-
2
-
-
20844458756
-
Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis
-
Kim SH, Lechman ER, Bianco N, Menon R, Keravala A, Nash J, et al. Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis. J Immunol 2005;174:6440-8.
-
(2005)
J Immunol
, vol.174
, pp. 6440-6448
-
-
Kim, S.H.1
Lechman, E.R.2
Bianco, N.3
Menon, R.4
Keravala, A.5
Nash, J.6
-
3
-
-
30344460536
-
Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive
-
Kim SH, Bianco N, Menon R, Lechman ER, Shufesky WJ, Morelli AE, et al. Exosomes derived from genetically modified DC expressing FasL are anti-inflammatory and immunosuppressive. Mol Ther 2006;13:289-300.
-
(2006)
Mol Ther
, vol.13
, pp. 289-300
-
-
Kim, S.H.1
Bianco, N.2
Menon, R.3
Lechman, E.R.4
Shufesky, W.J.5
Morelli, A.E.6
-
4
-
-
34848915428
-
Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express IL-4
-
Kim SH, Bianco NR, Shufesky WJ, Morelli AE, Robbins PD. Effective treatment of inflammatory disease models with exosomes derived from dendritic cells genetically modified to express IL-4. J Immunol 2007;179:2242-9.
-
(2007)
J Immunol
, vol.179
, pp. 2242-2249
-
-
Kim, S.H.1
Bianco, N.R.2
Shufesky, W.J.3
Morelli, A.E.4
Robbins, P.D.5
-
5
-
-
4043092238
-
Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes
-
Munn DH, Sharma MD, Hou D, Baban B, Lee JR, Antonia SJ, et al. Expression of indoleamine 2,3-dioxygenase by plasmacytoid dendritic cells in tumor-draining lymph nodes. J Clin Invest 2004;114:280-90.
-
(2004)
J Clin Invest
, vol.114
, pp. 280-290
-
-
Munn, D.H.1
Sharma, M.D.2
Hou, D.3
Baban, B.4
Lee, J.R.5
Antonia, S.J.6
-
6
-
-
34249710405
-
Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19+ dendritic cells
-
Manlapat AK, Kahler DJ, Chandler PR, Munn DH, Mellor AL. Cell-autonomous control of interferon type I expression by indoleamine 2,3-dioxygenase in regulatory CD19+ dendritic cells. Eur J Immunol 2007;37:1064-71.
-
(2007)
Eur J Immunol
, vol.37
, pp. 1064-1071
-
-
Manlapat, A.K.1
Kahler, D.J.2
Chandler, P.R.3
Munn, D.H.4
Mellor, A.L.5
-
7
-
-
34748911754
-
Molecules in focus: Indoleamine 2,3-dioxygenase
-
King NJ, Thomas SR. Molecules in focus: indoleamine 2,3-dioxygenase. Int J Biochem Cell Biol 2007;39:2167-72.
-
(2007)
Int J Biochem Cell Biol
, vol.39
, pp. 2167-2172
-
-
King, N.J.1
Thomas, S.R.2
-
8
-
-
34548863106
-
Noncanonical NF-κB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation
-
Tas SW, Vervoordeldonk MJ, Hajji N, Schuitemaker JH, van der Sluijs KF, May MJ, et al. Noncanonical NF-κB signaling in dendritic cells is required for indoleamine 2,3-dioxygenase (IDO) induction and immune regulation. Blood 2007;110:1540-9.
-
(2007)
Blood
, vol.110
, pp. 1540-1549
-
-
Tas, S.W.1
Vervoordeldonk, M.J.2
Hajji, N.3
Schuitemaker, J.H.4
van der Sluijs, K.F.5
May, M.J.6
-
9
-
-
34249725559
-
Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy
-
Grohmann U, Volpi C, Fallarino F, Bozza S, Bianchi R, Vacca C, et al. Reverse signaling through GITR ligand enables dexamethasone to activate IDO in allergy. Nat Med 2007;13:579-86.
