메뉴 건너뛰기




Volumn 11, Issue 10, 2011, Pages 1399-1406

Toll like receptors in diseases of the lung

Author keywords

DAMPs; Immunity; Lung; PAMPs; Pathogen recognition receptors

Indexed keywords

CPG OLIGODEOXYNUCLEOTIDE; PATHOGEN ASSOCIATED MOLECULAR PATTERN RECEPTOR; PATTERN RECOGNITION RECEPTOR; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TOLL LIKE RECEPTOR 9; UNCLASSIFIED DRUG;

EID: 80053289161     PISSN: 15675769     EISSN: 18781705     Source Type: Journal    
DOI: 10.1016/j.intimp.2011.05.013     Document Type: Review
Times cited : (81)

References (118)
  • 1
    • 33747483267 scopus 로고    scopus 로고
    • The role of Toll-like receptors in non-infectious lung injury
    • DOI 10.1038/sj.cr.7310085, PII 7310085
    • D. Jiang, J. Liang, Y. Li, and P.W. Noble The role of Toll-like receptors in non-infectious lung injury Cell Res 16 2006 693 701 (Pubitemid 44258922)
    • (2006) Cell Research , vol.16 , Issue.8 , pp. 693-701
    • Jiang, D.1    Liang, J.2    Li, Y.3    Noble, P.W.4
  • 4
    • 35748965880 scopus 로고    scopus 로고
    • TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: Role of dendritic cells
    • U. Bhan, N.W. Lukacs, J.J. Osterholzer, M.W. Newstead, X. Zeng, and T.A. Moore TLR9 is required for protective innate immunity in Gram-negative bacterial pneumonia: role of dendritic cells J Immunol 179 2007 3937 3946
    • (2007) J Immunol , vol.179 , pp. 3937-3946
    • Bhan, U.1    Lukacs, N.W.2    Osterholzer, J.J.3    Newstead, M.W.4    Zeng, X.5    Moore, T.A.6
  • 5
    • 79251581880 scopus 로고    scopus 로고
    • Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo
    • H.S. Shin, F. Xu, A. Bagchi, E. Herrup, A. Prakash, and C. Valentine Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo J Immunol 186 2011 1119 1130
    • (2011) J Immunol , vol.186 , pp. 1119-1130
    • Shin, H.S.1    Xu, F.2    Bagchi, A.3    Herrup, E.4    Prakash, A.5    Valentine, C.6
  • 8
    • 0033168728 scopus 로고    scopus 로고
    • Cutting edge: Recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2
    • A. Yoshimura, E. Lien, R.R. Ingalls, E. Tuomanen, R. Dziarski, and D. Golenbock Cutting edge: recognition of Gram-positive bacterial cell wall components by the innate immune system occurs via Toll-like receptor 2 J Immunol 163 1999 1 5 (Pubitemid 29295815)
    • (1999) Journal of Immunology , vol.163 , Issue.1 , pp. 1-5
    • Yoshimura, A.1    Lien, E.2    Ingalls, R.R.3    Tuomanen, E.4    Dziarski, R.5    Golenbock, D.6
  • 9
    • 1342324587 scopus 로고    scopus 로고
    • Toll-Like Receptor 2 Plays a Role in the Early Inflammatory Response to Murine Pneumococcal Pneumonia but Does Not Contribute to Antibacterial Defense
    • S. Knapp, C.W. Wieland, C. van 't Veer, O. Takeuchi, S. Akira, and S. Florquin Toll-like receptor 2 plays a role in the early inflammatory response to murine pneumococcal pneumonia but does not contribute to antibacterial defense J Immunol 172 2004 3132 3138 (Pubitemid 38263703)
    • (2004) Journal of Immunology , vol.172 , Issue.5 , pp. 3132-3138
    • Knapp, S.1    Wieland, C.W.2    Van't Veer, C.3    Takeuchi, O.4    Akira, S.5    Florquin, S.6    Van Der Poll, T.7
  • 11
    • 1542617932 scopus 로고    scopus 로고
    • Cutting Edge: Myeloid Differentiation Factor 88 Is Essential for Pulmonary Host Defense against Pseudomonas aeruginosa but Not Staphylococcus aureus
    • S.J. Skerrett, H.D. Liggitt, A.M. Hajjar, and C.B. Wilson Cutting edge: myeloid differentiation factor 88 is essential for pulmonary host defense against Pseudomonas aeruginosa but not Staphylococcus aureus J Immunol 172 2004 3377 3381 (Pubitemid 38337914)
    • (2004) Journal of Immunology , vol.172 , Issue.6 , pp. 3377-3381
    • Skerrett, S.J.1    Liggitt, H.D.2    Hajjar, A.M.3    Wilson, C.B.4
  • 12
    • 79251555968 scopus 로고    scopus 로고
    • TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo
    • A. Zivkovic, O. Sharif, K. Stich, B. Doninger, M. Biaggio, and J. Colinge TLR 2 and CD14 mediate innate immunity and lung inflammation to staphylococcal Panton-Valentine leukocidin in vivo J Immunol 186 2011 1608 1617
    • (2011) J Immunol , vol.186 , pp. 1608-1617
    • Zivkovic, A.1    Sharif, O.2    Stich, K.3    Doninger, B.4    Biaggio, M.5    Colinge, J.6
  • 13
    • 11144292663 scopus 로고    scopus 로고
    • Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by gram-negative bacteria
