-
1
-
-
0000152018
-
Generalized intestinal polyposis and melanin spots of the oral mucosa, lip and digits: A syndrome of diagnostic significance
-
Jeghers H, McKusick VA, Katz KH: Generalized intestinal polyposis and melanin spots of the oral mucosa, lip and digits: a syndrome of diagnostic significance. N Engl J Med 1949, 241:1031-1036
-
(1949)
N Engl J Med
, vol.241
, pp. 1031-1036
-
-
Jeghers, H.1
McKusick, V.A.2
Katz, K.H.3
-
2
-
-
0023192463
-
Increased risk of cancer in the Peutz-Jeghers syndrome
-
Giardiello FM, Welsh SB, Hamilton SR, Offerhaus GJA, Gittelsohn AM, Booker SV, Krush AJ, Yardley JH, Luk GD: Increased risk of cancer in the Peutz-Jeghers syndrome. N Engl J Med 1987, 316:1511-1514
-
(1987)
N Engl J Med
, vol.316
, pp. 1511-1514
-
-
Giardiello, F.M.1
Welsh, S.B.2
Hamilton, S.R.3
Offerhaus, G.J.A.4
Gittelsohn, A.M.5
Booker, S.V.6
Krush, A.J.7
Yardley, J.H.8
Luk, G.D.9
-
3
-
-
0027494333
-
Cancer in Peutz-Jeghers syndrome
-
Hizawa K, Iida M, Matsumoto T, Kohrogi N, Kinoshita H, Yao T, Fujishima M: Cancer in Peutz-Jeghers syndrome. Cancer 1993, 72: 2777-2781
-
(1993)
Cancer
, vol.72
, pp. 2777-2781
-
-
Hizawa, K.1
Iida, M.2
Matsumoto, T.3
Kohrogi, N.4
Kinoshita, H.5
Yao, T.6
Fujishima, M.7
-
4
-
-
15444350943
-
Increased risk for cancer in patients with the Peutz-Jeghers syndrome
-
Boardman LA, Thibodeau SN, Schaid DJ, Lindor NM, McDonnell SK, Burgart LJ, Ahlquist DA, Podratz KC, Pittelkow M, Hartmann LC: Increased risk for cancer in patients with the Peutz-Jeghers syndrome. Ann Intern Med 1998, 128:896-899
-
(1998)
Ann Intern Med
, vol.128
, pp. 896-899
-
-
Boardman, L.A.1
Thibodeau, S.N.2
Schaid, D.J.3
Lindor, N.M.4
McDonnell, S.K.5
Burgart, L.J.6
Ahlquist, D.A.7
Podratz, K.C.8
Pittelkow, M.9
Hartmann, L.C.10
-
6
-
-
0031012344
-
Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis
-
Hemminki A, Tomlinson I, Markie D, Jarvinen H, Sistonen P, Bjorkqvist A-M, Knuutila S, Salovaara R, Bodmer W, Shibata D, de la Chapelle A, Aaltonen LA: Localization of a susceptibility locus for Peutz-Jeghers syndrome to 19p using comparative genomic hybridization and targeted linkage analysis. Nat Genet 1997, 15:87-90
-
(1997)
Nat Genet
, vol.15
, pp. 87-90
-
-
Hemminki, A.1
Tomlinson, I.2
Markie, D.3
Jarvinen, H.4
Sistonen, P.5
Bjorkqvist, A.-M.6
Knuutila, S.7
Salovaara, R.8
Bodmer, W.9
Shibata, D.10
De La Chapelle, A.11
Aaltonen, L.A.12
-
7
-
-
0030820394
-
Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p
-
Amos CI, Bali D, Thiel TJ, Anderson JP, Gourley I, Frazier ML, Lynch PM, Luchtefeld MA, Young A, McGarrity TJ, Seldin MF: Fine mapping of a genetic locus for Peutz-Jeghers syndrome on chromosome 19p. Cancer Res 1997, 57:3653-3656
-
(1997)
Cancer Res
, vol.57
, pp. 3653-3656
-
-
Amos, C.I.1
Bali, D.2
Thiel, T.J.3
Anderson, J.P.4
Gourley, I.5
Frazier, M.L.6
Lynch, P.M.7
Luchtefeld, M.A.8
Young, A.9
McGarrity, T.J.10
Seldin, M.F.11
-
8
-
-
0031974516
-
Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase
-
Jenne DE, Reimann H, Nezu J, Friedel W, Loff S, Jeschke R, Muller O, Back W, Zimmer M: Peutz-Jeghers syndrome is caused by mutations in a novel serine threonine kinase. Nat Genet 1998, 18:38-43
-
(1998)
Nat Genet
, vol.18
, pp. 38-43
-
-
Jenne, D.E.1
Reimann, H.2
Nezu, J.3
Friedel, W.4
Loff, S.5
Jeschke, R.6
Muller, O.7
Back, W.8
Zimmer, M.9
