메뉴 건너뛰기




Volumn 19, Issue 5, 2011, Pages 388-396

Nanoparticle-based delivery for the treatment of inner ear disorders

Author keywords

gene therapy; internalization; nanogels; nanoparticles; Piggy Bac; targetability; transfection

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; CAVEOLIN; CHITOSAN; CLATHRIN; GREEN FLUORESCENT PROTEIN; GROWTH FACTOR; HYPERBRANCHED POLYLYSINE; LIPOSOME; MATH 1; NANOCARRIER; NANOGEL; NANOPARTICLE; NERVE GROWTH FACTOR DERIVED PEPTIDE; PEPTIDE; POLYETHYLENEIMINE; POLYGLYCOLIC ACID; POLYLACTIC ACID; POLYMER; PRESTIN; PROTEIN; PROTEIN P57; SHORT HAIRPIN RNA; SOLID LIPID NANOPARTICLE; STEROID; SUPERPARAMAGNETIC IRON OXIDE; TET1 PEPTIDE; TRANS ACTING ACTIVATOR OF TRANSCRIPTION PEPTIDE; TRISIALOGANGLIOSIDE CLOSTRIDIAL TOXIN; TROPOMYOCIN RECEPTOR KINASE B; UNCLASSIFIED DRUG; UNINDEXED DRUG;

EID: 80052729461     PISSN: 10689508     EISSN: 15316998     Source Type: Journal    
DOI: 10.1097/MOO.0b013e32834aa3a8     Document Type: Review
Times cited : (28)

References (92)
  • 1
    • 59249092022 scopus 로고    scopus 로고
    • Muscular gene transfer using nonviral vectors
    • Braun S. Muscular gene transfer using nonviral vectors. Curr Gene Ther 2008; 8:391-405.
    • (2008) Curr Gene Ther , vol.8 , pp. 391-405
    • Braun, S.1
  • 2
    • 72649096482 scopus 로고    scopus 로고
    • Sample purification improves the analysis of nonviral in vivo gene transfection
    • Soininen P, Hanzlikova M, Paukkunen M, et al. Sample purification improves the analysis of nonviral in vivo gene transfection. Plasmid 2010; 63:27-30.
    • (2010) Plasmid , vol.63 , pp. 27-30
    • Soininen, P.1    Hanzlikova, M.2    Paukkunen, M.3
  • 3
    • 22244459917 scopus 로고    scopus 로고
    • Gene therapy: Twenty-first century medicine
    • DOI 10.1146/annurev.biochem.74.050304.091637
    • Verma IM, Weitzman MD. Gene therapy: twenty-first century medicine. Annu Rev Biochem 2005; 74:711-738. (Pubitemid 40995522)
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 711-738
    • Verma, I.M.1    Weitzman, M.D.2
  • 5
    • 0038745599 scopus 로고    scopus 로고
    • Progress and problems with the use of viral vectors for gene therapy
    • DOI 10.1038/nrg1066
    • Thomas CE, Ehrhardt A, Kay MA. Progress and problems with the use of viral vectors for gene therapy. Nat Rev Genet 2003; 4:346-358. (Pubitemid 36538359)
    • (2003) Nature Reviews Genetics , vol.4 , Issue.5 , pp. 346-358
    • Thomas, C.E.1    Ehrhardt, A.2    Kay, M.A.3
  • 6
    • 0032580348 scopus 로고    scopus 로고
    • Human gene therapy
    • Anderson WF. Human gene therapy. Nature 1998; 392:25-30. (Pubitemid 28215190)
    • (1998) Nature , vol.392 , Issue.6679 SUPPL. , pp. 25-30
    • Anderson, W.F.1
  • 7
    • 0035941087 scopus 로고    scopus 로고
    • Gene therapy: Safer and virus-free?
    • DOI 10.1126/science.294.5547.1638
    • Ferber D. Gene therapy: safer and virus-free? Science 2001; 294:1638-1642. (Pubitemid 33104814)
    • (2001) Science , vol.294 , Issue.5547 , pp. 1638-1642
    • Ferber, D.1
  • 8
    • 0036954247 scopus 로고    scopus 로고
    • Gene therapy progress and prospects: Nonviral vectors
    • DOI 10.1038/sj.gt.3301923
    • Niidome T, Huang L. Gene therapy progress and prospects: nonviral vectors. Gene Ther 2002; 9:1647-1652. (Pubitemid 36104607)
    • (2002) Gene Therapy , vol.9 , Issue.24 , pp. 1647-1652
    • Niidome, T.1    Huang, L.2
  • 9
    • 0037294039 scopus 로고    scopus 로고
    • Non-viral and hybrid vectors in human gene therapy: An update
    • DOI 10.1016/S1471-4914(03)00005-4
    • Schmidt-Wolf GD, Schmidt-Wolf IG. Nonviral and hybrid vectors in human gene therapy: an update. Trends Mol Med 2003; 9:67-72. (Pubitemid 36313867)
    • (2003) Trends in Molecular Medicine , vol.9 , Issue.2 , pp. 67-72
    • Schmidt-Wolf, G.D.1    Schmidt-Wolf, I.G.H.2
  • 10
    • 34248570405 scopus 로고    scopus 로고
    • Efficient nonviral ocular gene transfer with compacted DNA nanoparticles
    • Farjo R, Skaggs J, Quiambao AB, et al. Efficient nonviral ocular gene transfer with compacted DNA nanoparticles. PLoS One 2006; 1:e38.
