli, A.2
Yamanouchi, J.3
Clemente-Casares, X.4
Wang, J.5
Serra, P.6
Yang, Y.7
Medarova, Z.8
Moore, A.9
Santamaria, P.10
-
74
-
-
49149097651
-
Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes
-
Mollah, Z. U., S. Pai, C. Moore, B. J. O'Sullivan, M. J. Harrison, J. Peng, K. Phillips, J. B. Prins, J. Cardinal, and R. Thomas. 2008. Abnormal NF-kappa B function characterizes human type 1 diabetes dendritic cells and monocytes. J. Immunol. 180: 3166-3175.
-
(2008)
J. Immunol.
, vol.180
, pp. 3166-3175
-
-
Mollah, Z.U.1
Pai, S.2
Moore, C.3
O'Sullivan, B.J.4
Harrison, M.J.5
Peng, J.6
Phillips, K.7
Prins, J.B.8
Cardinal, J.9
Thomas, R.10
-
75
-
-
28444469783
-
Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant
-
DOI 10.1038/ng1673, PII N1673
-
Vang, T., M. Congia, M. D. Macis, L. Musumeci, V. Orrú, P. Zavattari, K. Nika, L. Tautz, K. Taskén, F. Cucca, et al. 2005. Autoimmune-associated lymphoid tyrosine phosphatase is a gain-of-function variant. Nat. Genet. 37: 1317-1319. (Pubitemid 41722185)
-
(2005)
Nature Genetics
, vol.37
, Issue.12
, pp. 1317-1319
-
-
Vang, T.1
Congia, M.2
Macis, M.D.3
Musumeci, L.4
Orru, V.5
Zavattari, P.6
Nika, K.7
Tautz, L.8
Tasken, K.9
Cucca, F.10
Mustelin, T.11
Bottini, N.12
-
76
-
-
0028960483
-
Defective maturation and function of antigen-presenting cells in type 1 diabetes
-
Jansen, A., M. van Hagen, and H. A. Drexhage. 1995. Defective maturation and function of antigen-presenting cells in type 1 diabetes. Lancet 345: 491-492.
-
(1995)
Lancet
, vol.345
, pp. 491-492
-
-
Jansen, A.1
Van Hagen, M.2
Drexhage, H.A.3
-
77
-
-
0036086041
-
Impaired primary immune response in type-1 diabetes: Results from a controlled vaccination study
-
DOI 10.1006/clim.2002.5220
-
Eibl, N., M. Spatz, G. F. Fischer, W. R. Mayr, A. Samstag, H. M. Wolf, G. Schernthaner, and M. M. Eibl. 2002. Impaired primary immune response in type-1 diabetes: results from a controlled vaccination study. Clin. Immunol. 103: 249-259. (Pubitemid 34666748)
-
(2002)
Clinical Immunology
, vol.103
, Issue.3 I
, pp. 249-259
-
-
Eibl, N.1
Spatz, M.2
Fischer, G.F.3
Mayr, W.R.4
Samstag, A.5
Wolf, H.M.6
Schernthaner, G.7
Eibl, M.M.8
-
78
-
-
20044375937
-
A single course of anti-CD3 monoclonal antibody hOKT3gamma1(ala-ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes
-
DOI 10.2337/diabetes.54.6.1763
-
Herold, K. C., S. E. Gitelman, U. Masharani, W. Hagopian, B. Bisikirska, D. Donaldson, K. Rother, B. Diamond, D. M. Harlan, and J. A. Bluestone. 2005. A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes. Diabetes 54: 1763-1769. (Pubitemid 40770766)
-
(2005)
Diabetes
, vol.54
, Issue.6
, pp. 1763-1769
-
-
Herold, K.C.1
Gitelman, S.E.2
Masharani, U.3
Hagopian, W.4
Bisikirska, B.5
Donaldson, D.6
Rother, K.7
Diamond, B.8
Harlan, D.M.9
Bluestone, J.A.10
-
79
-
-
62749201002
-
Expansion of human regulatory T-cells from patients with type 1 diabetes
-
Putnam, A. L., T. M. Brusko, M. R. Lee, W. Liu, G. L. Szot, T. Ghosh, M. A. Atkinson, and J. A. Bluestone. 2009. Expansion of human regulatory T-cells from patients with type 1 diabetes. Diabetes 58: 652-662.
