메뉴 건너뛰기




Volumn 2, Issue 11, 2006, Pages 1725-1739

p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans

Author keywords

[No Author keywords available]

Indexed keywords

LECTIN; MITOGEN ACTIVATED PROTEIN KINASE P38; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR DAF 16; TRANSCRIPTION FACTOR DAF 2; UNCLASSIFIED DRUG; BACTERIAL TOXIN; CAENORHABDITIS ELEGANS PROTEIN; DAF 16 PROTEIN, C ELEGANS; DAF 2 PROTEIN, C ELEGANS; DAF-16 PROTEIN, C ELEGANS; DAF-2 PROTEIN, C ELEGANS; INSULIN RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE; PMK 1 PROTEIN, C ELEGANS; PMK-1 PROTEIN, C ELEGANS;

EID: 33751382748     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.0020183     Document Type: Article
Times cited : (507)

References (58)
  • 1
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S, Uematsu S, Takeuchi O (2006) Pathogen recognition and innate immunity. Cell 124: 783-801.
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 2
    • 11844262607 scopus 로고    scopus 로고
    • Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans
    • Kim DH, Ausubel FM (2005) Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans. Curr Opin Immunol 17: 4-10.
    • (2005) Curr Opin Immunol , vol.17 , pp. 4-10
    • Kim, D.H.1    Ausubel, F.M.2
  • 4
    • 19644364800 scopus 로고    scopus 로고
    • Caenorhabditis elegans as a model for innate immunity to pathogens
    • Gravato-Nobre MJ, Hodgkin J (2005) Caenorhabditis elegans as a model for innate immunity to pathogens. Cell Microbiol 7: 741-751.
    • (2005) Cell Microbiol , vol.7 , pp. 741-751
    • Gravato-Nobre, M.J.1    Hodgkin, J.2
  • 5
    • 0037178731 scopus 로고    scopus 로고
    • A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity
    • Kim DH, Feinbaum R, Alloing G, Emerson FE, Garsin DA, et al. (2002) A conserved p38 MAP kinase pathway in Caenorhabditis elegans innate immunity. Science 297: 623-626.
    • (2002) Science , vol.297 , pp. 623-626
    • Kim, D.H.1    Feinbaum, R.2    Alloing, G.3    Emerson, F.E.4    Garsin, D.A.5
  • 6
    • 20644433073 scopus 로고    scopus 로고
    • ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity
    • Matsuzawa A, Saegusa K, Noguchi T, Sadamitsu C, Nishitoh H, et al. (2005) ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat Immunol 6: 587-592.
    • (2005) Nat Immunol , vol.6 , pp. 587-592
    • Matsuzawa, A.1    Saegusa, K.2    Noguchi, T.3    Sadamitsu, C.4    Nishitoh, H.5
  • 7
    • 13944269223 scopus 로고    scopus 로고
    • The plasticity of aging: Insights from long-lived mutants
    • Kenyon C (2005) The plasticity of aging: Insights from long-lived mutants. Cell 120: 449-460.
    • (2005) Cell , vol.120 , pp. 449-460
    • Kenyon, C.1
  • 8
    • 0027771804 scopus 로고
    • A C. elegans mutant that lives twice as long as wild type
    • Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R (1993) A C. elegans mutant that lives twice as long as wild type. Nature 366: 461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4    Tabtiang, R.5
  • 9
    • 0030813398 scopus 로고    scopus 로고
    • daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans
    • Kimura KD, Tissenbaum HA, Liu Y, Ruvkun G (1997) daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans. Science 277: 942-946.
    • (1997) Science , vol.277 , pp. 942-946
    • Kimura, K.D.1    Tissenbaum, H.A.2    Liu, Y.3    Ruvkun, G.4
  • 10
    • 0030657540 scopus 로고    scopus 로고
    • daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans
    • Lin K, Dorman JB, Rodan A, Kenyon C (1997) daf-16: An HNF-3/forkhead family member that can function to double the life-span of Caenorhabditis elegans. Science 278: 1319-1322.
    • (1997) Science , vol.278 , pp. 1319-1322
    • Lin, K.1    Dorman, J.B.2    Rodan, A.3    Kenyon, C.4
  • 11
    • 0030659557 scopus 로고    scopus 로고
    • The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
    • Ogg S, Paradis S, Gottlieb S, Patterson GI, Lee L, et al. (1997) The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans. Nature 389: 994-999.