-
(2007)
Nat Med
, vol.13
, pp. 579-586
-
-
Grohmann, U.1
Volpi, C.2
Fallarino, F.3
Bozza, S.4
Bianchi, R.5
Vacca, C.6
-
10
-
-
5044220930
-
IDO expression by dendritic cells: Tolerance and tryptophan catabolism
-
Mellor AL, Munn DH. IDO expression by dendritic cells: tolerance and tryptophan catabolism. Nat Rev Immunol 2004;4:762-74.
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 762-774
-
-
Mellor, A.L.1
Munn, D.H.2
-
11
-
-
0032555614
-
Prevention of allogeneic fetal rejection by tryptophan catabolism
-
Munn DH, Zhou M, Attwood JT, Bondarev I, Conway SJ, Marshall B, et al. Prevention of allogeneic fetal rejection by tryptophan catabolism. Science 1998;281:1191-3.
-
(1998)
Science
, vol.281
, pp. 1191-1193
-
-
Munn, D.H.1
Zhou, M.2
Attwood, J.T.3
Bondarev, I.4
Conway, S.J.5
Marshall, B.6
-
12
-
-
0035221101
-
Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy
-
Mellor AL, Sivakumar J, Chandler P, Smith K, Molina H, Mao D, et al. Prevention of T cell-driven complement activation and inflammation by tryptophan catabolism during pregnancy. Nat Immunol 2001;2:64-8.
-
(2001)
Nat Immunol
, vol.2
, pp. 64-68
-
-
Mellor, A.L.1
Sivakumar, J.2
Chandler, P.3
Smith, K.4
Molina, H.5
Mao, D.6
-
13
-
-
34250349036
-
Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice
-
Szanto S, Koreny T, Mikecz K, Glant TT, Szekanecz Z, Varga J. Inhibition of indoleamine 2,3-dioxygenase-mediated tryptophan catabolism accelerates collagen-induced arthritis in mice. Arthritis Res Ther 2007;9:R50.
-
(2007)
Arthritis Res Ther
, vol.9
-
-
Szanto, S.1
Koreny, T.2
Mikecz, K.3
Glant, T.T.4
Szekanecz, Z.5
Varga, J.6
-
14
-
-
7044261952
-
4-1BB-mediated immunotherapy of rheumatoid arthritis
-
Seo SK, Choi JH, Kim YH, Kang WJ, Park HY, Suh JH, et al. 4-1BB-mediated immunotherapy of rheumatoid arthritis. Nat Med 2004;10:1088-94.
-
(2004)
Nat Med
, vol.10
, pp. 1088-1094
-
-
Seo, S.K.1
Choi, J.H.2
Kim, Y.H.3
Kang, W.J.4
Park, H.Y.5
Suh, J.H.6
-
15
-
-
34248173331
-
Indoleamine 2,3-dioxygenase and tumor-induced tolerance
-
Munn DH, Mellor AL. Indoleamine 2,3-dioxygenase and tumor-induced tolerance. J Clin Invest 2007;117:1147-54.
-
(2007)
J Clin Invest
, vol.117
, pp. 1147-1154
-
-
Munn, D.H.1
Mellor, A.L.2
-
16
-
-
0035995944
-
Indoleamine 2,3-dioxygenase expression in transplanted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes
-
Alexander AM, Crawford M, Bertera S, Rudert WA, Takikawa O, Robbins PD, et al. Indoleamine 2,3-dioxygenase expression in transplanted NOD islets prolongs graft survival after adoptive transfer of diabetogenic splenocytes. Diabetes 2002;51:356-65.
-
(2002)
Diabetes
, vol.51
, pp. 356-365
-
-
Alexander, A.M.1
Crawford, M.2
Bertera, S.3
Rudert, W.A.4
Takikawa, O.5
Robbins, P.D.6
-
17
-
-
1042291134
-
Tryptophan catabolism in nonobese diabetic mice
-
Grohmann U, Fallarino F, Bianchi R, Vacca C, Orabona C, Belladonna ML, et al. Tryptophan catabolism in nonobese diabetic mice. Adv Exp Med Biol 2003;527:47-54.
