Alzheimer's β-peptide oligomer formation at physiologic concentrations

Analytical Biochemistry

Volumn 335, Issue 1, 2004, Pages 81-90

  LeVine III, Harry ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Amyloid; Antibodies; ELISA; Gel permeation chromatography; Kinetics; Thermodynamics

Indexed keywords

ANTIBODIES; CHEMICAL DETECTION; CRITICAL MICELLE CONCENTRATION; DIMETHYL SULFOXIDE; DYES; ENZYME KINETICS; EPITOPES; GEL PERMEATION CHROMATOGRAPHY; IONIC STRENGTH; MICELLES; MOLECULAR WEIGHT; PEPTIDES; PHYSIOLOGY; POTASSIUM COMPOUNDS; SOAPS (DETERGENTS); SODIUM CHLORIDE; TEMPERATURE DISTRIBUTION; THERMODYNAMICS;

AMYLOID; ELISA; HIGH MOLECULAR WEIGHT; IMMUNOSORBANT ASSAY; LINEAR TEMPERATURE DEPENDENCE; LOW-MOLECULAR-WEIGHT SPECIES; NANOMOLAR CONCENTRATION; OLIGOMERIC STRUCTURE;

OLIGOMERS;

AMYLOID BETA PROTEIN[1-42]; OLIGOMER;

AMINO ACID SEQUENCE; ANTIBODY DETECTION; ARTICLE; DILUTION; ENZYME LINKED IMMUNOSORBENT ASSAY; GEL PERMEATION CHROMATOGRAPHY; IMMUNOREACTIVITY; IONIC STRENGTH; KINETICS; MOLECULAR RECOGNITION; MOLECULAR WEIGHT; OLIGOMERIZATION; PRIORITY JOURNAL; TEMPERATURE MEASUREMENT;

EID: 7444247272     PISSN: 00032697     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ab.2004.08.014     Document Type: Article

References (54)

