Pathologic examination accurately predicts prognosis in mucinous cystic neoplasms of the pancreas

American Journal of Surgical Pathology

Volumn 23, Issue 11, 1999, Pages 1320-1327

  Wilentz, Robb E ^a   Albores Saavedra, Jorge ^b   Zahurak, Marianna ^a   Talamini, Mark A ^a   Yeo, Charles J ^a   Cameron, John L ^a   Hruban, Ralph H ^a,c  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Invasive mucinous cystadenocarcinoma; Mucinous cystadenoma; Mucinous cystic neoplasm; Pancreas; Prognosis

Indexed keywords

ADULT; AGED; ARTICLE; CANCER INVASION; CANCER RECURRENCE; CANCER SURVIVAL; CYSTADENOCARCINOMA; CYSTADENOMA; DISEASE CLASSIFICATION; FEMALE; HISTOLOGY; HUMAN; HUMAN TISSUE; MAJOR CLINICAL STUDY; MALE; METASTASIS; PANCREAS TUMOR; PROGNOSIS; TUMOR BIOPSY;

ADENOCARCINOMA, MUCINOUS; AGED; FEMALE; HUMANS; MALE; MIDDLE AGED; PANCREATIC NEOPLASMS; PREDICTIVE VALUE OF TESTS; PROGNOSIS; SURVIVAL RATE;

EID: 0032703611     PISSN: 01475185     EISSN: None     Source Type: Journal    
DOI: 10.1097/00000478-199911000-00002     Document Type: Article

References (42)

