메뉴 건너뛰기




Volumn 101, Issue 3, 2011, Pages 631-642

Models of HERG gating

Author keywords

[No Author keywords available]

Indexed keywords

ERG1 POTASSIUM CHANNEL; POTASSIUM CHANNEL HERG;

EID: 80052494606     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2011.06.050     Document Type: Article
Times cited : (36)

References (61)
  • 1
    • 0029002969 scopus 로고
    • A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel
    • M.C. Sanguinetti, and C. Jiang M.T. Keating A mechanistic link between an inherited and an acquired cardiac arrhythmia: HERG encodes the IKr potassium channel Cell 81 1995 299 307
    • (1995) Cell , vol.81 , pp. 299-307
    • Sanguinetti, M.C.1    Jiang, C.2    Keating, M.T.3
  • 2
    • 0029007356 scopus 로고
    • HERG, a human inward rectifier in the voltage-gated potassium channel family
    • M.C. Trudeau, and J.W. Warmke G.A. Robertson HERG, a human inward rectifier in the voltage-gated potassium channel family Science 269 1995 92 95
    • (1995) Science , vol.269 , pp. 92-95
    • Trudeau, M.C.1    Warmke, J.W.2    Robertson, G.A.3
  • 4
    • 0028914969 scopus 로고
    • A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome
    • M.E. Curran, and I. Splawski M.T. Keating A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome Cell 80 1995 795 803
    • (1995) Cell , vol.80 , pp. 795-803
    • Curran, M.E.1    Splawski, I.2    Keating, M.T.3
  • 5
    • 0034112322 scopus 로고    scopus 로고
    • Long QT syndrome
    • G.M. Vincent Long QT syndrome Cardiol. Clin. 18 2000 309 325
    • (2000) Cardiol. Clin. , vol.18 , pp. 309-325
    • Vincent, G.M.1
  • 7
    • 34248567830 scopus 로고    scopus 로고
    • Suppression of cellular alternans in guinea pig ventricular myocytes with LQT2; Insights from the luo-rudy model
    • DOI 10.1142/S0218127407017355, PII S0218127407017355
    • V.E. Bondarenko, and R.L. Rasmusson Suppression of cellular alternans in guinea-pig ventricular myocytes with LQT2: insights from the Luo-Rudy model Int. J. Bifurcat. Chaos 17 2007 381 425 (Pubitemid 46752992)
    • (2007) International Journal of Bifurcation and Chaos , vol.17 , Issue.2 , pp. 381-425
    • Bondarenko, V.E.1    Rasmusson, R.L.2
  • 8
    • 34548482933 scopus 로고    scopus 로고
    • Simulations of propagated mouse ventricular action potentials: Effects of molecular heterogeneity
    • V.E. Bondarenko, and R.L. Rasmusson Simulations of propagated mouse ventricular action potentials: effects of molecular heterogeneity Am. J. Physiol. Heart Circ. Physiol. 293 2007 H1816 H1832
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.293
    • Bondarenko, V.E.1    Rasmusson, R.L.2
  • 11
    • 0032763731 scopus 로고    scopus 로고
    • 2+ dynamics and the stability of ventricular tachycardia
    • 2+ dynamics and the stability of ventricular tachycardia Biophys. J. 77 1999 2930 2941
    • (1999) Biophys. J. , vol.77 , pp. 2930-2941
    • Chudin, E.1    Goldhaber, J.2    Kogan, B.3
  • 12
    • 33750856807 scopus 로고    scopus 로고
    • Ionic mechanisms underlying human atrial action potential properties: Insights from a mathematical model
    • M. Courtemanche, R.J. Ramirez, and S. Nattel Ionic mechanisms underlying human atrial action potential properties: insights from a mathematical model Am. J. Physiol. 275 1998 H301 H321
    • (1998) Am. J. Physiol. , vol.275
    • Courtemanche, M.1    Ramirez, R.J.2    Nattel, S.3
  • 13
    • 0034026881 scopus 로고    scopus 로고
    • +](i) overloaded cardiac myocytes: A simulation study
    • i overloaded cardiac myocytes: a simulation study Biophys. J. 78 2000 2392 2404 (Pubitemid 30313797)
    • (2000) Biophysical Journal , vol.78 , Issue.5 , pp. 2392-2404
