Epidemiology of renal cell cancer

Hematology/Oncology Clinics of North America

Volumn 25, Issue 4, 2011, Pages 651-665

  Cho, Eunyoung ^a,b   Adami, Hans Olov ^b,c   Lindblad, Per ^d  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^c KAROLINSKA INSTITUTE   (Sweden)

^d ÖREBRO UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Epidemiology; Hypertension; Incidence; Mortality; Obesity; Renal cell cancer; Risk factors; Smoking

Indexed keywords

ANTIHYPERTENSIVE AGENT; DIURETIC AGENT;

ALCOHOL CONSUMPTION; CANCER INCIDENCE; CANCER MORTALITY; CANCER RISK; CANCER SURVIVAL; CIGARETTE SMOKING; DIABETES MELLITUS; FAT INTAKE; FOOD INTAKE; GENETIC RISK; HUMAN; HYPERTENSION; KIDNEY CARCINOMA; KIDNEY FAILURE; OBESITY; OCCUPATIONAL HAZARD; PHYSICAL ACTIVITY; PREVALENCE; PRIORITY JOURNAL; PROTEIN INTAKE; REVIEW; SEX DIFFERENCE; SURVIVAL RATE;

CARCINOMA, RENAL CELL; EUROPE; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; INCIDENCE; KIDNEY NEOPLASMS; OBESITY; PREVALENCE; UNITED STATES;

EID: 79960343628     PISSN: 08898588     EISSN: 15581977     Source Type: Journal    
DOI: 10.1016/j.hoc.2011.04.002     Document Type: Review

References (128)