-
(2009)
Diabetes
, vol.58
, pp. 652-662
-
-
Putnam, A.L.1
Brusko, T.M.2
Lee, M.R.3
Liu, W.4
Szot, G.L.5
Ghosh, T.6
Atkinson, M.A.7
Bluestone, J.A.8
-
80
-
-
0035021177
-
Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis
-
Morita, Y., J. Yang, R. Gupta, K. Shimizu, E. A. Shelden, J. Endres, J. J. Mulé, K. T. McDonagh, and D. A. Fox. 2001. Dendritic cells genetically engineered to express IL-4 inhibit murine collagen-induced arthritis. J. Clin. Invest. 107: 1275-1284. (Pubitemid 32494544)
-
(2001)
Journal of Clinical Investigation
, vol.107
, Issue.10
, pp. 1275-1284
-
-
Morita, Y.1
Yang, J.2
Gupta, R.3
Shimizu, K.4
Shelden, E.A.5
Endres, J.6
Mule, J.J.7
McDonagh, K.T.8
Fox, D.A.9
-
81
-
-
5644291911
-
Antigen-specific immunomodulation of collagen-induced arthritis with tumor necrosis factor-stimulated dendritic cells
-
DOI 10.1002/art.20513
-
van Duivenvoorde, L. M., P. Louis-Plence, F. Apparailly, E. I. van der Voort, T. W. Huizinga, C. Jorgensen, and R. E. Toes. 2004. Antigen-specific immunomodulation of collagen-induced arthritis with tumor necrosis factor-stimulated dendritic cells. Arthritis Rheum. 50: 3354-3364. (Pubitemid 39372014)
-
(2004)
Arthritis and Rheumatism
, vol.50
, Issue.10
, pp. 3354-3364
-
-
Van Duivenvoorde, L.M.1
Louis-Plence, P.2
Apparailly, F.3
Van Der, V.E.I.H.4
Huizinga, T.W.J.5
Jorgensen, C.6
Toes, R.E.M.7
-
82
-
-
78649852489
-
Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses
-
Stoop, J. N., R. A. Harry, A. von Delwig, J. D. Isaacs, J. H. Robinson, and C. M. Hilkens. 2010. Therapeutic effect of tolerogenic dendritic cells in established collagen-induced arthritis is associated with a reduction in Th17 responses. Arthritis Rheum. 62: 3656-3665.
-
(2010)
Arthritis Rheum.
, vol.62
, pp. 3656-3665
-
-
Stoop, J.N.1
Harry, R.A.2
Von Delwig, A.3
Isaacs, J.D.4
Robinson, J.H.5
Hilkens, C.M.6
-
83
-
-
59649083739
-
Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models
-
Bianco, N. R., S. H. Kim, M. A. Ruffner, and P. D. Robbins. 2009. Therapeutic effect of exosomes from indoleamine 2,3-dioxygenase-positive dendritic cells in collagen-induced arthritis and delayed-type hypersensitivity disease models. Arthritis Rheum. 60: 380-389.
-
(2009)
Arthritis Rheum.
, vol.60
, pp. 380-389
-
-
Bianco, N.R.1
Kim, S.H.2
Ruffner, M.A.3
Robbins, P.D.4
-
84
-
-
49649098563
-
Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: Roles of IL-2 versus IL-15
-
Yang, C.-H., L. Tian, G.-S. Ling, N. J. Trendell-Smith, L. Ma, C.-K. Lo, D. I. Stott, F. Y. Liew, and F.-P. Huang. 2008. Immunological mechanisms and clinical implications of regulatory T cell deficiency in a systemic autoimmune disorder: roles of IL-2 versus IL-15. Eur. J. Immunol. 38: 1664-1676.
-
(2008)
Eur. J. Immunol.
, vol.38
, pp. 1664-1676
-
-
Yang, C.-H.1
Tian, L.2
Ling, G.-S.3
Trendell-Smith, N.J.4
Ma, L.5
Lo, C.-K.6
Stott, D.I.7
Liew, F.Y.8
Huang, F.-P.9
-
85
-
-
77952538760
-
Development of dendritic cell-based immunotherapy for autoimmunity
-
Hilkens, C. M., J. D. Isaacs, and A. W. Thomson. 2010. Development of dendritic cell-based immunotherapy for autoimmunity. Int. Rev. Immunol. 29: 156-183.
-
(2010)
Int. Rev. Immunol.
, vol.29
, pp. 156-183
-
-
Hilkens, C.M.1
Isaacs, J.D.2
Thomson, A.W.3
-
86
-
-
77649169766
-
Immune therapy for type 1 diabetes mellitus-what is unique about anti-CD3 antibodies?
-
Chatenoud, L. 2010. Immune therapy for type 1 diabetes mellitus-what is unique about anti-CD3 antibodies? Nat. Rev. Endocrinol. 6: 149-157.
-
(2010)
Nat. Rev. Endocrinol.
, vol.6
, pp. 149-157
-
-
Chatenoud, L.1
|