    • (2006) PLoS One , vol.1
    • Farjo, R.1    Skaggs, J.2    Quiambao, A.B.3
  • 12
    • 33749983751 scopus 로고    scopus 로고
    • Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer
    • DOI 10.1038/nmat1737, PII NMAT1737
    • Wang Y, Gao S, Ye WH, et al. Co-delivery of drugs and DNA from cationic core-shell nanoparticles self-assembled from a biodegradable copolymer. Nat Mater 2006; 5:791-796. (Pubitemid 44570860)
    • (2006) Nature Materials , vol.5 , Issue.10 , pp. 791-796
    • Wang, Y.1    Gao, S.2    Ye, W.-H.3    Yoon, H.S.4    Yang, Y.-Y.5
  • 13
    • 57149131570 scopus 로고    scopus 로고
    • Nanoparticles as protein and gene carriers to mucosal surfaces
    • de la Fuente M, Csaba N, Garcia-Fuentes M, et al. Nanoparticles as protein and gene carriers to mucosal surfaces. Nanomedicine (Lond) 2008; 3:845-857.
    • (2008) Nanomedicine (Lond) , vol.3 , pp. 845-857
    • De La Fuente, M.1    Csaba, N.2    Garcia-Fuentes, M.3
  • 15
    • 0035858332 scopus 로고    scopus 로고
    • Recent progress in gene delivery using non-viral transfer complexes
    • DOI 10.1016/S0168-3659(01)00267-X, PII S016836590100267X
    • Godbey WT, Mikos AG. Recent progress in gene delivery using nonviral transfer complexes. J Control Release 2001; 72:115-125. (Pubitemid 32522349)
    • (2001) Journal of Controlled Release , vol.72 , Issue.1-3 , pp. 115-125
    • Godbey, W.T.1    Mikos, A.G.2
  • 16
    • 41349117915 scopus 로고    scopus 로고
    • Distribution of lipid nanocapsules in different cochlear cell populations after round window membrane permeation
    • Zou J, Saulnier P, Perrier T, et al. Distribution of lipid nanocapsules in different cochlear cell populations after round window membrane permeation. J Biomed Mater Res B Appl Biomater 2008; 87:10-18.
    • (2008) J Biomed Mater Res B Appl Biomater , vol.87 , pp. 10-18
    • Zou, J.1    Saulnier, P.2    Perrier, T.3
  • 17
    • 79952644327 scopus 로고    scopus 로고
    • Visualization of intracellular trafficking of Math1 protein in different cell types with a newly-constructed nonviral gene delivery plasmid
    • Zhang W, Zhang Y, Sood R, et al. Visualization of intracellular trafficking of Math1 protein in different cell types with a newly-constructed nonviral gene delivery plasmid. J Gene Med 2011; 13:134-144.
    • (2011) J Gene Med , vol.13 , pp. 134-144
    • Zhang, W.1    Zhang, Y.2    Sood, R.3
  • 18
    • 70349133557 scopus 로고    scopus 로고
    • Potential novel drug carriers for inner ear treatment: Hyperbranched polylysine and lipid nanocapsules
    • Scheper V, Wolf M, Scholl M, et al. Potential novel drug carriers for inner ear treatment: hyperbranched polylysine and lipid nanocapsules. Nanomedicine (Lond) 2009; 4:623-635.
    • (2009) Nanomedicine (Lond) , vol.4 , pp. 623-635
    • Scheper, V.1    Wolf, M.2    Scholl, M.3
  • 19
    • 77957556177 scopus 로고    scopus 로고
    • Inner ear drug delivery system from the clinical point of view
    • Sakamoto T, Nakagawa T, Horie RT, et al. Inner ear drug delivery system from the clinical point of view. Acta Otolaryngol Suppl 2010; 130:101-104.
    • (2010) Acta Otolaryngol Suppl , vol.130 , pp. 101-104
    • Sakamoto, T.1    Nakagawa, T.2    Horie, R.T.3
  • 20
    • 77951497907 scopus 로고    scopus 로고
    • Cell-specific targeting in the mouse inner ear using nanoparticles conjugated with a neurotrophin-derived peptide ligand: Potential tool for drug delivery
    • Roy S, Johnston AH, Newman TA, et al. Cell-specific targeting in the mouse inner ear using nanoparticles conjugated with a neurotrophin-derived peptide ligand: potential tool for drug delivery. Int J Pharm 2010; 390:214-224.
    • (2010) Int J Pharm , vol.390 , pp. 214-224
    • Roy, S.1    Johnston, A.H.2    Newman, T.A.3
  • 21
    • 80052699149 scopus 로고    scopus 로고
    • Current status and prospects of gene therapy for the inner ear
    • Sun H, Huang A, Cao S. Current status and prospects of gene therapy for the inner ear. Hum Gene Ther 2011; 22:1-12.
    • (2011) Hum Gene Ther , vol.22 , pp. 1-12
    • Sun, H.1    Huang, A.2    Cao, S.3
  • 22
    • 79851495498 scopus 로고    scopus 로고
    • Disposition of nanoparticle-based delivery system via inner ear administration
    • Chen G, Zhang X, Yang F, et al. Disposition of nanoparticle-based delivery system via inner ear administration. Curr Drug Metab 2010; 11:886-897.