    • DOI 10.1128/IAI.73.1.532-545.2005
    • J.R. Schurr, E. Young, P. Byrne, C. Steele, J.E. Shellito, and J.K. Kolls Central role of toll-like receptor 4 signaling and host defense in experimental pneumonia caused by Gram-negative bacteria Infect Immun 73 2005 532 545 (Pubitemid 40041148)
    • (2005) Infection and Immunity , vol.73 , Issue.1 , pp. 532-545
    • Schurr, J.R.1    Young, E.2    Byrne, P.3    Steele, C.4    Shellito, J.E.5    Kolls, J.K.6
  • 14
    • 79251583465 scopus 로고    scopus 로고
    • Cooperative interactions between TLR4 and TLR9 regulate interleukin 23 and 17 production in a murine model of gram negative bacterial pneumonia
    • U. Bhan, M.N. Ballinger, X. Zeng, M.J. Newstead, M.D. Cornicelli, and T.J. Standiford Cooperative interactions between TLR4 and TLR9 regulate interleukin 23 and 17 production in a murine model of gram negative bacterial pneumonia PLoS One 5 2010 e9896
    • (2010) PLoS One , vol.5 , pp. 9896
    • Bhan, U.1    Ballinger, M.N.2    Zeng, X.3    Newstead, M.J.4    Cornicelli, M.D.5    Standiford, T.J.6
  • 15
    • 27144528203 scopus 로고    scopus 로고
    • The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable Haemophilus influenzae from the mouse lung
    • C.W. Wieland, S. Florquin, N.A. Maris, K. Hoebe, B. Beutler, and K. Takeda The MyD88-dependent, but not the MyD88-independent, pathway of TLR4 signaling is important in clearing nontypeable haemophilus influenzae from the mouse lung J Immunol 175 2005 6042 6049 (Pubitemid 41508090)
    • (2005) Journal of Immunology , vol.175 , Issue.9 , pp. 6042-6049
    • Wieland, C.W.1    Florquin, S.2    Maris, N.A.3    Hoebe, K.4    Beutler, B.5    Takeda, K.6    Akira, S.7    Van Der Poll, T.8
  • 16
    • 33745316754 scopus 로고    scopus 로고
    • Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa
    • S. Jeyaseelan, S.K. Young, M. Yamamoto, P.G. Arndt, S. Akira, and J.K. Kolls Toll/IL-1R domain-containing adaptor protein (TIRAP) is a critical mediator of antibacterial defense in the lung against Klebsiella pneumoniae but not Pseudomonas aeruginosa J Immunol 177 2006 538 547 (Pubitemid 43939167)
    • (2006) Journal of Immunology , vol.177 , Issue.1 , pp. 538-547
    • Jeyaseelan, S.1    Young, S.K.2    Yamamoto, M.3    Arndt, P.G.4    Akira, S.5    Kolls, J.K.6    Worthen, G.S.7
  • 19
    • 77953316015 scopus 로고    scopus 로고
    • Both TRIF- and MyD88-dependent signaling contribute to host defense against pulmonary Klebsiella infection
    • S. Cai, S. Batra, L. Shen, N. Wakamatsu, and S. Jeyaseelan Both TRIF- and MyD88-dependent signaling contribute to host defense against pulmonary Klebsiella infection J Immunol 183 2009 6629 6638
    • (2009) J Immunol , vol.183 , pp. 6629-6638
    • Cai, S.1    Batra, S.2    Shen, L.3    Wakamatsu, N.4    Jeyaseelan, S.5
  • 21
    • 47949127946 scopus 로고    scopus 로고
    • Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin
    • R. Ramphal, V. Balloy, J. Jyot, A. Verma, M. Si-Tahar, and M. Chignard Control of Pseudomonas aeruginosa in the lung requires the recognition of either lipopolysaccharide or flagellin J Immunol 181 2008 586 592
    • (2008) J Immunol , vol.181 , pp. 586-592
    • Ramphal, R.1    Balloy, V.2    Jyot, J.3    Verma, A.4    Si-Tahar, M.5    Chignard, M.6
  • 22
    • 33646948879 scopus 로고    scopus 로고
    • MyD88-dependent responses involving Toll-like receptor 2 are important for protection and clearance of legionella pneumophila in a mouse model of Legionnaires' disease
    • DOI 10.1128/IAI.02049-05
    • K.A. Archer, and C.R. Roy MyD88-dependent responses involving toll-like receptor 2 are important for protection and clearance of Legionella pneumophila in a mouse model of Legionnaires' disease Infect Immun 74 2006 3325 3333 (Pubitemid 43794520)
    • (2006) Infection and Immunity , vol.74 , Issue.6 , pp. 3325-3333
    • Archer, K.A.1    Roy, C.R.2
  • 23
    • 58149295583 scopus 로고    scopus 로고
    • Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila
    • K.A. Archer, L. Alexopoulou, R.A. Flavell, and C.R. Roy Multiple MyD88-dependent responses contribute to pulmonary clearance of Legionella pneumophila Cell Microbiol 11 2009 21 36
    • (2009) Cell Microbiol , vol.11 , pp. 21-36
    • Archer, K.A.1    Alexopoulou, L.2    Flavell, R.A.3    Roy, C.R.4
  • 24
    • 46449125113 scopus 로고    scopus 로고
    • Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila
    • U. Bhan, G. Trujillo, K. Lyn-Kew, M.W. Newstead, X. Zeng, and C.M. Hogaboam Toll-like receptor 9 regulates the lung macrophage phenotype and host immunity in murine pneumonia caused by Legionella pneumophila Infect Immun 76 2008 2895 2904
    • (2008) Infect Immun , vol.76 , pp. 2895-2904
    • Bhan, U.1    Trujillo, G.2    Lyn-Kew, K.3    Newstead, M.W.4    Zeng, X.5    Hogaboam, C.M.6
  • 29
    • 66349097787 scopus 로고    scopus 로고
    • The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection
    • K. Shimada, S. Chen, P.W. Dempsey, R. Sorrentino, R. Alsabeh, and A.V. Slepenkin The NOD/RIP2 pathway is essential for host defenses against Chlamydophila pneumoniae lung infection PLoS Pathog 5 2009 e1000379
    • (2009) PLoS Pathog , vol.5 , pp. 1000379
    • Shimada, K.1    Chen, S.2    Dempsey, P.W.3    Sorrentino, R.4    Alsabeh, R.5    Slepenkin, A.V.6
  • 30
    • 77956281883 scopus 로고    scopus 로고
    • Toll-like receptor 2 (TLR2) plays a major role in innate resistance in the lung against murine Mycoplasma
    • W. Love, N. Dobbs, L. Tabor, and J.W. Simecka Toll-like receptor 2 (TLR2) plays a major role in innate resistance in the lung against murine Mycoplasma PLoS One 5 2010 e10739
    • (2010) PLoS One , vol.5 , pp. 10739
    • Love, W.1    Dobbs, N.2    Tabor, L.3    Simecka, J.W.4
  • 31
    • 77952993918 scopus 로고    scopus 로고
    • Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: An observational study in three cohorts
    • O. Kumpf, E.J. Giamarellos-Bourboulis, A. Koch, L. Hamann, M. Mouktaroudi, and D.Y. Oh Influence of genetic variations in TLR4 and TIRAP/Mal on the course of sepsis and pneumonia and cytokine release: an observational study in three cohorts Crit Care 14 2010 R103
    • (2010) Crit Care , vol.14 , pp. 103
    • Kumpf, O.1    Giamarellos-Bourboulis, E.J.2    Koch, A.3    Hamann, L.4    Mouktaroudi, M.5    Oh, D.Y.6
  • 32
    • 38449115675 scopus 로고    scopus 로고
    • Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila
    • T.R. Hawn, W.R. Berrington, I.A. Smith, S. Uematsu, S. Akira, and A. Aderem Altered inflammatory responses in TLR5-deficient mice infected with Legionella pneumophila J Immunol 179 2007 6981 6987
    • (2007) J Immunol , vol.179 , pp. 6981-6987
    • Hawn, T.R.1    Berrington, W.R.2    Smith, I.A.3    Uematsu, S.4    Akira, S.5    Aderem, A.6
  • 33
    • 27744448143 scopus 로고    scopus 로고
    • Innate immunity to mycobacterial infection in mice: Critical role for toll-like receptors
    • DOI 10.1016/j.tube.2005.08.021, PII S147297920500065X
    • B. Ryffel, C. Fremond, M. Jacobs, S. Parida, T. Botha, and B. Schnyder Innate immunity to mycobacterial infection in mice: critical role for toll-like receptors Tuberculosis (Edinb) 85 2005 395 405 (Pubitemid 41617394)
    • (2005) Tuberculosis , vol.85 , Issue.5-6 , pp. 395-405
    • Ryffel, B.1    Fremond, C.2    Jacobs, M.3    Parida, S.4    Botha, T.5    Schnyder, B.6    Quesniaux, V.7
  • 35
    • 61749095416 scopus 로고    scopus 로고
    • TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4
    • T. Ito, M. Schaller, C.M. Hogaboam, T.J. Standiford, M. Sandor, and N.W. Lukacs TLR9 regulates the mycobacteria-elicited pulmonary granulomatous immune response in mice through DC-derived Notch ligand delta-like 4 J Clin Invest 119 2009 33 46
    • (2009) J Clin Invest , vol.119 , pp. 33-46
    • Ito, T.1    Schaller, M.2    Hogaboam, C.M.3    Standiford, T.J.4    Sandor, M.5    Lukacs, N.W.6
  • 36
    • 70049094025 scopus 로고    scopus 로고
    • NOD2, RIP2 and IRF5 play a critical role in the type i interferon response to Mycobacterium tuberculosis
    • A.K. Pandey, Y. Yang, Z. Jiang, S.M. Fortune, F. Coulombe, and M.A. Behr NOD2, RIP2 and IRF5 play a critical role in the type I interferon response to Mycobacterium tuberculosis PLoS Pathog 5 2009 e1000500
    • (2009) PLoS Pathog , vol.5 , pp. 1000500
    • Pandey, A.K.1    Yang, Y.2    Jiang, Z.3    Fortune, S.M.4    Coulombe, F.5    Behr, M.A.6
  • 37
    • 16644364418 scopus 로고    scopus 로고
    • Interactions of Toll-like receptors with fungi
    • DOI 10.1016/j.micinf.2004.08.014
    • S.M. Levitz Interactions of Toll-like receptors with fungi Microbes Infect 6 2004 1351 1355 (Pubitemid 41110576)
    • (2004) Microbes and Infection , vol.6 , Issue.15 , pp. 1351-1355
