The evolutionarily conserved longevity determinants HCF-1 and SIR-2.1/SIRT1 collaborate to regulate DAF-16/FOXO

PLoS Genetics

Volumn 7, Issue 9, 2011, Pages

  Rizki, Gizem ^a   Iwata, Terri Naoko ^a   Li, Ji ^a   Riedel, Christian G ^b   Picard, Colette Lafontaine ^a   Jan, Max ^c   Murphy, Coleen T ^c   Lee, Siu Sylvia ^a  

^a Department of Obstetrics Gynecology   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HOST CELL FACTOR C1; SIRTUIN 1; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR FOXO; CAENORHABDITIS ELEGANS PROTEIN; DAF 16 PROTEIN, C ELEGANS; DAF-16 PROTEIN, C ELEGANS; FORKHEAD TRANSCRIPTION FACTOR; FOXO3 PROTEIN, HUMAN; HCF 1 PROTEIN, C ELEGANS; HCF-1 PROTEIN, C ELEGANS; HCFC1 PROTEIN, HUMAN; SIR 2.1 PROTEIN, C ELEGANS; SIR-2.1 PROTEIN, C ELEGANS; SIRT1 PROTEIN, HUMAN; SIRTUIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR;

AGING; ARTICLE; CAENORHABDITIS ELEGANS; CONTROLLED STUDY; GENE EXPRESSION PROFILING; GENE MUTATION; GENE OVEREXPRESSION; GENE TARGETING; GENETIC CONSERVATION; HCF 1 GENE; HUMAN; HUMAN CELL; LIFESPAN; LONGEVITY; MAMMAL; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATOR GENE; SIR 2.1 GENE; TRANSCRIPTION REGULATION; WORM; ANIMAL; CELL STRAIN HEK293; GENETIC TRANSCRIPTION; GENETICS; METABOLISM; MOLECULAR EVOLUTION; PHYSIOLOGICAL STRESS; PHYSIOLOGY; SIGNAL TRANSDUCTION;

CAENORHABDITIS ELEGANS; MAMMALIA;

ANIMALS; CAENORHABDITIS ELEGANS; CAENORHABDITIS ELEGANS PROTEINS; EVOLUTION, MOLECULAR; FORKHEAD TRANSCRIPTION FACTORS; HEK293 CELLS; HOST CELL FACTOR C1; HUMANS; LONGEVITY; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; SIRTUIN 1; SIRTUINS; STRESS, PHYSIOLOGICAL; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC;

EID: 80053460544     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1002235     Document Type: Article

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