Synthetic triterpenoid cyano enone of methyl boswellate activates intrinsic, extrinsic, and endoplasmic reticulum stress cell death pathways in tumor cell lines

Molecular Cancer Therapeutics

Volumn 10, Issue 9, 2011, Pages 1635-1643

  Ravanan, Palaniyandi ^a,c   Sano, Renata ^a   Talwar, Priti ^a   Ogasawara, Satoshi ^a   Matsuzawa, Shu Ichi ^a   Cuddy, Michael ^a   Singh, Sanjay K ^b   Rao, G S R Subba ^b   Kondaiah, Paturu ^b   Reed, John C ^a  

^a BURNHAM INSTITUTE   (United States)

^b INDIAN INSTITUTE OF SCIENCE   (India)

^c VIT UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 6; ANTINEOPLASTIC AGENT; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; CASPASE 3; CASPASE 7; CASPASE 8; CASPASE 9; CYANO ENONE METHYL BOSWELLATE; PROTEIN BID; SMALL INTERFERING RNA; TRITERPENOID; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CELL STRAIN LNCAP; CELL VIABILITY; CONTROLLED STUDY; CYTOTOXICITY; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; GENE EXPRESSION; GLIOMA; IN VITRO STUDY; PRIORITY JOURNAL; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CASPASES; CELL DEATH; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVATION; HUMANS; NEOPLASMS; OLEANOLIC ACID; RECEPTORS, TNF-RELATED APOPTOSIS-INDUCING LIGAND; SIGNAL TRANSDUCTION; TRITERPENES;

EID: 80052715123     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-10-0887     Document Type: Article

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