    • (2010) Curr Drug Metab , vol.11 , pp. 886-897
    • Chen, G.1    Zhang, X.2    Yang, F.3
  • 23
    • 33750969047 scopus 로고    scopus 로고
    • Cell-Gene Delivery of Brain-Derived Neurotrophic Factor to the Mouse Inner Ear
    • DOI 10.1016/j.ymthe.2006.06.012, PII S1525001606002644
    • Okano T, Nakagawa T, Kita T, et al. Cell-gene delivery of brain-derived neurotrophic factor to the mouse inner ear. Mol Ther 2006; 14:866-871. (Pubitemid 44743126)
    • (2006) Molecular Therapy , vol.14 , Issue.6 , pp. 866-871
    • Okano, T.1    Nakagawa, T.2    Kita, T.3    Endo, T.4    Ito, J.5
  • 24
    • 64549134676 scopus 로고    scopus 로고
    • Nonviral vectors for gene delivery
    • Mintzer MA, Simanek EE. Nonviral vectors for gene delivery. Chem Rev 2009; 109:259-302.
    • (2009) Chem Rev , vol.109 , pp. 259-302
    • Mintzer, M.A.1    Simanek, E.E.2
  • 25
    • 84873092948 scopus 로고    scopus 로고
    • Reflection paper on nanotechnology-based medicinal products for human use
    • Committee for Medicinal Products for Human Use (CHMP)
    • Committee for Medicinal Products for Human Use (CHMP). Reflection paper on nanotechnology-based medicinal products for human use. In EMEA/ CHMP/79769/2006; 2006. www.ema.europa.eu/docs/en-GB/document-library/Report/ 2010/01/WC500069730.pdf
    • (2006) EMEA/CHMP/79769/2006
  • 26
    • 78650937847 scopus 로고    scopus 로고
    • Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium
    • Zou J, Sood R, Ranjan S, et al. Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium. J Nanobiotechnol 2011; 8:32.
    • (2011) J Nanobiotechnol , vol.8 , pp. 32
    • Zou, J.1    Sood, R.2    Ranjan, S.3
  • 27
    • 77951498533 scopus 로고    scopus 로고
    • Vitro drug release mechanism from lipid nanocapsules (LNC)
    • Abdel-Mottaleb MM, Neumann D, Lamprecht A. In vitro drug release mechanism from lipid nanocapsules (LNC). Int J Pharm 2010; 390:208-213.
    • (2010) Int J Pharm , vol.390 , pp. 208-213
    • Abdel-Mottaleb, M.M.1    Neumann, D.2    Lamprecht, A.3
  • 28
    • 49949094165 scopus 로고    scopus 로고
    • Polyethylenimine-mediated cochlear gene transfer in guinea pigs
    • Tan BT, Foong KH, Lee MM, et al. Polyethylenimine-mediated cochlear gene transfer in guinea pigs. Arch Otolaryngol Head Neck Surg 2008; 134:884-891.
    • (2008) Arch Otolaryngol Head Neck Surg , vol.134 , pp. 884-891
    • Tan, B.T.1    Foong, K.H.2    Lee, M.M.3
  • 29
    • 76249084076 scopus 로고    scopus 로고
    • Sustained delivery of lidocaine into the cochlea using poly lactic/glycolic acid microparticles
    • Horie RT, Sakamoto T, Nakagawa T, et al. Sustained delivery of lidocaine into the cochlea using poly lactic/glycolic acid microparticles. Laryngoscope 2010; 120:377-383.
    • (2010) Laryngoscope , vol.120 , pp. 377-383
    • Horie, R.T.1    Sakamoto, T.2    Nakagawa, T.3
  • 30
    • 79955417361 scopus 로고    scopus 로고
    • From lactic acid to poly(lactic acid) (PLA): Characterization and analysis of PLA and its precursors
    • Inkinen S, Hakkarainen M, Albertsson AC, et al. From lactic acid to poly(lactic acid) (PLA): characterization and analysis of PLA and its precursors. Biomacromolecules 2011; 12:523-532.
    • (2011) Biomacromolecules , vol.12 , pp. 523-532
    • Inkinen, S.1    Hakkarainen, M.2    Albertsson, A.C.3
  • 31
    • 81155146636 scopus 로고    scopus 로고
    • Enhanced antiproliferative activity of Herceptin (HER2)-conjugated gemcitabine-loaded chitosan nanoparticle in pancreatic cancer therapy
    • in press
    • Arya G, Vandana M, Acharya S et al. Enhanced antiproliferative activity of Herceptin (HER2)-conjugated gemcitabine-loaded chitosan nanoparticle in pancreatic cancer therapy. Nanomedicine 2011 (in press).
    • (2011) Nanomedicine
    • Arya, G.1    Vandana, M.2    Acharya, S.3
  • 32
    • 80052760630 scopus 로고    scopus 로고
    • Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells
    • Zhang W, Zhang Y, Lobler M, et al. Nuclear entry of hyperbranched polylysine nanoparticles into cochlear cells. Int J Nanomedicine 2011; 6:535-546.
    • (2011) Int J Nanomedicine , vol.6 , pp. 535-546
    • Zhang, W.1    Zhang, Y.2    Lobler, M.3
  • 34
    • 77956344273 scopus 로고    scopus 로고
    • Improving the visualization of fluorescently tagged nanoparticles and fluorophore-labeled molecular probes by treatment with CuSO(4) to quench autofluorescence in the rat inner ear
    • Zhang Y, Zhang W, Johnston AH, et al. Improving the visualization of fluorescently tagged nanoparticles and fluorophore-labeled molecular probes by treatment with CuSO(4) to quench autofluorescence in the rat inner ear. Hear Res 2010; 269:1-11.
