The synthetic triterpenoid CDDO-Imidazolide suppresses STAT phosphorylation and induces apoptosis in myeloma and lung cancer cells.

Clinical cancer research : an official journal of the American Association for Cancer Research

Volumn 12, Issue 14 Pt 1, 2006, Pages 4288-4293

  Liby, Karen ^a   Voong, Nga ^a   Williams, Charlotte R ^a   Risingsong, Renee ^a   Royce, Darlene B ^a   Honda, Tadashi ^a   Gribble, Gordon W ^a   Sporn, Michael B ^a   Letterio, John J ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 (2 CYANO 3,12 DIOXOOLEANA 1,9 DIEN 28 OYL) IMIDAZOLE; 1-(2-CYANO-3,12-DIOXOOLEANA-1,9-DIEN-28-OYL) IMIDAZOLE; DRUG DERIVATIVE; IMIDAZOLE DERIVATIVE; INTERLEUKIN 6; OLEANOLIC ACID; STAT PROTEIN; STAT5 PROTEIN;

APOPTOSIS; ARTICLE; CELL PROLIFERATION; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; HUMAN; IMMUNOBLOTTING; LUNG TUMOR; METABOLISM; MULTIPLE MYELOMA; PHOSPHORYLATION; SIGNAL TRANSDUCTION; TIME; TUMOR CELL LINE;

APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMIDAZOLES; IMMUNOBLOTTING; INTERLEUKIN-6; LUNG NEOPLASMS; MULTIPLE MYELOMA; OLEANOLIC ACID; PHOSPHORYLATION; SIGNAL TRANSDUCTION; STAT TRANSCRIPTION FACTORS; STAT5 TRANSCRIPTION FACTOR; TIME FACTORS; TRANSCRIPTION, GENETIC;

EID: 33750976014     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-06-0215     Document Type: Article

References (0)