-
9
-
-
0032495530
-
A serine/ threonine kinase gene defective in Peutz-Jeghers syndrome
-
Hemminki A, Markie D, Tomlinson I, Avizienyte E, Roth S, Loukola A, Bignell G, Warren W, Aminoff M, Hoglund P, Jarvinen H: A serine/ threonine kinase gene defective in Peutz-Jeghers syndrome. Nature 1998, 391:184-187
-
(1998)
Nature
, vol.391
, pp. 184-187
-
-
Hemminki, A.1
Markie, D.2
Tomlinson, I.3
Avizienyte, E.4
Roth, S.5
Loukola, A.6
Bignell, G.7
Warren, W.8
Aminoff, M.9
Hoglund, P.10
Jarvinen, H.11
-
10
-
-
0021879645
-
Hereditary cancer, oncogenes, and antioncogenes
-
Knudson AG, Jr: Hereditary cancer, oncogenes, and antioncogenes. Cancer Res 1985, 45:1437-1443
-
(1985)
Cancer Res
, vol.45
, pp. 1437-1443
-
-
Knudson A.G. Jr1
-
11
-
-
0008944606
-
Frequent somatic mutation in serine/threonine kinase 11/Peutz-Jeghers syndrome gene left-sided colon cancer
-
Dong SM, Kim KM, Kim SY, Shin MS, Y. NE, Lee SH, Park WS, Yoo NJ, Jang JJ, Yoon CY, Kim JW, Kim SY, Yang YM, Kim SH, Kim CS, Lee JY: Frequent somatic mutation in serine/threonine kinase 11/Peutz-Jeghers syndrome gene left-sided colon cancer. Cancer Res 1998, 58:3787-3790
-
(1998)
Cancer Res
, vol.58
, pp. 3787-3790
-
-
Dong, S.M.1
Kim, K.M.2
Kim, S.Y.3
Shin, M.S.4
Ne, Y.5
Lee, S.H.6
Park, W.S.7
Yoo, N.J.8
Jang, J.J.9
Yoon, C.Y.10
Kim, J.W.11
Kim, S.Y.12
Yang, Y.M.13
Kim, S.H.14
Kim, C.S.15
Lee, J.Y.16
-
12
-
-
0031827021
-
Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes
-
Wang Z-J, Taylor F, Churchman M, Norbury G, Tomlinson I: Genetic pathways of colorectal carcinogenesis rarely involve the PTEN and LKB1 genes outside the inherited hamartoma syndromes. Am J Pathol 1998, 153:363-366
-
(1998)
Am J Pathol
, vol.153
, pp. 363-366
-
-
Wang, Z.-J.1
Taylor, F.2
Churchman, M.3
Norbury, G.4
Tomlinson, I.5
-
13
-
-
0032523997
-
Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors
-
Avizienyte E, Roth S, Loukola A, Hemminki A, Lothe RA, Stenwig AE, Fossa SD, Salovaara R, Aaltonen LA: Somatic mutations in LKB1 are rare in sporadic colorectal and testicular tumors. Cancer Res 1998, 58:2087-2090
-
(1998)
Cancer Res
, vol.58
, pp. 2087-2090
-
-
Avizienyte, E.1
Roth, S.2
Loukola, A.3
Hemminki, A.4
Lothe, R.A.5
Stenwig, A.E.6
Fossa, S.D.7
Salovaara, R.8
Aaltonen, L.A.9
-
14
-
-
0032054770
-
Low frequency of somatic mutations in the LKB/Peutz-Jeghers syndrome gene in sporadic breast cancer
-
Bignell GR, Barfoot R, Seal S, Collins N, Warren W, Stratton MR: Low frequency of somatic mutations in the LKB/Peutz-Jeghers syndrome gene in sporadic breast cancer. Cancer Res 1998, 58:1384-1386
-
(1998)
Cancer Res
, vol.58
, pp. 1384-1386
-
-
Bignell, G.R.1
Barfoot, R.2
Seal, S.3
Collins, N.4
Warren, W.5
Stratton, M.R.6
-
15
-
-
0033012429
-
Novel mutation in the LKBI/STKII gene in Dutch Peutz-Jeghers families
-
in press
-
Westerman AM, Entius MM, Boor PPC, Koole H, de Baar E, Offerhaus GJA, Lindhout D. Halley DJJ, de Rooij FWM, Wilson JHP: Novel mutation in the LKBI/STKII gene in Dutch Peutz-Jeghers families. Hum Mutat 1999 (in press)
-
(1999)
Hum Mutat
-
-
Westerman, A.M.1
Entius, M.M.2
Boor, P.P.C.3
Koole, H.4
De Baar, E.5
Offerhaus, G.J.A.6
Lindhout, D.7
Halley, D.J.J.8
De Rooij, F.W.M.9
Wilson, J.H.P.10
-
16
-
-
0028059330
-
Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma
-
