Nontargeted elucidation of metabolic pathways using stable-isotope tracers and mass spectrometry

Analytical Chemistry

Volumn 82, Issue 15, 2010, Pages 6621-6628

  Hiller, Karsten ^a   Metallo, Christian M ^a   Kelleher, Joanne K ^a   Stephanopoulos, Gregory ^a  

^a Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APRIORI; COMPOUND LIBRARIES; COMPUTATIONAL ANALYSIS; GLOBAL ANALYSIS; HIGH-THROUGHPUT; ISOTOPE TRACERS; ISOTOPOMER DISTRIBUTIONS; METABOLIC FLUX; METABOLIC NETWORK; METABOLIC PATHWAYS; METABOLOMICS; MINIMAL INFORMATION; NEW DIMENSIONS; NON-TARGETED; NOVEL METHODS; QUANTITATIVE ANALYSIS; QUANTITATIVE DETECTION; REACTION NETWORK; STABLE ISOTOPE TRACERS; SYSTEMS LEVELS;

BIOMOLECULES; INDUSTRIAL APPLICATIONS; ISOTOPES; MASS SPECTROMETRY; METABOLITES;

METABOLISM;

GLUTAMINE;

ALGORITHM; CHEMISTRY; CONFERENCE PAPER; HUMAN; ISOTOPE LABELING; MASS FRAGMENTOGRAPHY; METABOLISM; METABOLOMICS; METHODOLOGY; TUMOR CELL LINE;

ALGORITHMS; CELL LINE, TUMOR; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; GLUTAMINE; HUMANS; ISOTOPE LABELING; METABOLIC NETWORKS AND PATHWAYS; METABOLOMICS;

EID: 77955169879     PISSN: 00032700     EISSN: None     Source Type: Journal    
DOI: 10.1021/ac1011574     Document Type: Conference Paper

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