1. Curado M.P., Edwards B., Shin H.R., et al. Cancer incidence in five continent 2007, vol. 9. IARC, Lyon (France).
2. Mathew A., Devesa S.S., Fraumeni J.F., et al. Global increases in kidney cancer incidence, 1973-1992. Eur J Cancer Prev 2002, 11(2):171-178.
3. Levi F., Ferlay J., Galeone C., et al. The changing pattern of kidney cancer incidence and mortality in Europe. BJU Int 2008, 101(8):949-958.
4. Ferlay J., Shin H.R., Bray F., et al. GLOBOCAN 2008: cancer incidence and mortality worldwide 2010, International Agency for Research on Cancer, Lyon (France).
5. SEER cancer statistics review, 1975-2007. National Cancer Institute Available at:, Accessed May 20, 2011. http://seer.cancer.gov/csr/1975_2007/.
6. Jemal A., Siegel R., Xu J., et al. Cancer statistics, 2010. CA Cancer J Clin 2010, 60(5):277-300.
7. Bensalah K., Pantuck A.J., Crepel M., et al. Prognostic variables to predict cancer-related death in incidental renal tumours. BJU Int 2008, 102(10):1376-1380.
8. Sun M., Thuret R., Abdollah F., et al. Age-adjusted incidence, mortality, and survival rates of stage-specific renal cell carcinoma in North America: a trend analysis. Eur Urol 2011, 59(1):135-141.
9. Levi F., Lucchini F., Negri E., et al. Declining mortality from kidney cancer in Europe. Ann Oncol 2004, 15(7):1130-1135.
10. Chow W.H., Devesa S.S., Warren J.L., et al. Rising incidence of renal cell cancer in the United States. JAMA 1999, 281(17):1628-1631.
11. Verdecchia A., Francisci S., Brenner H., et al. Recent cancer survival in Europe: a 2000-02 period analysis of EUROCARE-4 data. Lancet Oncol 2007, 8(9):784-796.
12. Engholm G., Gislum M., Bray F., et al. Trends in the survival of patients diagnosed with cancer in the Nordic countries 1964-2003 followed up to the end of 2006. Material and methods. Acta Oncol 2010, 49(5):545-560.
13. Chow W.H., Linehan W.M., Devesa S.S. Re: Rising incidence of small renal masses: a need to reassess treatment effect. J Natl Cancer Inst 2007, 99(7):569-570. [author reply: 570-1].
14. IARC IARC monographs on the evaluation of carcinogenic risks to humans: tobacco smoke and involuntary smoking 2004, vol. 83. IARC Press, Lyon (France).
15. Hunt J.D., van der Hel O.L., McMillan G.P., et al. Renal cell carcinoma in relation to cigarette smoking: meta-analysis of 24 studies. Int J Cancer 2005, 114(1):101-108.
16. Renehan A.G., Tyson M., Egger M., et al. Body-mass index and incidence of cancer: a systematic review and meta-analysis of prospective observational studies. Lancet 2008, 371(9612):569-578.
17. Adams K.F., Leitzmann M.F., Albanes D., et al. Body size and renal cell cancer incidence in a large US Cohort Study. Am J Epidemiol 2008, 168(3):268-277.
18. Nicodemus K.K., Sweeney C., Folsom A.R. Evaluation of dietary, medical and lifestyle risk factors for incident kidney cancer in postmenopausal women. Int J Cancer 2004, 108(1):115-121.
19. Pischon T., Lahmann P.H., Boeing H., et al. Body size and risk of renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition (EPIC). Int J Cancer 2006, 118(3):728-738.
20. Mellemgaard A., Lindblad P., Schlehofer B., et al. International renal-cell cancer study. III. Role of weight, height, physical activity, and use of amphetamines. Int J Cancer 1995, 60(3):350-354.
21. Lindblad P., Wolk A., Bergstrom R., et al. The role of obesity and weight fluctuations in the etiology of renal cell cancer: a population-based case-control study. Cancer Epidemiol Biomarkers Prev 1994, 3(8):631-639.
22. Bergstrom A., Hsieh C.C., Lindblad P., et al. Obesity and renal cell cancer-a quantitative review. Br J Cancer 2001, 85(7):984-990.
23. Calle E.E., Kaaks R. Overweight, obesity and cancer: epidemiological evidence and proposed mechanisms. Nat Rev Cancer 2004, 4(8):579-591.
24. Osorio-Costa F., Rocha G.Z., Dias M.M., et al. Epidemiological and molecular mechanisms aspects linking obesity and cancer. Arq Bras Endocrinol Metabol 2009, 53(2):213-226.
25. Tulinius H., Sigfusson N., Sigvaldason H., et al. Risk factors for malignant diseases: a cohort study on a population of 22,946 Icelanders. Cancer Epidemiol Biomarkers Prev 1997, 6(11):863-873.
26. Bjorge T., Tretli S., Engeland A. Relation of height and body mass index to renal cell carcinoma in two million Norwegian men and women. Am J Epidemiol 2004, 160(12):1168-1176.
