메뉴 건너뛰기




Volumn 43, Issue 3, 2011, Pages 183-200

Precursor lesions in pancreatic cancer: Morphological and molecular pathology

Author keywords

Cancer; Pancreas; Pathology; Precursor

Indexed keywords

ANIMAL; CARCINOMA IN SITU; COLLOID CARCINOMA; CYSTADENOCARCINOMA; DISEASE COURSE; DISEASE MODEL; GENETICS; HUMAN; MOLECULAR PATHOLOGY; MOUSE; MUTATION; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; PRECANCER; PROGNOSIS; REVIEW;

EID: 79960674148     PISSN: 00313025     EISSN: 14653931     Source Type: Journal    
DOI: 10.1097/PAT.0b013e3283445e3a     Document Type: Review
Times cited : (67)

References (174)
  • 2
    • 85031217314 scopus 로고    scopus 로고
    • Australian Institute for Health and Welfare (AIHW) Canberra: AIHW
    • Australian Institute for Health and Welfare (AIHW). Cancer in Australia: an Overview, 2008. Canberra: AIHW, 2008.
    • Cancer in Australia: An Overview, 2008 , vol.2008
  • 4
    • 0014374540 scopus 로고
    • A correlative study of proven carcinoma of the pancreas in 83 patients
    • Ansari A, Burch GE. A correlative study of proven carcinoma of the pancreas in 83 patients. Am J Gastroenterol 1968; 50: 456-75.
    • (1968) Am J Gastroenterol , vol.50 , pp. 456-475
    • Ansari, A.1    Burch, G.E.2
  • 5
    • 0018155602 scopus 로고
    • Pancreas cancer I: Duct adenocarcinoma. A clinico-pathologic study of 380 patients
    • Cubilla AL, Fitzgerald PJ. Pancreas Cancer I: Duct adenocarcinoma. A clinico-pathologic study of 380 patients. Pathol Annu 1978; 13: 241-89.
    • (1978) Pathol Annu , vol.13 , pp. 241-289
    • Cubilla, A.L.1    Fitzgerald, P.J.2
  • 6
    • 54249088477 scopus 로고    scopus 로고
    • Pancreatic stellate cells and pancreatic cancer cells: An unholy alliance
    • Vonlaufen A, Phillips PA, Xu Z, et al. Pancreatic stellate cells and pancreatic cancer cells: an unholy alliance. Cancer Res 2008; 68: 7707-10.
    • (2008) Cancer Res , vol.68 , pp. 7707-7710
    • Vonlaufen, A.1    Phillips, P.A.2    Xu, Z.3
  • 7
    • 0034219829 scopus 로고    scopus 로고
    • Quality of life and long-term survival after surgery for chronic pancreatitis
    • discussion 64-5
    • Sohn TA, Campbell KA, Pitt HA, et al. Quality of life and long-term survival after surgery for chronic pancreatitis. J Gastrointest Surg 2000; 4: 355-64; discussion 64-5.
    • (2000) J Gastrointest Surg , vol.4 , pp. 355-364
    • Sohn, T.A.1    Campbell, K.A.2    Pitt, H.A.3
  • 8
    • 0025236629 scopus 로고
    • Survival after pancreatoduodenectomy: 118 Consecutive resections without an operative mortality
    • Trede M, Schwall G, Saeger HD. Survival after pancreatoduodenectomy. 118 consecutive resections without an operative mortality. Ann Surg 1990; 211: 447-58. (Pubitemid 20138186)
    • (1990) Annals of Surgery , vol.211 , Issue.4 , pp. 447-458
    • Trede, M.1    Schwall, G.G.2    Saeger, H.-D.3
  • 9
    • 33751212765 scopus 로고    scopus 로고
    • 1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience
    • discussion 210-1
    • Winter JM, Cameron JL, Campbell KA, et al. 1423 pancreaticoduodenectomies for pancreatic cancer: A single-institution experience. J Gastrointest Surg 2006; 10: 1199-210; discussion 210-1.
    • (2006) J Gastrointest Surg , vol.10 , pp. 1199-1210
    • Winter, J.M.1    Cameron, J.L.2    Campbell, K.A.3
  • 10
    • 0031891450 scopus 로고    scopus 로고
    • Progression of pancreatic intraductal neoplasias to infiltrating adenocarcinoma of the pancreas
    • DOI 10.1097/00000478-199802000-00003
    • Brat DJ, Lillemoe KD, Yeo CJ, Warfield PB, Hruban RH. Progression of pancreatic intraductal neoplasias to infiltrating adenocarcinoma of the pancreas. Am J Surg Pathol 1998; 22: 163-9. (Pubitemid 28113376)
    • (1998) American Journal of Surgical Pathology , vol.22 , Issue.2 , pp. 163-169
    • Brat, D.J.1    Lillemoe, K.D.2    Yeo, C.J.3    Warfield, P.B.4    Hruban, R.H.5
  • 11
    • 0032176282 scopus 로고    scopus 로고
    • Progression of atypical ductal hyperplasia/carcinoma in situ of the pancreas to invasive adenocarcinoma
    • Brockie E, Anand A, Albores-Saavedra J. Progression of atypical ductal hyperplasia/carcinoma in situ of the pancreas to invasive carcinoma. Ann Diagn Pathol 1998; 2: 286-92. (Pubitemid 128646567)
    • (1998) Annals of Diagnostic Pathology , vol.2 , Issue.5 , pp. 286-292
    • Brockie, E.1    Anand, A.2    Albores-Saavedra, J.3
  • 13
    • 0017156835 scopus 로고
    • Morphological lesions associated with human primary invasive nonendocrine pancreatic cancer
    • Cubilla AL, Fitzgerald PJ. Morphological lesions associated with human primary invasive nonendocrine pancreatic cancer. Cancer Res 1976; 36: 2690-8
    • (1976) Cancer Res , vol.36 , pp. 2690-2698
    • Cubilla, A.L.1    Fitzgerald, P.J.2
  • 21
    • 16244393689 scopus 로고    scopus 로고
    • Intestinal and oncocytic variants of pancreatic intraepithelial neoplasia. A morphological and immunohistochemical study
    • DOI 10.1016/j.anndiagpath.2004.12.002
    • Albores-Saavedra J, Wu J, Crook T, Amirkhan RH, Jones L, Hruban RH. Intestinal and oncocytic variants of pancreatic intraepithelial neoplasia. A morphological and immunohistochemical study. Ann Diagn Pathol 2005; 9: 69-76. (Pubitemid 40460740)
    • (2005) Annals of Diagnostic Pathology , vol.9 , Issue.2 , pp. 69-76
    • Albores-Saavedra, J.1    Wu, J.2    Crook, T.3    Amirkhan, R.H.4    Jones, L.5    Hruban, R.H.6
  • 22
    • 0142072036 scopus 로고    scopus 로고
    • Clinicopathological Correlates of Pancreatic Intraepithelial Neoplasia: A Comparative Analysis of 82 Cases With and 152 Cases Without Pancreatic Ductal Adenocarcinoma
    • DOI 10.1097/01.MP.0000087422.24733.62
    • Andea A, Sarkar F, Adsay VN. Clinicopathological correlates of pancreatic intraepithelial neoplasia: a comparative analysis of 82 cases with and 152 cases without pancreatic ductal adenocarcinoma. Mod Pathol 2003; 16: 996-1006. (Pubitemid 37280815)
    • (2003) Modern Pathology , vol.16 , Issue.10 , pp. 996-1006
    • Andea, A.1    Sarkar, F.2    Adsay, V.N.3
  • 23
    • 0032748508 scopus 로고    scopus 로고
    • Duct changes and K-ras mutations in the disease-free pancreas: Analysis of type, age relation and spatial distribution
    • Luttges J, Reinecke-Luthge A, Mollmann B, et al. Duct changes and K-ras mutations in the disease-free pancreas: analysis of type, age relation and spatial distribution. Virchows Arch 1999; 435: 461-8.