1. K. Senior Soluble amyloid oligomers: a common cause of neurodegeneration? Lancet Neurol. 2 2003 330
2. W.L. Klein, G.A. Krafft, and C.E. Finch Targeting small Abeta oligomers: the solution to an Alzheimer's disease conundrum? Trends Neurosci. 24 2001 219 224
3. C. Nilsberth, A. Westlind Danielsson, C.B. Eckman, M.M. Condron, K. Axelman, C. Forsell, C. Stenh, J. Luthman, D.B. Teplow, S.G. Younkin, J. Naslund, and L. Lannfelt The 'Arctic' APP mutation (E693G) causes Alzheimer's disease by enhanced Abeta protofibril formation Nat. Neurosci. 4 2001 887 893
4. M.J. Volles, and P.T. Lansbury Jr. Zeroing in on the pathogenic form of alpha-synuclein and its mechanism of neurotoxicity in parkinson's disease Biochemistry 42 2003 7871 7878
5. R. Kayed, E. Head, J.L. Thompson, T.M. McIntire, S.C. Milton, C.W. Cotman, and C.G. Glabe Common structure of soluble amyloid oligomers implies common mechanism of pathogenesis Science 300 2003 486 489
6. J. Naslund, V. Haroutunian, R. Mohs, K.L. Davis, P. Davies, P. Greengard, and J.D. Buxbaum Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline J. Am. Med. Assoc. 283 2000 1571 1577
7. P. Giannakopoulos, F.R. Herrmann, T. Bussiere, C. Bouras, E. Kovari, D.P. Perl, J.H. Morrison, G. Gold, and P.R. Hof Tangle and neuron numbers, but not amyloid load, predict cognitive status in Alzheimer's disease Neurology 60 2003 1495 1500
8. D.A. Bennett, J.A. Schneider, R.S. Wilson, J.L. Bienias, and S.E. Arnold Neurofibrillary tangles mediate the association of amyloid load with clinical Alzheimer disease and level of cognitive function Arch. Neurol. 61 2004 378 384
9. G.T. Bartoo, D. Nochlin, D. Chang, Y. Kim, and S.M. Sumi The mean Abeta load in the hippocampus correlates with duration and severity of dementia in subgroups of Alzheimer disease J. Neuropathol. Exp. Neurol. 56 1997 531 540
10. L.F. Lue, Y.M. Kuo, A.E. Roher, L. Brachova, Y. Shen, L. Sue, T. Beach, J.H. Kurth, R.E. Rydel, and J. Rogers Soluble amyloid beta peptide concentration as a predictor of synaptic change in Alzheimer's disease Am. J. Pathol. 155 1999 853 862
11. C.A. McLean, R.A. Cherny, F.W. Fraser, S.J. Fuller, M.J. Smith, K. Beyreuther, A.I. Bush, and C.L. Masters Soluble pool of Abeta amyloid as a determinant of severity of neurodegeneration in Alzheimer's disease Ann. Neurol. 46 1999 860 866
12. J. Wang, D.W. Dickson, J.Q. Trojanowski, and V.M. Lee The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging Exp. Neurol. 158 1999 328 337
13. K.N. Dahlgren, A.M. Manelli, W.B. Stine Jr., L.K. Baker, G.A. Krafft, and M.J. LaDu Oligomeric and fibrillar species of amyloid-beta peptides differentially affect neuronal viability J. Biol. Chem. 277 2002 32046 32053
14. D.M. Hartley, D.M. Walsh, C.P. Ye, T. Diehl, S. Vasquez, P.M. Vassilev, D.B. Teplow, and D.J. Selkoe Protofibrillar intermediates of amyloid beta-protein induce acute electrophysiological changes and progressive neurotoxicity in cortical neurons J. Neurosci. 19 1999 8876 8884
15. Y.M. Kuo, M.R. Emmerling, C. Vigo-Pelfrey, T.C. Kasunic, J.B. Kirkpatrick, G.H. Murdoch, M.J. Ball, and A.E. Roher Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains J. Biol. Chem. 271 1996 4077 4081
16. Y. Gong, L. Chang, K.L. Viola, P.N. Lacor, M.P. Lambert, C.E. Finch, G.A. Krafft, and W.L. Klein Alzheimer's disease-affected brain: presence of oligomeric Abeta ligands (ADDLs) suggests a molecular basis for reversible memory loss Proc. Natl. Acad. Sci. USA 100 2003 10417 10422
17. B. O'Nuallain, and R. Wetzel Conformational Abs recognizing a generic amyloid fibril epitope Proc. Natl. Acad. Sci. USA 99 2002 1485 1490
