Cell-specific targeting in the mouse inner ear using nanoparticles conjugated with a neurotrophin-derived peptide ligand: Potential tool for drug delivery

International Journal of Pharmaceutics

Volumn 390, Issue 2, 2010, Pages 214-224

  Roy, Soumen ^a   Johnston, Alex H ^c   Newman, Tracey A ^c   Glueckert, Rudolf ^a,b   Dudas, Jozsef ^a   Bitsche, Mario ^a   Corbacella, Elisa ^d   Rieger, Gunde ^a   Martini, Alessandro ^d   Schrott Fischer, Anneliese ^a  

^a INNSBRUCK MEDICAL UNIVERSITY   (Austria)

^b UNIVERSITY HOSPITAL INNSBRUCK   (Austria)

^c UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^d UNIVERSITY OF FERRARA   (Italy)

Author keywords

Hearing loss; Inner ear; Nanoparticles; Spiral ganglion neurons

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; LIGAND; NANOPARTICLE; NERVE GROWTH FACTOR; NEUROTROPHIN RECEPTOR P75; TYROSINE KINASE RECEPTOR;

AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CELL SPECIFICITY; CONCENTRATION (PARAMETERS); CONFOCAL LASER MICROSCOPY; CONTROLLED STUDY; DRUG CONJUGATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG PROTEIN BINDING; DRUG TARGETING; DRUG UPTAKE; EX VIVO STUDY; GENE EXPRESSION; HAIR CELL; HISTOLOGY; IMAGE DISPLAY; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; INNER EAR; LIGAND BINDING; MOUSE; NERVE FIBER; NONHUMAN; NUCLEOTIDE SEQUENCE; PHEOCHROMOCYTOMA CELL; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SCHWANN CELL; SPIRAL GANGLION; TARGET CELL;

ANIMALS; CELL CULTURE TECHNIQUES; CELL LINE, TUMOR; CELL SURVIVAL; DRUG DELIVERY SYSTEMS; DRUG SCREENING ASSAYS, ANTITUMOR; EAR, INNER; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, INBRED C57BL; NANOPARTICLES; NERVE GROWTH FACTOR; PEPTIDE FRAGMENTS;

EID: 77951497907     PISSN: 03785173     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2010.02.003     Document Type: Article

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