    • (1999) Virchows Arch , vol.435 , pp. 461-468
    • Luttges, J.1    Reinecke-Luthge, A.2    Mollmann, B.3
  • 24
    • 0018742498 scopus 로고
    • Relation of pancreatic duct hyperplasia to carcinoma
    • DOI 10.1002/1097-0142(197904)43:4<1418::AID-CNCR2820430431>3.0. CO;2-O
    • Kozuka S, Sassa R, Taki T, et al. Relation of pancreatic duct hyperplasia to carcinoma. Cancer 1979; 43: 1418-28. (Pubitemid 9180309)
    • (1979) Cancer , vol.43 , Issue.4 , pp. 1418-1428
    • Kozuka, S.1    Sassa, R.2    Taki, T.3
  • 25
    • 75349104828 scopus 로고    scopus 로고
    • Pathology analysis reveals that dysplastic pancreatic ductal lesions are frequent in patients with hereditary pancreatitis
    • Rebours V, Levy P, Mosnier JF, et al. Pathology analysis reveals that dysplastic pancreatic ductal lesions are frequent in patients with hereditary pancreatitis. Clin Gastroenterol Hepatol 2010; 8: 206-12.
    • (2010) Clin Gastroenterol Hepatol , vol.8 , pp. 206-212
    • Rebours, V.1    Levy, P.2    Mosnier, J.F.3
  • 26
    • 73349085542 scopus 로고    scopus 로고
    • Increased prevalence of precursor lesions in familial pancreatic cancer patients
    • Shi C, Klein AP, Goggins M, et al. Increased prevalence of precursor lesions in familial pancreatic cancer patients. Clin Cancer Res 2009; 15: 7737-43.
    • (2009) Clin Cancer Res , vol.15 , pp. 7737-7743
    • Shi, C.1    Klein, A.P.2    Goggins, M.3
  • 27
    • 33645058219 scopus 로고    scopus 로고
    • The prevalence of pancreatic intraepithelial neoplasia in pancreata with uncommon types of primary neoplasms
    • DOI 10.1097/01.pas.0000180440.41280.a5, PII 0000047820060100000006
    • Stelow EB, Adams RB, Moskaluk CA. The prevalence of pancreatic intraepithelial neoplasia in pancreata with uncommon types of primary neoplasms. Am J Surg Pathol 2006; 30: 36-41. (Pubitemid 43740207)
    • (2006) American Journal of Surgical Pathology , vol.30 , Issue.1 , pp. 36-41
    • Stelow, E.B.1    Adams, R.B.2    Moskaluk, C.A.3
  • 28
    • 0026808451 scopus 로고
    • K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster
    • Cerny WL, Mangold KA, Scarpelli DG. K-ras mutation is an early event in pancreatic duct carcinogenesis in the Syrian golden hamster. Cancer Res 1992; 52: 4507-13.
    • (1992) Cancer Res , vol.52 , pp. 4507-4513
    • Cerny, W.L.1    Mangold, K.A.2    Scarpelli, D.G.3
  • 30
    • 78049398107 scopus 로고    scopus 로고
    • Distant metastasis occurs late during the genetic evolution of pancreatic cancer
    • Yachida S, Jones S, Bozic I, et al. Distant metastasis occurs late during the genetic evolution of pancreatic cancer. Nature 2010; 467: 1114-7.
    • (2010) Nature , vol.467 , pp. 1114-1117
    • Yachida, S.1    Jones, S.2    Bozic, I.3
  • 31
    • 0037298925 scopus 로고    scopus 로고
    • Molecular pathogenesis of precursor lesions of pancreatic ductal adenocarcinoma
    • DOI 10.1080/003130202201472
    • Biankin AV, Kench JG, Biankin SA, Dijkman FP, Henshall SM, Sutherland RL. Molecular pathogenesis of precursor Lesions of pancreatic ductal adenocarcinoma. Pathology 2003; 35: 14-24. (Pubitemid 36349941)
    • (2003) Pathology , vol.35 , Issue.1 , pp. 14-24
    • Biankin, A.V.1    Kench, J.G.2    Dijkman, F.P.3    Biankin, S.A.4    Henshall, S.M.5
  • 33
    • 80052253515 scopus 로고    scopus 로고
    • College of American Pathologists. Cancer Protocols: Pancreas (Exocrine)
    • College of American Pathologists. Cancer Protocols: Pancreas (Exocrine). Northfield, IL: CAP, 2009.
    • (2009) Northfield, IL: CAP
  • 35
    • 57449105155 scopus 로고    scopus 로고
    • Pancreatic intraepithelial neoplasia revisited and updated
    • Sipos B, Frank S, Gress T, Hahn S, Kloppel G. Pancreatic intraepithelial neoplasia revisited and updated. Pancreatology 2009; 9: 45-54.
    • (2009) Pancreatology , vol.9 , pp. 45-54
    • Sipos, B.1    Frank, S.2    Gress, T.3    Hahn, S.4    Kloppel, G.5
  • 37
    • 0023506974 scopus 로고
    • Ductal adenocarcinoma of the head of the pancreas: Incidence of tumor involvement beyond the Whipple resection line Histological and immunocytochemical analysis of 37 total pancreatectomy specimens
    • Kloppel G, Lohse T, Bosslet K, Ruckert K. Ductal adenocarcinoma of the head of the pancreas: incidence of tumor involvement beyond the Whipple resection line. Histological and immunocytochemical analysis of 37 total pancreatectomy specimens. Pancreas 1987; 2: 170-5.
