A computational model of Purkinje fibre single cell electrophysiology: Implications for the long QT syndrome

Journal of Physiology

Volumn 588, Issue 14, 2010, Pages 2643-2655

  Sampson, K J ^a   Iyer, V ^a   Marks, A R ^a   Kass, R S ^a  

^a New York Presbyterian Columbia University Medical Center   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC NUCLEOTIDE GATED CHANNEL; ION CHANNEL; POTASSIUM CHANNEL; AGENTS AFFECTING WATER, MOLECULE OR ION TRANSPORT; CALCIUM CHANNEL; DELAYED RECTIFIER POTASSIUM CHANNEL; SODIUM CHANNEL;

ACTION POTENTIAL; ARRHYTHMOGENESIS; ARTICLE; BIOPHYSICS; CALCIUM CELL LEVEL; CALCIUM CURRENT; CELL FUNCTION; CELL ISOLATION; COMPUTER MODEL; CONTROLLED STUDY; DISEASE SEVERITY; ELECTRIC POTENTIAL; ELECTROPHYSIOLOGY; EMBRYO; HEART AUTOMATICITY; HEART MUSCLE CELL; HEART VENTRICLE; HUMAN; HUMAN CELL; HYPERPOLARIZATION; IN VITRO STUDY; LONG QT SYNDROME; MATHEMATICAL MODEL; MEMBRANE CURRENT; PREDICTION; PRIORITY JOURNAL; PURKINJE FIBER; SIMULATION; SODIUM CURRENT; BIOLOGICAL MODEL; COMPUTER SIMULATION; DRUG EFFECTS; HEART ARRHYTHMIA; PATHOPHYSIOLOGY; PHYSIOLOGY; HEART MUSCLE FIBER MEMBRANE STEADY POTENTIAL; POTASSIUM CURRENT; PURKINJE FIBER MEMBRANE POTENTIAL; VALIDATION STUDY;

ACTION POTENTIALS; ARRHYTHMIAS, CARDIAC; COMPUTER SIMULATION; HUMANS; ION CHANNELS; LONG QT SYNDROME; MEMBRANE TRANSPORT MODULATORS; MODELS, NEUROLOGICAL; MYOCYTES, CARDIAC; PURKINJE FIBERS;

EID: 77954742469     PISSN: 00223751     EISSN: 14697793     Source Type: Journal    
DOI: 10.1113/jphysiol.2010.187328     Document Type: Article

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