    • Faber, G.M.1    Rudy, Y.2
  • 16
    • 73049094376 scopus 로고    scopus 로고
    • A novel computational model of the human ventricular action potential and Ca transient
    • E. Grandi, F.S. Pasqualini, and D.M. Bers A novel computational model of the human ventricular action potential and Ca transient J. Mol. Cell. Cardiol. 48 2010 112 121
    • (2010) J. Mol. Cell. Cardiol. , vol.48 , pp. 112-121
    • Grandi, E.1    Pasqualini, F.S.2    Bers, D.M.3
  • 17
    • 1842430979 scopus 로고    scopus 로고
    • The role of M cells and the long QT syndrome in cardiac arrhythmias: Simulation studies of reentrant excitations using a detailed electrophysiological model
    • DOI 10.1063/1.1636272
    • H. Henry, and W.J. Rappel The role of M cells and the long QT syndrome in cardiac arrhythmias: simulation studies of reentrant excitations using a detailed electrophysiological model Chaos 14 2004 172 182 (Pubitemid 38430249)
    • (2004) Chaos , vol.14 , Issue.1 , pp. 172-182
    • Henry, H.1    Rappel, W.-J.2
  • 18
    • 78650717034 scopus 로고    scopus 로고
    • A major role for HERG in determining frequency of reentry in neonatal rat ventricular myocyte monolayer
    • L. Hou, and M. Deo J. Jalife A major role for HERG in determining frequency of reentry in neonatal rat ventricular myocyte monolayer Circ. Res. 107 2010 1503 1511
    • (2010) Circ. Res. , vol.107 , pp. 1503-1511
    • Hou, L.1    Deo, M.2    Jalife, J.3
  • 19
    • 56349090390 scopus 로고    scopus 로고
    • Tachycardia-induced early afterdepolarizations: Insights into potential ionic mechanisms from computer simulations
    • R.B. Huffaker, and R. Samade B. Kogan Tachycardia-induced early afterdepolarizations: insights into potential ionic mechanisms from computer simulations Comput. Biol. Med. 38 2008 1140 1151
    • (2008) Comput. Biol. Med. , vol.38 , pp. 1140-1151
    • Huffaker, R.B.1    Samade, R.2    Kogan, B.3
  • 20
    • 50449107767 scopus 로고    scopus 로고
    • Na remodeling after myocardial infarction: Insights from mathematical modeling
    • Na remodeling after myocardial infarction: insights from mathematical modeling J. Mol. Cell. Cardiol. 45 2008 420 428
    • (2008) J. Mol. Cell. Cardiol. , vol.45 , pp. 420-428
    • Hund, T.J.1    Decker, K.F.2    Rudy, Y.3
  • 21
    • 8744246332 scopus 로고    scopus 로고
    • Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model
    • DOI 10.1161/01.CIR.0000147231.69595.D3
    • T.J. Hund, and Y. Rudy Rate dependence and regulation of action potential and calcium transient in a canine cardiac ventricular cell model Circulation 110 2004 3168 3174 (Pubitemid 39525061)
    • (2004) Circulation , vol.110 , Issue.20 , pp. 3168-3174
    • Hund, T.J.1    Rudy, Y.2
  • 22
    • 4444320725 scopus 로고    scopus 로고
    • A computational model of the human left-ventricular epicardial myocyte
    • DOI 10.1529/biophysj.104.043299
    • V. Iyer, R. Mazhari, and R.L. Winslow A computational model of the human left-ventricular epicardial myocyte Biophys. J. 87 2004 1507 1525 (Pubitemid 39167010)
    • (2004) Biophysical Journal , vol.87 , Issue.3 , pp. 1507-1525
    • Iyer, V.1    Mazhari, R.2    Winslow, R.L.3
  • 23
    • 61549114668 scopus 로고    scopus 로고
    • Model of excitation-contraction coupling of rat neonatal ventricular myocytes
    • T. Korhonen, S.L. Hänninen, and P. Tavi Model of excitation-contraction coupling of rat neonatal ventricular myocytes Biophys. J. 96 2009 1189 1209
    • (2009) Biophys. J. , vol.96 , pp. 1189-1209
    • Korhonen, T.1    Hänninen, S.L.2    Tavi, P.3
  • 24
    • 77749322248 scopus 로고    scopus 로고
