The novel triterpenoid CDDO induces apoptosis and differentiation of human osteosarcoma cells by a caspase-8 dependent mechanism

Molecular Pharmacology

Volumn 59, Issue 5, 2001, Pages 1094-1099

  Ito, Yasumasa ^a   Pandey, Pramod ^a   Sporn, Michael B ^b   Datta, Rakesh ^a   Kharbanda, Surender ^a   Kufe, Donald ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b DARTMOUTH MEDICAL SCHOOL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 CYANO 3,12 DIOXOOLEANA 1,9 DIEN 28 OIC ACID; ALKALINE PHOSPHATASE; CASPASE 3; CYTOCHROME C; DNA FRAGMENT; OSTEOCALCIN; PROTEIN BCL X; TRITERPENE DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME MECHANISM; HUMAN; HUMAN CELL; OSTEOBLAST; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

EID: 0035037586     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.59.5.1094     Document Type: Article

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