Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo

Journal of Immunology

Volumn 186, Issue 2, 2011, Pages 1119-1130

  Shin, Hae Sook ^a,b   Xu, Fengyun ^c   Bagchi, Aranya ^a,b   Herrup, Elizabeth ^d   Prakash, Arun ^c   Valentine, Catherine ^e   Kulkarni, Hrishikesh ^c   Wilhelmsen, Kevin ^c   Warren, Shaw ^a,b   Hellman, Judith ^c  

^a MASSACHUSETTS GENERAL HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF MASSACHUSETTS   (United States)

^e BOSTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL PROTEIN; ENDOTHELIAL LEUKOCYTE ADHESION MOLECULE 1; INTERLEUKIN 6; INTERLEUKIN 8; LIPOPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; PADGEM PROTEIN; PLASMINOGEN ACTIVATOR INHIBITOR 1; THROMBOPLASTIN; TISSUE FACTOR PATHWAY INHIBITOR; TOLL LIKE RECEPTOR 2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD CLOTTING; BLOOD CLOTTING DISORDER; CELL ADHESION; CELL PERMEABILIZATION; CYTOKINE PRODUCTION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ESCHERICHIA COLI; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IN VITRO STUDY; IN VIVO STUDY; LEUKOCYTE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; SEPSIS; UMBILICAL VEIN ENDOTHELIAL CELL;

ANIMALS; ANTICOAGULANTS; BLOOD COAGULATION; CAPILLARY PERMEABILITY; CELL LINE; ENDOTHELIUM, VASCULAR; ESCHERICHIA COLI PROTEINS; HUMANS; IMMUNOPHENOTYPING; LIPOPROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDOGLYCAN; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 2; UP-REGULATION;

EID: 79251581880     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1001647     Document Type: Article

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