Role of Tumor-Associated Macrophages (TAM) in Cancer Related Inflammation

Tumor Microenvironment

Volumn , Issue , 2010, Pages 77-98

  Sica, Antonio ^a,b   Porta, Chiara ^a,b  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

^b HUMANITAS CLINICAL AND RESEARCH CENTER   (Italy)

Author keywords

Changes in iron (Fe) metabolism M1 M2 macrophage polarization; M2 signature for cancer progression; Macrophages as key orchestrators of cancer related inflammation; Macrophages, of innate defense mechanisms promoting specific immunity, T cell recruitment and activation; Macrophages, released from bone marrow in blood stream as immature monocytes; Molecular basis of TAM mediated immunosuppression and T cell activation inhibition; Molecular determinants of TAM functions; Murine tumor models CSF 1 in TAM mediated angiogenesis; Polarized inflammation, and different roles in tumor progression; Role of tumor associated macrophages (TAM) in cancer related inflammation

Indexed keywords

EID: 80052393603     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1002/9780470669891.ch5     Document Type: Chapter

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