    • (1987) Pancreas , vol.2 , pp. 170-175
    • Kloppel, G.1    Lohse, T.2    Bosslet, K.3    Ruckert, K.4
  • 38
    • 0037805547 scopus 로고    scopus 로고
    • RAS oncogenes: The first 30 years
    • DOI 10.1038/nrc1097
    • Malumbres M, Barbacid M. RAS oncogenes: the first 30 years. Nat Rev Cancer 2003; 3: 459-65. (Pubitemid 37328850)
    • (2003) Nature Reviews Cancer , vol.3 , Issue.6 , pp. 459-465
    • Malumbres, M.1    Barbacid, M.2
  • 40
  • 43
    • 13444274253 scopus 로고    scopus 로고
    • Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: A meta-analysis
    • DOI 10.1593/neo.04445
    • Lohr M, Kloppel G, Maisonneuve P, Lowenfels AB, Luttges J. Frequency of K-ras mutations in pancreatic intraductal neoplasias associated with pancreatic ductal adenocarcinoma and chronic pancreatitis: a meta-analysis. Neoplasia 2005; 7: 17-23. (Pubitemid 40209467)
    • (2005) Neoplasia , vol.7 , Issue.1 , pp. 17-23
    • Lohr, M.1    Kloppel, G.2    Maisonneuve, P.3    Lowenfels, A.B.4    Luttges, J.5
  • 47
    • 24144457548 scopus 로고    scopus 로고
    • Assessment of HER-2 status in pancreatic adenocarcinoma: Correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival
    • DOI 10.1097/01.pas.0000160979.85457.73
    • Saxby AJ, Nielsen A, Scarlett CJ, et al. Assessment of HER-2 status in pancreatic adenocarcinoma: correlation of immunohistochemistry, quantitative real-time RT-PCR, and FISH with aneuploidy and survival. Am J Surg Pathol 2005; 29: 1125-34. (Pubitemid 41232983)
    • (2005) American Journal of Surgical Pathology , vol.29 , Issue.9 , pp. 1125-1134
    • Saxby, A.J.1    Nielsen, A.2    Scarlett, C.J.3    Clarkson, A.4    Morey, A.5    Gill, A.6    Smith, R.C.7
  • 48
    • 0141742113 scopus 로고    scopus 로고
    • Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray
    • DOI 10.1097/01.MP.0000086072.56290.FB
    • Maitra A, Adsay NV, Argani P, et al. Multicomponent analysis of the pancreatic adenocarcinoma progression model using a pancreatic intraepithelial neoplasia tissue microarray. Mod Pathol 2003; 16: 902-12. (Pubitemid 37152020)
    • (2003) Modern Pathology , vol.16 , Issue.9 , pp. 902-912
    • Maitra, A.1    Adsay, N.V.2    Argani, P.3    Iacobuzio-Donahue, C.4    De Marzo, A.5    Cameron, J.L.6    Yeo, C.J.7    Hruban, R.H.8
  • 49
    • 0030715322 scopus 로고    scopus 로고
    • ECM and cell surface proteolysis: Regulating cellular ecology
    • Werb Z. ECM and cell surface proteolysis: regulating cellular ecology. Cell 1997; 91: 439-42. (Pubitemid 27508232)
    • (1997) Cell , vol.91 , Issue.4 , pp. 439-442
    • Werb, Z.1
  • 50
    • 0036266409 scopus 로고    scopus 로고
    • Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas
    • DOI 10.1172/JCI200215051
    • Crawford HC, Scoggins CR, Washington MK, Matrisian LM, Leach SD. Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas. J Clin Invest 2002; 109: 1437-44. (Pubitemid 34596169)
    • (2002) Journal of Clinical Investigation , vol.109 , Issue.11 , pp. 1437-1444
    • Crawford, H.C.1    Scoggins, C.R.2    Kay Washington, M.3    Matrisian, L.M.4    Leach, S.D.5
  • 53
    • 62249126245 scopus 로고    scopus 로고
    • Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis: Of mice and men
    • Ottenhof NA, Milne AN, Morsink FH, et al. Pancreatic intraepithelial neoplasia and pancreatic tumorigenesis: of mice and men. Arch Pathol Lab Med 2009; 133: 375-81.
    • (2009) Arch Pathol Lab Med , vol.133 , pp. 375-381
    • Ottenhof, N.A.1    Milne, A.N.2    Morsink, F.H.3
  • 54
    • 0034051469 scopus 로고    scopus 로고
    • Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations
    • DOI 10.1002/(SICI)1098-2264(200004)27:4<358::AID-GCC4>3.0.CO;2-O
    • Lal G, Liu L, Hogg D, Lassam NJ, Redston MS, Gallinger S. Patients with both pancreatic adenocarcinoma and melanoma may harbor germline CDKN2A mutations. Genes Chromosomes Cancer 2000; 27: 358-61. (Pubitemid 30127623)
    • (2000) Genes Chromosomes and Cancer , vol.27 , Issue.4 , pp. 358-361
    • Lal, G.1    Liu, L.2    Hogg, D.3    Lassam, N.J.4    Redston, M.S.5    Gallinger, S.6
  • 55
    • 0032900535 scopus 로고    scopus 로고
    • Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma
    • DOI 10.1038/5082
    • Liu L, Dilworth D, Gao L, et al. Mutation of the CDKN2A 5' UTR creates an aberrant initiation codon and predisposes to melanoma. Nat Genet 1999; 21: 128-32. (Pubitemid 29036299)
    • (1999) Nature Genetics , vol.21 , Issue.1 , pp. 128-132
    • Liu, L.1    Dilworth, D.2    Gao, L.3    Monzon, J.4    Summers, A.5    Lassam, N.6    Hogg, D.7
  • 56
    • 23044485887 scopus 로고    scopus 로고
    • Concordant loss of MTAP and p16/CDKN2A expression in pancreatic intraepithelial neoplasia: Evidence of homozygous deletion in a noninvasive precursor lesion
    • DOI 10.1038/modpathol.3800377
    • Hustinx SR, Leoni LM, Yeo CJ, et al. Concordant loss of MTAP and p16/ CDKN2A expression in pancreatic intraepithelial neoplasia: evidence of homozygous deletion in a noninvasive precursor lesion. Mod Pathol 2005; 18: 959-63. (Pubitemid 41059957)
    • (2005) Modern Pathology , vol.18 , Issue.7 , pp. 959-963
    • Hustinx, S.R.1    Leoni, L.M.2    Yeo, C.J.3    Brown, P.N.4    Goggins, M.5    Kern, S.E.6    Hruban, R.H.7    Maitra, A.8
  • 57
    • 0029129816 scopus 로고
    • Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations
    • Goldstein AM, Fraser MC, Struewing JP, et al. Increased risk of pancreatic cancer in melanoma-prone kindreds with p16INK4 mutations. N Engl J Med 1995; 333: 970-4.
    • (1995) N Engl J Med , vol.333 , pp. 970-974
    • Goldstein, A.M.1    Fraser, M.C.2    Struewing, J.P.3
  • 58
    • 0035487104 scopus 로고    scopus 로고
    • The INK4a/ARF network in tumour suppression
    • DOI 10.1038/35096061
    • Sherr CJ. The INK4a/ARF network in tumour suppression. Nat Rev Mol Cell Biol 2001; 2: 731-7. (Pubitemid 33679835)
    • (2001) Nature Reviews Molecular Cell Biology , vol.2 , Issue.10 , pp. 731-737
    • Sherr, C.J.1
  • 64
    • 0028152702 scopus 로고
    • Expression of p53 protein in precursor lesions and adenocarcinoma of human pancreas
    • Boschman CR, Stryker S, Reddy JK, Rao MS. Expression of p53 protein in precursor lesions and adenocarcinoma of human pancreas. Am J Pathol 1994; 145: 1291-5. (Pubitemid 24378483)
    • (1994) American Journal of Pathology , vol.145 , Issue.6 , pp. 1291-1295
    • Boschman, C.R.1    Stryker, S.2    Reddy, J.K.3    Rao, M.S.4
  • 65
    • 0030593038 scopus 로고    scopus 로고
    • DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
    • Hahn SA, Schutte M, Hoque AT, et al. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 1996; 271: 350-3.
    • (1996) Science , vol.271 , pp. 350-353
    • Hahn, S.A.1    Schutte, M.2    Hoque, A.T.3
  • 70
    • 0242499448 scopus 로고    scopus 로고
    • Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer
    • Siegel PM, Massague J. Cytostatic and apoptotic actions of TGF-beta in homeostasis and cancer. Nat Rev Cancer 2003; 3: 807-21.