27. van Dijk B.A., Schouten L.J., Kiemeney L.A., et al. Relation of height, body mass, energy intake, and physical activity to risk of renal cell carcinoma: results from the Netherlands Cohort Study. Am J Epidemiol 2004, 160(12):1159-1167.
28. Chow W.H., Gridley G., Fraumeni J.F., et al. Obesity, hypertension, and the risk of kidney cancer in men. N Engl J Med 2000, 343(18):1305-1311.
29. Moore S.C., Chow W.H., Schatzkin A., et al. Physical activity during adulthood and adolescence in relation to renal cell cancer. Am J Epidemiol 2008, 168(2):149-157.
30. Bergstrom A., Moradi T., Lindblad P., et al. Occupational physical activity and renal cell cancer: a nationwide cohort study in Sweden. Int J Cancer 1999, 83(2):186-191.
31. Tavani A., Zucchetto A., Dal Maso L., et al. Lifetime physical activity and the risk of renal cell cancer. Int J Cancer 2007, 120(9):1977-1980.
32. Bergstrom A., Terry P., Lindblad P., et al. Physical activity and risk of renal cell cancer. Int J Cancer 2001, 92(1):155-157.
33. Menezes R.J., Tomlinson G., Kreiger N. Physical activity and risk of renal cell carcinoma. Int J Cancer 2003, 107(4):642-646.
34. Chiu B.C., Gapstur S.M., Chow W.H., et al. Body mass index, physical activity, and risk of renal cell carcinoma. Int J Obes (Lond) 2006, 30(6):940-947.
35. Augustsson K., Skog K., Jagerstad M., et al. Dietary heterocyclic amines and cancer of the colon, rectum, bladder, and kidney: a population-based study. Lancet 1999, 353(9154):703-707.
36. De Stefani E., Fierro L., Mendilaharsu M., et al. Meat intake, 'mate' drinking and renal cell cancer in Uruguay: a case-control study. Br J Cancer 1998, 78(9):1239-1243.
37. Wolk A., Gridley G., Niwa S., et al. International renal cell cancer study. VII. Role of diet. Int J Cancer 1996, 65(1):67-73.
38. Hu J., Mao Y., White K. Diet and vitamin or mineral supplements and risk of renal cell carcinoma in Canada. Cancer Causes Control 2003, 14(8):705-714.
39. Brock K.E., Gridley G., Chiu B.C., et al. Dietary fat and risk of renal cell carcinoma in the USA: a case-control study. Br J Nutr 2009, 101(8):1228-1238.
40. Faramawi M.F., Johnson E., Fry M.W., et al. Consumption of different types of meat and the risk of renal cancer: meta-analysis of case-control studies. Cancer Causes Control 2007, 18(2):125-133.
41. Hsu C.C., Chow W.H., Boffetta P., et al. Dietary risk factors for kidney cancer in eastern and central Europe. Am J Epidemiol 2007, 166(1):62-70.
42. Grieb S.M., Theis R.P., Burr D., et al. Food groups and renal cell carcinoma: results from a case-control study. J Am Diet Assoc 2009, 109(4):656-667.
43. Lee J.E., Spiegelman D., Hunter D.J., et al. Fat, protein, and meat consumption and renal cell cancer risk: a pooled analysis of 13 prospective studies. J Natl Cancer Inst 2008, 100(23):1695-1706.
44. Allen N.E., Roddam A.W., Sieri S., et al. A prospective analysis of the association between macronutrient intake and renal cell carcinoma in the European Prospective Investigation into Cancer and Nutrition. Int J Cancer 2009, 125(4):982-987.
45. Yuan J.M., Gago-Dominguez M., Castelao J.E., et al. Cruciferous vegetables in relation to renal cell carcinoma. Int J Cancer 1998, 77(2):211-216.
46. Lee J.E., Giovannucci E., Smith-Warner S.A., et al. Intakes of fruits, vegetables, vitamins A, C, and E, and carotenoids and risk of renal cell cancer. Cancer Epidemiol Biomarkers Prev 2006, 15(12):2445-2452.
47. Weikert S., Boeing H., Pischon T., et al. Fruits and vegetables and renal cell carcinoma: findings from the European prospective investigation into cancer and nutrition (EPIC). Int J Cancer 2006, 118(12):3133-3139.
48. Montella M., Tramacere I., Tavani A., et al. Coffee, decaffeinated coffee, tea intake, and risk of renal cell cancer. Nutr Cancer 2009, 61(1):76-80.
49. Lee J.E., Hunter D.J., Spiegelman D., et al. Intakes of coffee, tea, milk, soda and juice and renal cell cancer in a pooled analysis of 13 prospective studies. Int J Cancer 2007, 121(10):2246-2253.
50. Rashidkhani B., Akesson A., Lindblad P., et al. Major dietary patterns and risk of renal cell carcinoma in a prospective cohort of Swedish women. J Nutr 2005, 135(7):1757-1762.