    • (2010) Hear Res , vol.269 , pp. 1-11
    • Zhang, Y.1    Zhang, W.2    Johnston, A.H.3
  • 35
    • 79961061029 scopus 로고    scopus 로고
    • Impact of silica nanoparticle design on cellular toxicity and hemolytic activity
    • in press
    • Yu T, Malugin A, Ghandehari H. Impact of silica nanoparticle design on cellular toxicity and hemolytic activity. ACS Nano 2011 (in press).
    • (2011) ACS Nano
    • Yu, T.1    Malugin, A.2    Ghandehari, H.3
  • 37
    • 80052277039 scopus 로고    scopus 로고
    • Proinflammatory effects of bare and PEGylated ORMOSIL- PLGA- and SUV-NPs on monocytes and PMNs and their modulation by f-MLP
    • in press
    • Segat D, Tavano R, Donini M et al. Proinflammatory effects of bare and PEGylated ORMOSIL-, PLGA- and SUV-NPs on monocytes and PMNs and their modulation by f-MLP. Nanomedicine (Lond) 2011 (in press).
    • (2011) Nanomedicine (Lond)
    • Segat, D.1    Tavano, R.2    Donini, M.3
  • 38
    • 33750595541 scopus 로고    scopus 로고
    • Pegylated nanocapsules produced by an organic solvent-free method: Evaluation of their stealth properties
    • Beduneau A, Saulnier P, Anton N, et al. Pegylated nanocapsules produced by an organic solvent-free method: Evaluation of their stealth properties. Pharm Res 2006; 23:2190-2199.
    • (2006) Pharm Res , vol.23 , pp. 2190-2199
    • Beduneau, A.1    Saulnier, P.2    Anton, N.3
  • 39
    • 79955101308 scopus 로고    scopus 로고
    • Ternary complexes of amphiphilic polycaprolactone- graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft- poly(ethylene glycol) for gene delivery
    • Guo S, Huang Y, Zhang W, et al. Ternary complexes of amphiphilic polycaprolactone- graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery. Biomaterials 2011; 32:4283-4292.
    • (2011) Biomaterials , vol.32 , pp. 4283-4292
    • Guo, S.1    Huang, Y.2    Zhang, W.3
  • 40
    • 34548494402 scopus 로고    scopus 로고
    • Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab' fragments
    • DOI 10.1016/j.biomaterials.2007.05.014, PII S0142961207004176
    • Beduneau A, Saulnier P, Hindre F, et al. Design of targeted lipid nanocapsules by conjugation of whole antibodies and antibody Fab' fragments. Biomaterials 2007; 28:4978-4990. (Pubitemid 47371148)
    • (2007) Biomaterials , vol.28 , Issue.33 , pp. 4978-4990
    • Beduneau, A.1    Saulnier, P.2    Hindre, F.3    Clavreul, A.4    Leroux, J.-C.5    Benoit, J.-P.6
  • 41
    • 79951578276 scopus 로고    scopus 로고
    • Enhanced endosomal escape of siRNAincorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity
    • Pittella F, Zhang M, Lee Y, et al. Enhanced endosomal escape of siRNAincorporating hybrid nanoparticles from calcium phosphate and PEG-block charge-conversional polymer for efficient gene knockdown with negligible cytotoxicity. Biomaterials 2011; 32:3106-3114.
    • (2011) Biomaterials , vol.32 , pp. 3106-3114
    • Pittella, F.1    Zhang, M.2    Lee, Y.3
  • 42
    • 79952641897 scopus 로고    scopus 로고
    • Endosome-disruptive peptides for improving cytosolic delivery of bioactive macromolecules
    • Nakase I, Kobayashi S, Futaki S. Endosome-disruptive peptides for improving cytosolic delivery of bioactive macromolecules. Biopolymers 2010; 94:763-770.
    • (2010) Biopolymers , vol.94 , pp. 763-770
    • Nakase, I.1    Kobayashi, S.2    Futaki, S.3
  • 43
    • 70349920791 scopus 로고    scopus 로고
    • Nanogels as pharmaceutical carriers: Finite networks of infinite capabilities
    • Kabanov AV, Vinogradov SV. Nanogels as pharmaceutical carriers: finite networks of infinite capabilities. Angew Chem Int Ed Engl 2009; 48:5418-5429.
    • (2009) Angew Chem Int Ed Engl , vol.48 , pp. 5418-5429
    • Kabanov, A.V.1    Vinogradov, S.V.2
  • 44
    • 79251483489 scopus 로고    scopus 로고
    • Thermoreversible Pluronic F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: In vitro drug release, cell cytotoxicity, and uptake studies
    • Nie S, Hsiao WL, Pan W, et al. Thermoreversible Pluronic F127-based hydrogel containing liposomes for the controlled delivery of paclitaxel: in vitro drug release, cell cytotoxicity, and uptake studies. Int J Nanomedicine 2011; 6:151-166.
    • (2011) Int J Nanomedicine , vol.6 , pp. 151-166
    • Nie, S.1    Hsiao, W.L.2    Pan, W.3
  • 45
    • 77955722626 scopus 로고    scopus 로고
    • Magnetic resonance imaging of the inner ear in Meniere's disease
    • Pyykko I, Zou J, Poe D, et al. Magnetic resonance imaging of the inner ear in Meniere's disease. Otolaryngol Clin North Am 2010; 43:1059-1080.