    • Levitz, S.M.1
  • 41
    • 33748178805 scopus 로고    scopus 로고
    • TLR2, but not TLR4, triggers cytokine production by murine cells in response to Candida albicans yeasts and hyphae
    • DOI 10.1016/j.micinf.2006.03.014, PII S1286457906001900
    • M.L. Gil, and D. Gozalbo TLR2, but not TLR4, triggers cytokine production by murine cells in response to Candida albicans yeasts and hyphae Microbes Infect 8 2006 2299 2304 (Pubitemid 44311598)
    • (2006) Microbes and Infection , vol.8 , Issue.8 , pp. 2299-2304
    • Gil, M.L.1    Gozalbo, D.2
  • 43
    • 77957285801 scopus 로고    scopus 로고
    • TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs
    • Y. Zhang, F. Wang, U. Bhan, G.B. Huffnagle, G.B. Toews, and T.J. Standiford TLR9 signaling is required for generation of the adaptive immune protection in Cryptococcus neoformans-infected lungs Am J Pathol 177 2010 754 765
    • (2010) Am J Pathol , vol.177 , pp. 754-765
    • Zhang, Y.1    Wang, F.2    Bhan, U.3    Huffnagle, G.B.4    Toews, G.B.5    Standiford, T.J.6
  • 44
    • 15244342214 scopus 로고    scopus 로고
    • Impaired recognition by Toll-like receptor 4 is responsible for exacerbated murine Pneumocystis pneumonia
    • DOI 10.1016/j.micinf.2004.10.010
    • K. Ding, A. Shibui, Y. Wang, M. Takamoto, T. Matsuguchi, and K. Sugane Impaired recognition by Toll-like receptor 4 is responsible for exacerbated murine Pneumocystis pneumonia Microbes Infect 7 2005 195 203 (Pubitemid 40387423)
    • (2005) Microbes and Infection , vol.7 , Issue.2 , pp. 195-203
    • Ding, K.1    Shibui, A.2    Wang, Y.3    Takamoto, M.4    Matsuguchi, T.5    Sugane, K.6
  • 45
    • 42649116405 scopus 로고    scopus 로고
    • Decreased inflammatory response in Toll-like receptor 2 knockout mice is associated with exacerbated Pneumocystis pneumonia
    • S.H. Wang, C. Zhang, M.E. Lasbury, C.P. Liao, P.J. Durant, and D. Tschang Decreased inflammatory response in Toll-like receptor 2 knockout mice is associated with exacerbated Pneumocystis pneumonia Microbes Infect 10 2008 334 341
    • (2008) Microbes Infect , vol.10 , pp. 334-341
    • Wang, S.H.1    Zhang, C.2    Lasbury, M.E.3    Liao, C.P.4    Durant, P.J.5    Tschang, D.6
  • 46
    • 33646049347 scopus 로고    scopus 로고
    • Innate sensing of self and non-self RNAs by Toll-like receptors
    • M. Sioud Innate sensing of self and non-self RNAs by Toll-like receptors Trends Mol Med 12 2006 167 176
    • (2006) Trends Mol Med , vol.12 , pp. 167-176
    • Sioud, M.1
  • 48
    • 1542317550 scopus 로고    scopus 로고
    • Innate Antiviral Responses by Means of TLR7-Mediated Recognition of Single-Stranded RNA
    • DOI 10.1126/science.1093616
    • S.S. Diebold, T. Kaisho, H. Hemmi, S. Akira, and C. Reis e Sousa Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA Science 303 2004 1529 1531 (Pubitemid 38314425)
    • (2004) Science , vol.303 , Issue.5663 , pp. 1529-1531
    • Diebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reis E Sousa, C.5
  • 49
    • 38949117752 scopus 로고    scopus 로고
    • Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination
    • S. Koyama, K.J. Ishii, H. Kumar, T. Tanimoto, C. Coban, and S. Uematsu Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination J Immunol 179 2007 4711 4720
    • (2007) J Immunol , vol.179 , pp. 4711-4720
    • Koyama, S.1    Ishii, K.J.2    Kumar, H.3    Tanimoto, T.4    Coban, C.5    Uematsu, S.6
  • 50
    • 77952534501 scopus 로고    scopus 로고
    • Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model
    • M.S. Boukhvalova, T.B. Sotomayor, R.C. Point, L.M. Pletneva, G.A. Prince, and J.C. Blanco Activation of interferon response through toll-like receptor 3 impacts viral pathogenesis and pulmonary toll-like receptor expression during respiratory syncytial virus and influenza infections in the cotton rat Sigmodon hispidus model J Interferon Cytokine Res 30 2010 229 242
    • (2010) J Interferon Cytokine Res , vol.30 , pp. 229-242
    • Boukhvalova, M.S.1    Sotomayor, T.B.2    Point, R.C.3    Pletneva, L.M.4    Prince, G.A.5    Blanco, J.C.6
  • 51
    • 78650642085 scopus 로고    scopus 로고
    • Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type i IFN-dependent fashion
    • J. Wei, J. Waithman, R. Lata, N.A. Mifsud, J. Cebon, and T. Kay Influenza A infection enhances cross-priming of CD8+ T cells to cell-associated antigens in a TLR7- and type I IFN-dependent fashion J Immunol 185 2010 6013 6022
