Angiotensin-I-converting enzyme and prolyl endopeptidase inhibitory peptides from natural sources with a focus on marine processing by-products

Food Chemistry

Volumn 129, Issue 2, 2011, Pages 235-244

  Wilson, Julia ^a   Hayes, Maria ^b   Carney, Brian ^a  

^a Atlantic Technological University Sligo   (Ireland)

^b TEAGASC FOOD RESEARCH CENTRE   (Ireland)

Author keywords

Alzheimers; Angiotensin I converting enzyme (ACE 1); FOSHU; Hydrolysis; Hypertension; Mental disease; Prolyl endopeptidase (PEP); Spontaneously hypertensive rats (SHRs)

Indexed keywords

ALZHEIMERS; ANGIOTENSIN I-CONVERTING ENZYME; FOSHU; HYPERTENSION; MENTAL DISEASE; PROLYL ENDOPEPTIDASE; SPONTANEOUSLY HYPERTENSIVE RATS;

ENVIRONMENTAL REGULATIONS; ENZYMES; HYDROLYSIS; SEWAGE; WASTE DISPOSAL;

PEPTIDES;

DIPEPTIDYL CARBOXYPEPTIDASE; NATURAL PRODUCT; PROLYL ENDOPEPTIDASE; PROLYL ENDOPEPTIDASE INHIBITOR;

DERIVATIZATION; FOOD PROCESSING; IN VIVO STUDY; MARINE SPECIES; NONHUMAN; PROTEIN FUNCTION; REVIEW; SEA FOOD;

RATTUS;

EID: 79959969840     PISSN: 03088146     EISSN: 18737072     Source Type: Journal    
DOI: 10.1016/j.foodchem.2011.04.081     Document Type: Review

References (127)