    • (2010) Otolaryngol Clin North Am , vol.43 , pp. 1059-1080
    • Pyykko, I.1    Zou, J.2    Poe, D.3
  • 46
    • 79956340120 scopus 로고    scopus 로고
    • Visualization and analysis of superparamagnetic iron oxide nanoparticles in the inner ear by light microscopy and energy filtered TEM
    • Thaler M, Roy S, Fornara A, et al. Visualization and analysis of superparamagnetic iron oxide nanoparticles in the inner ear by light microscopy and energy filtered TEM. Nanomedicine 2011; 7:360-369.
    • (2011) Nanomedicine , vol.7 , pp. 360-369
    • Thaler, M.1    Roy, S.2    Fornara, A.3
  • 47
    • 0036182103 scopus 로고    scopus 로고
    • Prevention of antibody-mediated elimination of ligand-targeted liposomes by using poly(ethylene glycol)-modified lipids
    • DOI 10.1124/jpet.300.3.976
    • Li WM, Mayer LD, Bally MB. Prevention of antibody-mediated elimination of ligand-targeted liposomes by using poly(ethylene glycol)-modified lipids. J Pharmacol Exp Ther 2002; 300:976-983. (Pubitemid 34165004)
    • (2002) Journal of Pharmacology and Experimental Therapeutics , vol.300 , Issue.3 , pp. 976-983
    • Li, W.M.1    Mayer, L.D.2    Bally, M.B.3
  • 48
    • 78650937847 scopus 로고    scopus 로고
    • Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium
    • Zou J, Sood R, Ranjan S, et al. Manufacturing and in vivo inner ear visualization of MRI traceable liposome nanoparticles encapsulating gadolinium. J Nanobiotechnology 2010; 8:32.
    • (2010) J Nanobiotechnology , vol.8 , pp. 32
    • Zou, J.1    Sood, R.2    Ranjan, S.3
  • 49
    • 0343191443 scopus 로고    scopus 로고
    • 'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): Influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption
    • DOI 10.1016/S0927-7765(99)00156-3, PII S0927776599001563
    • Gref R, Luck M, Quellec P, et al. 'Stealth' corona-core nanoparticles surface modified by polyethylene glycol (PEG): influences of the corona (PEG chain length and surface density) and of the core composition on phagocytic uptake and plasma protein adsorption. Colloids Surf B Biointerfaces 2000; 18:301-313. (Pubitemid 30479870)
    • (2000) Colloids and Surfaces B: Biointerfaces , vol.18 , Issue.3-4 , pp. 301-313
    • Gref, R.1    Luck, M.2    Quellec, P.3    Marchand, M.4    Dellacherie, E.5    Harnisch, S.6    Blunk, T.7    Muller, R.H.8
  • 51
    • 0034989252 scopus 로고    scopus 로고
    • Quantification of solute entry into cochlear perilymph through the round window membrane
    • DOI 10.1016/S0378-5955(01)00223-4, PII S0378595501002234
    • Salt AN, Ma Y. Quantification of solute entry into cochlear perilymph through the round window membrane. Hear Res 2001; 154:88-97. (Pubitemid 32567538)
    • (2001) Hearing Research , vol.154 , Issue.1-2 , pp. 88-97
    • Salt, A.N.1    Ma, Y.2
  • 52
    • 44649157074 scopus 로고    scopus 로고
    • Immunodefense of the round window
    • DOI 10.1097/MLG.0b013e31816b30b0, PII 0000553720080600000019
    • Engmer C, Laurell G, Bagger-Sjoback D, et al. Immunodefense of the round window. Laryngoscope 2008; 118:1057-1062. (Pubitemid 351787278)
    • (2008) Laryngoscope , vol.118 , Issue.6 , pp. 1057-1062
    • Engmer, C.1    Laurell, G.2    Bagger-Sjoback, D.3    Rask-Andersen, H.4
  • 53
    • 0030941426 scopus 로고    scopus 로고
    • Round window membrane. Structure function and permeability: A review
    • DOI 10.1002/(SICI)1097-0029(19970201)36: 3<201::AID-JEMT8>3.0.CO;2- R
    • Goycoolea MV, Lundman L. Round window membrane. Structure function and permeability: a review. Microsc Res Tech 1997; 36:201-211. (Pubitemid 27120351)
    • (1997) Microscopy Research and Technique , vol.36 , Issue.3 , pp. 201-211
    • Goycoolea, M.V.1    Lundman, L.2
  • 54
    • 80052782409 scopus 로고    scopus 로고
    • Treatment of sudden sensorineural hearing loss with transtympanic injection of steroids as single therapy, a randomized clinical study
    • in press
    • Dispenza F, Amodio E, De Stefano A, et al. Treatment of sudden sensorineural hearing loss with transtympanic injection of steroids as single therapy, a randomized clinical study. Eur Arch Otorhinolaryngol 2011 (in press).
    • (2011) Eur Arch Otorhinolaryngol
    • Dispenza, F.1    Amodio, E.2    De Stefano, A.3
  • 55
    • 64549084550 scopus 로고    scopus 로고
    • Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: Implications for local drug delivery in humans
    • Mikulec AA, Plontke SK, Hartsock JJ, et al. Entry of substances into perilymph through the bone of the otic capsule after intratympanic applications in guinea pigs: implications for local drug delivery in humans. Otol Neurotol 2009; 30:131-138.
