Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon-mediated immunity

Nature Immunology

Volumn 12, Issue 8, 2011, Pages 733-741

  Tun Kyi, Adrian ^a   Finn, Greg ^a   Greenwood, Alex ^b   Nowak, Michael ^a   Lee, Tae Ho ^a   Asara, John M ^a   Tsokos, George C ^a   Fitzgerald, Kate ^c   Israel, Elliot ^d   Li, Xiaoxia ^e   Exley, Mark ^a   Nicholson, Linda K ^b   Lu, Kun Ping ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b Department of Obstetrics Gynecology   (United States)

^c UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

INTERFERON; INTERFERON REGULATORY FACTOR 7; INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE 1; PEPTIDYLPROLYL ISOMERASE PIN1; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 9;

ANIMAL CELL; ANIMAL EXPERIMENT; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME RELEASE; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REVIEW;

ADAPTIVE IMMUNITY; ANIMALS; DENDRITIC CELLS; IMMUNITY, INNATE; IMMUNOBLOTTING; INTERFERON REGULATORY FACTOR-1; INTERFERON-BETA; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PEPTIDYLPROLYL ISOMERASE; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTORS;

EID: 80052026067     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.2069     Document Type: Review

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