1. T. Akihisa, H. Tokuda, M. Ogata, M. Ukiya, M. Lizuka, and T. Suzuki Cancer chemopreventive effects of poly-unsaturated fatty acids Cancer Letters 2-5 2004 9 13 (Pubitemid 38230133)
2. E.C. Amor, I.M. Villasenor, A. Yasin, and M.I. Choudhary Prolyl endopeptidase inhibitors from Syzygium samarangense (Blume) Merr & L.M. Perry Zeitschrift für Naturforschung 59c 2004 86 92 (Pubitemid 38261250)
3. T. Aoyagi, T. Wada, M. Nagai, F. Kojima, S. Harada, and T. Takeuchi Deficiency of kallikrein-like enzyme activities in cerebral tissue of patients with Alzheimer's disease Cellular and Molecular Life Sciences (CMLS) 46 1990 94 97
4. Y. Ariyoshi Angiotensin-converting enzyme inhibitors derived from food proteins Trends in Food Science and Technology 4 1993 139 144
5. M. Asano, N. Nio, and Y. Ariyoshi Inhibition of prolyl endopeptidase by synthetic peptide fragments of human β-casein Agricultural and Biological Chemistry 55 3 1991 825 828
6. A.B. Atkinson, and J.I.S. Robertson Captopril in the treatment of clinical hypertension and cardiac failure The Lancet 314 1979 836 839 (Pubitemid 10205114)
7. I.M. Bastos, P. Grellier, N.F. Martins, G. Cadavid-Restrepo, M.R. de Souza-Ault, and K. Augustyns Molecular, functional and structural properties of the prolyl oligopeptidase of Trypanosoma cruzi (POP Tc80), which is required for parasite entry into mammalian cells Biochemical Journal 388 2005 29 38 (Pubitemid 40732929)
8. A. Bougatef, N. Nedjar-Arroume, R. Ravallec-Plé, Y. Leroy, D. Guillochon, and A. Barkia Angiotensin I-converting enzyme (ACE) inhibitory activities of sardinelle (Sardinella aurita) by-products protein hydrolysates obtained by treatment with microbial and visceral fish serine proteases Food Chemistry 111 2008 350 356
9. O. Bruyere, K. Pavelka, L.C. Rovati, R. Deroisy, M. Olejarova, and J. Gatterova Glucosamine sulphate reduces osteoarthritis: Evidence from teo 3-year studies Menopause 11 2004 138 143
10. J.P. Burbach, G.L. Kovacs, D. De Wied, J.W. Van Nispen, and H.M. Greven A major metabolite of arginine vasopressin in the brain is a highly potent neuropeptide Science 221 4617 1983 1310 1312 (Pubitemid 13001286)
11. H.G. Byun, and S.K. Kim Purification and characterization of angiotensin I converting enzyme (ACE) inhibitory peptides from Alaska pollack (Theragra chalcogramma) skin Process Biochemistry 36 12 2001 1155 1162
12. S. Chevallier, P. Goeltz, P. Thibault, D. Banville, and J. Gagnon Characterization of a Prolyl Endopeptidase from Flavobacterium Meningosepticum, Complete sequence and localisation of the active-site serine The Journal of Biological Chemistry 267 12 1992 8192 8199
13. C.D. Cinq-Mars, and E.C.Y. Li-Chan Optimizing angiotensin I-converting enzyme inhibitory activity of Pacific hake (Merluccius productus) fillet hydrolysate using response surface methodology and ultrafiltration Journal of Agricultural and Food Chemistry 55 23 2007 9380 9388 (Pubitemid 350205286)
14. D.W. Cushman, and H.S. Cheung Spectrophotometric assay and properties of the angiotensin-converting enzyme of rabbit lung Biochemical Pharmacoogy 20 1971 1637 1648
15. D. De Weid, O. Gaffori, J.M. Van Ree, and W. De Jong Central target for the behavioural effects of vasopressin neuropeptides Nature 308 1984 276 278 (Pubitemid 14132031)
16. P.V. Dicpinigaitis Angiotensin-converting enzyme inhibitor-induced cough, ACCP evidence-based clinical practice guidelines Chest 129 2006 169S 173S (Pubitemid 43265218)
17. D. Duprez, P. Van Helshoecht, W. Van den Eynd, and M. Leeman Prevalence of hypertension in the adult population of Belgium: Report of a worksite study: Attention hypertension Journal of Human Hypertension 16 2002 47 52 (Pubitemid 34134093)