    • (2010) J Immunol , vol.185 , pp. 6013-6022
    • Wei, J.1    Waithman, J.2    Lata, R.3    Mifsud, N.A.4    Cebon, J.5    Kay, T.6
  • 52
    • 33745684282 scopus 로고    scopus 로고
    • Detrimental contribution of the Toll-like receptor (TLR) 3 to influenza A virus-induced acute pneumonia
    • R. Le Goffic, V. Balloy, M. Lagranderie, L. Alexopoulou, N. Escriou, and R. Flavell Detrimental contribution of the Toll-like receptor (TLR) 3 to influenza A virus-induced acute pneumonia PLoS Pathog 2 2006 e53
    • (2006) PLoS Pathog , vol.2 , pp. 53
    • Le Goffic, R.1    Balloy, V.2    Lagranderie, M.3    Alexopoulou, L.4    Escriou, N.5    Flavell, R.6
  • 53
    • 59749092826 scopus 로고    scopus 로고
    • Respiratory syncytial virus activates innate immunity through Toll-like receptor 2
    • M.R. Murawski, G.N. Bowen, A.M. Cerny, L.J. Anderson, L.M. Haynes, and R.A. Tripp Respiratory syncytial virus activates innate immunity through Toll-like receptor 2 J Virol 83 2009 1492 1500
    • (2009) J Virol , vol.83 , pp. 1492-1500
    • Murawski, M.R.1    Bowen, G.N.2    Cerny, A.M.3    Anderson, L.J.4    Haynes, L.M.5    Tripp, R.A.6
  • 54
  • 56
    • 64149087970 scopus 로고    scopus 로고
    • House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
    • H. Hammad, M. Chieppa, F. Perros, M.A. Willart, R.N. Germain, and B.N. Lambrecht House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells Nat Med 15 2009 410 416
    • (2009) Nat Med , vol.15 , pp. 410-416
    • Hammad, H.1    Chieppa, M.2    Perros, F.3    Willart, M.A.4    Germain, R.N.5    Lambrecht, B.N.6
  • 57
    • 77956198120 scopus 로고    scopus 로고
    • Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: Implication of airway epithelium and dendritic cells
    • D. Torres, A. Dieudonne, B. Ryffel, E. Vilain, M. Si-Tahar, and M. Pichavant Double-stranded RNA exacerbates pulmonary allergic reaction through TLR3: implication of airway epithelium and dendritic cells J Immunol 185 2010 451 459
    • (2010) J Immunol , vol.185 , pp. 451-459
    • Torres, D.1    Dieudonne, A.2    Ryffel, B.3    Vilain, E.4    Si-Tahar, M.5    Pichavant, M.6
  • 58
    • 79551468701 scopus 로고    scopus 로고
    • Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs
    • E.H. Kaufman, A.D. Fryer, and D.B. Jacoby Toll-like receptor 7 agonists are potent and rapid bronchodilators in guinea pigs J Allergy Clin Immunol 127 2011 462 469
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 462-469
    • Kaufman, E.H.1    Fryer, A.D.2    Jacoby, D.B.3
  • 59
    • 77954754177 scopus 로고    scopus 로고
    • Toll-like receptor 7-triggered immune response in the lung mediates acute and long-lasting suppression of experimental asthma
    • C. Xirakia, O. Koltsida, A. Stavropoulos, A. Thanassopoulou, V. Aidinis, and P. Sideras Toll-like receptor 7-triggered immune response in the lung mediates acute and long-lasting suppression of experimental asthma Am J Respir Crit Care Med 181 2010 1207 1216
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. 1207-1216
    • Xirakia, C.1    Koltsida, O.2    Stavropoulos, A.3    Thanassopoulou, A.4    Aidinis, V.5    Sideras, P.6
  • 60
    • 58549116357 scopus 로고    scopus 로고
    • Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma
    • Q. Du, L.F. Zhou, Z. Chen, X.Y. Gu, M. Huang, and K.S. Yin Imiquimod, a toll-like receptor 7 ligand, inhibits airway remodelling in a murine model of chronic asthma Clin Exp Pharmacol Physiol 36 2009 43 48
    • (2009) Clin Exp Pharmacol Physiol , vol.36 , pp. 43-48
    • Du, Q.1    Zhou, L.F.2    Chen, Z.3    Gu, X.Y.4    Huang, M.5    Yin, K.S.6
  • 61
    • 0037237628 scopus 로고    scopus 로고
    • Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: Dependency on antigen dose and differential toll-like receptor ligation
    • DOI 10.1084/jem.20021908
    • A. Boonstra, C. Asselin-Paturel, M. Gilliet, C. Crain, G. Trinchieri, and Y.J. Liu Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation J Exp Med 197 2003 101 109 (Pubitemid 36110261)
    • (2003) Journal of Experimental Medicine , vol.197 , Issue.1 , pp. 101-109
    • Boonstra, A.1    Asselin-Paturel, C.2    Gilliet, M.3    Crain, C.4    Trinchieri, G.5    Liu, Y.-J.6    O'Garra, A.7
  • 63
    • 61749093073 scopus 로고    scopus 로고