    • (2009) Otol Neurotol , vol.30 , pp. 131-138
    • Mikulec, A.A.1    Plontke, S.K.2    Hartsock, J.J.3
  • 56
    • 68849089967 scopus 로고    scopus 로고
    • The long-term effects of modified electrode surfaces and intracochlear corticosteroids on postoperative impedances in cochlear implant patients
    • Paasche G, Tasche C, Stover T, et al. The long-term effects of modified electrode surfaces and intracochlear corticosteroids on postoperative impedances in cochlear implant patients. Otol Neurotol 2009; 30:592-598.
    • (2009) Otol Neurotol , vol.30 , pp. 592-598
    • Paasche, G.1    Tasche, C.2    Stover, T.3
  • 57
    • 68549087158 scopus 로고    scopus 로고
    • Enhanced survival of spiral ganglion cells after cessation of treatment with brain-derived neurotrophic factor in deafened guinea pigs
    • Agterberg MJ, Versnel H, van Dijk LM, et al. Enhanced survival of spiral ganglion cells after cessation of treatment with brain-derived neurotrophic factor in deafened guinea pigs. J Assoc Res Otolaryngol 2009; 10:355-367.
    • (2009) J Assoc Res Otolaryngol , vol.10 , pp. 355-367
    • Agterberg, M.J.1    Versnel, H.2    Van Dijk, L.M.3
  • 59
    • 65449187581 scopus 로고    scopus 로고
    • The influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cells
    • Villanueva A, Canete M, Roca AG, et al. The influence of surface functionalization on the enhanced internalization of magnetic nanoparticles in cancer cells. Nanotechnology 2009; 20:115103.
    • (2009) Nanotechnology , vol.20 , pp. 115103
    • Villanueva, A.1    Canete, M.2    Roca, A.G.3
  • 60
    • 28844460780 scopus 로고    scopus 로고
    • Intracellular trafficking of nonviral vectors
    • DOI 10.1038/sj.gt.3302592, PII 3302592
    • Medina-Kauwe LK, Xie J, Hamm-Alvarez S. Intracellular trafficking of nonviral vectors. Gene Ther 2005; 12:1734-1751. (Pubitemid 41760286)
    • (2005) Gene Therapy , vol.12 , Issue.24 , pp. 1734-1751
    • Medina-Kauwe, L.K.1    Xie, J.2    Hamm-Alvarez, S.3
  • 61
    • 73949087550 scopus 로고    scopus 로고
    • Effect of surface properties on nanoparticle-cell interactions
    • Verma A, Stellacci F. Effect of surface properties on nanoparticle-cell interactions. Small 2010; 6:12-21.
    • (2010) Small , vol.6 , pp. 12-21
    • Verma, A.1    Stellacci, F.2
  • 63
    • 18044363648 scopus 로고    scopus 로고
    • Regeneration of human auditory nerve. In vitro/in video demonstration of neural progenitor cells in adult human and guinea pig spiral ganglion
    • DOI 10.1016/j.heares.2004.12.005
    • Rask-Andersen H, Bostrom M, Gerdin B, et al. Regeneration of human auditory nerve. In vitro/in video demonstration of neural progenitor cells in adult human and guinea pig spiral ganglion. Hear Res 2005; 203:180-191. (Pubitemid 40602827)
    • (2005) Hearing Research , vol.203 , Issue.1-2 , pp. 180-191
    • Rask-Andersen, H.1    Bostrom, M.2    Gerdin, B.3    Kinnefors, A.4    Nyberg, G.5    Engstrand, T.6    Miller, J.M.7    Lindholm, D.8
  • 64
    • 84934441973 scopus 로고    scopus 로고
    • Isolation of sphere-forming stem cells from the mouse inner ear
    • Oshima K, Senn P, Heller S. Isolation of sphere-forming stem cells from the mouse inner ear. Methods Mol Biol 2009; 493:141-162.
    • (2009) Methods Mol Biol , vol.493 , pp. 141-162
    • Oshima, K.1    Senn, P.2    Heller, S.3
  • 65
    • 38949169819 scopus 로고    scopus 로고
    • Stem-cell-based approaches for treating inner ear diseases [in German]
    • Senn P, Heller S. Stem-cell-based approaches for treating inner ear diseases [in German]. HNO 2008; 56:21-26.
    • (2008) HNO , vol.56 , pp. 21-26
    • Senn, P.1    Heller, S.2
  • 66
    • 79959952610 scopus 로고    scopus 로고
    • Neurotrophic receptors as potential therapy targets in postnatal development, in adult, and in hearing loss-affected inner ear
    • Bitsche M, Dudas J, Roy S, et al. Neurotrophic receptors as potential therapy targets in postnatal development, in adult, and in hearing loss-affected inner ear. Otol Neurotol 2011; 32:761-773.
    • (2011) Otol Neurotol , vol.32 , pp. 761-773
    • Bitsche, M.1    Dudas, J.2    Roy, S.3
  • 68
    • 74449086252 scopus 로고    scopus 로고
    • Targeted nonviral delivery vehicles to neural progenitor cells in the mouse subventricular zone
    • Kwon EJ, Lasiene J, Jacobson BE, et al. Targeted nonviral delivery vehicles to neural progenitor cells in the mouse subventricular zone. Biomaterials 2010; 31:2417-2424.