51. Handa K., Kreiger N. Diet patterns and the risk of renal cell carcinoma. Public Health Nutr 2002, 5(6):757-767.
52. Hu J., La Vecchia C., Negri E., et al. Dietary vitamin C, E, and carotenoid intake and risk of renal cell carcinoma. Cancer Causes Control 2009, 20(8):1451-1458.
53. Lindblad P., Wolk A., Bergstrom R., et al. Diet and risk of renal cell cancer: a population-based case-control study. Cancer Epidemiol Biomarkers Prev 1997, 6(4):215-223.
54. Goodman M.T., Morgenstern H., Wynder E.L. A case-control study of factors affecting the development of renal cell cancer. Am J Epidemiol 1986, 124:926-941.
55. Parker A.S., Cerhan J.R., Lynch C.F., et al. Gender, alcohol consumption, and renal cell carcinoma. Am J Epidemiol 2002, 155(5):455-462.
56. Lee J.E., Hunter D.J., Spiegelman D., et al. Alcohol intake and renal cell cancer in a pooled analysis of 12 prospective studies. J Natl Cancer Inst 2007, 99(10):801-810.
57. Davies M.J., Baer D.J., Judd J.T., et al. Effects of moderate alcohol intake on fasting insulin and glucose concentrations and insulin sensitivity in postmenopausal women: a randomized controlled trial. JAMA 2002, 287(19):2559-2562.
58. Facchini F., Chen Y.D., Reaven G.M. Light-to-moderate alcohol intake is associated with enhanced insulin sensitivity. Diabetes Care 1994, 17(2):115-119.
59. Flaherty K.T., Fuchs C.S., Colditz G.A., et al. A prospective study of body mass index, hypertension, and smoking and the risk of renal cell carcinoma (United States). Cancer Causes Control 2005, 16:1099-1106.
60. McCredie M., Stewart J.H. Risk factors for kidney cancer in New South Wales, Australia. II. Urologic disease, hypertension, obesity, and hormonal factors. Cancer Causes Control 1992, 3(4):323-331.
61. McLaughlin J.K., Chow W.H., Mandel J.S., et al. International renal-cell cancer study. VIII. Role of diuretics, other anti-hypertensive medications and hypertension. Int J Cancer 1995, 63(2):216-221.
62. Shapiro J.A., Williams M.A., Weiss N.S., et al. Hypertension, antihypertensive medication use, and risk of renal cell carcinoma. Am J Epidemiol 1999, 149(6):521-530.
63. Yuan J.M., Castelao J.E., Gago-Dominguez M., et al. Hypertension, obesity and their medications in relation to renal cell carcinoma. Br J Cancer 1998, 77(9):1508-1513.
64. Heath C.W., Lally C.A., Calle E.E., et al. Hypertension, diuretics, and antihypertensive medications as possible risk factors for renal cell cancer. Am J Epidemiol 1997, 145(7):607-613.
65. Prineas R.J., Folsom A.R., Zhang Z.M., et al. Nutrition and other risk factors for renal cell carcinoma in postmenopausal women. Epidemiology 1997, 8(1):31-36.
66. Fryzek J.P., Poulsen A.H., Johnsen S.P., et al. A cohort study of antihypertensive treatments and risk of renal cell cancer. Br J Cancer 2005, 92(7):1302-1306.
67. Weikert S., Boeing H., Pischon T., et al. Blood pressure and risk of renal cell carcinoma in the European prospective investigation into cancer and nutrition. Am J Epidemiol 2008, 167(4):438-446.
68. Shapiro J.A., Williams M.A., Weiss N.S. Body mass index and risk of renal cell carcinoma. Epidemiology 1999, 10(2):188-191.
69. Denton M.D., Magee C.C., Ovuworie C., et al. Prevalence of renal cell carcinoma in patients with ESRD pre-transplantation: a pathologic analysis. Kidney Int 2002, 61(6):2201-2209.
70. Ishikawa I. Uremic acquired renal cystic disease. Natural history and complications. Nephron 1991, 58(3):257-267.
71. Maisonneuve P., Agodoa L., Gellert R., et al. Cancer in patients on dialysis for end-stage renal disease: an international collaborative study. Lancet 1999, 354(9173):93-99.
72. Marple J.T., MacDougall M., Chonko A.M. Renal cancer complicating acquired cystic kidney disease. J Am Soc Nephrol 1994, 4(12):1951-1956.
73. Stewart J.H., Buccianti G., Agodoa L., et al. Cancers of the kidney and urinary tract in patients on dialysis for end-stage renal disease: analysis of data from the United States, Europe, and Australia and New Zealand. J Am Soc Nephrol 2003, 14(1):197-207.
74. Doublet J.D., Peraldi M.N., Gattegno B., et al. Renal cell carcinoma of native kidneys: prospective study of 129 renal transplant patients. J Urol 1997, 158(1):42-44.
