Metabolite and isotopomer balancing in the analysis of metabolic cycles: I. Theory

Biotechnology and Bioengineering

Volumn 62, Issue 4, 1999, Pages 375-391

  Klapa, Maria I ^a   Park, Sung M ^a   Sinskey, Anthony J ^b   Stephanopoulos, Gregory ^a  

^a Massachusetts Institute of Technology   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

13C NMR; GC MS; Isotopomer analysis; Metabolic flux analysis; TCA cycle

Indexed keywords

CARBOXYLIC ACIDS; GAS CHROMATOGRAPHY; ISOTOPES; MASS SPECTROMETRY; MATHEMATICAL MODELS; METABOLITES; MOLECULAR WEIGHT DISTRIBUTION; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; SUBSTRATES;

ISOTOPOMER ANALYSIS; METABOLIC FLUX ANALYSIS; TRICARBOXYLIC ACID;

METABOLISM;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CITRIC ACID CYCLE; GAS CHROMATOGRAPHY; ISOTOPE LABELING; MASS SPECTROMETRY; MOLECULAR DYNAMICS; MOLECULAR MODEL; MOLECULAR WEIGHT;

EID: 0033585824     PISSN: 00063592     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0290(19990220)62:4<375::AID-BIT1>3.0.CO;2-O     Document Type: Article

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