-
(2003)
Adv Exp Med Biol
, vol.527
, pp. 47-54
-
-
Grohmann, U.1
Fallarino, F.2
Bianchi, R.3
Vacca, C.4
Orabona, C.5
Belladonna, M.L.6
-
18
-
-
23444449846
-
Indolamine 2,3-dioxygenase is expressed in the CNS and downregulates autoimmune inflammation
-
Kwidzinski E, Bunse J, Aktas O, Richter F, Mutlu L, Zipp F, et al. Indolamine 2,3-dioxygenase is expressed in the CNS and downregulates autoimmune inflammation. FASEB J 2005;19:1347-9.
-
(2005)
FASEB J
, vol.19
, pp. 1347-1349
-
-
Kwidzinski, E.1
Bunse, J.2
Aktas, O.3
Richter, F.4
Mutlu, L.5
Zipp, F.6
-
19
-
-
27644587079
-
Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite
-
Platten M, Ho PP, Youssef S, Fontoura P, Garren H, Hur EM, et al. Treatment of autoimmune neuroinflammation with a synthetic tryptophan metabolite. Science 2005;310:850-5.
-
(2005)
Science
, vol.310
, pp. 850-855
-
-
Platten, M.1
Ho, P.P.2
Youssef, S.3
Fontoura, P.4
Garren, H.5
Hur, E.M.6
-
20
-
-
19344377474
-
GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase
-
Munn DH, Sharma MD, Baban B, Harding HP, Zhang Y, Ron D, et al. GCN2 kinase in T cells mediates proliferative arrest and anergy induction in response to indoleamine 2,3-dioxygenase. Immunity 2005;22:633-42.
-
(2005)
Immunity
, vol.22
, pp. 633-642
-
-
Munn, D.H.1
Sharma, M.D.2
Baban, B.3
Harding, H.P.4
Zhang, Y.5
Ron, D.6
-
21
-
-
33745304367
-
Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO
-
Belladonna ML, Grohmann U, Guidetti P, Volpi C, Bianchi R, Fioretti MC, et al. Kynurenine pathway enzymes in dendritic cells initiate tolerogenesis in the absence of functional IDO. J Immunol 2006;177:130-7.
-
(2006)
J Immunol
, vol.177
, pp. 130-137
-
-
Belladonna, M.L.1
Grohmann, U.2
Guidetti, P.3
Volpi, C.4
Bianchi, R.5
Fioretti, M.C.6
-
22
-
-
36248996016
-
Tryptophan catabolism generates autoimmune-preventive regulatory T cells
-
Fallarino F, Grohmann U, You S, McGrath BC, Cavener DR, Vacca C, et al. Tryptophan catabolism generates autoimmune-preventive regulatory T cells. Transpl Immunol 2006;17:58-60.
-
(2006)
Transpl Immunol
, vol.17
, pp. 58-60
-
-
Fallarino, F.1
Grohmann, U.2
You, S.3
McGrath, B.C.4
Cavener, D.R.5
Vacca, C.6
-
23
-
-
33646893538
-
The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells
-
Fallarino F, Grohmann U, You S, McGrath BC, Cavener DR, Vacca C, et al. The combined effects of tryptophan starvation and tryptophan catabolites down-regulate T cell receptor ζ-chain and induce a regulatory phenotype in naive T cells. J Immunol 2006;176:6752-61.
-
(2006)
J Immunol
, vol.176
, pp. 6752-6761
-
-
Fallarino, F.1
Grohmann, U.2
You, S.3
McGrath, B.C.4
Cavener, D.R.5
Vacca, C.6
-
24
-
-
39549096220
-
Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model
-
Park MJ, Min SY, Park KS, Cho YG, Cho ML, Jung YO, et al. Indoleamine 2,3-dioxygenase-expressing dendritic cells are involved in the generation of CD4+CD25+ regulatory T cells in Peyer's patches in an orally tolerized, collagen-induced arthritis mouse model. Arthritis Res Ther 2008;10:R11.