    • (2003) Nat Rev Cancer , vol.3 , pp. 807-821
    • Siegel, P.M.1    Massague, J.2
  • 71
    • 0035863426 scopus 로고    scopus 로고
    • Transforming growth factor-β1 induces desmoplasia in an experimental model of human pancreatic carcinoma
    • Lohr M, Schmidt C, Ringel J, et al. Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma. Cancer Res 2001; 61: 550-5. (Pubitemid 32128613)
    • (2001) Cancer Research , vol.61 , Issue.2 , pp. 550-555
    • Lohr, M.1    Schmidt, C.2    Ringel, J.3    Kluth, M.4    Muller, P.5    Nizze, H.6    Jesnowski, R.7
  • 73
    • 0033842724 scopus 로고    scopus 로고
    • BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: Evidence and implications
    • Goggins M, Hruban RH, Kern SE. BRCA2 is inactivated late in the development of pancreatic intraepithelial neoplasia: evidence and implications. Am J Pathol 2000; 156: 1767-71. (Pubitemid 30646713)
    • (2000) American Journal of Pathology , vol.156 , Issue.5 , pp. 1767-1771
    • Goggins, M.1    Hruban, R.H.2    Kern, S.E.3
  • 74
    • 0036230171 scopus 로고    scopus 로고
    • Direct correlation between proliferative activity and dysplasia in pancreatic intraepithelial neoplasia (panIN): Additional evidence for a recently proposed model of progression
    • DOI 10.1038/modpathol.3880544
    • Klein WM, Hruban RH, Klein-Szanto AJ, Wilentz RE. Direct correlation between proliferative activity and dysplasia in pancreatic intraepithelial neoplasia (PanIN): additional evidence for a recently proposed model of progression. Mod Pathol 2002; 15: 441-7. (Pubitemid 34326953)
    • (2002) Modern Pathology , vol.15 , Issue.4 , pp. 441-447
    • Klein, W.M.1    Hruban, R.H.2    Klein-Szanto, A.J.P.3    Wilentz, R.E.4
  • 75
    • 0022993622 scopus 로고
    • 'Ductectatic' mucinous cystadenoma and cystadenocarcinoma of the pancreas
    • Itai Y, Ohhashi K, Nagai H, et al. ''Ductectatic'' mucinous cystadenoma and cystadenocarcinoma of the pancreas. Radiology 1986; 161: 697-700. (Pubitemid 17200420)
    • (1986) Radiology , vol.161 , Issue.3 , pp. 697-700
    • Itai, Y.1    Ohhashi, K.2    Nagai, H.3
  • 76
    • 0000491695 scopus 로고
    • Four cases of ''mucin producing'' cancer of the pancreas on specific findings of the papilla of Vater
    • Ohhashi K, Murakami Y, Takekoshi T. Four cases of ''mucin producing'' cancer of the pancreas on specific findings of the papilla of Vater. Prog Dig Endosc 1982; 20: 348-51.
    • (1982) Prog Dig Endosc , vol.20 , pp. 348-351
    • Ohhashi, K.1    Murakami, Y.2    Takekoshi, T.3
  • 80
    • 0025861605 scopus 로고
    • Intraductal mucin-hypersecreting neoplasms of the pancreas: A clinicopathological study of eight patients
    • Rickaert F, Cremer M, Deviere J, et al. Intraductal mucin-hypersecreting neoplasms of the pancreas: a clinicopathological study of eight patients. Gastroenterology 1991; 101: 512-9.
    • (1991) Gastroenterology , vol.101 , pp. 512-519
    • Rickaert, F.1    Cremer, M.2    Deviere, J.3
  • 81
    • 0025768960 scopus 로고
    • Mucinous cystic tumors and mucinous ductal ectasia of the pancreas
    • Warshaw AL. Mucinous cystic tumors and mucinous ductal ectasia of the pancreas. Gastrointest Endosc 1991; 37: 199-201.
    • (1991) Gastrointest Endosc , vol.37 , pp. 199-201
    • Warshaw, A.L.1
  • 84
    • 0028597442 scopus 로고
    • Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: An investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients
    • Sessa F, Solcia E, Capella C, et al. Intraductal papillary-mucinous tumours represent a distinct group of pancreatic neoplasms: an investigation of tumour cell differentiation and K-ras, p53 and c-erbB-2 abnormalities in 26 patients. Virchows Arch 1994; 425: 357-67.
    • (1994) Virchows Arch , vol.425 , pp. 357-367
    • Sessa, F.1    Solcia, E.2    Capella, C.3
  • 87
    • 0026639915 scopus 로고
    • The mucus-hypersecreting tumor of the pancreas Development and extension visualized by three-dimensional computerised mapping
    • Furukawa T, Takahashi T, Kobari M, Matsuno S. The mucus-hypersecreting tumor of the pancreas. Development and extension visualized by three-dimensional computerised mapping. Cancer 1992; 70: 1505-13.
    • (1992) Cancer , vol.70 , pp. 1505-1513
    • Furukawa, T.1    Takahashi, T.2    Kobari, M.3    Matsuno, S.4
  • 88
    • 0030897242 scopus 로고    scopus 로고
    • Intraductal papillary-mucinous neoplasm of the pancreas: A report of five cases with immunohistochemical findings
    • DOI 10.1080/00313029700169454
    • Kench JG, Eckstein RP, Smith RC. Intraductal papillary-mucinous neoplasm of the pancreas: a report of five cases with immunohistochemical findings. Pathology 1997; 29: 7-11. (Pubitemid 27135820)
    • (1997) Pathology , vol.29 , Issue.1 , pp. 7-11
    • Kench, J.G.1    Eckstein, R.P.2    Smith, R.C.3
  • 89
    • 0028902553 scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas associated with so-called ''mucinous ductal ectasia''. Histochemical and immunohistochemical analysis of 29 cases
    • Nagai E, Ueki T, Chijiiwa K, Tanaka M, Tsuneyoshi M. Intraductal papillary mucinous neoplasms of the pancreas associated with so-called ''mucinous ductal ectasia''. Histochemical and immunohistochemical analysis of 29 cases. Am J Surg Pathol 1995; 19: 576-89.
    • (1995) Am J Surg Pathol , vol.19 , pp. 576-589
    • Nagai, E.1    Ueki, T.2    Chijiiwa, K.3    Tanaka, M.4    Tsuneyoshi, M.5
  • 90
    • 0025915833 scopus 로고
    • Mucin-hypersecreting tumor of the pancreas with mucin extrusion through an enlarged papilla
    • Yamaguchi K, Tanaka M. Mucin-hypersecreting tumor of the pancreas with mucin extrusion through an enlarged papilla. Am J Gastroenterol 1991; 86: 835-9.
    • (1991) Am J Gastroenterol , vol.86 , pp. 835-839
    • Yamaguchi, K.1    Tanaka, M.2
  • 91
    • 0033982054 scopus 로고    scopus 로고
    • Mucinous cystic neoplasm of the pancreas or intraductal papillary- mucinous tumour of the pancreas
    • Yamaguchi K, Yokohata K, Noshiro H, Chijiiwa K, Tanaka M. Mucinous cystic neoplasm of the pancreas or intraductal papillary-mucinous tumour of the pancreas. Eur J Surg 2000; 166: 141-8. (Pubitemid 30096871)
    • (2000) European Journal of Surgery , vol.166 , Issue.2 , pp. 141-148
    • Yamaguchi, K.1    Yokohata, K.2    Noshiro, H.3    Chijiiwa, K.4    Tanaka, M.5
  • 93
    • 0031878639 scopus 로고    scopus 로고
    • Mucin-producing pancreatic tumors: Comparison of MR cholangiopancreatography with endoscopic retrograde cholangiopancreatography
    • Koito K, Namieno T, Ichimura T, et al. Mucin-producing pancreatic tumors: comparison of MR cholangiopancreatography with endoscopic retrograde cholangiopancreatography. Radiology 1998; 208: 231-7.
