Acute effects of sex steroid hormones on susceptibility to cardiac arrhythmias: A simulation study

PLoS Computational Biology

Volumn 6, Issue 1, 2010, Pages

  Yang, Pei Chi ^a   Kurokawa, Junko ^b   Furukawa, Tetsushi ^b   Clancy, Colleen E ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

DISEASES; ELECTROPHYSIOLOGY; ENDOCRINOLOGY; HEART; PHYSIOLOGICAL MODELS; STEROID HORMONES;

ACTION POTENTIAL DURATIONS; CARDIAC ARRHYTHMIA; CARDIAC ION CHANNELS; COMPUTATIONAL MODELLING; MODELING APPROACH; OESTROGENS; PROGESTERON; SEX STEROID HORMONES; SIMULATION STUDIES; TESTOSTERONE;

COMPUTATION THEORY;

ESTRADIOL; ION CHANNEL; PROGESTERONE; SEX HORMONE; TESTOSTERONE; 1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; ANTIARRHYTHMIC AGENT; ESTROGEN; PIPERIDINE DERIVATIVE; POTASSIUM CHANNEL; PYRIDINE DERIVATIVE;

ACTION POTENTIAL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; DRUG INDUCED DISEASE; ESTRADIOL BLOOD LEVEL; FEMALE; HEART ARRHYTHMIA; HEART MUSCLE CELL; HEART VENTRICLE; MALE; MENSTRUAL CYCLE; NONHUMAN; PHYSIOLOGY; PROGESTERONE BLOOD LEVEL; QT INTERVAL; QT PROLONGATION; SIMULATION; TESTOSTERONE BLOOD LEVEL; TORSADE DES POINTES; ANIMAL; CELL CULTURE; COMPUTER SIMULATION; DRUG EFFECT; ELECTROCARDIOGRAPHY; GUINEA PIG; METABOLISM; PROBABILITY;

ACTION POTENTIALS; ANIMALS; ANTI-ARRHYTHMIA AGENTS; ARRHYTHMIAS, CARDIAC; CELLS, CULTURED; COMPUTER SIMULATION; DISEASE SUSCEPTIBILITY; ELECTROCARDIOGRAPHY; ESTROGENS; FEMALE; GONADAL STEROID HORMONES; GUINEA PIGS; MALE; MARKOV CHAINS; MENSTRUAL CYCLE; MYOCYTES, CARDIAC; PIPERIDINES; POTASSIUM CHANNELS; PROGESTERONE; PYRIDINES; TESTOSTERONE;

EID: 76749160779     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1000658     Document Type: Article

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