-
(2008)
Arthritis Res Ther
, vol.10
-
-
Park, M.J.1
Min, S.Y.2
Park, K.S.3
Cho, Y.G.4
Cho, M.L.5
Jung, Y.O.6
-
25
-
-
26444489716
-
A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation
-
Baban B, Hansen AM, Chandler PR, Manlapat A, Bingaman A, Kahler DJ, et al. A minor population of splenic dendritic cells expressing CD19 mediates IDO-dependent T cell suppression via type I IFN signaling following B7 ligation. Int Immunol 2005;17:909-19.
-
(2005)
Int Immunol
, vol.17
, pp. 909-919
-
-
Baban, B.1
Hansen, A.M.2
Chandler, P.R.3
Manlapat, A.4
Bingaman, A.5
Kahler, D.J.6
-
26
-
-
1642396607
-
Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells
-
Munn DH, Sharma MD, Mellor AL. Ligation of B7-1/B7-2 by human CD4+ T cells triggers indoleamine 2,3-dioxygenase activity in dendritic cells. J Immunol 2004;172:4100-10.
-
(2004)
J Immunol
, vol.172
, pp. 4100-4110
-
-
Munn, D.H.1
Sharma, M.D.2
Mellor, A.L.3
-
27
-
-
5044250291
-
Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase
-
Mellor AL, Chandler P, Baban B, Hansen AM, Marshall B, Pihkala J, et al. Specific subsets of murine dendritic cells acquire potent T cell regulatory functions following CTLA4-mediated induction of indoleamine 2,3 dioxygenase. Int Immunol 2004;16:1391-401.
-
(2004)
Int Immunol
, vol.16
, pp. 1391-1401
-
-
Mellor, A.L.1
Chandler, P.2
Baban, B.3
Hansen, A.M.4
Marshall, B.5
Pihkala, J.6
-
28
-
-
0036852170
-
CTLA-4-Ig regulates tryptophan catabolism in vivo
-
Grohmann U, Orabona C, Fallarino F, Vacca C, Calcinaro F, Falorni A, et al. CTLA-4-Ig regulates tryptophan catabolism in vivo. Nat Immunol 2002;3:1097-101.
-
(2002)
Nat Immunol
, vol.3
, pp. 1097-1101
-
-
Grohmann, U.1
Orabona, C.2
Fallarino, F.3
Vacca, C.4
Calcinaro, F.5
Falorni, A.6
-
29
-
-
0042193596
-
Increased degradation of tryptophan in blood of patients with rheumatoid arthritis
-
Schroecksnadel K, Kaser S, Ledochowski M, Neurauter G, Mur E, Herold M, et al. Increased degradation of tryptophan in blood of patients with rheumatoid arthritis. J Rheumatol 2003;30:1935-9.
-
(2003)
J Rheumatol
, vol.30
, pp. 1935-1939
-
-
Schroecksnadel, K.1
Kaser, S.2
Ledochowski, M.3
Neurauter, G.4
Mur, E.5
Herold, M.6
-
30
-
-
33751574468
-
Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition
-
Zhu L, Ji F, Wang Y, Zhang Y, Liu Q, Zhang JZ, et al. Synovial autoreactive T cells in rheumatoid arthritis resist IDO-mediated inhibition. J Immunol 2006;177:8226-33.
-
(2006)
J Immunol
, vol.177
, pp. 8226-8233
-
-
Zhu, L.1
Ji, F.2
Wang, Y.3
Zhang, Y.4
Liu, Q.5
Zhang, J.Z.6
-
31
-
-
0034469484
-
Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4
-
Kim SH, Evans CH, Kim S, Oligino T, Ghivizzani SC, Robbins PD. Gene therapy for established murine collagen-induced arthritis by local and systemic adenovirus-mediated delivery of interleukin-4. Arthritis Res 2000;2:293-302.