18. K. Erdmann, B.W.Y. Cheung, and H. Schröder The possible roles of food-derived bioactive peptides in reducing the risk of cardiovascular disease Journal of Nutritional Biochemistry 19 2008 643 654
19. W. Fan, Y. Tezuka, K. Komatsu, T. Namba, and S. Kadota Polyl endopeptidase inhibitors from the underground part of Rhodiola sacra S.H. Fu Biological & Pharmaceutical Bulletin 22 1999 157 161 (Pubitemid 29114032)
20. W. Fan, Y. Tezuka, K.M. Ni, and S. Kadota Prolyl endopeptidase inhibitors from the underground part of Rhodiola sachalinensis Chem Pharm Bull (Tokoyo) 49 2001 369 401
21. FAO (2008). State of World Fisheries and Aquaculture (SOFIA) Report. Food and Agriculture Organization of the United Nations, Rome, Italy. Available from < http://www.fao.org/docrep/fao/011/i0250e/i0250e01.pdf >.
22. H. Fujita, H. Usui, K. Kurahashi, and M. Yoshikawa Isolation and characterization of ovokinin, a bradykinin B1 agonist peptide derived from ovalbumin Peptides 16 5 1995 785 790
23. H. Fujita, and M. Yoshikawa LKPNM: A prodrug-type ACE-inhibitory peptide derived from fish protein Immunopharmacology 44 1999 123 127
24. A. Fukunari, A. Kato, Y. Sakai, T. Yoshimoto, S. Ishiura, and K. Suzuki Colocalization of prolyl endopeptidase and amyloid β-peptide in brains of senescence-accelerated mouse Neuroscience Letters 176 1994 201 204
25. M.L. Gardner Gastrointestinal absorption of intact proteins Annual Review of Nutrition 8 1988 329 350 (Pubitemid 19136330)
26. M. Gobbetti, F. Minervini, and C.G. Rizzello Angiotensin I-converting enzyme-inhibitory and antimicrobial bioactive peptides International Journal of Dairy Technology 57 2004 173 188 (Pubitemid 38667883)
27. M. Gobbetti, L. Stepaniak, M. De Angelis, A. Corsetti, and R. Di Cagno Latent bioactive peptides in milk proteins: Proteolytic activation and significance in Dairy Processing Critical Reviews in Food Science and Nutrition 42 3 2002 223 239
28. Guerard, F.; Chabeaud, A.; Laroque, D. (2008). Processing of proteainaceaous solid by-products by enzymatic hydrolysis. In J.-P. Berge (Ed.), Transworld research network (pp.101-116). Kerala, India.
29. F. Guerard, N. Decourcelle, C. Sabourin, C. Floch-Laizet, L. Le Grel, and P. Le Floch Recent developments of marine ingredients for food and nutraceutical applications: A review Journal Scientific Halleutique Aqua 2 2010 21 27
30. R. Hartmann, and H. Meisel Food-derived peptides with biological activity: From research to food applications Current Opinion in Biotechnology 18 2007 163 169 (Pubitemid 46575225)
31. M. Hayes, C. Stanton, H. Slattery, O. O'Sullivan, C. Hill, and G.F. Fitzgerald Casein fermentate of Lactobacillus animalis DPC6134 contains a range of novel propeptide angiotensin-converting enzyme inhibitors Applied and Environmental Microbiology 73 14 2007 4658 4667 (Pubitemid 47122611)
32. H.L. He, X.L. Chen, H. Wu, C.Y. Sun, Y.Z. Zhang, and B.C. Zhou High throughput and rapid screening of marine protein hydrolysates enriched in peptides with angiotensin-I-converting enzyme inhibitory activity by capillary electrophoresis Bioresource Technology 98 2007 3499 3505 (Pubitemid 47333129)
33. K. Hermansen Diet, blood pressure and hypertension British Journal of Nutrition 83 S1 2000 113 119
34. M.M. Husain, and C.B. Nemeroff Neuropeptides and Alzheimer's disease Journal of the American Geriatric Society 38 8 1990 918 925 (Pubitemid 20267754)
35. C. Ichai, N. Chevallier, P. Delaere, P. Dournaud, J. Epelbaum, and J.J. Hauw Influence of region specific alterations of neuropeptidase content on the catabolic fates of neuropeptides in Alzheimer's disease Journal of Neurochemistry 62 1994 645 655 (Pubitemid 24041334)
36. T. Ichimura, J. Hu, D.Q. Aita, and S. Maruyama Angiotensin I-converting enzyme inhibitory activity and insulin secretion stimulative activity of fermented fish sauce Journal of Bioscience and Bioengineering 96 5 2003 496 499 (Pubitemid 37533395)
