A model of the interaction between N-type and C-type inactivation in Kv1.4 channels

Biophysical Journal

Volumn 100, Issue 1, 2011, Pages 11-21

  Bett, Glenna C L ^a,b   Dinga Madou, Isidore ^b   Zhou, Qinlian ^b   Bondarenko, Vladimir E ^b   Rasmusson, Randall L ^b  

^a UNIVERSITY AT BUFFALO   (United States)

^b UNIVERSITY AT BUFFALO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 78651226179     PISSN: 00063495     EISSN: 15420086     Source Type: Journal    
DOI: 10.1016/j.bpj.2010.11.011     Document Type: Article

References (56)

1. + current in renal vascular smooth muscle. Pflugers Arch. 445:697-704.
2. Trimmer, J. S., and K. J. Rhodes. 2004. Localization of voltage-gated ion channels in mammalian brain. Annu. Rev. Physiol. 66:477-519.
3. Veh, R. W., R. Lichtinghagen, ., O. Pongs. 1995. Immunohistochemical localization of five members of the Kv1 channel subunits: Contrasting subcellular locations and neuron-specific co-localizations in rat brain. Eur. J. Neurosci. 7:2189-2205.
4. + channel proteins in rat central neurons. Neuron. 9:271-284.
5. Barry, D. M., and J. M. Nerbonne. 1996. Myocardial potassium channels: Electrophysiological and molecular diversity. Annu. Rev. Physiol. 58:363-394.
6. Dixon, J. E., and D. McKinnon. 1994. Quantitative analysis of potassium channel mRNA expression in atrial and ventricular muscle of rats. Circ. Res. 75:252-260.
7. + channel cDNAs from human ventricle. FASEB J. 5:331-337.
8. + channel gene expression in diabetic rat ventricle: Isoform switching between Kv4.2 and Kv1.4. Am. J. Physiol. (Heart). 281:H1800-H1807.
9. + channels in rat heart with right ventricular hypertrophy. Am. J. Physiol. 277:H1725-H1731.
10. 2+]i in rat ventricular myocytes following myocardial infarction. J. Physiol. 517:229-245.
11. Hoshi, T., W. N. Zagotta, and R. W. Aldrich. 1990. Biophysical and molecular mechanisms of Shaker potassium channel inactivation. Science. 250:533-538.
12. Zagotta,W. N., T. Hoshi, and R.W. Aldrich. 1990. Restoration of inactivation in mutants of Shaker potassium channels by a peptide derived from ShB. Science. 250:568-571.
13. + channel. Nature. 353:86-90.
14. + channels. Circ. Res. 82:739-750.
15. + channels expressed in Xenopus oocytes. J. Physiol. 549:683-695.
16. +]: A tale of two inactivation mechanisms. Neuron. 15:951-960.
17. + channel (Kv1.4) expressed in Xenopus oocytes. J. Physiol. 489:709-721.
18. + channels: Effects of alterations in the carboxyterminal region. Neuron. 7:547-556.
19. + channel b-subunit increases the rate of C-type inactivation from the cytoplasmic side of the channel. Proc. Natl. Acad. Sci. USA. 93:15119-15123.
20. Lopez-Barneo, J., T. Hoshi,., R.W. Aldrich. 1993. Effects of external cations and mutations in the pore region on C-type inactivation of Shaker potassium channels. Receptors Channels. 1:61-71.
21. Bett, G. C., and R. L. Rasmusson. 2003. Functionally-distinct protonbinding in HERG suggests the presence of two binding sites. Cell Biochem. Biophys. 39:183-193.
22. Comer, M. B., D. L. Campbell, ., H. C. Strauss. 1994. Cloning and characterization of an Ito-like potassium channel from ferret ventricle. Am. J. Physiol. 267:H1383-H1395.
23. Hodgkin, A. L., and A. F. Huxley. 1952. A quantitative description of membrane current and its application to conduction and excitation in nerve. J. Physiol. 117:500-544.
24. + channel. J. Gen. Physiol. 112: 377-389.
25. + channels. Physiol. Rev. 71:1047-1080.
26. + channels altered by presence of b-subunit. Nature. 369:289-294.
27. Morales, M. J., R. C. Castellino, ., H. C. Strauss. 1995. A novel b-subunit increases rate of inactivation of specific voltage-gated potassium channel a-subunits. J. Biol. Chem. 270:6272-6277.
28. + channel b-subunit (hKv b 1.3) is produced via alternative mRNA splicing. J. Biol. Chem. 270:28531-28534.