-
(2000)
Arthritis Res
, vol.2
, pp. 293-302
-
-
Kim, S.H.1
Evans, C.H.2
Kim, S.3
Oligino, T.4
Ghivizzani, S.C.5
Robbins, P.D.6
-
32
-
-
0036537831
-
A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells
-
Son YI, Egawa S, Tatsumi T, Redlinger RE Jr, Kalinski P, Kanto T. A novel bulk-culture method for generating mature dendritic cells from mouse bone marrow cells. J Immunol Methods 2002;262:145-57.
-
(2002)
J Immunol Methods
, vol.262
, pp. 145-157
-
-
Son, Y.I.1
Egawa, S.2
Tatsumi, T.3
Redlinger Jr, R.E.4
Kalinski, P.5
Kanto, T.6
-
33
-
-
0036851270
-
Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL
-
Kim SH, Kim S, Oligino TJ, Robbins PD. Effective treatment of established mouse collagen-induced arthritis by systemic administration of dendritic cells genetically modified to express FasL. Mol Ther 2002;6:584-90.
-
(2002)
Mol Ther
, vol.6
, pp. 584-590
-
-
Kim, S.H.1
Kim, S.2
Oligino, T.J.3
Robbins, P.D.4
-
34
-
-
2642530235
-
Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization
-
Laulagnier K, Motta C, Hamdi S, Roy S, Fauvelle F, Pageaux JF, et al. Mast cell- and dendritic cell-derived exosomes display a specific lipid composition and an unusual membrane organization. Biochem J 2004;380:161-71.
-
(2004)
Biochem J
, vol.380
, pp. 161-171
-
-
Laulagnier, K.1
Motta, C.2
Hamdi, S.3
Roy, S.4
Fauvelle, F.5
Pageaux, J.F.6
-
35
-
-
0345701525
-
Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59
-
Clayton A, Harris CL, Court J, Mason MD, Morgan BP. Antigen-presenting cell exosomes are protected from complement-mediated lysis by expression of CD55 and CD59. Eur J Immunol 2003;33:522-31.
-
(2003)
Eur J Immunol
, vol.33
, pp. 522-531
-
-
Clayton, A.1
Harris, C.L.2
Court, J.3
Mason, M.D.4
Morgan, B.P.5
-
36
-
-
38449100732
-
Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL
-
Luketic L, Delanghe J, Sobol PT, Yang P, Frotten E, Mossman KL, et al. Antigen presentation by exosomes released from peptide-pulsed dendritic cells is not suppressed by the presence of active CTL. J Immunol 2007;179:5024-32.
-
(2007)
J Immunol
, vol.179
, pp. 5024-5032
-
-
Luketic, L.1
Delanghe, J.2
Sobol, P.T.3
Yang, P.4
Frotten, E.5
Mossman, K.L.6
-
37
-
-
0037105629
-
Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-κ B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig
-
Bonham CA, Peng L, Liang X, Chen Z, Wang L, Ma L, et al. Marked prolongation of cardiac allograft survival by dendritic cells genetically engineered with NF-κ B oligodeoxyribonucleotide decoys and adenoviral vectors encoding CTLA4-Ig. J Immunol 2002;169:3382-91.
-
(2002)
J Immunol
, vol.169
, pp. 3382-3391
-
-
Bonham, C.A.1
Peng, L.2
Liang, X.3
Chen, Z.4
Wang, L.5
Ma, L.6
-
38
-
-
13544271675
-
Regulation of indoleamine 2,3-dioxygenase and tryptophanylt-RNA-synthetase by CTLA-4-Fc in human CD4+ T cells
-
Boasso A, Herbeuval JP, Hardy AW, Winkler C, Shearer GM. Regulation of indoleamine 2,3-dioxygenase and tryptophanylt-RNA-synthetase by CTLA-4-Fc in human CD4+ T cells. Blood 2005;105:1574-81.
-
(2005)
Blood
, vol.105
, pp. 1574-1581
-
-
Boasso, A.1
Herbeuval, J.P.2
Hardy, A.W.3
Winkler, C.4
Shearer, G.M.5
|