    • (1997) Nature , vol.389 , pp. 994-999
    • Ogg, S.1    Paradis, S.2    Gottlieb, S.3    Patterson, G.I.4    Lee, L.5
  • 12
    • 0038047438 scopus 로고    scopus 로고
    • Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens
    • Garsin DA, Villanueva JM, Begun J, Kim DH, Sifri CD, et al. (2003) Long-lived C. elegans daf-2 mutants are resistant to bacterial pathogens. Science 300: 1921.
    • (2003) Science , vol.300 , pp. 1921
    • Garsin, D.A.1    Villanueva, J.M.2    Begun, J.3    Kim, D.H.4    Sifri, C.D.5
  • 13
    • 0042092531 scopus 로고    scopus 로고
    • Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
    • Murphy CT, McCarroll SA, Bargmann CI, Fraser A, Kamath RS, et al. (2003) Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans. Nature 424: 277-283.
    • (2003) Nature , vol.424 , pp. 277-283
    • Murphy, C.T.1    McCarroll, S.A.2    Bargmann, C.I.3    Fraser, A.4    Kamath, R.S.5
  • 14
    • 0042631524 scopus 로고    scopus 로고
    • Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16
    • McElwee J, Bubb K, Thomas JH (2003) Transcriptional outputs of the Caenorhabditis elegans forkhead protein DAF-16. Aging Cell 2: 111-121.
    • (2003) Aging Cell , vol.2 , pp. 111-121
    • McElwee, J.1    Bubb, K.2    Thomas, J.H.3
  • 16
    • 33748039462 scopus 로고    scopus 로고
    • Symbiotic bacteria direct expression of an intestinal bactericidal lectin
    • Cash HL, Whitham CV, Behrendt CL, Hooper LV (2006) Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science 313: 1126-1130.
    • (2006) Science , vol.313 , pp. 1126-1130
    • Cash, H.L.1    Whitham, C.V.2    Behrendt, C.L.3    Hooper, L.V.4
  • 17
    • 2442664007 scopus 로고    scopus 로고
    • TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM
    • Couillault C, Pujol N, Reboul J, Sabatier L, Guichou JF, et al. (2004) TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM. Nat Immunol 5: 488-494.
    • (2004) Nat Immunol , vol.5 , pp. 488-494
    • Couillault, C.1    Pujol, N.2    Reboul, J.3    Sabatier, L.4    Guichou, J.F.5
  • 18
    • 0037081820 scopus 로고    scopus 로고
    • abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans
    • Kato Y, Aizawa T, Hoshino H, Kawano K, Nitta K, et al. (2002) abf-1 and abf-2, ASABF-type antimicrobial peptide genes in Caenorhabditis elegans. Biochem J 361: 221-230.
    • (2002) Biochem J , vol.361 , pp. 221-230
    • Kato, Y.1    Aizawa, T.2    Hoshino, H.3    Kawano, K.4    Nitta, K.5
  • 19
    • 0345291179 scopus 로고    scopus 로고
    • Amoebapore homologs of Caenorhabditis elegans
    • Banyai L, Patthy L (1998) Amoebapore homologs of Caenorhabditis elegans. Biochim Biophys Acta 1429: 259-264.
    • (1998) Biochim Biophys Acta , vol.1429 , pp. 259-264
    • Banyai, L.1    Patthy, L.2
  • 20
    • 0035956931 scopus 로고    scopus 로고
    • Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing
    • Aballay A, Ausubel FM (2001) Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing. Proc Natl Acad Sci U S A 98: 2735-2739.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 2735-2739
    • Aballay, A.1    Ausubel, F.M.2
  • 21
    • 0037425599 scopus 로고    scopus 로고
    • Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway
    • Aballay A, Drenkard E, Hilbun LR, Ausubel FM (2003) Caenorhabditis elegans innate immune response triggered by Salmonella enterica requires intact LPS and is mediated by a MAPK signaling pathway. Curr Biol 13: 47-52.
    • (2003) Curr Biol , vol.13 , pp. 47-52
    • Aballay, A.1    Drenkard, E.2    Hilbun, L.R.3    Ausubel, F.M.4
  • 22
    • 33746727711 scopus 로고    scopus 로고
    • Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum
    • O'Rourke D, Baban D, Demidova M, Mott R, Hodgkin J (2006) Genomic clusters, putative pathogen recognition molecules, and antimicrobial genes are induced by infection of C. elegans with M. nematophilum. Genome Res. 16: 1005-1016.
