Isotopic non-stationary 13C gluconate tracer method for accurate determination of the pentose phosphate pathway split-ratio in Penicillium chrysogenum

Metabolic Engineering

Volumn 10, Issue 3-4, 2008, Pages 178-186

  Zhao, Zheng ^a   Kuijvenhoven, Karel ^a   Ras, Cor ^a   van Gulik, Walter M ^a   Heijnen, Joseph J ^a   Verheijen, Peter J T ^a   van Winden, Wouter A ^a  

^a DELFT UNIVERSITY OF TECHNOLOGY   (Netherlands)

Author keywords

Isotopic non stationary 13C flux analysis; Metabolic engineering; Metabolic flux ratio analysis; Pentose phosphate pathway; Statistical analysis

Indexed keywords

NON STATIONARY;

ISOTOPES;

CARBON 13; GLUCONIC ACID; PENICILLIN G; PENTOSE PHOSPHATE; PHOSPHOGLUCONATE; TRACER;

AEROBIC METABOLISM; ARTICLE; CELL DENSITY; CELL FRACTIONATION; CHEMOSTAT; DILUTION; ISOTOPE LABELING; ISOTOPIC NON STATIONARY GLUCONATE TRACER METHOD; MATHEMATICAL COMPUTING; METABOLIC ACTIVATION; METABOLIC FLUX ANALYSIS; METABOLITE; NONHUMAN; PENICILLIUM CHRYSOGENUM; PENTOSE PHOSPHATE CYCLE; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE;

ALGORITHMS; CARBON RADIOISOTOPES; COMPUTER SIMULATION; FUNGAL PROTEINS; ISOTOPE LABELING; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, CHEMICAL; MODELS, MOLECULAR; PENICILLIUM CHRYSOGENUM; PENTOSE PHOSPHATE PATHWAY; SENSITIVITY AND SPECIFICITY; SIGNAL TRANSDUCTION;

PENICILLIUM CHRYSOGENUM;

EID: 44849135488     PISSN: 10967176     EISSN: 10967184     Source Type: Journal    
DOI: 10.1016/j.ymben.2008.04.003     Document Type: Article

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