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Volumn 99, Issue 18, 1999, Pages 2466-2474

Effects of I(Kr) and I(Ks) heterogeneity on action potential duration and its rate dependence: A simulation study

Author keywords

Action potentials; Arrhythmia; Calcium channels; Conduction; Potassium

Indexed keywords

CALCIUM CHANNEL; POTASSIUM; POTASSIUM CHANNEL; SODIUM;

EID: 0033545725     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.99.18.2466     Document Type: Article
Times cited : (313)

References (29)
  • 1
    • 0024433094 scopus 로고
    • Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: Role of the transient outward current
    • Litovsky SH, Antzelevitch C. Rate dependence of action potential duration and refractoriness in canine ventricular endocardium differs from that of epicardium: role of the transient outward current. J Am Coll Cardiol. 1989;14:1053-1066.
    • (1989) J Am Coll Cardiol. , vol.14 , pp. 1053-1066
    • Litovsky, S.H.1    Antzelevitch, C.2
  • 2
    • 0001740880 scopus 로고    scopus 로고
    • Larger late sodium current contributes to the longer action potential of the M-cell in canine ventricular myocardium
    • Eddlestone GT, Zygmont AC, Antzelevitch C. Larger late sodium current contributes to the longer action potential of the M-cell in canine ventricular myocardium. PACE. 1996;19:569. Abstract.
    • (1996) PACE , vol.19 , pp. 569
    • Eddlestone, G.T.1    Zygmont, A.C.2    Antzelevitch, C.3
  • 3
    • 0028881535 scopus 로고
    • Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes: A weaker IKs contributes to the longer action potential of the M cell
    • Liu DW, Antzelevitch C. Characteristics of the delayed rectifier current (IKr and IKs) in canine ventricular epicardial, midmyocardial, and endocardial myocytes: a weaker IKs contributes to the longer action potential of the M cell. Circ Res. 1995;76:351-365.
    • (1995) Circ Res. , vol.76 , pp. 351-365
    • Liu, D.W.1    Antzelevitch, C.2
  • 4
    • 0031007731 scopus 로고    scopus 로고
    • Regional localization of ERG, the channel protein responsible for the rapid component of the delayed rectifier. K+ current in the ferret heart
    • Brahmajothi MV, Morales MJ, Reimer KA, Strauss HC. Regional localization of ERG, the channel protein responsible for the rapid component of the delayed rectifier. K+ current in the ferret heart. Circ Res. 1997; 81:128-135.
    • (1997) Circ Res. , vol.81 , pp. 128-135
    • Brahmajothi, M.V.1    Morales, M.J.2    Reimer, K.A.3    Strauss, H.C.4
  • 6
    • 0025829410 scopus 로고
    • A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle: The M cell
    • Sicouri S, Antzelevitch C. A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle: the M cell. Circ Res. 1991;68:1729-1741.
    • (1991) Circ Res. , vol.68 , pp. 1729-1741
    • Sicouri, S.1    Antzelevitch, C.2
  • 7
    • 0029023244 scopus 로고
    • Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: Evidence for presence of M cells
    • Drouin E, Charpentier F, Gauthier C, Laurent K, Le Marec H. Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells. J Am Coll Cardiol. 1995;26:185-192.
    • (1995) J Am Coll Cardiol. , vol.26 , pp. 185-192
    • Drouin, E.1    Charpentier, F.2    Gauthier, C.3    Laurent, K.4    Le Marec, H.5
  • 8
    • 0027330110 scopus 로고
    • Drug-induced afterdepolarizations and triggered activity occur in a discrete subpopulation of ventricular muscle cells (M cells) in the canine heart: Quinidine and digitalis
    • Sicouri S, Antzelevitch C. Drug-induced afterdepolarizations and triggered activity occur in a discrete subpopulation of ventricular muscle cells (M cells) in the canine heart: quinidine and digitalis. J Cardiovasc Electrophysiol. 1993;4:48-58.
    • (1993) J Cardiovasc Electrophysiol. , vol.4 , pp. 48-58
    • Sicouri, S.1    Antzelevitch, C.2
  • 9
    • 0025351245 scopus 로고
    • Two components of cardiac delayed rectifier K+ current: Differential sensitivity to block by class III antiarrhythmic agents
    • Sanguinetti MC, Jurkiewicz NK. Two components of cardiac delayed rectifier K+ current: differential sensitivity to block by class III antiarrhythmic agents. J Gen Physiol. 1990;96:195-215.
    • (1990) J Gen Physiol. , vol.96 , pp. 195-215