    • (2006) Genome Res. , vol.16 , pp. 1005-1016
    • O'Rourke, D.1    Baban, D.2    Demidova, M.3    Mott, R.4    Hodgkin, J.5
  • 23
  • 24
    • 0036021375 scopus 로고    scopus 로고
    • Genetic analysis of tissue aging in Caenorhabditis elegans: A role for heat-shock factor and bacterial proliferation
    • Garigan D, Hsu AL, Fraser AG, Kamath RS, Ahringer J, et al. (2002) Genetic analysis of tissue aging in Caenorhabditis elegans: A role for heat-shock factor and bacterial proliferation. Genetics 161: 1101-1112.
    • (2002) Genetics , vol.161 , pp. 1101-1112
    • Garigan, D.1    Hsu, A.L.2    Fraser, A.G.3    Kamath, R.S.4    Ahringer, J.5
  • 25
    • 0034036321 scopus 로고    scopus 로고
    • Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans
    • Gems D, Riddle DL (2000) Genetic, behavioral and environmental determinants of male longevity in Caenorhabditis elegans. Genetics 154: 1597-1610.
    • (2000) Genetics , vol.154 , pp. 1597-1610
    • Gems, D.1    Riddle, D.L.2
  • 26
    • 0345447590 scopus 로고    scopus 로고
    • Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan
    • Libina N, Berman JR, Kenyon C (2003) Tissue-specific activities of C. elegans DAF-16 in the regulation of lifespan. Cell 115: 489-502.
    • (2003) Cell , vol.115 , pp. 489-502
    • Libina, N.1    Berman, J.R.2    Kenyon, C.3
  • 27
    • 26444442036 scopus 로고    scopus 로고
    • A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49
    • Van Gilst MR, Hadjivassiliou H, Yamamoto KR (2005) A Caenorhabditis elegans nutrient response system partially dependent on nuclear receptor NHR-49. Proc Natl Acad Sci U S A 102: 13496-13501.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 13496-13501
    • Van Gilst, M.R.1    Hadjivassiliou, H.2    Yamamoto, K.R.3
  • 28
    • 0033582314 scopus 로고    scopus 로고
    • Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis
    • Tan MW, Mahajan-Miklos S, Ausubel FM (1999) Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis. Proc Natl Acad Sci U S A 96: 715-720.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 715-720
    • Tan, M.W.1    Mahajan-Miklos, S.2    Ausubel, F.M.3
  • 29
    • 3342973834 scopus 로고    scopus 로고
    • The ERK MAP kinase cascade mediates tail swelling and a protective response to rectal infection in C. elegans
    • Nicholas HR, Hodgkin J (2004) The ERK MAP kinase cascade mediates tail swelling and a protective response to rectal infection in C. elegans. Curr Biol 14: 1256-1261.
    • (2004) Curr Biol , vol.14 , pp. 1256-1261
    • Nicholas, H.R.1    Hodgkin, J.2
  • 30
    • 7244238167 scopus 로고    scopus 로고
    • Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance
    • McElwee JJ, Schuster E, Blanc E, Thomas JH, Gems D (2004) Shared transcriptional signature in Caenorhabditis elegans Dauer larvae and long-lived daf-2 mutants implicates detoxification system in longevity assurance. J Biol Chem 279: 44533-44543.
    • (2004) J Biol Chem , vol.279 , pp. 44533-44543
    • McElwee, J.J.1    Schuster, E.2    Blanc, E.3    Thomas, J.H.4    Gems, D.5
  • 31
    • 0035846604 scopus 로고    scopus 로고
    • daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans
    • Henderson ST, Johnson TE (2001) daf-16 integrates developmental and environmental inputs to mediate aging in the nematode Caenorhabditis elegans. Curr Biol 11: 1975-1980.
    • (2001) Curr Biol , vol.11 , pp. 1975-1980
    • Henderson, S.T.1    Johnson, T.E.2
  • 32
    • 0035846601 scopus 로고    scopus 로고
    • Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway
    • Lee RY, Hench J, Ruvkun G (2001) Regulation of C. elegans DAF-16 and its human ortholog FKHRL1 by the daf-2 insulin-like signaling pathway. Curr Biol 11: 1950-1957.
