Toll-like receptor 6 drives interleukin-17A expression during experimental hypersensitivity pneumonitis

Immunology

Volumn 130, Issue 1, 2010, Pages 125-136

  Fong, Daniel J ^a   Hogaboam, Cory M ^a   Matsuno, Yosuke ^a   Akira, Shizuo ^b   Uematsu, Satoshi ^b   Joshi, Amrita D ^a  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b OSAKA UNIVERSITY   (Japan)

Author keywords

Hypersensitivity pneumonitis; Interleukin 17A; Toll like receptor 6

Indexed keywords

BACTERIAL ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; RANTES; SACCHAROPOLYSPORA RECTIVIRGULA ANTIGEN; TOLL LIKE RECEPTOR 6; UNCLASSIFIED DRUG;

ALLERGIC PNEUMONITIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN FUNCTION; ARTICLE; C57BL 6 MOUSE; CD4 CD8 RATIO; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; CYTOKINESIS; FEMALE; FLOW CYTOMETRY; IMMUNOPATHOGENESIS; IMMUNOREGULATION; MALE; MOUSE; NONHUMAN; PNEUMONIA; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ALVEOLITIS, EXTRINSIC ALLERGIC; ANIMALS; CELL SEPARATION; CYTOKINES; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; FLOW CYTOMETRY; GENE EXPRESSION; GENE EXPRESSION REGULATION; INTERLEUKIN-17; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SACCHAROPOLYSPORA; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 6;

EID: 77950504533     PISSN: 00192805     EISSN: 13652567     Source Type: Journal    
DOI: 10.1111/j.1365-2567.2009.03219.x     Document Type: Article

References (50)