    • Use of CpG oligonucleotides in treatment of asthma and allergic disease
    • D.E. Fonseca, and J.N. Kline Use of CpG oligonucleotides in treatment of asthma and allergic disease Adv Drug Deliv Rev 61 2009 256 262
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 256-262
    • Fonseca, D.E.1    Kline, J.N.2
  • 64
    • 77954589298 scopus 로고    scopus 로고
    • CpG oligodeoxynucleotides as TLR9 agonists: Therapeutic application in allergy and asthma
    • G.K. Gupta, and D.K. Agrawal CpG oligodeoxynucleotides as TLR9 agonists: therapeutic application in allergy and asthma BioDrugs 24 2010 225 235
    • (2010) BioDrugs , vol.24 , pp. 225-235
    • Gupta, G.K.1    Agrawal, D.K.2
  • 67
    • 79551671642 scopus 로고    scopus 로고
    • Genetic variations in toll-like receptor pathway genes influence asthma and atopy
    • R. Tesse, R.C. Pandey, and M. Kabesch Genetic variations in toll-like receptor pathway genes influence asthma and atopy Allergy 66 2011 307 316
    • (2011) Allergy , vol.66 , pp. 307-316
    • Tesse, R.1    Pandey, R.C.2    Kabesch, M.3
  • 68
    • 40449118020 scopus 로고    scopus 로고
    • Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent
    • E. Doz, N. Noulin, E. Boichot, I. Guenon, L. Fick, and M. Le Bert Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent J Immunol 180 2008 1169 1178
    • (2008) J Immunol , vol.180 , pp. 1169-1178
    • Doz, E.1    Noulin, N.2    Boichot, E.3    Guenon, I.4    Fick, L.5    Le Bert, M.6
  • 69
    • 33745483812 scopus 로고    scopus 로고
    • Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages
    • K. Karimi, H. Sarir, E. Mortaz, J.J. Smit, H. Hosseini, and S.J. De Kimpe Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages Respir Res 7 2006 66
    • (2006) Respir Res , vol.7 , pp. 66
    • Karimi, K.1    Sarir, H.2    Mortaz, E.3    Smit, J.J.4    Hosseini, H.5    De Kimpe, S.J.6
  • 70
    • 78650177220 scopus 로고    scopus 로고
    • TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure
    • E. Pace, A. Giarratano, M. Ferraro, A. Bruno, L. Siena, and S. Mangione TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure Hum Immunol 72 2011 54 62
    • (2011) Hum Immunol , vol.72 , pp. 54-62
    • Pace, E.1    Giarratano, A.2    Ferraro, M.3    Bruno, A.4    Siena, L.5    Mangione, S.6
  • 71
    • 0842321777 scopus 로고    scopus 로고
    • Involvement of Reactive Oxygen Species in Toll-Like Receptor 4-Dependent Activation of NF-κB
    • K. Asehnoune, D. Strassheim, S. Mitra, J.Y. Kim, and E. Abraham Involvement of reactive oxygen species in Toll-like receptor 4-dependent activation of NF-kappa B J Immunol 172 2004 2522 2529 (Pubitemid 38182403)
    • (2004) Journal of Immunology , vol.172 , Issue.4 , pp. 2522-2529
    • Asehnoune, K.1    Strassheim, D.2    Mitra, S.3    Kim, J.Y.4    Abraham, E.5
  • 73
  • 75
    • 38349190718 scopus 로고    scopus 로고
    • Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke
    • R.E. MacRedmond, C.M. Greene, D.R. Dorscheid, N.G. McElvaney, and S.J. O'Neill Epithelial expression of TLR4 is modulated in COPD and by steroids, salmeterol and cigarette smoke Respir Res 8 2007 84
    • (2007) Respir Res , vol.8 , pp. 84
    • MacRedmond, R.E.1    Greene, C.M.2    Dorscheid, D.R.3    McElvaney, N.G.4    O'Neill, S.J.5
  • 77
    • 69749097391 scopus 로고    scopus 로고
    • Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation
    • E. Mortaz, Z. Lazar, L. Koenderman, A.D. Kraneveld, F.P. Nijkamp, and G. Folkerts Cigarette smoke attenuates the production of cytokines by human plasmacytoid dendritic cells and enhances the release of IL-8 in response to TLR-9 stimulation Respir Res 10 2009 47
    • (2009) Respir Res , vol.10 , pp. 47
    • Mortaz, E.1    Lazar, Z.2    Koenderman, L.3    Kraneveld, A.D.4    Nijkamp, F.P.5    Folkerts, G.6
  • 81
    • 12444322678 scopus 로고    scopus 로고
    • TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells
    • C.M. Greene, T.P. Carroll, S.G. Smith, C.C. Taggart, J. Devaney, and S. Griffin TLR-induced inflammation in cystic fibrosis and non-cystic fibrosis airway epithelial cells J Immunol 174 2005 1638 1646
    • (2005) J Immunol , vol.174 , pp. 1638-1646
    • Greene, C.M.1    Carroll, T.P.2    Smith, S.G.3    Taggart, C.C.4    Devaney, J.5    Griffin, S.6
  • 82
    • 53149151884 scopus 로고    scopus 로고