    • (2001) Curr Biol , vol.11 , pp. 1950-1957
    • Lee, R.Y.1    Hench, J.2    Ruvkun, G.3
  • 34
    • 3042776968 scopus 로고    scopus 로고
    • Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry
    • Segerstrom SC, Miller GE (2004) Psychological stress and the human immune system: A meta-analytic study of 30 years of inquiry. Psychol Bull 130: 601-630.
    • (2004) Psychol Bull , vol.130 , pp. 601-630
    • Segerstrom, S.C.1    Miller, G.E.2
  • 35
    • 8544265317 scopus 로고    scopus 로고
    • Forkhead-box transcription factors and their role in the immune system
    • Coffer PJ, Burgering BM (2004) Forkhead-box transcription factors and their role in the immune system. Nat Rev Immunol 4: 889-899.
    • (2004) Nat Rev Immunol , vol.4 , pp. 889-899
    • Coffer, P.J.1    Burgering, B.M.2
  • 36
    • 12144290563 scopus 로고    scopus 로고
    • Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase
    • Brunet A, Sweeney LB, Sturgill JF, Chua KF, Greer PL, et al. (2004) Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase. Science 303: 2011-2015.
    • (2004) Science , vol.303 , pp. 2011-2015
    • Brunet, A.1    Sweeney, L.B.2    Sturgill, J.F.3    Chua, K.F.4    Greer, P.L.5
  • 37
    • 0037134040 scopus 로고    scopus 로고
    • DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein
    • Tran H, Brunet A, Grenier JM, Datta SR, Fornace AJ Jr., et al. (2002) DNA repair pathway stimulated by the forkhead transcription factor FOXO3a through the Gadd45 protein. Science 296: 530-534.
    • (2002) Science , vol.296 , pp. 530-534
    • Tran, H.1    Brunet, A.2    Grenier, J.M.3    Datta, S.R.4    Fornace Jr., A.J.5
  • 38
    • 0033965158 scopus 로고    scopus 로고
    • The p38 signal transduction pathway: Activation and function
    • Ono K, Han J (2000) The p38 signal transduction pathway: Activation and function. Cell Signal 12: 1-13.
    • (2000) Cell Signal , vol.12 , pp. 1-13
    • Ono, K.1    Han, J.2
  • 39
    • 33644753861 scopus 로고    scopus 로고
    • Analysis of homologous gene clusters in Caenorhabditis elegans reveals striking regional cluster domains
    • Thomas JH (2006) Analysis of homologous gene clusters in Caenorhabditis elegans reveals striking regional cluster domains. Genetics 172: 127-143.
    • (2006) Genetics , vol.172 , pp. 127-143
    • Thomas, J.H.1
  • 40
    • 0027190974 scopus 로고
    • The CUB domain. A widespread module in developmentally regulated proteins
    • Bork P, Beckmann G (1993) The CUB domain. A widespread module in developmentally regulated proteins. J Mol Biol 231: 539-545.
    • (1993) J Mol Biol , vol.231 , pp. 539-545
    • Bork, P.1    Beckmann, G.2
  • 41
    • 0242362732 scopus 로고    scopus 로고
    • JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila
    • Wang MC, Bohmann D, Jasper H (2003) JNK signaling confers tolerance to oxidative stress and extends lifespan in Drosophila. Dev Cell 5: 811-816.
    • (2003) Dev Cell , vol.5 , pp. 811-816
    • Wang, M.C.1    Bohmann, D.2    Jasper, H.3
  • 42
    • 15444371989 scopus 로고    scopus 로고
    • JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16
    • Oh SW, Mukhopadhyay A, Svrzikapa N, Jiang F, Davis RJ, et al. (2005) JNK regulates lifespan in Caenorhabditis elegans by modulating nuclear translocation of forkhead transcription factor/DAF-16. Proc Natl Acad Sci U S A 102: 4494-4499.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 4494-4499
    • Oh, S.W.1    Mukhopadhyay, A.2    Svrzikapa, N.3    Jiang, F.4    Davis, R.J.5
  • 43
    • 17044408768 scopus 로고    scopus 로고
    • JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling
    • Wang MC, Bohmann D, Jasper H (2005) JNK extends life span and limits growth by antagonizing cellular and organism-wide responses to insulin signaling. Cell 121: 115-125.