    • Kr and modulates cardiac action potential characteristics
    • Kr and modulates cardiac action potential characteristics PLoS ONE 5 2010 e9021
    • (2010) PLoS ONE , vol.5 , pp. 9021
    • Larsen, A.P.1    Olesen, S.P.2
  • 26
    • 38349013614 scopus 로고    scopus 로고
    • A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates
    • A. Mahajan, and Y. Shiferaw J.N. Weiss A rabbit ventricular action potential model replicating cardiac dynamics at rapid heart rates Biophys. J. 94 2008 392 410
    • (2008) Biophys. J. , vol.94 , pp. 392-410
    • Mahajan, A.1    Shiferaw, Y.2    Weiss, J.N.3
  • 27
    • 43049164191 scopus 로고    scopus 로고
    • A model of the guinea-pig ventricular cardiac myocyte incorporating a transverse-axial tubular system
    • DOI 10.1016/j.pbiomolbio.2007.07.022, PII S0079610707000624
    • M. Pásek, and J. Simurda G. Christé A model of the guinea-pig ventricular cardiac myocyte incorporating a transverse-axial tubular system Prog. Biophys. Mol. Biol. 96 2008 258 280 (Pubitemid 351635625)
    • (2008) Progress in Biophysics and Molecular Biology , vol.96 , Issue.1-3 , pp. 258-280
    • Pasek, M.1    Simurda, J.2    Orchard, C.H.3    Christe, G.4
  • 28
    • 42649132823 scopus 로고    scopus 로고
    • Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model
    • T. Peitersen, and M. Grunnet S.P. Olesen Computational analysis of the effects of the hERG channel opener NS1643 in a human ventricular cell model Heart Rhythm 5 2008 734 741
    • (2008) Heart Rhythm , vol.5 , pp. 734-741
    • Peitersen, T.1    Grunnet, M.2    Olesen, S.P.3
  • 29
    • 0035658721 scopus 로고    scopus 로고
    • LabHEART: An interactive computer model of rabbit ventricular myocyte ion channels and Ca transport
    • J.L. Puglisi, and D.M. Bers LabHEART: an interactive computer model of rabbit ventricular myocyte ion channels and Ca transport Am. J. Physiol. Cell Physiol. 281 2001 C2049 C2060
    • (2001) Am. J. Physiol. Cell Physiol. , vol.281
    • Puglisi, J.L.1    Bers, D.M.2
  • 30
    • 77954742469 scopus 로고    scopus 로고
    • A computational model of Purkinje fiber single cell electrophysiology: Implications for the long QT syndrome
    • K.J. Sampson, and V. Iyer R.S. Kass A computational model of Purkinje fiber single cell electrophysiology: implications for the long QT syndrome J. Physiol. 588 2010 2643 2655
    • (2010) J. Physiol. , vol.588 , pp. 2643-2655
    • Sampson, K.J.1    Iyer, V.2    Kass, R.S.3
  • 31
    • 78049436203 scopus 로고    scopus 로고
    • Regression analysis for constraining free parameters in electrophysiological models of cardiac cells
    • A.X. Sarkar, and E.A. Sobie Regression analysis for constraining free parameters in electrophysiological models of cardiac cells PLOS Comput. Biol. 6 2010 e1000914
    • (2010) PLOS Comput. Biol. , vol.6 , pp. 1000914
    • Sarkar, A.X.1    Sobie, E.A.2
  • 32
    • 43449088837 scopus 로고    scopus 로고
    • Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2
    • C. Sims, and S. Reisenweber G. Salama Sex, age, and regional differences in L-type calcium current are important determinants of arrhythmia phenotype in rabbit hearts with drug-induced long QT type 2 Circ. Res. 102 2008 e86 e100
    • (2008) Circ. Res. , vol.102
    • Sims, C.1    Reisenweber, S.2    Salama, G.3
  • 33
    • 50049127535 scopus 로고    scopus 로고
    • In silico risk assessment for drug-induction of cardiac arrhythmia
    • S. Suzuki, and S. Murakami Y. Kurachi In silico risk assessment for drug-induction of cardiac arrhythmia Prog. Biophys. Mol. Biol. 98 2008 52 60
    • (2008) Prog. Biophys. Mol. Biol. , vol.98 , pp. 52-60
    • Suzuki, S.1    Murakami, S.2    Kurachi, Y.3
