Flavonol kaempferol improves chronic hyperglycemia-impaired pancreatic beta-cell viability and insulin secretory function

European Journal of Pharmacology

Volumn 670, Issue 1, 2011, Pages 325-332

  Zhang, Yanling ^a,b   Liu, Dongmin ^b  

^a NORTHWESTERN POLYTECHNICAL UNIVERSITY   (China)

^b VIRGINIA POLYTECHNIC INSTITUTE AND STATE UNIVERSITY   (United States)

Author keywords

Beta cell viability; Hyperglycemia; Insulin secretion; Kaempferol

Indexed keywords

ADENOSINE TRIPHOSPHATE; CASPASE 3; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FLAVONOL; GLUCOSE; INSULIN; KAEMPFEROL; PROTEIN BCL 2; PROTEIN KINASE B;

APOPTOSIS; ARTICLE; CELL CLONE; CELL PROTECTION; CELL VIABILITY; CHRONIC DISEASE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFECT; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; HYPERGLYCEMIA; INSULIN RELEASE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

APOPTOSIS; CASPASE 3; CELL SURVIVAL; CHRONIC DISEASE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION; HUMANS; HYPERGLYCEMIA; INSULIN; INSULIN-SECRETING CELLS; INTRACELLULAR SPACE; KAEMPFEROLS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; SIGNAL TRANSDUCTION;

EID: 80054741464     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2011.08.011     Document Type: Article

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