18. D.L. Miller, J.R. Currie, P.D. Mehta, A. Potempska, Y.W. Hwang, and J. Wegiel Humoral immune response to fibrillar beta-amyloid peptide Biochemistry 42 2003 11682 11692
19. B.A. Chromy, R.J. Nowak, M.P. Lambert, K.L. Viola, L. Chang, P.T. Velasco, B.W. Jones, S.J. Fernandez, P.N. Lacor, P. Horowitz, C.E. Finch, G.A. Krafft, and W.L. Klein Self-assembly of Abeta(1-42) into globular neurotoxins Biochemistry 42 2003 12749 12760
20. W.E. Klunk, R.F. Jacob, and R.P. Mason Quantifying amyloid by congo red spectral shift assay Methods Enzymol. 309 1999 285 305
21. H. LeVine III Quantification of beta-sheet amyloid fibril structures with thioflavin T Methods Enzymol. 309 1999 274 284
22. H. LeVine III Soluble multimeric Alzheimer beta(1-40) pre-amyloid complexes in dilute solution Neurobiol. Aging 16 1995 755 764
23. G. Bitan, M.D. Kirkitadze, A. Lomakin, S.S. Vollers, G.B. Benedek, and D.B. Teplow Amyloid beta-protein (Abeta) assembly: Abeta 40 and Abeta 42 oligomerize through distinct pathways Proc. Natl. Acad. Sci. USA 100 2003 330 335
24. S.M. Dudek, and G.V. Johnson Transglutaminase facilitates the formation of polymers of the beta-amyloid peptide Brain Res. 651 1994 129 133
25. O.M. El Agnaf, D.S. Mahil, B.P. Patel, and B.M. Austen Oligomerization and toxicity of beta-amyloid-42 implicated in Alzheimer's disease Biochem. Biophys. Res. Commun. 273 2000 1003 1007
26. D. Howlett, P. Cutler, S. Heales, and P. Camilleri Hemin and related porphyrins inhibit beta-amyloid aggregation FEBS Lett. 417 1997 249 251
27. R.V. Ward, K.H. Jennings, R. Jepras, W. Neville, D.E. Owen, J. Hawkins, G. Christie, J.B. Davis, A. George, E.H. Karran, and D.R. Howlett Fractionation and characterization of oligomeric, protofibrillar and fibrillar forms of beta-amyloid peptide Biochem. J. 15 2000 1137 1144
28. K. Hasegawa, K. Ono, M. Yamada, and H. Naiki Kinetic modeling and determination of reaction constants of Alzheimer's beta-amyloid fibril extension and dissociation using surface plasmon resonance Biochemistry 41 2002 13489 13498
29. A. Frey, B. Meckelein, D. Externest, and M.A. Schmidt A stable and highly sensitive 3,3′,5,5′-tetramethylbenzidine-based substrate reagent for enzyme-linked immunosorbent assays J. Immunol. Methods 233 2000 47 56
30. G. Bitan, A. Lomakin, and D.B. Teplow Amyloid beta-protein oligomerization: prenucleation interactions revealed by photo-induced cross-linking of unmodified proteins J. Biol. Chem. 276 2001 35176 35184
31. P.D. Mehta, T. Pirttila, S.P. Mehta, E.A. Sersen, P.S. Aisen, and H.M. Wisniewski Plasma and cerebrospinal fluid levels of amyloid beta proteins 1-40 and 1-42 in Alzheimer disease Arch. Neurol. 57 2000 100 105
32. Y. Kusumoto, A. Lomakin, D.B. Teplow, and G.B. Benedek Temperature dependence of amyloid beta-protein fibrillization Proc. Natl. Acad. Sci. USA 95 1998 12277 12282
33. W.P. Esler, A.M. Felix, E.R. Stimson, M.J. Lachenmann, J.R. Ghilardi, Y.A. Lu, H.V. Vinters, P.W. Mantyh, J.P. Lee, and J.E. Maggio Activation barriers to structural transition determine deposition rates of Alzheimer's disease a beta amyloid J. Struct. Biol. 130 2000 174 183
34. A. Lomakin, D.S. Chung, G.B. Benedek, D.A. Kirschner, and D.B. Teplow On the nucleation and growth of amyloid beta-protein fibrils: detection of nuclei and quantitation of rate constants Proc. Natl. Acad. Sci. USA 93 1996 1125 1129
35. J.T. Jarrett, E.P. Berger, and P.T. Lansbury Jr. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease Biochemistry 32 1993 4693 4697
36. M.F. Bishop, and F.A. Ferrone Kinetics of nucleation-controlled polymerization. A perturbation treatment for use with a secondary pathway Biophys. J. 46 1984 631 644
37. A.J. Modler, K. Gast, G. Lutsch, and G. Damaschun Assembly of amyloid protofibrils via critical oligomers-a novel pathway of amyloid formation J. Mol. Biol. 325 2003 135 148