1. Barrios RJ. Hypersensitivity pneumonitis: histopathology. Arch Pathol Lab Med 2008 132 : 199 203.
2. Takemura T, Akashi T, Ohtani Y, Inase N, Yoshizawa Y. Pathology of hypersensitivity pneumonitis. Curr Opin Pulm Med 2008 14 : 440 454.
3. Churg A, Muller NL, Flint J, Wright JL. Chronic hypersensitivity pneumonitis. Am J Surg Pathol 2006 30 : 201 208.
4. Madison JM. Hypersensitivity pneumonitis: clinical perspectives. Arch Pathol Lab Med 2008 132 : 195 198.
5. Bourke SJ, Dalphin JC, Boyd G, McSharry C, Baldwin CI, Calvert JE. Hypersensitivity pneumonitis: current concepts. Eur Respir J Suppl 2001 32 : 81s 92s.
6. Story RE, Grammer LC. Hypersensitivity pneumonitis. Allergy Asthma Proc 2004 25 : S40 1.
7. Suda T, Chida K, Hayakawa H, Imokawa S, Iwata M, Nakamura H, Sato A. Development of bronchus-associated lymphoid tissue in chronic hypersensitivity pneumonitis. Chest 1999 115 : 357 363.
8. McClellan JS, Albers GM, Noyes BE, Sotelo C, Petterchak JA, Knutsen AP. B-lymphocyte aggregates in alveoli from a child with hypersensitivity pneumonitis (bird breeders lung). Ann Allergy Asthma Immunol 1999 83 : 357 360.
9. Takizawa H, Ohta K, Horiuchi T et al. Hypersensitivity pneumonitis in athymic nude mice. Additional evidence of T cell dependency. Am Rev Respir Dis 1992 146 : 479 484.
10. Woda BA. Hypersensitivity pneumonitis: an immunopathology review. Arch Pathol Lab Med 2008 132 : 204 205.
11. Butler NS, Monick MM, Yarovinsky TO, Powers LS, Hunninghake GW. Altered IL-4 mRNA stability correlates with Th1 and Th2 bias and susceptibility to hypersensitivity pneumonitis in two inbred strains of mice. J Immunol 2002 169 : 3700 3709.
12. Schuyler M, Gott K, Cherne A. Mediators of hypersensitivity pneumonitis. J Lab Clin Med 2000 136 : 29 38.
13. Gudmundsson G, Hunninghake GW. Interferon-γ is necessary for the expression of hypersensitivity pneumonitis. J Clin Invest 1997 99 : 2386 2390. (Pubitemid 27227715)
14. Nance S, Cross R, Yi AK, Fitzpatrick EA. IFN-γ production by innate immune cells is sufficient for development of hypersensitivity pneumonitis. Eur J Immunol 2005 35 : 1928 1938.
15. Matsuno Y, Ishii Y, Yoh K et al. Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis. Am J Respir Crit Care Med 2007 176 : 1015 1025.
16. + cells adoptively transfer experimental hypersensitivity pneumonitis. Cell Immunol 1997 177 : 169 175.
17. Chiang EY, Kolumam GA, Yu X et al. Targeted depletion of lymphotoxin-alpha-expressing T(H)1 and T(H)17 cells inhibits autoimmune disease. Nat Med 2009 15 : 766 773.
18. Monari C, Bevilacqua S, Piccioni M et al. A microbial polysaccharide reduces the severity of rheumatoid arthritis by influencing th17 differentiation and proinflammatory cytokines production. J Immunol 2009 183 : 191 200.
19. Werner JL, Metz AE, Horn D et al. Requisite role for the dectin-1 β-glucan receptor in pulmonary defense against Aspergillus fumigatus. J Immunol 2009 182 : 4938 4946.
20. Joshi AD, Fong DJ, Oak SR, Trujillo G, Flaherty KR, Martinez FJ, Hogaboam CM. Interleukin-17-mediated immunopathogenesis in experimental hypersensitivity pneumonitis. Am J Respir Crit Care Med 2009 179 : 705 716.
21. Simonian PL, Roark CL, Wehrmann F, Lanham AK, Diaz del Valle F, Born WK, O'Brien RL, Fontenot AP. Th17-polarized immune response in a murine model of hypersensitivity pneumonitis and lung fibrosis. J Immunol 2009 182 : 657 665.
22. Fossiez F, Djossou O, Chomarat P et al. T cell interleukin-17 induces stromal cells to produce proinflammatory and hematopoietic cytokines. J Exp Med 1996 183 : 2593 2603.
23. Laan M, Cui ZH, Hoshino H, Lotvall J, Sjostrand M, Gruenert DC, Skoogh BE, Linden A. Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J Immunol 1999 162 : 2347 2352.
24. Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK. Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells. Nature 2006 441 : 235 238.
25. Kimura A, Naka T, Kishimoto T. IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells. Proc Natl Acad Sci U S A 2007 104 : 12099 12104.
26. Langrish CL, Chen Y, Blumenschein WM et al. IL-23 drives a pathogenic T cell population that induces autoimmune inflammation. J Exp Med 2005 201 : 233 240.
27. Mangan PR, Harrington LE, O'Quinn DB et al. Transforming growth factor-β induces development of the T(H)17 lineage. Nature 2006 441 : 231 234.