    • TLR expression on neutrophils at the pulmonary site of infection: TLR1/TLR2-mediated up-regulation of TLR5 expression in cystic fibrosis lung disease
    • B. Koller, M. Kappler, P. Latzin, A. Gaggar, M. Schreiner, and S. Takyar TLR expression on neutrophils at the pulmonary site of infection: TLR1/TLR2-mediated up-regulation of TLR5 expression in cystic fibrosis lung disease J Immunol 181 2008 2753 2763
    • (2008) J Immunol , vol.181 , pp. 2753-2763
    • Koller, B.1    Kappler, M.2    Latzin, P.3    Gaggar, A.4    Schreiner, M.5    Takyar, S.6
  • 83
    • 47249131603 scopus 로고    scopus 로고
    • Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease
    • C.J. Blohmke, R.E. Victor, A.F. Hirschfeld, I.M. Elias, D.G. Hancock, and C.R. Lane Innate immunity mediated by TLR5 as a novel antiinflammatory target for cystic fibrosis lung disease J Immunol 180 2008 7764 7773
    • (2008) J Immunol , vol.180 , pp. 7764-7773
    • Blohmke, C.J.1    Victor, R.E.2    Hirschfeld, A.F.3    Elias, I.M.4    Hancock, D.G.5    Lane, C.R.6
  • 84
    • 33645770464 scopus 로고    scopus 로고
    • Inducible activation of TLR4 confers resistance to hyperoxia-induced pulmonary apoptosis
    • S.T. Qureshi, X. Zhang, E. Aberg, N. Bousette, A. Giaid, and P. Shan Inducible activation of TLR4 confers resistance to hyperoxia-induced pulmonary apoptosis J Immunol 176 2006 4950 4958
    • (2006) J Immunol , vol.176 , pp. 4950-4958
    • Qureshi, S.T.1    Zhang, X.2    Aberg, E.3    Bousette, N.4    Giaid, A.5    Shan, P.6
  • 88
    • 33746847261 scopus 로고    scopus 로고
    • Surfactant protein A directly interacts with TLR4 and MD-2 and regulates inflammatory cellular response: Importance of supratrimeric oligomerization
    • DOI 10.1074/jbc.M513041200
    • C. Yamada, H. Sano, T. Shimizu, H. Mitsuzawa, C. Nishitani, and T. Himi Surfactant protein A directly interacts with TLR4 and MD-2 and regulates inflammatory cellular response. Importance of supratrimeric oligomerization J Biol Chem 281 2006 21771 21780 (Pubitemid 44181881)
    • (2006) Journal of Biological Chemistry , vol.281 , Issue.31 , pp. 21771-21780
    • Yamada, C.1    Sano, H.2    Shimizu, T.3    Mitsuzawa, H.4    Nishitani, C.5    Himi, T.6    Kuroki, Y.7
  • 92
    • 33847361903 scopus 로고    scopus 로고
    • Infectious disease, the innate immune response, and fibrosis
    • DOI 10.1172/JCI30595
    • A. Meneghin, and C.M. Hogaboam Infectious disease, the innate immune response, and fibrosis J Clin Invest 117 2007 530 538 (Pubitemid 46348507)
    • (2007) Journal of Clinical Investigation , vol.117 , Issue.3 , pp. 530-538
    • Meneghin, A.1    Hogaboam, C.M.2
  • 94
    • 54049116619 scopus 로고    scopus 로고
    • TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation
    • A. Meneghin, E.S. Choi, H.L. Evanoff, S.L. Kunkel, F.J. Martinez, and K.R. Flaherty TLR9 is expressed in idiopathic interstitial pneumonia and its activation promotes in vitro myofibroblast differentiation Histochem Cell Biol 130 2008 979 992
    • (2008) Histochem Cell Biol , vol.130 , pp. 979-992
    • Meneghin, A.1    Choi, E.S.2    Evanoff, H.L.3    Kunkel, S.L.4    Martinez, F.J.5    Flaherty, K.R.6
  • 98
    • 72549098662 scopus 로고    scopus 로고
    • Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation
    • T. Ito, M. Schaller, T. Raymond, A.D. Joshi, A.L. Coelho, and F.G. Frantz Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation Am J Respir Crit Care Med 180 2009 1227 1238
    • (2009) Am J Respir Crit Care Med , vol.180 , pp. 1227-1238
    • Ito, T.1    Schaller, M.2    Raymond, T.3    Joshi, A.D.4    Coelho, A.L.5    Frantz, F.G.6
  • 99
    • 59449103610 scopus 로고    scopus 로고
    • Higher monocyte expression of TLR2 and TLR4, and enhanced pro-inflammatory synergy of TLR2 with NOD2 stimulation in sarcoidosis
    • M. Wiken, J. Grunewald, A. Eklund, and J. Wahlstrom Higher monocyte expression of TLR2 and TLR4, and enhanced pro-inflammatory synergy of TLR2 with NOD2 stimulation in sarcoidosis J Clin Immunol 29 2009 78 89
    • (2009) J Clin Immunol , vol.29 , pp. 78-89
    • Wiken, M.1    Grunewald, J.2    Eklund, A.3    Wahlstrom, J.4
  • 100
    • 79551595151 scopus 로고    scopus 로고
    • No evidence of altered alveolar macrophage polarization, but reduced expression of TLR2, in bronchoalveolar lavage cells in sarcoidosis