75. Kliem V., Kolditz M., Behrend M., et al. Risk of renal cell carcinoma after kidney transplantation. Clin Transplant 1997, 11(4):255-258.
76. Adami J., Gabel H., Lindelof B., et al. Cancer risk following organ transplantation: a nationwide cohort study in Sweden. Br J Cancer 2003, 89(7):1221-1227.
77. Neuzillet Y., Lay F., Luccioni A., et al. De novo renal cell carcinoma of native kidney in renal transplant recipients. Cancer 2005, 103(2):251-257.
78. Concolino G., Lubrano C., Ombres M., et al. Acquired cystic kidney disease: the hormonal hypothesis. Urology 1993, 41(2):170-175.
79. La Vecchia C., Negri E., Franceschi S., et al. A case-control study of diabetes mellitus and cancer risk. Br J Cancer 1994, 70:950-953.
80. McLaughlin J.K., Gao Y.T., Gao R.N., et al. Risk factors for renal-cell cancer in Shanghai, China. Int J Cancer 1992, 52(4):562-565.
81. Wynder E.L., Mabuchi K., Whitmore W.F. Epidemiology of adenocarcinoma of the kidney. J Natl Cancer Inst 1974, 53(6):1619-1634.
82. Asal N.R., Geyer J.R., Risser D.R., et al. Risk factors in renal cell carcinoma. II. Medical history, occupation, multivariate analysis, and conclusions. Cancer Detect Prev 1988, 13(3-4):263-279.
83. McLaughlin J.K., Mandel J.S., Blot W.J., et al. A population-based case-control study of renal cell carcinoma. J Natl Cancer Inst 1984, 72(2):275-284.
84. O'Mara B.A., Byers T., Schoenfeld E. Diabetes mellitus and cancer risk: a multisite case-control study. J Chronic Dis 1985, 38:435-441.
85. Kreiger N., Marrett L.D., Dodds L., et al. Risk factors for renal cell carcinoma: results of a population-based case-control study. Cancer Causes Control 1993, 4(2):101-110.
86. Mellemgaard A., Niwa S., Mehl E.S., et al. Risk factors for renal cell carcinoma in Denmark: role of medication and medical history. Int J Epidemiol 1994, 23(5):923-930.
87. Adami H.O., McLaughlin J., Ekbom A., et al. Cancer risk in patients with diabetes mellitus. Cancer Causes Control 1991, 2:307-314.
88. Wideroff L., Gridley G., Mellemkjaer L., et al. Cancer incidence in a population-based cohort of patients hospitalized with diabetes mellitus in Denmark. J Natl Cancer Inst 1997, 89(18):1360-1365.
89. Lindblad P., Chow W.H., Chan J., et al. The role of diabetes mellitus in the aetiology of renal cell cancer. Diabetologia 1999, 42(1):107-112.
90. Gordon S.C., Moonka D., Brown K.A., et al. Risk for renal cell carcinoma in chronic hepatitis C infection. Cancer Epidemiol Biomarkers Prev 2010, 19(4):1066-1073.
91. IARC Phenacetin and analgesic mixtures containing phenacetin; monographs on the evaluation of carcinogenic risks of chemicals to humans: an updating of IARC monographs 1987, IARC Press, Lyon (France).
92. Maclure M., MacMahon B. Phenacetin and cancer of urinary tract. N Engl J Med 1985, (313):1479.
93. McLaughlin J.K., Blot W.J., Mehl E.S., et al. Relation of analgesic use to renal cancer: population-based findings. Natl Cancer Inst Monogr 1985, 69:217-222.
94. McCredie M., Ford J.M., Stewart J.H. Risk factors for cancer of the renal parenchyma. Int J Cancer 1988, 42(1):13-16.
95. McCredie M., Stewart J.H., Day N.E. Different roles for phenacetin and paracetamol in cancer of the kidney and renal pelvis. Int J Cancer 1993, 53(2):245-249.
96. Derby L.E., Jick H. Acetaminophen and renal and bladder cancer. Epidemiology 1996, 7(4):358-362.
97. Gago-Dominguez M., Yuan J.M., Castelao J.E., et al. Regular use of analgesics is a risk factor for renal cell carcinoma. Br J Cancer 1999, 81(3):542-548.
98. Bosetti C., Gallus S., La Vecchia C. Aspirin and cancer risk: an updated quantitative review to 2005. Cancer Causes Control 2006, 17(7):871-888.
99. Cho E, Hankinson SE, Curhan GC, et al. Prospective study of use of analgesics in relation to the risk of renal cell cancer: The Nurses' Health Study and Health Professionals Follow-up Study. AACR Meeting. April 18-22, 2009 [abstract: 4864].
100. Lee J.E., Hankinson S.E., Cho E. Reproductive factors and risk of renal cell cancer: the Nurses' Health Study. Am J Epidemiol 2009, 169(10):1243-1250.
101. Lindblad P., Mellemgaard A., Schlehofer B., et al. International renal-cell cancer study. V. Reproductive factors, gynecologic operations and exogenous hormones. Int J Cancer 1995, 61(2):192-198.