    • (1998) Radiology , vol.208 , pp. 231-237
    • Koito, K.1    Namieno, T.2    Ichimura, T.3
  • 94
    • 0037703747 scopus 로고    scopus 로고
    • Mucus is a predictor of better prognosis and survival in patients with intraductal papillary mucinous tumor of the pancreas
    • discussion 18-9
    • Kitagawa Y, Unger TA, Taylor S, Kozarek RA, Traverso LW. Mucus is a predictor of better prognosis and survival in patients with intraductal papillary mucinous tumor of the pancreas. J Gastrointest Surg 2003; 7: 12-8; discussion 18-9.
    • (2003) J Gastrointest Surg , vol.7 , pp. 12-18
    • Kitagawa, Y.1    Unger, T.A.2    Taylor, S.3    Kozarek, R.A.4    Traverso, L.W.5
  • 96
    • 0036142203 scopus 로고    scopus 로고
    • Intraductal papillary-mucinous neoplasms of the pancreas: An analysis of in situ and invasive carcinomas in 28 patients
    • DOI 10.1002/cncr.10203
    • Adsay NV, Conlon KC, Zee SY, Brennan MF, Klimstra DS. Intraductal papillary-mucinous neoplasms of the pancreas: an analysis of in situ and invasive carcinomas in 28 patients. Cancer 2002; 94: 62-77. (Pubitemid 34049043)
    • (2002) Cancer , vol.94 , Issue.1 , pp. 62-77
    • Volkan Adsay, N.1    Conlon, K.C.2    Zee, S.Y.3    Brennan, M.F.4    Klimstra, D.S.5
  • 97
    • 33644976385 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas: Effect of invasion and pancreatic margin status on recurrence and survival
    • Raut CP, Cleary KR, Staerkel GA, et al. Intraductal papillary mucinous neoplasms of the pancreas: effect of invasion and pancreatic margin status on recurrence and survival. Ann Surg Oncol 2006; 13: 582-94.
    • (2006) Ann Surg Oncol , vol.13 , pp. 582-594
    • Raut, C.P.1    Cleary, K.R.2    Staerkel, G.A.3
  • 99
    • 2442717796 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas: An updated experience
    • discussion 97-9
    • Sohn TA, Yeo CJ, Cameron JL, et al. Intraductal papillary mucinous neoplasms of the pancreas: an updated experience. Ann Surg 2004; 239: 788-97; discussion 97-9.
    • (2004) Ann Surg , vol.239 , pp. 788-797
    • Sohn, T.A.1    Yeo, C.J.2    Cameron, J.L.3
  • 100
  • 104
    • 0025000288 scopus 로고
    • Cystic tumors of the pancreas New clinical, radiologic, and pathologic observations in 67 patients
    • discussion 444-5
    • Warshaw AL, Compton CC, Lewandrowski K, Cardenosa G, Mueller PR. Cystic tumors of the pancreas. New clinical, radiologic, and pathologic observations in 67 patients. Ann Surg 1990; 212: 432-43; discussion 444-5.
    • (1990) Ann Surg , vol.212 , pp. 432-443
    • Warshaw, A.L.1    Compton, C.C.2    Lewandrowski, K.3    Cardenosa, G.4    Mueller, P.R.5
  • 105
    • 0032955877 scopus 로고    scopus 로고
    • Mucinous cystic neoplasm (mucinous cystadenocarcinoma of low-grade malignant potential) of the pancreas: A clinicopathologic study of 130 cases
    • DOI 10.1097/00000478-199901000-00001
    • Thompson LD, Becker RC, Przygodzki RM, Adair CF, Heffess CS. Mucinous cystic neoplasm (mucinous cystadenocarcinoma of low-grade malignant potential) of the pancreas: a clinicopathologic study of 130 cases. Am J Surg Pathol 1999; 23: 1-16. (Pubitemid 29025236)
    • (1999) American Journal of Surgical Pathology , vol.23 , Issue.1 , pp. 1-16
    • Thompson, L.D.R.1    Becker, R.C.2    Przygodzki, R.M.3    Adair, C.F.4    Heffess, C.S.5
  • 109
    • 28244441643 scopus 로고    scopus 로고
    • Frozen sectioning of the pancreatic cut surface during resection of intraductal papillary mucinous neoplasms of the pancreas is useful and reliable: A prospective evaluation
    • discussion 78-80
    • Couvelard A, Sauvanet A, Kianmanesh R, et al. Frozen sectioning of the pancreatic cut surface during resection of intraductal papillary mucinous neoplasms of the pancreas is useful and reliable: a prospective evaluation. Ann Surg 2005; 242: 774-8; discussion 78-80.
    • (2005) Ann Surg , vol.242 , pp. 774-778
    • Couvelard, A.1    Sauvanet, A.2    Kianmanesh, R.3
  • 110
    • 0034760640 scopus 로고    scopus 로고
    • Surgical management of intraductal papillary mucinous tumors of the pancreas: The role of routine frozen section of the surgical margin, intraoperative endoscopic staged biopsies of the Wirsung duct, and pancreaticogastric anastomosis
    • Gigot JF, Deprez P, Sempoux C, et al. Surgical management of intraductal papillary mucinous tumors of the pancreas: the role of routine frozen section of the surgical margin, intraoperative endoscopic staged biopsies of theWirsung duct, and pancreaticogastric anastomosis. Arch Surg 2001; 136: 1256-62. (Pubitemid 33043512)
    • (2001) Archives of Surgery , vol.136 , Issue.11 , pp. 1256-1262
    • Gigot, J.-F.1    Deprez, P.2    Sempoux, C.3    Descamps, C.4    Metairie, S.5    Glineur, D.6    Gianello, P.7
  • 111
    • 0034014801 scopus 로고    scopus 로고
    • Intraductal papillary mucinous tumors of the pancreas: Pancreatic resections guided by preoperative morphological assessment and intraoperative frozen section examination
    • Paye F, Sauvanet A, Terris B, et al. Intraductal papillary mucinous tumors of the pancreas: pancreatic resections guided by preoperative morphological assessment and intraoperative frozen section examination. Surgery 2000; 127: 536-44. (Pubitemid 30257512)
    • (2000) Surgery , vol.127 , Issue.5 , pp. 536-544
    • Paye, F.1    Sauvanet, A.2    Terris, B.3    Ponsot, P.4    Vilgrain, V.5    Hammel, P.6    Bernades, P.7    Ruszniewski, P.8    Belghiti, J.9
  • 113
    • 1242341489 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas: An analysis of clinicopathologic features and outcome
    • DOI 10.1097/01.sla.0000114132.47816.dd
    • D'Angelica M, Brennan MF, Suriawinata AA, Klimstra D, Conlon KC. Intraductal papillary mucinous neoplasms of the pancreas: an analysis of clinicopathologic features and outcome. Ann Surg 2004; 239: 400-8. (Pubitemid 38229071)
    • (2004) Annals of Surgery , vol.239 , Issue.3 , pp. 400-408
    • D'Angelica, M.1    Brennan, M.F.2    Suriawinata, A.A.3    Klimstra, D.4    Conlon, K.C.5
  • 115
    • 67649406252 scopus 로고    scopus 로고
    • Invasive intraductal papillarymucinous neoplasm of the pancreas: Comparison with pancreatic ductal adenocarcinoma
    • Murakami Y, Uemura K, Sudo T, et al. Invasive intraductal papillarymucinous neoplasm of the pancreas: comparison with pancreatic ductal adenocarcinoma. J Surg Oncol 2009; 100: 13-8.