    • Sanguinetti, M.C.1    Jurkiewicz, N.K.2
  • 10
    • 0029024749 scopus 로고
    • Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type: Theoretical formulation and their role in repolarization
    • Zeng J, Laurita KR, Rosenbaum DS, Rudy Y. Two components of the delayed rectifier K+ current in ventricular myocytes of the guinea pig type: theoretical formulation and their role in repolarization. Circ Res. 1995;77:140-152.
    • (1995) Circ Res. , vol.77 , pp. 140-152
    • Zeng, J.1    Laurita, K.R.2    Rosenbaum, D.S.3    Rudy, Y.4
  • 12
    • 0031936234 scopus 로고    scopus 로고
    • Mutation of the gene for IsK associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome
    • Duggal P, Vesely MR, Wattanasirichaigoon D, Villafane J, Kaushik V, Beggs AH. Mutation of the gene for IsK associated with both Jervell and Lange-Nielsen and Romano-Ward forms of long-QT syndrome. Circulation. 1998;97:142-146.
    • (1998) Circulation , vol.97 , pp. 142-146
    • Duggal, P.1    Vesely, M.R.2    Wattanasirichaigoon, D.3    Villafane, J.4    Kaushik, V.5    Beggs, A.H.6
  • 13
    • 0028233422 scopus 로고
    • A dynamic model of the cardiac ventricular action potential, I: Simulations of ionic currents and concentration changes
    • Luo CH, Rudy Y. A dynamic model of the cardiac ventricular action potential, I: simulations of ionic currents and concentration changes. Circ Res. 1994;74:1071-1096.
    • (1994) Circ Res. , vol.74 , pp. 1071-1096
    • Luo, C.H.1    Rudy, Y.2
  • 14
    • 0028365308 scopus 로고
    • A dynamic model of the cardiac ventricular action potential. II: Afterdepolarizations, triggered activity, and potentiation
    • Luo CH, Rudy Y. A dynamic model of the cardiac ventricular action potential. II: afterdepolarizations, triggered activity, and potentiation. Circ Res. 1994;74:1097-1113.
    • (1994) Circ Res. , vol.74 , pp. 1097-1113
    • Luo, C.H.1    Rudy, Y.2
  • 15
    • 0025210005 scopus 로고
    • Calcium-sensitive delayed rectifier potassium current in guinea pig ventricular cells
    • Tohse N. Calcium-sensitive delayed rectifier potassium current in guinea pig ventricular cells. Am J Physiol. 1990;258:H1200-H1207.
    • (1990) Am J Physiol. , vol.258
    • Tohse, N.1
  • 16
    • 0028176733 scopus 로고
    • 2+-dependent enhancement of delayed rectifier K+ current in isolated membrane patches of guinea pig ventricular myocytes
    • 2+-dependent enhancement of delayed rectifier K+ current in isolated membrane patches of guinea pig ventricular myocytes. Circ Res. 1994;74:96-104.
    • (1994) Circ Res. , vol.74 , pp. 96-104
    • Nitta, J.1    Furukawa, T.2    Marumo, F.3    Sawanobori, T.4    Hiraoka, M.5
  • 17
    • 0030665763 scopus 로고    scopus 로고
    • Ionic mechanisms of propagation in cardiac tissue: Roles of the sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling
    • Shaw RM, Rudy Y. Ionic mechanisms of propagation in cardiac tissue: roles of the sodium and L-type calcium currents during reduced excitability and decreased gap junction coupling. Circ Res. 1997;81:727-741.
    • (1997) Circ Res. , vol.81 , pp. 727-741
    • Shaw, R.M.1    Rudy, Y.2
  • 18
    • 0026634674 scopus 로고
    • Gap junctional conductance in ventricular myocyte pairs isolated from postischemic rabbit myocardium
    • Kieval RS, Spear JF, Moore EN. Gap junctional conductance in ventricular myocyte pairs isolated from postischemic rabbit myocardium. Circ Res. 1992;71:127-136.
    • (1992) Circ Res. , vol.71 , pp. 127-136
    • Kieval, R.S.1    Spear, J.F.2    Moore, E.N.3
  • 19
    • 0027186122 scopus 로고
    • Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent: Specific block of rapidly activating delayed rectifier K+ current by dofetilide
    • Jurkiewicz NK, Sanguinetti MC. Rate-dependent prolongation of cardiac action potentials by a methanesulfonanilide class III antiarrhythmic agent: specific block of rapidly activating delayed rectifier K+ current by dofetilide. Circ Res. 1993;72:75-83.
    • (1993) Circ Res. , vol.72 , pp. 75-83
    • Jurkiewicz, N.K.1    Sanguinetti, M.C.2
  • 20
    • 0020085857 scopus 로고
    • Increase in intracellular sodium ion activity during stimulation in mammalian cardiac muscle
