Cu(II) mediates kinetically distinct, non-amyloidogenic aggregation of amyloid-β peptides

Journal of Biological Chemistry

Volumn 286, Issue 30, 2011, Pages 26952-26963

  Pedersen, Jeppe T ^a   Østergaard, Jesper ^a   Rozlosnik, Noemi ^b   Gammelgaard, Bente ^a   Heegaard, Niels H H ^c  

^a UNIVERSITY OF COPENHAGEN   (Denmark)

^b TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^c STATENS SERUM INSTITUT   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

AGGREGATE MORPHOLOGY; AGGREGATION KINETICS; AGGREGATION MECHANISM; ALZHEIMER DISEASE; END POINTS; EXTRACELLULAR; KEY REACTIONS; MECHANISTIC MODELS; MICROELECTROPHORETIC; MORPHOLOGICAL CHANGES; QUANTITATIVE INFLUENCE; SPHERICAL AGGREGATES;

AGGREGATES; EXPERIMENTS; GLYCOPROTEINS; MORPHOLOGY; NEURODEGENERATIVE DISEASES; PEPTIDES; STOICHIOMETRY;

KINETICS;

AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-16]; AMYLOID BETA PROTEIN[1-28]; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; CUPRIC ION; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ARTICLE; CHEMICAL REACTION KINETICS; CONCENTRATION RESPONSE; CONTROLLED STUDY; EXTRACELLULAR SPACE; IN VITRO STUDY; METAL BINDING; MOLECULAR MODEL; PEPTIDE ANALYSIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN STABILITY; QUALITATIVE RESEARCH; QUANTITATIVE STUDY; RESIDUE ANALYSIS; ULTRASTRUCTURE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; CATIONS, DIVALENT; COPPER; HUMANS; MODELS, CHEMICAL; PEPTIDES; PROTEIN BINDING;

EID: 79960694577     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M111.220863     Document Type: Article

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