Caldas C, Hahn SA, da Costa LT, Redston MS, Schutte M, Seymour AB, Weinstein CL, Hruban RH, Yeo CJ, Kern SE: Frequent somatic mutations and homozygous deletions of the p16 (MTS1) gene in pancreatic adenocarcinoma. Nat Genet 1994, 8:27-31
-
(1994)
Nat Genet
, vol.8
, pp. 27-31
-
-
Caldas, C.1
Hahn, S.A.2
Da Costa, L.T.3
Redston, M.S.4
Schutte, M.5
Seymour, A.B.6
Weinstein, C.L.7
Hruban, R.H.8
Yeo, C.J.9
Kern, S.E.10
-
17
-
-
0029041032
-
Identified by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region
-
Schutte M, da Costa LT, Hahn SA, Moskaluk C, Hoque ATMS, Rozenblum E, Weinstein CL, Bittner M, Meltzer PS, Trent JM, Yeo CJ, Hruban RH, Kern SE: Identified by representational difference analysis of a homozygous deletion in pancreatic carcinoma that lies within the BRCA2 region. Proc Natl Acad Sci USA 1995, 92:5950-5954
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 5950-5954
-
-
Schutte, M.1
Da Costa, L.T.2
Hahn, S.A.3
Moskaluk, C.4
Hoque, A.5
Rozenblum, E.6
Weinstein, C.L.7
Bittner, M.8
Meltzer, P.S.9
Trent, J.M.10
Yeo, C.J.11
Hruban, R.H.12
Kern, S.E.13
-
18
-
-
0040061124
-
Cytogenetic and fluorescence in situ hybridization analyses of chromosome 19 aberrations in pancreatic carcinomas: Frequent loss of 19p13.3 and gain of 19q13.1-13.2
-
Hoglund M, Gorunova L, Andren-Sandberg A, Dawiskiba S, Mitelman F, Johansson B: Cytogenetic and fluorescence in situ hybridization analyses of chromosome 19 aberrations in pancreatic carcinomas: frequent loss of 19p13.3 and gain of 19q13.1-13.2. Genes Chromosomes Cancer 1998, 21:8-16
-
(1998)
Genes Chromosomes Cancer
, vol.21
, pp. 8-16
-
-
Hoglund, M.1
Gorunova, L.2
Andren-Sandberg, A.3
Dawiskiba, S.4
Mitelman, F.5
Johansson, B.6
-
19
-
-
14444284330
-
Tumor-suppressive pathways in pancreatic carcinoma
-
Rozenblum E, Schutte M, Goggins M, Hahn SA, Lu J, Panzer S, Zahurak M, Goodman SN, Hruban RH, Yeo CJ, Kern SE: Tumor-suppressive pathways in pancreatic carcinoma. Cancer Res 1997, 57:1731-1734
-
(1997)
Cancer Res
, vol.57
, pp. 1731-1734
-
-
Rozenblum, E.1
Schutte, M.2
Goggins, M.3
Hahn, S.A.4
Lu, J.5
Panzer, S.6
Zahurak, M.7
Goodman, S.N.8
Hruban, R.H.9
Yeo, C.J.10
Kern, S.E.11
-
20
-
-
0030593038
-
DPC4, a candidate tumor-suppressor gene at 18q21.1
-
Hahn SA, Schutte M, Hoque ATMS, Moskaluk CA, da Costa LT, Rozenblum E, Weinstein CL, Fischer A, Yeo CJ, Hruban RH, Kern SE: DPC4, a candidate tumor-suppressor gene at 18q21.1. Science 1996, 271:350-353
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
21
-
-
0028342395
-
Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia
-
Caldas C, Hahn SA, Hruban RH, Redston MS, Yeo CJ, Kern SE: Detection of K-ras mutations in the stool of patients with pancreatic adenocarcinoma and pancreatic ductal hyperplasia. Cancer Res 1994, 54:3563-3573
-
(1994)
Cancer Res
, vol.54
, pp. 3563-3573
-
-
Caldas, C.1
Hahn, S.A.2
Hruban, R.H.3
Redston, M.S.4
Yeo, C.J.5
Kern, S.E.6
-
22
-
-
0032100617
-
Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene
-
Su GH, Hilgers W, Shekher MC, Tang DJ, Yeo CJ, Hruban RH, Kern SE: Alterations in pancreatic, biliary, and breast carcinomas support MKK4 as a genetically targeted tumor suppressor gene. Cancer Res 1998, 58:2339-2342
-
(1998)
Cancer Res
, vol.58
, pp. 2339-2342
-
-
Su, G.H.1
Hilgers, W.2
Shekher, M.C.3
Tang, D.J.4
Yeo, C.J.5
Hruban, R.H.6
Kern, S.E.7
|