    • (2009) J Surg Oncol , vol.100 , pp. 13-18
    • Murakami, Y.1    Uemura, K.2    Sudo, T.3
  • 116
    • 77649125847 scopus 로고    scopus 로고
    • Histopathologic basis for the favorable survival after resection of intraductal papillary mucinous neoplasm-associated invasive adenocarcinoma of the pancreas
    • Poultsides GA, Reddy S, Cameron JL, et al. Histopathologic basis for the favorable survival after resection of intraductal papillary mucinous neoplasm-associated invasive adenocarcinoma of the pancreas. Ann Surg 2010; 251: 470-6.
    • (2010) Ann Surg , vol.251 , pp. 470-476
    • Poultsides, G.A.1    Reddy, S.2    Cameron, J.L.3
  • 117
    • 33646711886 scopus 로고    scopus 로고
    • Invasive carcinoma originating in an intraductal papillary mucinous neoplasm of the pancreas: A clinicopathologic comparison with a common type of invasive ductal carcinoma
    • Shimada K, Sakamoto Y, Sano T, Kosuge T, Hiraoka N. Invasive carcinoma originating in an intraductal papillary mucinous neoplasm of the pancreas: a clinicopathologic comparison with a common type of invasive ductal carcinoma. Pancreas 2006; 32: 281-7.
    • (2006) Pancreas , vol.32 , pp. 281-287
    • Shimada, K.1    Sakamoto, Y.2    Sano, T.3    Kosuge, T.4    Hiraoka, N.5
  • 118
    • 0034857973 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas: An increasingly recognized clinicopathologic entity
    • DOI 10.1097/00000658-200109000-00005
    • Sohn TA, Yeo CJ, Cameron JL, Iacobuzio-Donahue C, Hruban RH, Lillemoe KD. Intraductal papillary mucinous neoplasms of the pancreas: an increasingly recognised pathologic entity. Ann Surg 2001; 234: 313-22. (Pubitemid 32847068)
    • (2001) Annals of Surgery , vol.234 , Issue.3 , pp. 313-322
    • Sohn, T.A.1    Yeo, C.J.2    Cameron, J.L.3    Iacobuzio-Donahue, C.A.4    Hruban, R.H.5    Lillemoe, K.D.6
  • 119
    • 38149095828 scopus 로고    scopus 로고
    • Survival and prognosis of invasive intraductal papillary mucinous neoplasms of the pancreas: Comparison with pancreatic ductal adenocarcinoma
    • Woo SM, Ryu JK, Lee SH, et al. Survival and prognosis of invasive intraductal papillary mucinous neoplasms of the pancreas: comparison with pancreatic ductal adenocarcinoma. Pancreas 2008; 36: 50-5.
    • (2008) Pancreas , vol.36 , pp. 50-55
    • Woo, S.M.1    Ryu, J.K.2    Lee, S.H.3
  • 120
    • 78049234682 scopus 로고    scopus 로고
    • Molecular pathogenesis of intraductal papillary mucinous neoplasms of the pancreas
    • Thosani N, Dasari CS, Bhutani MS, Raimondo M, Guha S. Molecular pathogenesis of intraductal papillary mucinous neoplasms of the pancreas. Pancreas 2010; 39: 1129-33.
    • (2010) Pancreas , vol.39 , pp. 1129-1133
    • Thosani, N.1    Dasari, C.S.2    Bhutani, M.S.3    Raimondo, M.4    Guha, S.5
  • 121
    • 77956156618 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasms of the pancreas
    • 13 e1-2
    • Fernandez-del Castillo C, Adsay NV. Intraductal papillary mucinous neoplasms of the pancreas. Gastroenterology 2010; 139: 708-13; 13 e1-2.
    • (2010) Gastroenterology , vol.139 , pp. 708-713
    • Fernandez-Del Castillo, C.1    Adsay, N.V.2
  • 123
    • 0034653608 scopus 로고    scopus 로고
    • The PI3K-PBK1 connection: More than just a road to PKB
    • DOI 10.1042/0264-6021:3460561
    • Vanhaesebroeck B, Alessi DR. The PI3K-PDK1 connection: more than just a road to PKB. Biochem J 2000; 346 (Pt 3): 561-76. (Pubitemid 30171014)
    • (2000) Biochemical Journal , vol.346 , Issue.3 , pp. 561-576
    • Vanhaesebroeck, B.1    Alessi, D.R.2
  • 124
    • 0037380304 scopus 로고    scopus 로고
    • Phosphorylated Akt/PKB controls cell growth and apoptosis in intraductal papillary-mucinous tumor and invasive ductal adenocarcinoma of the pancreas
    • DOI 10.1097/00006676-200304000-00008
    • Semba S, Moriya T, Kimura W, Yamakawa M. Phosphorylated Akt/PKB controls cell growth and apoptosis in intraductal papillary-mucinous tumor and invasive ductal adenocarcinoma of the pancreas. Pancreas 2003; 26: 250-7. (Pubitemid 36384157)
    • (2003) Pancreas , vol.26 , Issue.3 , pp. 250-257
    • Semba, S.1    Moriya, T.2    Kimura, W.3    Yamakawa, M.4
  • 125
    • 0029921032 scopus 로고    scopus 로고
    • K-ras mutation and p53 protein accumulation in intraductal mucin-hypersecreting neoplasms of the pancreas
    • Satoh K, Shimosegawa T, Moriizumi S, Koizumi M, Toyota T. K-ras mutation and p53 protein accumulation in intraductal mucin-hypersecreting neoplasms of the pancreas. Pancreas 1996; 12: 362-8.
    • (1996) Pancreas , vol.12 , pp. 362-368
    • Satoh, K.1    Shimosegawa, T.2    Moriizumi, S.3    Koizumi, M.4    Toyota, T.5
  • 129
    • 24044529771 scopus 로고    scopus 로고
    • Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas
    • DOI 10.1038/modpathol.3800383
    • Furukawa T, Fujisaki R, Yoshida Y, et al. Distinct progression pathways involving the dysfunction of DUSP6/MKP-3 in pancreatic intraepithelial neoplasia and intraductal papillary-mucinous neoplasms of the pancreas. Mod Pathol 2005; 18: 1034-42. (Pubitemid 41224493)
    • (2005) Modern Pathology , vol.18 , Issue.8 , pp. 1034-1042
    • Furukawa, T.1    Fujisaki, R.2    Yoshida, Y.3    Kanai, N.4    Sunamura, M.5    Abe, T.6    Takeda, K.7    Matsuno, S.8    Horii, A.9
  • 133
    • 64049089987 scopus 로고    scopus 로고
    • Molecular classification of neoplasms of the pancreas
    • Hruban RH, Adsay NV. Molecular classification of neoplasms of the pancreas. Hum Pathol 2009; 40: 612-23.
    • (2009) Hum Pathol , vol.40 , pp. 612-623
    • Hruban, R.H.1    Adsay, N.V.2
  • 135
    • 0035018972 scopus 로고    scopus 로고
    • Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal tumorigenesis
    • DOI 10.1002/gcc.1147
    • Inoue H, Furukawa T, Sunamura M, Takeda K, Matsuno S, Horii A. Exclusion of SMAD4 mutation as an early genetic change in human pancreatic ductal tumorigenesis. Genes Chromosomes Cancer 2001; 31: 295-9. (Pubitemid 32521761)
    • (2001) Genes Chromosomes and Cancer , vol.31 , Issue.3 , pp. 295-299
    • Inoue, H.1    Furukawa, T.2    Sunamura, M.3    Takeda, K.4    Matsuno, S.5    Horii, A.6
  • 137
    • 0018102267 scopus 로고
    • Mucinous cystic neoplasms of the pancreas with overt and latent malignancy (cystadenocarcinoma and cystadenoma). A clinicopathologic study of 41 cases
    • Compagno J, Oertel JE. Mucinous cystic neoplasms of the pancreas with overt and latent malignancy (cystadenocarcinoma and cystadenoma). A clinicopathologic study of 41 cases. Am J Clin Pathol 1978; 69: 573-80. (Pubitemid 8366915)
    • (1978) American Journal of Clinical Pathology , vol.69 , Issue.6 , pp. 573-580
    • Compagno, J.1    Oertel, J.E.2
  • 139
    • 78650960917 scopus 로고    scopus 로고
    • Clinicopathological features and prognosis of mucinous cystic neoplasm with ovarian-type stroma: A multi-institutional study of the Japan Pancreas Society
    • Yamao K, Yanagisawa A, Takahashi K, et al. Clinicopathological features and prognosis of mucinous cystic neoplasm with ovarian-type stroma: a multi-institutional study of the Japan Pancreas Society. Pancreas 2011; 40: 67-71.