  • 34
    • 28344435526 scopus 로고    scopus 로고
    • Comparison of electrophysiological models for human ventricular cells and tissues
    • DOI 10.1016/j.pbiomolbio.2005.05.015, PII S0079610705000301, From Funny Current to Current Physiome
    • K.H. Ten Tusscher, and O. Bernus A.V. Panfilov Comparison of electrophysiological models for human ventricular cells and tissues Prog. Biophys. Mol. Biol. 90 2006 326 345 (Pubitemid 41721057)
    • (2006) Progress in Biophysics and Molecular Biology , vol.90 , Issue.1-3 , pp. 326-345
    • Ten Tusscher, K.H.W.J.1    Bernus, O.2    Hren, R.3    Panfilov, A.V.4
  • 37
    • 0033545725 scopus 로고    scopus 로고
    • Effects of I(Kr) and I(Ks) heterogeneity on action potential duration and its rate dependence: A simulation study
    • Ks heterogeneity on action potential duration and its rate dependence: a simulation study Circulation 99 1999 2466 2474 (Pubitemid 29218245)
    • (1999) Circulation , vol.99 , Issue.18 , pp. 2466-2474
    • Viswanathan, P.C.1    Shaw, R.M.2    Rudy, Y.3
  • 38
    • 76749160779 scopus 로고    scopus 로고
    • Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: A simulation study
    • P.C. Yang, and J. Kurokawa C.E. Clancy Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: a simulation study PLOS Comput. Biol. 6 2010 e1000658
    • (2010) PLOS Comput. Biol. , vol.6 , pp. 1000658
    • Yang, P.C.1    Kurokawa, J.2    Clancy, C.E.3
  • 39
    • 6044255042 scopus 로고    scopus 로고
    • In silico study of action potential and QT interval shortening due to loss of inactivation of the cardiac rapid delayed rectifier potassium current
    • DOI 10.1016/j.bbrc.2004.07.176, PII S0006291X04016201
    • H. Zhang, and J.C. Hancox In silico study of action potential and QT interval shortening due to loss of inactivation of the cardiac rapid delayed rectifier potassium current Biochem. Biophys. Res. Commun. 322 2004 693 699 (Pubitemid 39490358)
    • (2004) Biochemical and Biophysical Research Communications , vol.322 , Issue.2 , pp. 693-699
    • Zhang, H.1    Hancox, J.C.2
  • 41
    • 0030025308 scopus 로고    scopus 로고
    • The inward rectification mechanism of the HERG cardiac potassium channel
    • DOI 10.1038/379833a0
    • P.L. Smith, T. Baukrowitz, and G. Yellen The inward rectification mechanism of the HERG cardiac potassium channel Nature 379 1996 833 836 (Pubitemid 26067726)
    • (1996) Nature , vol.379 , Issue.6568 , pp. 833-836
    • Smith, P.L.1    Baukrowitz, T.2    Yellen, G.3
  • 43
    • 0030819954 scopus 로고    scopus 로고
    • A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes
    • DOI 10.1111/j.1469-7793.1997.045bl.x
    • S. Wang, and S. Liu R.L. Rasmusson A quantitative analysis of the activation and inactivation kinetics of HERG expressed in Xenopus oocytes J. Physiol. 502 1997 45 60 (Pubitemid 27322975)
    • (1997) Journal of Physiology , vol.502 , Issue.1 , pp. 45-60
    • Wang, S.1    Liu, S.2    Morales, M.J.3    Strauss, H.C.4    Rasmusson, R.L.5
  • 44
    • 0027984375 scopus 로고
    • Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification
    • DOI 10.1038/372366a0
    • A.N. Lopatin, E.N. Makhina, and C.G. Nichols Potassium channel block by cytoplasmic polyamines as the mechanism of intrinsic rectification Nature 372 1994 366 369 (Pubitemid 24363439)
    • (1994) Nature , vol.372 , Issue.6504 , pp. 366-369
    • Lopatin, A.N.1    Makhina, E.N.2    Nichols, C.G.3
  • 48
    • 0030049457 scopus 로고    scopus 로고
    • Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes
    • S. Liu, and R.L. Rasmusson H.C. Strauss Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes Biophys. J. 70 1996 2704 2715 (Pubitemid 26000969)