    • (2010) Biomaterials , vol.31 , pp. 2417-2424
    • Kwon, E.J.1    Lasiene, J.2    Jacobson, B.E.3
  • 69
    • 34548083701 scopus 로고    scopus 로고
    • Neuron-specific delivery of nucleic acids mediated by Tet1-modified poly(ethylenimine)
    • DOI 10.1002/jgm.1062
    • Park IK, Lasiene J, Chou SH, et al. Neuron-specific delivery of nucleic acids mediated by Tet1-modified poly(ethylenimine). J Gene Med 2007; 9:691-702. (Pubitemid 47288827)
    • (2007) Journal of Gene Medicine , vol.9 , Issue.8 , pp. 691-702
    • Park, I.-K.1    Lasiene, J.2    Chou, S.-H.3    Horner, P.J.4    Pun, S.H.5
  • 70
    • 58649116882 scopus 로고    scopus 로고
    • Immune atomic force microscopy of prestin-transfected CHO cells using quantum dots
    • Murakoshi M, Iida K, Kumano S, et al. Immune atomic force microscopy of prestin-transfected CHO cells using quantum dots. Pflugers Arch 2009; 457:885-898.
    • (2009) Pflugers Arch , vol.457 , pp. 885-898
    • Murakoshi, M.1    Iida, K.2    Kumano, S.3
  • 71
    • 20744435177 scopus 로고    scopus 로고
    • Nuclear entry of nonviral vectors
    • DOI 10.1038/sj.gt.3302534, Vector Traffic
    • Dean DA, Strong DD, Zimmer WE. Nuclear entry of nonviral vectors. Gene Ther 2005; 12:881-890. (Pubitemid 40852206)
    • (2005) Gene Therapy , vol.12 , Issue.11 , pp. 881-890
    • Dean, D.A.1    Strong, D.D.2    Zimmer, W.E.3
  • 72
    • 67349230653 scopus 로고    scopus 로고
    • Intracellular DNA release and elimination correlate poorly with transgene expression after nonviral transfection
    • Ruponen M, Arkko S, Urtti A, et al. Intracellular DNA release and elimination correlate poorly with transgene expression after nonviral transfection. J Control Release 2009; 136:226-231.
    • (2009) J Control Release , vol.136 , pp. 226-231
    • Ruponen, M.1    Arkko, S.2    Urtti, A.3
  • 73
    • 69949155656 scopus 로고    scopus 로고
    • A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo
    • Hatakeyama H, Ito E, Akita H, et al. A pH-sensitive fusogenic peptide facilitates endosomal escape and greatly enhances the gene silencing of siRNA-containing nanoparticles in vitro and in vivo. J Control Release 2009; 139:127-132.
    • (2009) J Control Release , vol.139 , pp. 127-132
    • Hatakeyama, H.1    Ito, E.2    Akita, H.3
  • 74
    • 1942438703 scopus 로고    scopus 로고
    • GALA: A designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery
    • DOI 10.1016/j.addr.2003.10.041, PII S0169409X03002801
    • Li W, Nicol F, Szoka FC Jr. GALA: a designed synthetic pH-responsive amphipathic peptide with applications in drug and gene delivery. Adv Drug Deliv Rev 2004; 56:967-985. (Pubitemid 38520204)
    • (2004) Advanced Drug Delivery Reviews , vol.56 , Issue.7 , pp. 967-985
    • Li, W.1    Nicol, F.2    Szoka Jr., F.C.3
  • 75
    • 0141921478 scopus 로고    scopus 로고
    • Acid-triggered release via dePEGylation of DOPE liposomes containing acid-labile vinyl ether PEG-lipids
    • DOI 10.1016/S0168-3659(03)00232-3
    • Shin J, Shum P, Thompson DH. Acid-triggered release via dePEGylation of DOPE liposomes containing acid-labile vinyl ether PEG-lipids. J Control Release 2003; 91:187-200. (Pubitemid 37288890)
    • (2003) Journal of Controlled Release , vol.91 , Issue.1-2 , pp. 187-200
    • Shin, J.1    Shum, P.2    Thompson, D.H.3
  • 76
    • 0036164351 scopus 로고    scopus 로고
    • Solute and macromolecule diffusion in cellular aqueous compartments
    • DOI 10.1016/S0968-0004(01)02003-5, PII S0968000401020035
    • Verkman AS. Solute and macromolecule diffusion in cellular aqueous compartments. Trends Biochem Sci 2002; 27:27-33. (Pubitemid 34131622)
    • (2002) Trends in Biochemical Sciences , vol.27 , Issue.1 , pp. 27-33
    • Verkman, A.S.1
  • 78
    • 0032805171 scopus 로고    scopus 로고
    • A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNA
    • Ludtke JJ, Zhang G, Sebestyen MG, et al. A nuclear localization signal can enhance both the nuclear transport and expression of 1 kb DNA. J Cell Sci 1999; 112 (Pt 12):2033-2041. (Pubitemid 29338827)
    • (1999) Journal of Cell Science , vol.112 , Issue.12 , pp. 2033-2041
    • Ludtke, J.J.1    Zhang, G.2    Sebestyen, M.G.3    Wolff, J.A.4
  • 79
    • 0036175701 scopus 로고    scopus 로고
    • Nuclear pore complex is able to transport macromolecules with diameters of ∼39 nm
    • DOI 10.1091/mbc.01-06-0308