    • (2005) Cell , vol.121 , pp. 115-125
    • Wang, M.C.1    Bohmann, D.2    Jasper, H.3
  • 44
    • 21444454135 scopus 로고    scopus 로고
    • Intestinal microbiota
    • Lupp C, Finlay BB (2005) Intestinal microbiota. Curr Biol 15: R235-R236.
    • (2005) Curr Biol , vol.15
    • Lupp, C.1    Finlay, B.B.2
  • 48
    • 0016063911 scopus 로고
    • The genetics of Caenorhabditis elegans
    • Brenner S (1974) The genetics of Caenorhabditis elegans. Genetics 77: 71-94.
    • (1974) Genetics , vol.77 , pp. 71-94
    • Brenner, S.1
  • 49
    • 25844490465 scopus 로고    scopus 로고
    • The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response
    • Inoue H, Hisamoto N, An JH, Oliveira RP, Nishida E, et al. (2005) The C. elegans p38 MAPK pathway regulates nuclear localization of the transcription factor SKN-1 in oxidative stress response. Genes Dev 19: 2278-2283.
    • (2005) Genes Dev , vol.19 , pp. 2278-2283
    • Inoue, H.1    Hisamoto, N.2    An, J.H.3    Oliveira, R.P.4    Nishida, E.5
  • 52
    • 0030669030 scopus 로고    scopus 로고
    • Exploring the metabolic and genetic control of gene expression on a genomic scale
    • DeRisi JL, Iyer VR, Brown PO (1997) Exploring the metabolic and genetic control of gene expression on a genomic scale. Science 278: 680-686.
    • (1997) Science , vol.278 , pp. 680-686
    • DeRisi, J.L.1    Iyer, V.R.2    Brown, P.O.3
  • 53
    • 0035793050 scopus 로고    scopus 로고
    • Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans
    • Jiang M, Ryu J, Kiraly M, Duke K, Reinke V, et al. (2001) Genome-wide analysis of developmental and sex-regulated gene expression profiles in Caenorhabditis elegans. Proc Natl Acad Sci U S A 98: 218-223.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 218-223
    • Jiang, M.1    Ryu, J.2    Kiraly, M.3    Duke, K.4    Reinke, V.5
  • 54
    • 17344392308 scopus 로고    scopus 로고
    • A new mathematical model for relative quantification in real-time RT-PCR
    • Pfaffl MW (2001) A new mathematical model for relative quantification in real-time RT-PCR. Nucleic Acids Res 29: e45.
    • (2001) Nucleic Acids Res , vol.29
    • Pfaffl, M.W.1
  • 55
    • 0032578911 scopus 로고    scopus 로고
    • Specific interference by ingested dsRNA
    • Timmons L, Fire A (1998) Specific interference by ingested dsRNA. Nature 395: 854.
    • (1998) Nature , vol.395 , pp. 854
    • Timmons, L.1    Fire, A.2
  • 56
    • 0037448540 scopus 로고    scopus 로고
    • Systematic functional analysis of the Caenorhabditis elegans genome using RNAi
    • Kamath RS, Fraser AG, Dong Y, Poulin G, Durbin R, et al. (2003) Systematic functional analysis of the Caenorhabditis elegans genome using RNAi. Nature 421: 231-237.
    • (2003) Nature , vol.421 , pp. 231-237
    • Kamath, R.S.1    Fraser, A.G.2    Dong, Y.3    Poulin, G.4    Durbin, R.5
  • 57
    • 7444270371 scopus 로고    scopus 로고
    • Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library
    • Rual JF, Ceron J, Koreth J, Hao T, Nicot AS, et al. (2004) Toward improving Caenorhabditis elegans phenome mapping with an ORFeome-based RNAi library. Genome Res 14: 2162-2168.
    • (2004) Genome Res , vol.14 , pp. 2162-2168
    • Rual, J.F.1    Ceron, J.2    Koreth, J.3    Hao, T.4    Nicot, A.S.5
  • 58
    • 33749014641 scopus 로고    scopus 로고
    • A conserved role for a GATA transcription factor in regulating epithelial innate immune responses
    • Shapira M, Hamlin BJ, Rong J, Chen K, Ronen M, et al. (2006) A conserved role for a GATA transcription factor in regulating epithelial innate immune responses. Proc Natl Acad Sci USA 103: 14086-14091.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 14086-14091
    • Shapira, M.1    Hamlin, B.J.2    Rong, J.3    Chen, K.4    Ronen, M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.