38. B.P. Tseng, W.P. Esler, C.B. Clish, E.R. Stimson, J.R. Ghilardi, H.V. Vinters, P.W. Mantyh, J.P. Lee, and J.E. Maggio Deposition of monomeric, not oligomeric, Abeta mediates growth of Alzheimer's disease amyloid plaques in human brain preparations Biochemistry 38 1999 10424 10431
39. M.D. Kirkitadze, M.M. Condron, and D.B. Teplow Identification and characterization of key kinetic intermediates in amyloid beta-protein fibrillogenesis J. Mol. Biol. 312 2001 1103 1119
40. N. Bark, L. Tjernberg, R. Rigler, L. Terenius, Fluorescence Burst Analysis of Cerebrospinal Fluid as a Diagnostic Tool for Alzheimer's Disease, 8th International Conference on Alzheimers Disease and Related Disorders (2002) (Abstr 1382)
41. M. Pitschke, R. Prior, M. Haupt, and D. Riesner Detection of single amyloid beta-protein aggregates in the cerebrospinal fluid of Alzheimer's patients by fluorescence correlation spectroscopy Nat. Med. 4 1998 832 834 (see comments)
42. D.M. Walsh, D.M. Hartley, Y. Kusomoto, Y. Fezoui, M.M. Condron, A. Lomakin, G.B. Benedek, D.J. Selkoe, and D.B. Teplow Amyloid β-protein fibrillogenesis. Structure and biological activity of protofibrillar intermediates J. Biol. Chem. 274 1999 25949 25952
43. D.M. Walsh, I. Klyubin, J.V. Fadeeva, W.K. Cullen, R. Anwyl, M.S. Wolfe, M.J. Rowan, and D.J. Selkoe Naturally secreted oligomers of amyloid beta protein potently inhibit hippocampal long-term potentiation in vivo Nature 416 2002 535 539
44. D.M. Walsh, A. Lomakin, G.B. Benedek, M.M. Condron, and D.B. Teplow Amyloid beta-protein fibrillogenesis. Detection of a protofibrillar intermediate J. Biol. Chem. 272 1997 22364 22372
45. W. Garzon-Rodriguez, M. Sepulveda-Becerra, S. Milton, and C.G. Glabe Soluble amyloid Abeta-(1-40) exists as a stable dimer at low concentrations J. Biol. Chem. 272 1997 21037 21044
46. H.A. Lashuel, D.M. Hartley, B.M. Petre, J.S. Wall, M.N. Simon, T. Walz, and P.T. Lansbury Jr. Mixtures of wild-type and a pathogenic (E22G) form of Abeta40 in vitro accumulate protofibrils, including amyloid pores J. Mol. Biol. 332 2003 795 808
47. D.A. Fancy, C. Denison, K. Kim, Y. Xie, T. Holdeman, F. Amini, and T. Kodadek Scope, limitations and mechanistic aspects of the photo-induced cross-linking of proteins by water-soluble metal complexes Chem. Biol. 7 2000 697 708
48. D.A. Fancy, and T. Kodadek Chemistry for the analysis of protein-protein interactions: rapid and efficient cross-linking triggered by long wavelength light Proc. Natl. Acad. Sci. USA 96 1999 6020 6024
49. P.J. Flory Principles of Polymer Chemistry 1953 Cornell University Press Ithaca
50. D. Zhao, and J.S. Moore Nucleation-elongation: a mechanism for cooperative supramolecular polymerization Org. Biomol. Chem. 1 2003 3471 3491
51. D. Zhao, and J.S. Moore Nucleation-elongation polymerization under imbalanced stoichiometry J. Am. Chem. Soc. 125 2003 16294 16299
52. P.D. Mehta, T. Pirttila, B.A. Patrick, M. Barshatzky, and S.P. Mehta Amyloid beta protein 1-40 and 1-42 levels in matched cerebrospinal fluid and plasma from patients with Alzheimer disease Neurosci. Lett. 304 2001 102 106
53. M.R. Emmerling, M.C. Morganti Kossmann, T. Kossmann, P.F. Stahel, M.D. Watson, L.M. Evans, P.D. Mehta, K. Spiegel, Y.M. Kuo, A.E. Roher, and C.A. Raby Traumatic brain injury elevates the Alzheimer's amyloid peptide Abeta 42 in human CSF. A possible role for nerve cell injury Ann. N. Y. Acad. Sci. 903 2000 118 122
54. R. Mayeux, L.S. Honig, M.X. Tang, J. Manly, Y. Stern, N. Schupf, and P.D. Mehta Plasma Abeta40 and Abeta42 and Alzheimer's disease: relation to age, mortality, and risk Neurology 61 2003 1185 1190