37. J. Irazusta, G. Larrinaga, J. Gonzalez-Maeso, J. Gil, J.J. Meana, and L. Casis Distribution of prolyl endopeptidase activities in rat and human brain Neurochemistry International 40 2002 337 345 (Pubitemid 34131608)
38. K. Itou, and Y. Akahane Antihypertensive effect of heshiko, a fermented mackerel product, on spontaneously hypertensive rats Fisheries Science 70 2004 1121 1129 (Pubitemid 40033427)
39. J. Jae-Young, P.-J. Park, H.-G. Byun, W.-K. Jung, and S.-K. Kim Angiotensin I converting enzyme (ACE) inhibitory peptide derived from the sauce of fermented blue mussel Mytilus edulis Bioresource Technology 96 2005 1624 1629 (Pubitemid 40840711)
40. Jarho, E. (2007). Synthesis, structure-activity relationships and physico-chemical properties of novel prolyl oligopeptidase inhibitors. Doctoral dissertation presented to the Faculty of Pharmacy of the University of Kuopio, Department of Pharmaceutical Chemistry, University of Kuopio, Finland.
41. J.Y. Je, E.K. Kim, C.B. Ahn, S.H. Moon, B.T. Jeon, and B.Y. Kim Sulfated chitooligosaccharides as propyl endopeptidase inhibitors International Journal of Biological Macromolecules 41 2007 529 533
42. J.Y. Je, J.Y. Park, W.K. Jung, P.J. Park, and S.K. Kim Isolation of angiotensin-1 converting enzyme (ACE) inhibitor from fermented oyster sauce, Crassostrea gigas Food Chemistry 90 2005 809 814
43. V.K. Jimsheena, and L.R. Gowda Colorimetric, high-throughput assay for screening Angiotensin I-converting enzyme inhibitors Analytical Chemistry 81 2009 9388 9394
44. S. Kalwant, and A.G. Porter Purification and characterization of human brain prolyl endopeptidase Biochemistry Journal 276 1991 237 244
45. P.M. Kearney, M. Whelton, K. Reynolds, P. Muntner, and J. He Global burden of hypertension: Analysis of worldwide data The Lancet 365 2005 217 223 (Pubitemid 40138015)
46. D.S. Kelley Modulation of human immune and inflammatory responses by dietary fatty acids Nutrition 17 2001 669 673 (Pubitemid 32633805)
47. F. Khanom, H. Kayahara, and K. Tadasa Superoxide-scavenging and prolyl endopeptidase inhibitory activities of Bangladeshi indigenous medicinal plants Bioscience, Biotechnology, and Biochemistry 64 2000 837 840
48. J.H. Kim, S.I. Kim, and K.S. Song Prolyl endopeptidase inhibitors from Green Tea Archives of Pharmacal Research 24 4 2001 292 296
49. S.K. Kim, and E. Mendis Bioactive compounds from marine processing byproducts - A review Food Research International 39 4 2006 383 393 (Pubitemid 43233723)
50. D.D. Kitts, and K. Weiler Bioactive proteins and peptides from food sources. Applications of bioprocesses used in isolation and recovery Current Pharmaceutical Design 9 2003 1309 1323 (Pubitemid 36592139)
51. W. Kobayashi, T. Miyase, M. Sano, K. Umehara, T. Warashina, and H. Noguchi Prolyl endopeptidase inhibitors from the roots of Lindera strychnifolia F. Vill Biological and Pharmaceutical Bulletin 25 8 2002 1049 1052 (Pubitemid 39663231)
52. Y. Kohama, S. Matsumoto, H. Oka, T. Teramoto, M. Okabe, and T. Mimura Isolation of angiotensin-converting enzyme inhibitor from tuna muscle Biochemical and Biophysical Research Communication 155 1 1988 332 337
53. T. Kuwabara Characterisation of a prolyl endopeptidase from spinach thylakoids FEBS Letters 300 2 1992 127 130
54. T. Larsen, S.H. Thilsted, K. Kongsbak, and M. Hansen Whole small fish as a rich calcium source British Journal of Nutrition 83 2000 191 196 (Pubitemid 30093052)
55. J.H. Lee, S.Y. Lee, K.S. Lee, H.J. Jang, K.H. Lee, and T.R. Hahn Prolyl endopeptidase inhibitors from the leaves of Ginkgo biloba Planta Medica 70 12 2004 1228 1230
56. A.D. Lopez, and C.C. Murray The global burden of disease, 1990-2020 Nature Medicine 4 1998 1241 1243 (Pubitemid 28512100)