1. Albores-Saavedra J, Angeles-Angeles A, Nadji M, Henson DE, Alvarez L. Mucinous cystadenocarcinoma of the pancreas. Morphologic and immunocytochemical observations. Am J Surg Pathol 1987;11:11-20.
2. Albores-Saavedra J, Gould EW, Angeles-Angeles A, Henson DE. Cystic tumors of the pancreas. Pathol Annu 1990;25:19-50.
3. Albores-Saavedra J, Nadji M, Henson DE, Angeles-Angeles A. Entero-endocrine cell differentiation in carcinomas of the gallbladder and mucinous cystadenocarcinomas of the pancreas. Pathol Res Pract 1998;183:169-75.
4. Bartsch D, Bastian D, Barth P, et al. K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas. Ann Surg 1998;228:79-86.
5. Becker WF, Welsh RA, Pratt HS. Cystadenoma and cystadenocarcinoma of the pancreas. Ann Surg 1965;161:845-63.
6. Compagno J, Oertel JE. Microcystic adenomas of the pancreas (glycogen-rich cystadenomas). A clinicopathologic study of 34 cases. Am J Clin Pathol 1978;69:289-98.
7. Compagno J, Oertel JE. Mucinous cystic neoplasms of the pancreas with oven and latent malignancy (cystadenocarcinoma and cystadenoma). A clinicopathologic study of 41 cases. Am J Clin Pathol 1978;69:573-80.
8. Corbally MT, McAnena OJ, Urmacher C, Herman B, Shiu MH. Pancreatic cystadenoma. A clinicopathologic study. Arch Surg 1989;124:1271-4.
9. Cox DR. Regression models and life tables (with discussion). J R Stat Soc 1972;34:187-220.
10. Cubilla AL, Fitzgerald PJ. Tumors of the exocrine pancreas, 2nd series. Washington: Armed Forces Institute of Pathology, 1984.
11. Cullen PK Jr, ReMine WH, Dahlin DC. A clinicopathologic study of cystadenocarcinoma of the pancreas. Surg Gynecol Obstet 1963; 117:189-95.
12. DiGiuseppe JA, Yeo CJ, Hruban RH. Molecular biology and the diagnosis and treatment of adenocarcinoma of the pancreas. Adv Anat Pathol 1996;3:139-55.
13. Fearon ER, Vogelstein B. A genetic model for colorectal tumorigenesis. Cell 1990;61:759-67.
14. Flejou JF, Boulange B, Bemades P, Belghiti J, Henin D. p53 protein expression and DNA ploidy in cystic tumors of the pancreas. Pancreas 1996;13:247-52.
15. Hruban RH, Offerhaus GJA, Graves T, Parnes H, Albores-Saavedra J. Molecular pathology of early pancreatic cancer. In: Scrivastava S, Henson DE, Gazdar A, eds. Molecular pathology of early cancer. Amsterdam: IOS Press, 1999:288-298.
16. Hruban RH, Westra WH, Phelps TH, Isacson C. Surgical pathology dissection: an illustrated guide. New York: Springer-Verlag, 1996.
17. Hruban RH, Wilentz RE. Pancreas. In: Weidner N, Cote RJ, Suster S, Weiss LM, eds. Modern surgical pathology. Philadelphia: WB Saunders, 1999, in press.
18. Hruban RH, Wilentz RE, Goggins M, Offerhaus GJA, Yeo CJ, Kern SE. Pathology of incipient pancreatic cancer. Ann Oncol 1999;10:59-511.
19. Hyde GL, Davis JB, McMillin RD, McMillin M. Mucinous cystic-neoplasm of the pancreas with latent malignancy. Am Surg 1984; 50:225-9.
20. Ishak KG, Willis GW, Cummins SD, Bullock AA. Biliary cystadenoma and cystadenocarcinoma. Report of 14 cases and review of the literature. Cancer 1977;39:322-38.
21. Kaplan EL, Meier P. Nonparametric estimation from incomplete observations. J Am Stat Assoc 1958;53:457-80.
22. Katoh H, Rossi RL, Braasch JW, Munson JL, Shimozawa E, Tanabe T. Cystadenoma and cystadenocarcinoma of the pancreas. Hepatogastroenterology 1989;36:424-30.
23. Klimstra D, Longnecker DS. K-ras mutations in pancreatic ductal proliferative lesions. Am J Pathol 1994;145:1547-50.
24. Klöppel G, Solcia E, Longnecker DS, Capella C, Sobin LH. World Health Organization international hislological classification of tumors. Berlin: Springer-Verlag, 1996.
25. Mantel N, Haenszel W. Statistical aspects of the analysis of data from retrospective studies of disease. J Natl Cancer Inst 1959;22: 719-48.
26. Ridder GJ, Maschek H, Flemming P, Nashan B, Klempnauer J. Ovarian-like stroma in an invasive mucinous cystadenocarcinoma of the pancreas positive for inhibin. A hint concerning its possible pathogenesis. Virchows Arch 1998;432:451-4.
27. Sachs JR, Deren JJ, Sohn M, Nusbaum M. Mucinous cystadenoma: pitfalls of differential diagnosis. Am J Gastroenterol 1989;84: 811-6.
28. SAS Institute. SAS user's guide: statistics. Cary, NC: SAS Institute, 1985.
29. Sawyer KC, Spencer JR, Lubchenco AF. Proliferative cysts of the pancreas. Ann Surg 1952;135:549-54.
30. Solcia E, Capella C, Klöppel G. Tumors of the pancreas, 3rd series. Washington: Armed Forces Institute of Pathology, 1997.
31. Statistics and Epidemiology Research Corporation. EGRET user's manual. Seattle: Statistics and Epidemiology Research Corporation, 1988.
32. Talamini MA, Moesinger R, Yeo CJ, Poulose B, Hruban RH, Cameron JL, Pitt HA. Cystadenomas of the pancreas: is enucleation an adequate operation? Ann Surg 1998;227:896-903.
33. Thompson LDR, Becker RC, Przygodzkj RM, Adair CF, Heffess CS. Mucinous cystic neoplasm (mucinous cystadenocarcinoma of low-grade malignant potential) of the pancreas: a clinicopathologic study of the pancreas. Am J Surg Pathol 1999;23:1-16.
34. Warren KW, Hardy KJ. Cystadenocarcinoma of the pancreas. Surg Gynecol Obstet 1968;127:734-6.
35. Westra WH, Sturm PJ, Drillenburg P, et al. K-ras oncogene mutations in osteoclast-like giant-cell tumors of the pancreas and liver: genetic evidence to support origin from the duct epithelium. Am J Surg Pathol 1998;22:1247-54.
36. Wilentz RE, Albores-Saavedra J, Hruban RH. The exocrine pancreas. In: Albores-Saavedra J, Henson DE, eds. The pathology of incipient neoplasia, 3rd ed. New York: Oxford, 1999, in press.
37. Wilentz RE, Chung CH, Sturm PDJ, et al. K-ras mutations in the duodenal fluid of patients with pancreatic carcinoma. Cancer 1998;82:96-103.
38. Wilentz RE, Geradts J, Maynard R, et al. Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expression. Cancer Res 1998;58:4740-4.
39. Wilentz RE, Hruban RH. Pathology of cancer of the pancreas. Surg Oncol Clin N Am 1998;7:43-65.
40. Wilentz RE, Hruban RH, Albores-Saavedra J. Prognosis of invasive mucinous cystadenocarcinomas of the pancreas: a study of over 29,000 patients from the SEER database [abstract]. Mod Pathol 1999;12:169a.
41. Yamaguchi K, Enjoji M. Cystic neoplasms of the pancreas. Gastroenterology 1987;92:1934-43.
42. Yu HC, Shetty J. Mucinous cystic neoplasm of the pancreas with high carcinoembryonic antigen. Arch Pathol Lab Med 1985;109: 375-7.