Toll-like receptor 9 activation is a key mechanism for the maintenance of chronic lung inflammation

American Journal of Respiratory and Critical Care Medicine

Volumn 180, Issue 12, 2009, Pages 1227-1238

  Ito, Toshihiro ^a   Schaller, Matthew ^a   Raymond, Tracy ^a   Joshi, Amrita D ^a   Coelho, Ana L ^a   Frantz, Fabiani G ^a   Carson IV, William F ^a   Hogaboam, Cory M ^a   Lukacs, Nicholas W ^a   Standiford, Theodore J ^b   Phan, Sem H ^a   Chensue, Stephen W ^a,c   Kunkel, Steven L ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^c VA ANN ARBOR HEALTHCARE SYSTEM   (United States)

Author keywords

Dendritic cell; Granuloma; Innate immunity; Macrophage; Pulmonary fibrosis

Indexed keywords

ARGINASE 1; COLLAGEN; FOUND IN INFLAMMATORY ZONE 1; GAMMA INTERFERON; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 4; INTERLEUKIN 5; MESSENGER RNA; RECOMBINANT PROTEIN; SIGNAL PEPTIDE; TOLL LIKE RECEPTOR 9; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ADOPTIVE TRANSFER; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN EXPRESSION; ANTIGEN PRESENTING CELL; ARTICLE; BONE MARROW CELL; CD4+ T LYMPHOCYTE; CELL COUNT; CHRONIC INFLAMMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DRUG MECHANISM; FLOW CYTOMETRY; GENE EXPRESSION; IMMUNE RESPONSE; LUNG GRANULOMA; MACROPHAGE; MALE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SCHISTOSOMA MANSONI; TH2 CELL;

ANIMALS; CHRONIC DISEASE; DENDRITIC CELLS; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; GRANULOMA, RESPIRATORY TRACT; INFLAMMATION; LUNG; MALE; MICE; MICE, INBRED BALB C; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SCHISTOSOMA MANSONI; TOLL-LIKE RECEPTOR 9;

EID: 72549098662     PISSN: 1073449X     EISSN: 15354970     Source Type: Journal    
DOI: 10.1164/rccm.200906-0892OC     Document Type: Article

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