    • (1996) Biophysical Journal , vol.70 , Issue.6 , pp. 2704-2715
    • Liu, S.1    Rasmusson, R.L.2    Campbell, D.L.3    Wang, S.4    Strauss, H.C.5
  • 49
    • 35649001607 scopus 로고
    • A quantitative description of membrane current and its application to conduction and excitation in nerve
    • A.L. Hodgkin, and A.F. Huxley A quantitative description of membrane current and its application to conduction and excitation in nerve J. Physiol. 117 1952 500 544
    • (1952) J. Physiol. , vol.117 , pp. 500-544
    • Hodgkin, A.L.1    Huxley, A.F.2
  • 50
    • 0029024749 scopus 로고
    • + current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization
    • + current in ventricular myocytes of the guinea pig type. Theoretical formulation and their role in repolarization Circ. Res. 77 1995 140 152
    • (1995) Circ. Res. , vol.77 , pp. 140-152
    • Zeng, J.1    Laurita, K.R.2    Rudy, Y.3
  • 51
    • 0035028582 scopus 로고    scopus 로고
    • Cellular consequences of HERG mutations in the long QT syndrome: Precursors to sudden cardiac death
    • DOI 10.1016/S0008-6363(00)00293-5, PII S0008636300002935
    • C.E. Clancy, and Y. Rudy Cellular consequences of HERG mutations in the long QT syndrome: precursors to sudden cardiac death Cardiovasc. Res. 50 2001 301 313 (Pubitemid 32382157)
    • (2001) Cardiovascular Research , vol.50 , Issue.2 , pp. 301-313
    • Clancy, C.E.1    Rudy, Y.2
  • 52
    • 0035816728 scopus 로고    scopus 로고
    • Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis
    • R. Mazhari, and J.L. Greenstein H.B. Nuss Molecular interactions between two long-QT syndrome gene products, HERG and KCNE2, rationalized by in vitro and in silico analysis Circ. Res. 89 2001 33 38 (Pubitemid 34135489)
    • (2001) Circulation Research , vol.89 , Issue.1 , pp. 33-38
    • Mazhari, R.1    Greenstein, J.L.2    Winslow, R.L.3    Marban, E.4    Nuss, H.B.5
  • 54
    • 0021086246 scopus 로고
    • A reinterpretation of mammalian sodium channel gating based on single channel recording
    • R.W. Aldrich, D.P. Corey, and C.F. Stevens A reinterpretation of mammalian sodium channel gating based on single channel recording Nature 306 1983 436 441 (Pubitemid 14235560)
    • (1983) Nature , vol.306 , Issue.5942 , pp. 436-441
    • Aldrich, R.W.1    Corey, D.P.2    Stevens, C.F.3
  • 56
    • 0028855945 scopus 로고
    • A quantitative description of the E-4031-sensitive repolarization current in rabbit ventricular myocytes
    • J.R. Clay, and A. Ogbaghebriel A. Shrier A quantitative description of the E-4031-sensitive repolarization current in rabbit ventricular myocytes Biophys. J. 69 1995 1830 1837
    • (1995) Biophys. J. , vol.69 , pp. 1830-1837
    • Clay, J.R.1    Ogbaghebriel, A.2    Shrier, A.3
  • 59
    • 0030900902 scopus 로고    scopus 로고
    • Hodgkin-Huxley and partially coupled inactivation models yield different voltage dependence of block
    • S. Liu, and R.L. Rasmusson Hodgkin-Huxley and partially coupled inactivation models yield different voltage dependence of block Am. J. Physiol. 272 1997 H2013 H2022
    • (1997) Am. J. Physiol. , vol.272
    • Liu, S.1    Rasmusson, R.L.2
  • 61
    • 78651226179 scopus 로고    scopus 로고
    • A model of the interaction between N-type and C-type inactivation in Kv1.4 channels
    • G.C. Bett, and I. Dinga-Madou R.L. Rasmusson A model of the interaction between N-type and C-type inactivation in Kv1.4 channels Biophys. J. 100 2011 11 21
    • (2011) Biophys. J. , vol.100 , pp. 11-21
    • Bett, G.C.1    Dinga-Madou, I.2    Rasmusson, R.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.