102. Kabat G.C., Silvera S.A., Miller A.B., et al. A cohort study of reproductive and hormonal factors and renal cell cancer risk in women. Br J Cancer 2007, 96(5):845-849.
103. Altman D., Yin L., Johansson A., et al. Risk of renal cell carcinoma after hysterectomy. Arch Intern Med 2010, 170(22):2011-2016.
104. Chow W.H., McLaughlin J.K., Mandel J.S., et al. Reproductive factors and the risk of renal cell cancer among women. Int J Cancer 1995, 60(3):321-324.
105. Mattioli S., Truffelli D., Baldasseroni A., et al. Occupational risk factors for renal cell cancer: a case-control study in northern Italy. J Occup Environ Med 2002, 44(11):1028-1036.
106. Pesch B., Haerting J., Ranft U., et al. Occupational risk factors for renal cell carcinoma: agent-specific results from a case-control study in Germany. MURC Study Group. Multicenter urothelial and renal cancer study. Int J Epidemiol 2000, 29(6):1014-1024.
107. Lynge E., Andersen A., Nilsson R., et al. Risk of cancer and exposure to gasoline vapors. Am J Epidemiol 1997, 145(5):449-458.
108. Mandel J.S., McLaughlin J.K., Schlehofer B., et al. International renal-cell cancer study. IV. Occupation. Int J Cancer 1995, 61(5):601-605.
109. Partanen T., Heikkila P., Hernberg S., et al. Renal cell cancer and occupational exposure to chemical agents. Scand J Work Environ Health 1991, 17(4):231-239.
110. Boffetta P., Jourenkova N., Gustavsson P. Cancer risk from occupational and environmental exposure to polycyclic aromatic hydrocarbons. Cancer Causes Control 1997, 8(3):444-472.
111. Kadamani S., Asal N.R., Nelson R.Y. Occupational hydrocarbon exposure and risk of renal cell carcinoma. Am J Ind Med 1989, 15(2):131-141.
112. Sharpe C.R., Rochon J.E., Adam J.M., et al. Case-control study of hydrocarbon exposures in patients with renal cell carcinoma. CMAJ 1989, 140(11):1309-1318.
113. Cocco P., Hua F., Boffetta P., et al. Mortality of Italian lead smelter workers. Scand J Work Environ Health 1997, 23(1):15-23.
114. Scott C.S., Chiu W.A. Trichloroethylene cancer epidemiology: a consideration of select issues. Environ Health Perspect 2006, 114(9):1471-1478.
115. Kelsh M.A., Alexander D.D., Mink P.J., et al. Occupational trichloroethylene exposure and kidney cancer: a meta-analysis. Epidemiology 2010, 21(1):95-102.
116. Brauch H., Weirich G., Klein B., et al. VHL mutations in renal cell cancer: does occupational exposure to trichloroethylene make a difference?. Toxicol Lett 2004, 151(1):301-310.
117. Axwijk P.H., Kluijt I., de Jong D., et al. Hereditary causes of kidney tumours. Eur J Clin Invest 2010, 40(5):433-439.
118. Choyke P.L., Glenn G.M., Walther M.M., et al. von Hippel-Lindau disease: genetic, clinical, and imaging features. Radiology 1995, 194(3):629-642.
119. Maher E.R. Inherited renal cell carcinoma. Br J Urol 1996, 78(4):542-545.
120. Kim W.Y., Kaelin W.G. Role of VHL gene mutation in human cancer. J Clin Oncol 2004, 22(24):4991-5004.
121. Jacobsen J., Grankvist K., Rasmuson T., et al. Expression of vascular endothelial growth factor protein in human renal cell carcinoma. BJU Int 2004, 93(3):297-302.
122. Van Poppel H., Nilsson S., Algaba F., et al. Precancerous lesions in the kidney. Scand J Urol Nephrol Suppl 2000, (205):136-165.
123. Czene K., Hemminki K. Kidney cancer in the Swedish Family Cancer Database: familial risks and second primary malignancies. Kidney Int 2002, 61(5):1806-1813.
124. Schlehofer B., Pommer W., Mellemgaard A., et al. International renal-cell-cancer study. VI. The role of medical and family history. Int J Cancer 1996, 66(6):723-726.
125. Gago-Dominguez M., Yuan J.M., Castelao J.E., et al. Family history and risk of renal cell carcinoma. Cancer Epidemiol Biomarkers Prev 2001, 10(9):1001-1004.
126. Sweeney C., Farrow D.C., Schwartz S.M., et al. Glutathione S-transferase M1, T1, and P1 polymorphisms as risk factors for renal cell carcinoma: a case-control study. Cancer Epidemiol Biomarkers Prev 2000, 9(4):449-454.
127. Semenza J.C., Ziogas A., Largent J., et al. Gene-environment interactions in renal cell carcinoma. Am J Epidemiol 2001, 153(9):851-859.
128. World Cancer Research Fund, American Institute for Cancer Research Food, nutrition, physical activity, and the prevention of cancer: a global perspective 2007, American Institute for Cancer Research, Washington, DC.