    • (2011) Pancreas , vol.40 , pp. 67-71
    • Yamao, K.1    Yanagisawa, A.2    Takahashi, K.3
  • 142
    • 0344838433 scopus 로고    scopus 로고
    • Incidental pancreatic cysts: Clinicopathologic characteristics and comparison with symptomatic patients
    • discussion 33-4
    • Fernandez-del Castillo C, Targarona J, Thayer SP, Rattner DW, Brugge WR, Warshaw AL. Incidental pancreatic cysts: clinicopathologic characteristics and comparison with symptomatic patients. Arch Surg 2003; 138: 427-33; discussion 33-4.
    • (2003) Arch Surg , vol.138 , pp. 427-433
    • Fernandez-Del Castillo, C.1    Targarona, J.2    Thayer, S.P.3    Rattner, D.W.4    Brugge, W.R.5    Warshaw, A.L.6
  • 143
    • 0036209038 scopus 로고    scopus 로고
    • The mucin profile of noninvasive and invasive mucinous cystic neoplasms of the pancreas
    • DOI 10.1097/00000478-200204000-00008
    • Luttges J, Feyerabend B, Buchelt T, Pacena M, Kloppel G. The mucin profile of noninvasive and invasive mucinous cystic neoplasms of the pancreas. Am J Surg Pathol 2002; 26: 466-71. (Pubitemid 34280119)
    • (2002) American Journal of Surgical Pathology , vol.26 , Issue.4 , pp. 466-471
    • Luttges, J.1    Feyerabend, B.2    Buchelt, T.3    Pacena, M.4    Kloppel, G.5
  • 144
    • 0030886967 scopus 로고    scopus 로고
    • Intraductal papillary tumors and mucinous cystic tumors of the pancreas: Clinicopathologic study of 38 cases
    • DOI 10.1016/S0046-8177(97)90053-8
    • Fukushima N, Mukai K, Kanai Y, et al. Intraductal papillary tumors and mucinous cystic tumors of the pancreas: clinicopathologic study of 38 cases. Hum Pathol 1997; 28: 1010-7. (Pubitemid 27388101)
    • (1997) Human Pathology , vol.28 , Issue.9 , pp. 1010-1017
    • Fukushima, N.1    Mukai, K.2    Kanai, Y.3    Hasebe, T.4    Shimada, K.5    Ozaki, H.6    Kinoshita, T.7    Kosuge, T.8
  • 145
    • 0033504891 scopus 로고    scopus 로고
    • Cystadenomas and cystadenocarcinomas of the pancreas: A multiinstitutional retrospective study of 398 cases
    • DOI 10.1097/00000658-199908000-00004
    • Le Borgne J, de Calan L, Partensky C. Cystadenomas and cystadenocarcinomas of the pancreas: a multiinstitutional retrospective study of 398 cases. French Surgical Association. Ann Surg 1999; 230: 152-61. (Pubitemid 30191880)
    • (1999) Annals of Surgery , vol.230 , Issue.2 , pp. 152-161
    • Le Borgne, J.1    De Calan, L.2    Partensky, C.3
  • 146
    • 0342684450 scopus 로고    scopus 로고
    • Anaplastic carcinoma occurring in association with a mucinous cystic neoplasm of the pancreas
    • Lane RB Jr, Sangueza OP. Anaplastic carcinoma occurring in association with a mucinous cystic neoplasm of the pancreas. Arch Pathol Lab Med 1997; 121: 533-5. (Pubitemid 27215160)
    • (1997) Archives of Pathology and Laboratory Medicine , vol.121 , Issue.5 , pp. 533-535
    • Lane Jr., R.B.1    Sangueza, O.P.2
  • 147
    • 0035375037 scopus 로고    scopus 로고
    • Detection and tumor staging of malignancy in cystic, intraductal, and solid tumors of the pancreas by EUS
    • Brandwein SL, Farrell JJ, Centeno BA, Brugge WR. Detection and tumor staging of malignancy in cystic, intraductal, and solid tumors of the pancreas by EUS. Gastrointest Endosc 2001; 53: 722-7. (Pubitemid 33717244)
    • (2001) Gastrointestinal Endoscopy , vol.53 , Issue.7 , pp. 722-727
    • Brandwein, S.L.1    Farrell, J.J.2    Centeno, B.A.3    Brugge, W.R.4
  • 149
    • 11144252244 scopus 로고    scopus 로고
    • Fine-needle aspiration cytology of intraductal papillary-mucinous tumors: A retrospective analysis
    • DOI 10.1002/dc.20149
    • Layfield LJ, Cramer H. Fine-needle aspiration cytology of intraductal papillary-mucinous tumors: a retrospective analysis. Diagn Cytopathol 2005; 32: 16-20. (Pubitemid 40024068)
    • (2005) Diagnostic Cytopathology , vol.32 , Issue.1 , pp. 16-20
    • Layfield, L.J.1    Cramer, H.2
  • 151
    • 33745218780 scopus 로고    scopus 로고
    • Intraductal papillary mucinous neoplasm of the pancreas: Cytologic features predict histologic grade
    • Michaels PJ, Brachtel EF, Bounds BC, Brugge WR, Bishop Pitman M. Intraductal papillary mucinous neoplasm of the pancreas: cytologic features predict histologic grade. Cancer 2006; 108: 163-73.
