TLR4 upregulation underpins airway neutrophilia in smokers with chronic obstructive pulmonary disease and acute respiratory failure

Human Immunology

Volumn 72, Issue 1, 2011, Pages 54-62

  Pace, Elisabetta ^a   Giarratano, Antonino ^b   Ferraro, Maria ^a,b   Bruno, Andreina ^a   Siena, Liboria ^a   Mangione, Salvatore ^b   Johnson, Malcolm ^c   Gjomarkaj, Mark ^a  

^a CNR   (Italy)

^b UNIVERSITY OF PALERMO   (Italy)

^c GLAXOSMITHKLINE   (United Kingdom)

Author keywords

Chemokines; Neutrophils; Respiratory failure; Toll like receptors

Indexed keywords

BETA DEFENSIN 2; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERLEUKIN 8; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4;

ACUTE RESPIRATORY FAILURE; AGED; APOPTOSIS; ARTICLE; ARTIFICIAL VENTILATION; CHRONIC OBSTRUCTIVE LUNG DISEASE; CLINICAL ARTICLE; CLINICAL ASSESSMENT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; HOST RESISTANCE; HUMAN; IMMUNE RESPONSE; IMMUNOCYTOCHEMISTRY; INTUBATION; LUNG LAVAGE; LYMPHOCYTE; MALE; NEUTROPHIL; NEUTROPHILIA; NICK END LABELING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACUTE DISEASE; AGED; AGED, 80 AND OVER; APOPTOSIS; BETA-DEFENSINS; BRONCHOALVEOLAR LAVAGE FLUID; CHEMOTAXIS; FEMALE; HUMANS; INTERLEUKIN-8; LEUKOCYTOSIS; MALE; NEUTROPHILS; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; RESPIRATORY INSUFFICIENCY; SMOKING; TOLL-LIKE RECEPTOR 2; TOLL-LIKE RECEPTOR 4;

EID: 78650177220     PISSN: 01988859     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.humimm.2010.09.009     Document Type: Article

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