Activation and inactivation kinetics of an E-4031-sensitive current from single ferret atrial myocytes

Biophysical Journal

Volumn 70, Issue 6, 1996, Pages 2704-2715

  Liu, Shuguang ^a   Rasmusson, Randall L ^a,b   Campbell, Donald L ^a   Wang, Shimin ^a   Strauss, Harold C ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

^b Duke University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; POTASSIUM CHANNEL;

ANIMAL CELL; ARTICLE; CHANNEL GATING; FERRET; HEART ATRIUM CONTRACTION; HEART MUSCLE CELL; NONHUMAN; POTASSIUM CURRENT;

EID: 0030049457     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(96)79840-5     Document Type: Article

References (45)

1. Aldrich, R. W., D. P. Corey, and C. F. Stevens. 1983. A reinterpretation of mammalian sodium channel gating based on single channel recording. Nature. 306:436-441.
2. Aldrich, R. W., and C. F. Stevens. 1987. Voltage dependent gating of single sodium channels from mammalian neuroblastoma cells. J. Neurosci. 7:418-431.
3. Anumonwo, J. M. B., L. C. Freeman, W. M. Kwok, and R. S. Kass. 1992. Delayed rectification in single cells isolated from guinea pig sinoatrial node. Am. J. Physiol. 262:H921-H925.
4. + currents in isolated rat ventricular myocytes. J. Gen. Physiol. 97:973-1011.
5. + induced anomalous rectification in squid giant axons. J. Gen. Physiol. 50:491-503.
6. Backx, P. M., and E. Marban. 1993. Background potassium current active during the plateau of the action potential in guinea pig ventricular myocytes. Circ. Res. 72:890-900.
7. Balser, J. R., P. B. Bennett, and D. M. Roden. 1990. Time-dependent outward current in guinea pig ventricular myocytes. J. Gen. Physiol. 96:835-863.
8. + currents in isolated human ventricular myocytes from patients with terminal heart failure. Circ. Res. 73:379-385.
9. Campbell, D. L., R. L. Rasmusson, Y. Qu, and H. C. Strauss. 1993. The calcium-independent transient outward potassium current in isolated ferret right ventricular myocytes. J. Gen. Physiol. 101:571-601.
10. Campbell, D. L., R. L. Rasmusson, and H. C. Strauss. 1992. Ionic current mechanisms generating vertebrate primary pacemaker activity at the single cell level: an integrative view. Annu. Rev. Physiol. 54:279-302.
11. + current in cardiac myocytes by dofetilide. J. Pharmacol. Exp. Ther. 262:809-817.
12. + current by amokalant in rabbit ventricular myocytes. Circ. Res. 73:857-868.
13. Castellino, R. C., M. J. Morales, H. C. Strauss, and R. L. Rasmusson. 1995. Time- and voltage-dependent modulation of a Kv1.4 channel by a β-subunit (Kvβ3) cloned from ferret ventricle. Am. J. Physiol. 269(Heart Circ. Physiol. 38):H385-H391.
14. Clay, J. R., A. Ogbaghebriel, T. Paquette, B. I. Sasyniuk, and A. Shrier. 1995. A quantitative description of the E-4031 sensitive repolarization current in rabbit ventricular myocytes. Biophys. J. 69:1830-1837.
15. Cole, K. S., and J. W. Moore. 1960. Potassium ion current in the squid giant axon. Dynamic characteristics. Biophys. J. 1:1-14.
16. Coraboeuf, E., and E. Carmeliet. 1982. Existence of two transient outward currents in sheep Purkinje fibers. Pflugers Arch. 392:352-359.
17. Curran, M. E., I. Splawski, K. W. Timothy, G. M. Vincent. E. D. Green, and M. T. Keating. 1995. A molecular basis for cardiac arrhythmia: HERG mutations cause long QT syndrome. Cell. 80:795-803.
18. f. Origins and developments. Prog. Biophys. Mol. Biol. 46:163-183.
19. + channel current. Circ. Res. 73:210-216.