    • M. Wiken, F. Idali, M.A. Al Hayja, J. Grunewald, A. Eklund, and J. Wahlstrom No evidence of altered alveolar macrophage polarization, but reduced expression of TLR2, in bronchoalveolar lavage cells in sarcoidosis Respir Res 11 2010 121
    • (2010) Respir Res , vol.11 , pp. 121
    • Wiken, M.1    Idali, F.2    Al Hayja, M.A.3    Grunewald, J.4    Eklund, A.5    Wahlstrom, J.6
  • 104
    • 33745956445 scopus 로고    scopus 로고
    • Toll-like receptor (TLR) 4 polymorphism Asp299Gly is not associated with disease course in Dutch sarcoidosis patients
    • DOI 10.1111/j.1365-2249.2006.03127.x
    • M. Veltkamp, J.C. Grutters, C.H. van Moorsel, H.J. Ruven, and J.M. van den Bosch Toll-like receptor (TLR) 4 polymorphism Asp299Gly is not associated with disease course in Dutch sarcoidosis patients Clin Exp Immunol 145 2006 215 218 (Pubitemid 44060110)
    • (2006) Clinical and Experimental Immunology , vol.145 , Issue.2 , pp. 215-218
    • Veltkamp, M.1    Grutters, J.C.2    Van Moorsel, C.H.M.3    Ruven, H.J.T.4    Van Den Bosch, J.M.M.5
  • 107
    • 0030962332 scopus 로고    scopus 로고
    • Interferon-γ is necessary for the expression of hypersensitivity pneumonitis
    • G. Gudmundsson, and G.W. Hunninghake Interferon-gamma is necessary for the expression of hypersensitivity pneumonitis J Clin Invest 99 1997 2386 2390 (Pubitemid 27227715)
    • (1997) Journal of Clinical Investigation , vol.99 , Issue.10 , pp. 2386-2390
    • Gudmundsson, G.1    Hunninghake, G.W.2
  • 108
    • 20844454248 scopus 로고    scopus 로고
    • IFN-γ production by innate immune cells is sufficient for development of hypersensitivity pneumonitis
    • DOI 10.1002/eji.200425762
    • S. Nance, R. Cross, A.K. Yi, and E.A. Fitzpatrick IFN-gamma production by innate immune cells is sufficient for development of hypersensitivity pneumonitis Eur J Immunol 35 2005 1928 1938 (Pubitemid 40862341)
    • (2005) European Journal of Immunology , vol.35 , Issue.6 , pp. 1928-1938
    • Nance, S.1    Cross, R.2    Yi, A.K.3    Fitzpatrick, E.A.4
  • 109
    • 46949094011 scopus 로고    scopus 로고
    • MyD88 is necessary for neutrophil recruitment in hypersensitivity pneumonitis
    • DOI 10.1189/jlb.0607391
    • S.C. Nance, A.K. Yi, F.C. Re, and E.A. Fitzpatrick MyD88 is necessary for neutrophil recruitment in hypersensitivity pneumonitis J Leukoc Biol 83 2008 1207 1217 (Pubitemid 351960353)
    • (2008) Journal of Leukocyte Biology , vol.83 , Issue.5 , pp. 1207-1217
    • Nance, S.C.1    Yi, A.-K.2    Re, F.C.3    Fitzpatrick, E.A.4
  • 111
    • 59849115870 scopus 로고    scopus 로고
    • Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis
    • P.L. Simonian, C.L. Roark, F. Wehrmann, A.K. Lanham, F. Diaz del Valle, and W.K. Born Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis J Immunol 182 2009 657 665
    • (2009) J Immunol , vol.182 , pp. 657-665
    • Simonian, P.L.1    Roark, C.L.2    Wehrmann, F.3    Lanham, A.K.4    Diaz Del Valle, F.5    Born, W.K.6
  • 112
    • 77950504533 scopus 로고    scopus 로고
    • Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis
    • D.J. Fong, C.M. Hogaboam, Y. Matsuno, S. Akira, S. Uematsu, and A.D. Joshi Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis Immunology 130 2010 125 136
    • (2010) Immunology , vol.130 , pp. 125-136
    • Fong, D.J.1    Hogaboam, C.M.2    Matsuno, Y.3    Akira, S.4    Uematsu, S.5    Joshi, A.D.6
  • 113
    • 77956821630 scopus 로고    scopus 로고
    • Th2-biased immune responses are important in a murine model of chronic hypersensitivity pneumonitis
    • K. Mitaka, Y. Miyazaki, M. Yasui, M. Furuie, S. Miyake, and N. Inase Th2-biased immune responses are important in a murine model of chronic hypersensitivity pneumonitis Int Arch Allergy Immunol 154 2011 264 274
    • (2011) Int Arch Allergy Immunol , vol.154 , pp. 264-274
    • Mitaka, K.1    Miyazaki, Y.2    Yasui, M.3    Furuie, M.4    Miyake, S.5    Inase, N.6
  • 115
    • 77954332995 scopus 로고    scopus 로고
    • Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population
    • N. Najmi, G. Kaur, S.K. Sharma, and N.K. Mehra Human Toll-like receptor 4 polymorphisms TLR4 Asp299Gly and Thr399Ile influence susceptibility and severity of pulmonary tuberculosis in the Asian Indian population Tissue Antigens 76 2010 102 109
    • (2010) Tissue Antigens , vol.76 , pp. 102-109
    • Najmi, N.1    Kaur, G.2    Sharma, S.K.3    Mehra, N.K.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.