29. Wang, S., M. J. Morales, ., R. L. Rasmusson. 2003. Kv1.4 channel block by quinidine: Evidence for a drug-induced allosteric effect. J. Physiol. 546:387-401.
30. + channels: Lipophilic interactions at the intracellular mouth of the pore. J. Physiol. 556:109-120.
31. + channel. J. Membr. Biol. 157:215-230.
32. Zhou, M., J. H. Morais-Cabral, ., R. MacKinnon. 2001. Potassium channel receptor site for the inactivation gate and quaternary amine inhibitors. Nature. 411:657-661.
33. + channels. Proc. Natl. Acad. Sci. USA. 88:5092-5095.
34. Lipkind, G. M., D. A. Hanck, and H. A. Fozzard. 1995. A structural motif for the voltage-gated potassium channel pore. Proc. Natl. Acad. Sci. USA. 92:9215-9219.
35. Busch, A. E., R. S. Hurst, ., M. P. Kavanaugh. 1991. Current inactivation involves a histidine residue in the pore of the rat lymphocyte potassium channel RGK5. Biochem. Biophys. Res. Commun. 179:1384-1390.
36. + channels. Circ. Res. 82: 386-395.
37. +: Evidence for transmembrane communication. Am. J. Physiol. (Heart). 284:H71-H80.
38. Qu, Y., J. C. Rogers, ., W. A. Catterall. 1999. Functional roles of the extracellular segments of the sodium channel a-subunit in voltagedependent gating and modulation by b1 subunits. J. Biol. Chem. 274:32647-32654.
39. Zhang, J. F., P. T. Ellinor, ., R. W. Tsien. 1994. Molecular determinants of voltage-dependent inactivation in calcium channels. Nature. 372:97-100.
40. + channels is produced by a structural rearrangement of the outer vestibule. Biophys. J. 76:1335-1345.
41. Marom, S., and I. B. Levitan. 1994. State-dependent inactivation of the Kv3 potassium channel. Biophys. J. 67:579-589.
42. Wang, S., V. E. Bondarenko, ., H. C. Strauss. 2005. Time- and voltage-dependent components of Kv4.3 inactivation. Biophys. J. 89: 3026-3041.
43. Dougherty, K., J. A. Santiago-Castillo, and M. Covarrubias. 2008. Gating charge immobilization in Kv4.2 channels: The basis of closedstate inactivation. J. Gen. Physiol. 131:257-273.
44. Klemic, K. G., G. E. Kirsch, and S.W. Jones. 2001. U-type inactivation of Kv3.1 and Shaker potassium channels. Biophys. J. 81:814-826.
45. Klemic, K. G., C. C. Shieh,., S.W. Jones. 1998. Inactivation of Kv2.1 potassium channels. Biophys. J. 74:1779-1789.
46. Kramer, J.W., M. A. Post,., G. E. Kirsch. 1998. Modulation of potassium channel gating by coexpression of Kv2.1 with regulatory Kv5.1 or Kv6.1 a-subunits. Am. J. Physiol. 274:C1501-C1510.
47. Kerschensteiner, D., and M. Stocker. 1999. Heteromeric assembly of Kv2.1 with Kv9.3: Effect on the state dependence of inactivation. Biophys. J. 77:248-257.
48. + channeldrug interactions by ancillary subunits. J. Physiol. 586:929-950.
49. Hoshi, T., W. N. Zagotta, and R. W. Aldrich. 1994. Shaker potassium channel gating. I: Transitions near the open state. J. Gen. Physiol. 103:249-278.
50. Castellino, R. C., M. J. Morales,., R. L. Rasmusson. 1995. Time- and voltage-dependent modulation of a Kv1.4 channel by a b-subunit (Kv b 3) cloned from ferret ventricle. Am. J. Physiol. 269:H385-H391.
51. Bezanilla, F. 2005. Voltage-gated ion channels. IEEE Trans. Nanobioscience. 4:34-48.
52. Crouzy, S. C., and F. J. Sigworth. 1993. Fluctuations in ion channel gating currents. Analysis of nonstationary shot noise. Biophys. J. 64: 68-76.
53. Chapman, M. L., H. M. VanDongen, and A. M. VanDongen. 1997. Activation-dependent subconductance levels in the Drk1 K channel suggest a subunit basis for ion permeation and gating. Biophys. J. 72:708-719.
54. D'Adamo, M. C., Z. Liu, ., M. Pessia. 1998. Episodic ataxia type-1 mutations in the hKv1.1 cytoplasmic pore region alter the gating properties of the channel. EMBO J. 17:1200-1207.
55. + conductance. J. Physiol. 588:2691-2706.
56. Fedida, D., and J. C. Hesketh. 2001. Gating of voltage-dependent potassium channels. Prog. Biophys. Mol. Biol. 75:165-199.