20. Hille, B. 1992. Ionic Channels of Excitable Membranes, 2nd ed. Sinauer Associates, Sunderland, MA.
21. Hodgkin, A. L., and A. F. Huxley. 1952. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117:500-544.
22. Hoshi, T., W. N. Zaggotta, and R. W. Aldrich, 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science. 250:533-538.
23. 2+. Am. J. Physiol. 264:C1434-C1438.
24. + current by dofetilide. Circ. Res. 72:75-83.
25. Kass, R. S. 1995. Delayed potassium channels in the heart: cellular, molecular, and regulatory properties. In Cardiac Electrophysiology: From Cell to Bedside, 2nd ed. D. P. Zipes and J. Jalife, editors. W. B. Saunders, Philadelphia. 74-82.
26. Kr) from single ferret atrial myocytes. Biophys. J. 70:A399.
27. McAllister, R. E., D. Noble, and R. W. Tsien. 1975. Reconstruction of the electrical activity of cardiac Purkinje fibers. J. Physiol. (Lond.). 251: 1-59.
28. Muraki, K., Y. Imaizumi, M. Watanabe, Y. Habuchi, and W. R. Giles. 1995. Delayed rectifier K+ current in rabbit atrial muscle. Am. J. Physiol. 269(Heart Circ. Physiol. 38):H524-H532.
29. Noble, D. 1984. The surprising heart: a review of recent progress in cardiac electrophysiology. J. Physiol. (Lond.). 353:1-50.
30. Noble, D., and R. W. Tsien. 1968. The kinetics and rectifier properties of the slow potassium current in cardiac Purkinje fibers. J. Physiol. (Lond.). 195:185-214.
31. Noble, D., and R. W. Tsien. 1969. Outward membrane currents activated in the plateau range of potentials in cardiac Purkinje fibers. J. Physiol. (Lond.). 200:205-231.
32. Kr potassium channel. Cell. 81: 299-307.
33. + current. Differential sensitivity to block by class III antiarrhythmic agents. J. Gen. Physiol 96:195-215.
34. + current is composed of two currents in guinea pig atrial cells. Am. J. Physiol. 260:H393-H399.
35. + currents. Pflügers Arch. 420:180-186.
36. Shibasaki, T. 1987. Conductance and kinetics of delayed rectifier potassium channels in nodal cells of the rabbit heart. J. Physiol. (Lond.). 387:227-250.
37. Shibata, E. F., and W. R. Giles. 1985. Ionic currents which generate the spontaneous diastolic depolarizations in individual cardiac pacemaker cells. Proc. Natl. Acad. Sci. USA. 82:7796-7800.
38. Snyders, D. J., M. M. Tamkun, and P. B. Bennett. 1993. A rapidly activating and slowly inactivating potassium channel cloned from human heart. J. Gen. Physiol. 101:513-543.
39. Trudeau, M. C., J. W. Warmke, B. Ganetzky, and G. A. Robertson. 1995. HERG, a human inward rectifier in the voltage-gated potassium channel family. Science. 269:92-95.
40. Verheijck, E. E., A. C. G. van Ginneken, J. Bourier, and L. N. Bouman. 1995, Effects of delayed rectifier current blockade by E-4031 on impulse generation in single sinoatrial nodal myocytes of the rabbit. Circ. Res. 76:607-615.
41. Wang, Q., B. Fermini, and S. Nattel. 1993. Delayed rectifier outward current and repolarization in human atrial myocytes. Circ. Res. 73: 276-285.
42. Wang, S., M. J. Morales, S. Liu, H. C. Strauss, and R. L. Rasmusson. 1996. Instantaneous and time-dependent components of rectification of h-erg expressed in Xenopus oocytes. Biophys. J. 70:A312.
43. Wang, Z., B. Fermini, and S. Nattel. 1994. Rapid and slow components of delayed rectifier current in human atrial myocytes. Cardiovasc. Res. 28:1540-1546.
44. Zaggotta, W. N., and R. W. Aldrich. 1990. Voltage-dependent gating of Shaker A-type potassium channels in Drosophila muscle. J. Gen. Physiol. 95:25-60.
45. + current in ventricular myocytes of the guinea pig type. Circ. Res. 77:140-152.