    • (2006) Cancer , vol.108 , pp. 163-173
    • Michaels, P.J.1    Brachtel, E.F.2    Bounds, B.C.3    Brugge, W.R.4    Bishop Pitman, M.5
  • 152
    • 17144419287 scopus 로고    scopus 로고
    • Pitfalls in endoscopic ultrasound-guided fine-needle aspiration and how to avoid them
    • DOI 10.1097/01.pap.0000155053.68496.ad
    • Stelow EB, Bardales RH, Stanley MW. Pitfalls in endoscopic ultrasoundguided fine-needle aspiration and how to avoid them. Adv Anat Pathol 2005; 12: 62-73. (Pubitemid 40515794)
    • (2005) Advances in Anatomic Pathology , vol.12 , Issue.2 , pp. 62-73
    • Stelow, E.B.1    Bardales, R.H.2    Stanley, M.W.3
  • 153
    • 85047688916 scopus 로고    scopus 로고
    • Intraductal Papillary-Mucinous Neoplasm of the Pancreas: The Findings and Limitations of Cytologic Samples Obtained by Endoscopic Ultrasound-Guided Fine-Needle Aspiration
    • DOI 10.1309/CEPK-542W-3885-2LP8
    • Stelow EB, Stanley MW, Bardales RH, et al. Intraductal papillarymucinous neoplasm of the pancreas. The findings and limitations of cytologic samples obtained by endoscopic ultrasound-guided fine-needle aspiration. Am J Clin Pathol 2003; 120: 398-404. (Pubitemid 37295111)
    • (2003) American Journal of Clinical Pathology , vol.120 , Issue.3 , pp. 398-404
    • Stelow, E.B.1    Stanley, M.W.2    Bardales, R.H.3    Mallery, S.4    Lai, R.5    Linzie, B.M.6    Pambuccian, S.E.7
  • 154
    • 1842864110 scopus 로고    scopus 로고
    • Fine-needle aspiration cytology of mucinous tumors of the pancreas
    • DOI 10.1002/cncr.20052
    • Recine M, Kaw M, Evans DB, Krishnamurthy S. Fine-needle aspiration cytology of mucinous tumors of the pancreas. Cancer 2004; 102: 92-9. (Pubitemid 38489966)
    • (2004) Cancer , vol.102 , Issue.2 , pp. 92-99
    • Recine, M.1    Kaw, M.2    Evans, D.B.3    Krishnamurthy, S.4
  • 155
    • 33750504449 scopus 로고    scopus 로고
    • Pancreatic mucinous lesions: A retrospective analysis with cytohistological correlation
    • DOI 10.1002/dc.20561
    • Zhai J, Sarkar R, Ylagan L. Pancreatic mucinous lesions: a retrospective analysis with cytohistological correlation. Diagn Cytopathol 2006; 34: 724-30. (Pubitemid 44663246)
    • (2006) Diagnostic Cytopathology , vol.34 , Issue.11 , pp. 724-730
    • Zhai, J.1    Sarkar, R.2    Ylagan, L.3
  • 158
    • 0033759142 scopus 로고    scopus 로고
    • Dpc4 protein in mucinous cystic neoplasms of the pancreas: Frequent loss of expression in invasive carcinomas suggests a role in genetic progression
    • Iacobuzio-Donahue CA, Wilentz RE, Argani P, et al. Dpc4 protein in mucinous cystic neoplasms of the pancreas: frequent loss of expression in invasive carcinomas suggests a role in genetic progression. Am J Surg Pathol 2000; 24: 1544-8.
    • (2000) Am J Surg Pathol , vol.24 , pp. 1544-1548
    • Iacobuzio-Donahue, C.A.1    Wilentz, R.E.2    Argani, P.3
  • 159
    • 0033497531 scopus 로고    scopus 로고
    • Sequential accumulation of K-ras mutations and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy
    • discussion 9-11
    • Jimenez RE, Warshaw AL, Z'Graggen K, et al. Sequential accumulation of K-ras mutations and p53 overexpression in the progression of pancreatic mucinous cystic neoplasms to malignancy. Ann Surg 1999; 230: 501-9; discussion 9-11.
    • (1999) Ann Surg , vol.230 , pp. 501-509
    • Jimenez, R.E.1    Warshaw, A.L.2    Z'graggen, K.3
  • 160
    • 0242522859 scopus 로고    scopus 로고
    • Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas
    • DOI 10.1097/01.MP.0000094088.37888.A6
    • Kim SG, Wu TT, Lee JH, et al. Comparison of epigenetic and genetic alterations in mucinous cystic neoplasm and serous microcystic adenoma of pancreas. Mod Pathol 2003; 16: 1086-94. (Pubitemid 37414202)
    • (2003) Modern Pathology , vol.16 , Issue.11 , pp. 1086-1094
    • Kim, S.G.1    Wu, T.-T.2    Lee, J.H.3    Yun, Y.K.4    Issa, J.-P.5    Hamilton, S.R.6    Rashid, A.7
  • 162
    • 0023959795 scopus 로고
    • Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life
    • Finlay CA, Hinds PW, Tan TH, Eliyahu D, Oren M, Levine AJ. Activating mutations for transformation by p53 produce a gene product that forms an hsc70-p53 complex with an altered half-life. Mol Cell Biol 1988; 8: 531-9.
    • (1988) Mol Cell Biol , vol.8 , pp. 531-539
    • Finlay, C.A.1    Hinds, P.W.2    Tan, T.H.3    Eliyahu, D.4    Oren, M.5    Levine, A.J.6
  • 163
    • 0029793889 scopus 로고    scopus 로고
    • p53 protein expression and DNA ploidy in cystic tumors of the pancreas
    • Flejou JF, Boulange B, Bernades P, Belghiti J, Henin D. p53 protein expression and DNA ploidy in cystic tumors of the pancreas. Pancreas 1996; 13: 247-52. (Pubitemid 26317993)
    • (1996) Pancreas , vol.13 , Issue.3 , pp. 247-252
    • Flejou, J.-F.1    Boulange, B.2    Bernades, P.3    Belghiti, J.4    Henin, D.5
  • 165
    • 33645824724 scopus 로고    scopus 로고
    • Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse
    • Bardeesy N, Aguirre AJ, Chu GC, et al. Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse. Proc Natl Acad Sci USA 2006; 103: 5947-52.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 5947-5952
    • Bardeesy, N.1    Aguirre, A.J.2    Chu, G.C.3
  • 168
    • 67149143399 scopus 로고    scopus 로고
    • Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer
    • Olive KP, Jacobetz MA, Davidson CJ, et al. Inhibition of Hedgehog signaling enhances delivery of chemotherapy in a mouse model of pancreatic cancer. Science 2009; 324: 1457-61.
    • (2009) Science , vol.324 , pp. 1457-1461
    • Olive, K.P.1    Jacobetz, M.A.2    Davidson, C.J.3
  • 169
    • 0038405066 scopus 로고    scopus 로고
    • Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice
    • Grippo PJ, Nowlin PS, Demeure MJ, Longnecker DS, Sandgren EP. Preinvasive pancreatic neoplasia of ductal phenotype induced by acinar cell targeting of mutant Kras in transgenic mice. Cancer Res 2003; 63:2016-9. (Pubitemid 36538599)
    • (2003) Cancer Research , vol.63 , Issue.9 , pp. 2016-2019
    • Grippo, P.J.1    Nowlin, P.S.2    Demeure, M.J.3    Longnecker, D.S.4    Sandgren, E.P.5
  • 172
    • 78649291031 scopus 로고    scopus 로고
    • TuvesonDA. Deploying mouse models of pancreatic cancer for chemoprevention studies
    • Grippo PJ, TuvesonDA. Deploying mouse models of pancreatic cancer for chemoprevention studies. Cancer Prev Res (Phila) 2010; 3: 1382-7.
    • (2010) Cancer Prev Res (Phila) , vol.3 , pp. 1382-1387
    • Grippo, P.J.1
  • 173
    • 77951115122 scopus 로고    scopus 로고
    • International Cancer Genome Consortium et al International network of cancer genome projects
    • International Cancer Genome Consortium et al. International network of cancer genome projects. Nature 2010; 464: 993-8.
    • (2010) Nature , vol.464 , pp. 993-998
  • 174
    • 47649101549 scopus 로고    scopus 로고
    • Improving outcomes for operable pancreatic cancer: Is access to safer surgery the problem?
    • DOI 10.1111/j.1440-1746.2008.05471.x
    • Chang DK, Merrett ND, Biankin AV;. NSW Pancreatic Cancer Network. Improving outcomes for operable pancreatic cancer: is access to safer surgery the problem? J Gastroenterol Hepatol 2008; 23: 1036-45. (Pubitemid 352019387)
    • (2008) Journal of Gastroenterology and Hepatology , vol.23 , Issue.7 PART 1 , pp. 1036-1045
    • Chang, D.K.1    Merrett, N.D.2    Biankin, A.V.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.