Disposition of nanoparticle-based delivery system via inner ear administration

Current Drug Metabolism

Volumn 11, Issue 10, 2010, Pages 886-897

  Chen, Gang ^a   Zhang, Xiao ^a   Yang, Fan ^a   Mu, Lei ^a  

^a GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Cochlea; Intratympanic administration; Local drug delivery; Nanoparticles; Perilymph; Round window membrane

Indexed keywords

ANTIBIOTIC AGENT; ANTIOXIDANT; BETA GALACTOSIDASE; CONTRAST MEDIUM; DEXAMETHASONE; DEXAMETHASONE ACETATE; DEXAMETHASONE SODIUM PHOSPHATE; DRUG CARRIER; ENHANCED GREEN FLUORESCENT PROTEIN; FERRITIN; GREEN FLUORESCENT PROTEIN; HORSERADISH PEROXIDASE; HYDROXYAPATITE; INTERFERON; LIPID NANOPARTICLE; LIPOSOME; LOCAL ANESTHETIC AGENT; MAGNETIC NANOPARTICLE; NANOPARTICLE; NEUROTROPIC AGENT; POLYGLACTIN; POLYMERSOME; RHODAMINE; SILICON DIOXIDE; SOLID LIPID NANOPARTICLE; STEROID; SUPERPARAMAGNETIC IRON OXIDE NANOPARTICLE; TECHNETIUM 99M; TOXIN; UNCLASSIFIED DRUG; UNINDEXED DRUG;

ANATOMICAL VARIATION; AREA UNDER THE CURVE; ARTICLE; BIOCOMPATIBILITY; BIODEGRADATION; CEREBROSPINAL FLUID; COCHLEA; COCHLEA FENESTRA; CORTI ORGAN; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG COATING; DRUG DELIVERY SYSTEM; DRUG DISPOSITION; DRUG DISTRIBUTION; DRUG HALF LIFE; DRUG METABOLISM; EAR PROTECTION; EARDRUM; GUINEA PIG; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INNER EAR; LIPID BILAYER; LIPOSOMAL GENE DELIVERY SYSTEM; MEMBRANE PERMEABILITY; MIDDLE EAR; NANOENCAPSULATION; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; PARTICLE SIZE; PERILYMPH; SUSTAINED DRUG RELEASE; VIRAL GENE DELIVERY SYSTEM;

ANIMALS; BIOLOGICAL TRANSPORT; DRUG ADMINISTRATION ROUTES; DRUG CARRIERS; DRUG DELIVERY SYSTEMS; EAR, INNER; ENDOLYMPH; HUMANS; LABYRINTH DISEASES; LYMPHATIC SYSTEM; NANOMEDICINE; NANOPARTICLES; PERILYMPH; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; TISSUE DISTRIBUTION;

EID: 79851495498     PISSN: 13892002     EISSN: None     Source Type: Journal    
DOI: 10.2174/138920010794479673     Document Type: Article

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