Frequency-dependent effects of various IKr blockers on cardiac action potential duration in a human atrial model

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 293, Issue 1, 2007, Pages

  Tsujimae, Kenji ^a   Suzuki, Shingo ^a   Murakami, Shingo ^a   Kurachi, Yoshihisa ^a,b  

^a OSAKA UNIVERSITY   (Japan)

^b OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Atrial action potential; Computer simulation; Rapidly activating potassium current; Reverse frequency dependence; Slowly activating potassium current

Indexed keywords

DOFETILIDE; PIPERANOMETOZINE; POTASSIUM; QUINIDINE; VOLTAGE GATED POTASSIUM CHANNEL;

ARTICLE; CELL MEMBRANE DEPOLARIZATION; HEART ATRIUM CONTRACTILITY; HEART MUSCLE CONTRACTILE FORCE; HEART MUSCLE CONTRACTILITY; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; INOTROPISM; MATHEMATICAL MODEL; MUSCLE ACTION POTENTIAL; MUSCLE STRENGTH; POTASSIUM CURRENT; PRIORITY JOURNAL;

ACTION POTENTIALS; ATRIAL FUNCTION; COMPUTER SIMULATION; HEART CONDUCTION SYSTEM; HEART RATE; HUMANS; ION CHANNEL GATING; MODELS, CARDIOVASCULAR; POTASSIUM; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS;

EID: 34547125323     PISSN: 03636135     EISSN: 15221539     Source Type: Journal    
DOI: 10.1152/ajpheart.01083.2006     Document Type: Article

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