28. Korn T, Bettelli E, Gao W, Awasthi A, Jager A, Strom TB, Oukka M, Kuchroo VK. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 2007 448 : 484 487.
29. Nurieva R, Yang XO, Martinez G et al. Essential autocrine regulation by IL-21 in the generation of inflammatory T cells. Nature 2007 448 : 480 483.
30. Werling D, Jungi TW. TOLL-like receptors linking innate and adaptive immune response. Vet Immunol Immunopathol 2003 91 : 1 12.
31. Takeuchi O, Kawai T, Muhlradt PF, Morr M, Radolf JD, Zychlinsky A, Takeda K, Akira S. Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 2001 13 : 933 940.
32. Takeuchi O, Kawai T, Sanjo H, Copeland NG, Gilbert DJ, Jenkins NA, Takeda K, Akira S. TLR6: a novel member of an expanding toll-like receptor family. Gene 1999 231 : 59 65.
33. Lakatos HF, Burgess HA, Thatcher TH, Redonnet MR, Hernady E, Williams JP, Sime PJ. Oropharyngeal aspiration of a silica suspension produces a superior model of silicosis in the mouse when compared to intratracheal instillation. Exp Lung Res 2006 32 : 181 199.
34. Hwang SJ, Kim S, Park WS, Chung DH. IL-4-secreting NKT cells prevent hypersensitivity pneumonitis by suppressing IFN-γ-producing neutrophils. J Immunol 2006 177 : 5258 5268.
35. Tassi I, Cella M, Castro I, Gilfillan S, Khan WN, Colonna M. Requirement of phospholipase C-γ2 (PLCγ2) for Dectin-1-induced antigen presentation and induction of TH1/TH17 polarization. Eur J Immunol 2009 39 : 1369 1378.
36. Thorne PS, Adamcakova-Dodd A, Kelly KM, O'Neill ME, Duchaine C. Metalworking fluid with mycobacteria and endotoxin induces hypersensitivity pneumonitis in mice. Am J Respir Crit Care Med 2006 173 : 759 768.
37. Aggarwal S, Ghilardi N, Xie MH, de Sauvage FJ, Gurney AL. Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17. J Biol Chem 2003 278 : 1910 1914.
38. Zhou L, Ivanov II, Spolski R et al. IL-6 programs T(H)-17 cell differentiation by promoting sequential engagement of the IL-21 and IL-23 pathways. Nat Immunol 2007 8 : 967 974.
39. Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B. TGF-β in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 2006 24 : 179 189.
40. Gocke AR, Cravens PD, Ben LH, Hussain RZ, Northrop SC, Racke MK, Lovett-Racke AE. T-bet regulates the fate of Th1 and Th17 lymphocytes in autoimmunity. J Immunol 2007 178 : 1341 1348.
41. Oshima M, Maeda A, Ishioka S, Hiyama K, Yamakido M. Expression of C-C chemokines in bronchoalveolar lavage cells from patients with granulomatous lung diseases. Lung 1999 177 : 229 240.
42. Nance SC, Yi AK, Re FC, Fitzpatrick EA. MyD88 is necessary for neutrophil recruitment in hypersensitivity pneumonitis. J Leukoc Biol 2008 83 : 1207 1217.
43. LeibundGut-Landmann S, Gross O, Robinson MJ et al. Syk- and CARD9-dependent coupling of innate immunity to the induction of T helper cells that produce interleukin 17. Nat Immunol 2007 8 : 630 638.
44. O'Connor W Jr., Kamanaka M, Booth CJ, Town T, Nakae S, Iwakura Y, Kolls JK, Flavell RA. A protective function for interleukin 17A in T cell-mediated intestinal inflammation. Nat Immunol 2009 10 : 603 609.
45. Rangachari M, Mauermann N, Marty RR, Dirnhofer S, Kurrer MO, Komnenovic V, Penninger JM, Eriksson U. T-bet negatively regulates autoimmune myocarditis by suppressing local production of interleukin 17. J Exp Med 2006 203 : 2009 2019.
46. Cerhan JR, Ansell SM, Fredericksen ZS et al. Genetic variation in 1253 immune and inflammation genes and risk of non-Hodgkin lymphoma. Blood 2007 110 : 4455 4463.
47. Kormann MS, Depner M, Hartl D et al. Toll-like receptor heterodimer variants protect from childhood asthma. J Allergy Clin Immunol 2008 122 : 86 92. 92 e81-88.
48. Purdue MP, Lan Q, Wang SS et al. A pooled investigation of Toll-like receptor gene variants and risk of non-Hodgkin lymphoma. Carcinogenesis 2009 30 : 275 281.
49. Sun J, Wiklund F, Zheng SL et al. Sequence variants in Toll-like receptor gene cluster (TLR6-TLR1-TLR10) and prostate cancer risk. J Natl Cancer Inst 2005 97 : 525 532.
50. Simonian PL, Roark CL, Wehrmann F, Lanham AM, Born WK, O'Brien RL, Fontenot AP. IL-17A-expressing T cells are essential for bacterial clearance in a murine model of hypersensitivity pneumonitis. J Immunol 2009 182 : 6540 6549.