    • Cohen CJ, Fozzard HA, Sheu SS. Increase in intracellular sodium ion activity during stimulation in mammalian cardiac muscle. Circ Res. 1982;50:651-662.
    • (1982) Circ Res. , vol.50 , pp. 651-662
    • Cohen, C.J.1    Fozzard, H.A.2    Sheu, S.S.3
  • 21
    • 0028987152 scopus 로고
    • The role of Na+-Ca+ exchanger in the rate dependent increase in contraction in guinea-pig ventricular myocytes
    • Harrison SM, Boyett MR. The role of Na+-Ca+ exchanger in the rate dependent increase in contraction in guinea-pig ventricular myocytes. J Physiol. 1995;482:555-566.
    • (1995) J Physiol. , vol.482 , pp. 555-566
    • Harrison, S.M.1    Boyett, M.R.2
  • 22
    • 0029844535 scopus 로고    scopus 로고
    • Regional differences in electrophysiologic properties of epicardium, midmyocardium and endocardium: In vitro and in vivo correlations
    • Anyukhovsky EP, Sosunov EA, Rosen MR. Regional differences in electrophysiologic properties of epicardium, midmyocardium and endocardium: in vitro and in vivo correlations. Circulation. 1996;94: 1981-1988.
    • (1996) Circulation , vol.94 , pp. 1981-1988
    • Anyukhovsky, E.P.1    Sosunov, E.A.2    Rosen, M.R.3
  • 23
    • 0029835964 scopus 로고    scopus 로고
    • The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome: Tridimensional mapping of activation and recovery patterns
    • El-Sherif N, Caref EB, Yin H, Restivo M. The electrophysiological mechanism of ventricular arrhythmias in the long QT syndrome: tridimensional mapping of activation and recovery patterns. Circ Res. 1996; 79:474-492.
    • (1996) Circ Res. , vol.79 , pp. 474-492
    • El-Sherif, N.1    Caref, E.B.2    Yin, H.3    Restivo, M.4
  • 24
    • 0031919220 scopus 로고    scopus 로고
    • Hypoxia and hypothermia enhance spatial heterogeneities of repolarization in guinea pig hearts: Analysis of spatial autocorrelation of optically recorded action potential durations
    • Salama G, Kanai AJ, Huang D, Efimov IR, Girouard SD, Rosenbaum DS. Hypoxia and hypothermia enhance spatial heterogeneities of repolarization in guinea pig hearts: analysis of spatial autocorrelation of optically recorded action potential durations. J Cardiovasc Electrophysiol. 1998; 9:164-183.
    • (1998) J Cardiovasc Electrophysiol. , vol.9 , pp. 164-183
    • Salama, G.1    Kanai, A.J.2    Huang, D.3    Efimov, I.R.4    Girouard, S.D.5    Rosenbaum, D.S.6
  • 25
    • 0030819433 scopus 로고    scopus 로고
    • Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de pointes in LQT2 and LQT3 models of the long QT syndrome
    • Shimizu W, Antzelevitch C. Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de pointes in LQT2 and LQT3 models of the long QT syndrome. Circulation. 1997;96:2038-2047.
    • (1997) Circulation , vol.96 , pp. 2038-2047
    • Shimizu, W.1    Antzelevitch, C.2
  • 26
    • 0024359502 scopus 로고
    • Electrophysiologic substrate of torsade de pointes: Dispersion of repolarization or early afterdepolarizations
    • Surawicz B. Electrophysiologic substrate of torsade de pointes: dispersion of repolarization or early afterdepolarizations. J Am Coll Cardiol. 1989; 14:172-184.
    • (1989) J Am Coll Cardiol. , vol.14 , pp. 172-184
    • Surawicz, B.1
  • 27
    • 0029020834 scopus 로고
    • Reentry: Insights from theoretical simulations in a fixed pathway
    • Rudy Y. Reentry: insights from theoretical simulations in a fixed pathway. J Cardiovasc Electrophysiol. 1995;6:294-312.
    • (1995) J Cardiovasc Electrophysiol. , vol.6 , pp. 294-312
    • Rudy, Y.1
  • 28
    • 0024556795 scopus 로고
    • Early afterdepolarizations: Mechanism of induction and block: A role for L-type Ca2+ current
    • January CT, Riddle JM. Early afterdepolarizations: mechanism of induction and block: a role for L-type Ca2+ current. Circ Res. 1989;64: 977-990.
    • (1989) Circ Res. , vol.64 , pp. 977-990
    • January, C.T.1    Riddle, J.M.2
  • 29
    • 0029005888 scopus 로고
    • The control of calcium release in the heart muscle
    • Cannell MB, Cheng H, Lederer WJ. The control of calcium release in the heart muscle. Science. 1995;268:1045-1049.
    • (1995) Science , vol.268 , pp. 1045-1049
    • Cannell, M.B.1    Cheng, H.2    Lederer, W.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.