    • Pante N, Kann M. Nuclear pore complex is able to transport macromolecules with diameters of about 39 nm. Mol Biol Cell 2002; 13:425-434. (Pubitemid 34165072)
    • (2002) Molecular Biology of the Cell , vol.13 , Issue.2 , pp. 425-434
    • Pante, N.1    Kann, M.2
  • 80
    • 20344401001 scopus 로고    scopus 로고
    • Application of novel solid lipid nanoparticle (SLN)-gene vector formulations based on a dimeric HIV-1 TAT-peptide in vitro and in vivo
    • DOI 10.1023/B:PHAM.0000041463.56768.ec
    • Rudolph C, Schillinger U, Ortiz A, et al. Application of novel solid lipid nanoparticle (SLN)-gene vector formulations based on a dimeric HIV-1 TAT-peptide in vitro and in vivo. Pharm Res 2004; 21:1662-1669. (Pubitemid 41184398)
    • (2004) Pharmaceutical Research , vol.21 , Issue.9 , pp. 1662-1669
    • Rudolph, C.1    Schillinger, U.2    Ortiz, A.3    Tabatt, K.4    Plank, C.5    Muller, R.H.6    Rosenecker, J.7
  • 82
    • 0042355293 scopus 로고    scopus 로고
    • Caveolae-mediated internalization of extracellular HIV-1 Tat fusion proteins visualized in real time
    • DOI 10.1016/S1525-0016(03)00122-9
    • Ferrari A, Pellegrini V, Arcangeli C, et al. Caveolae-mediated internalization of extracellular HIV-1 tat fusion proteins visualized in real time. Mol Ther 2003; 8:284-294. (Pubitemid 37062838)
    • (2003) Molecular Therapy , vol.8 , Issue.2 , pp. 284-294
    • Ferrari, A.1    Pellegrini, V.2    Arcangeli, C.3    Fittipaldi, A.4    Giacca, M.5    Beltram, F.6
  • 83
    • 2342595835 scopus 로고    scopus 로고
    • Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis
    • DOI 10.1038/nm996
    • Wadia JS, Stan RV, Dowdy SF. Transducible TAT-HA fusogenic peptide enhances escape of TAT-fusion proteins after lipid raft macropinocytosis. Nat Med 2004; 10:310-315. (Pubitemid 38667624)
    • (2004) Nature Medicine , vol.10 , Issue.3 , pp. 310-315
    • Wadia, J.S.1    Stan, R.V.2    Dowdy, S.F.3
  • 84
    • 17644386231 scopus 로고    scopus 로고
    • Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors
    • DOI 10.1074/jbc.M401604200
    • Richard JP, Melikov K, Brooks H, et al. Cellular uptake of unconjugated TAT peptide involves clathrin-dependent endocytosis and heparan sulfate receptors. J Biol Chem 2005; 280:15300-15306. (Pubitemid 40562886)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.15 , pp. 15300-15306
    • Richard, J.P.1    Melikov, K.2    Brooks, H.3    Prevot, P.4    Lebleu, B.5    Chernomordik, L.V.6
  • 86
    • 11144356131 scopus 로고    scopus 로고
    • The use of cell-penetrating peptides as a tool for gene regulation
    • DOI 10.1016/S1359-6446(04)03042-9, PII S1359644604030429
    • Jarver P, Langel U. The use of cell-penetrating peptides as a tool for gene regulation. Drug Discov Today 2004; 9:395-402. (Pubitemid 38479684)
    • (2004) Drug Discovery Today , vol.9 , Issue.9 , pp. 395-402
    • Jarver, P.1    Langel, U.2
  • 87
    • 0036792527 scopus 로고    scopus 로고
    • Peptide-mediated cell delivery: Application in protein target validation
    • Lindsay MA. Peptide-mediated cell delivery: application in protein target validation. Curr Opin Pharmacol 2002; 2:587-594.
    • (2002) Curr Opin Pharmacol , vol.2 , pp. 587-594
    • Lindsay, M.A.1
  • 90
    • 33846887854 scopus 로고    scopus 로고
    • Internalization of novel nonviral vector TAT-streptavidin into human cells
    • Rinne J, Albarran B, Jylhava J, et al. Internalization of novel nonviral vector TAT-streptavidin into human cells. BMC Biotechnol 2007; 7:1.
    • (2007) BMC Biotechnol , vol.7 , pp. 1
    • Rinne, J.1    Albarran, B.2    Jylhava, J.3
  • 91
    • 79959772184 scopus 로고    scopus 로고
    • Size matters: Versatile use of PiggyBac transposons as a genetic manipulation tool
    • Kim A, Pyykko I. Size matters: versatile use of PiggyBac transposons as a genetic manipulation tool. Mol Cell Biochem 2011; 354:301-309.
    • (2011) Mol Cell Biochem , vol.354 , pp. 301-309
    • Kim, A.1    Pyykko, I.2
  • 92
    • 79551699165 scopus 로고    scopus 로고
    • MRI of the cochlea with superparamagnetic iron oxide nanoparticles compared to gadolinium chelate contrast agents in a rat model
    • Poe P, Zou J, Zhang W, et al. MRI of the cochlea with superparamagnetic iron oxide nanoparticles compared to gadolinium chelate contrast agents in a rat model. Eur J Nanomed 2009; 2:29-36.
    • (2009) Eur J Nanomed , vol.2 , pp. 29-36
    • Poe, P.1    Zou, J.2    Zhang, W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.