57. M. Maes, F. Goossens, A. Lin, I. De Meester, A. Van Gastel, and S. Scharpe Effects of psychological stress on serum prolyl endopeptidase and dipeptidyl peptidase IV activity in humans: Higher serum prolyl endopeptidase activity is related to stress-induced anxiety Psychoneuroendocrinology 23 1998 485 495 (Pubitemid 28459567)
58. M. Maes, F. Goossens, S. Scharpé, J. Calabrese, R. Desnyder, and H.Y. Meltzer Alteration in plasma prolyl endopeptidase activity in depression, mania, and schizophrenia: Effect of antidepressants, mood stabilizers, and antipsychotic drugs Psychiatry Research 58 1995 217 225
59. M. Maes, A.H. Lin, S. Bonaccoroso, F. Goossens, A.V. Gastel, and R. Pioli Higher serum prolylendopeptidase activity in patients with post-traumatic stress disorder Journal of Affective Disorders 53 1999 27 34 (Pubitemid 29227350)
60. M. Maes, P. Monteleone, R. Bencivenga, F. Goossens, M. Maj, and D. van West Lower serum activity of prolyl endopeptidase in anorexia and bulimia nervosa Psychoneuroendocrinology 26 2001 17 26
61. S. Maruyama, S. Miyoshi, T. Osa, and H. Tanaka Prolyl endopeptidase inhibitory activity of peptides in the repeated sequence of various Proline-rich proteins Journal of Fermentation and Bioengineering 74 3 1992 145 148
62. O. Masuda, Y. Nakamura, and T. Takano Antihypertensive peptides are present in aorta after oral administration of sour milk containing these peptides to spontaneously hypertensive rats Journal of Nutrition 126 1996 3063 3068 (Pubitemid 27023881)
63. C. Matar, J. Amiot, L. Savoie, and J. Goulet The effect of milk fermentation by Lactobacillus helveticus on the release of peptides during in vitro digestion Journal of Dairy Science 79 6 1996 971 979 (Pubitemid 126429132)
64. N. Matoba, H. Usui, H. Fujita, and M. Yoshikawa A novel anti-hypertensive peptide derived from ovalbumin induces nitric oxide-mediated vasorelaxation in an isolated SHR mesenteric artery FEBS Letters 452 1999 181 184 (Pubitemid 29301740)
65. H. Matsufuji, T. Matsui, E. Seki, K. Osajima, M. Nakashima, and Y. Osajima Angiotensin I-converting enzyme inhibitory peptides in an alkaline protease hydrolyzate derived from sardine muscle Biocience Biotechnology and Biochemistry 58 1994 2244 2245
66. H. Meisel Biochemical properties of regulatory peptides derived from milk proteins Biopolymers 43 1997 119 128 (Pubitemid 27291390)
67. H. Meisel Multifunctional peptides encrypted in milk proteins BioFactors 21 2004 55 61 (Pubitemid 40921826)
68. H. Meisel, D.J. Walsh, B.A. Murray, and R.J. FitzGerald ACE inhibitory peptides Y. Mine, F. Shahidi, Nutraceutical proteins and peptides in health and disease. An overview 2006 CRC Press, Taylor and Francis Group New York 269 315
69. M. Miguel, M.M. Contreras, I. Recio, and A. Aleixandre ACE-inhibitory and antihypertensive properties of a bovine casein hydrolysate Food Chemistry 112 2009 211 214
70. F. Minervini, F. Algaron, C.G. Rizzello, P.F. Fox, V. Monnet, and M. Gobbetti Angiotensin I-converting-enzyme-inhibitory and antibacterial peptides from Lactobacillus helveticus PR4 proteinase-hydrolyzed caseins of milk from six species Applied and Environmental Microbiology 69 2003 5297 5305 (Pubitemid 37150754)
71. S. Miyoshi, T. Kaneko, H. Ishikawa, H. Tanaka, and S. Maruyama Production of bioactive peptides from corn endosperm proteins by some proteases Annals of the New York Academy of Sciences 750 1995 429 431
72. S. Mizuno, K. Matsuura, T. Gotou, S. Nishimura, O. Kajimoto, and M. Yabune Antihypertensive effect of casein hydrolysate in a placebo-controlled study in subjects with high-normal blood pressure and mild hypertension British Journal of Nutrition 94 1 2005 84 91 (Pubitemid 41357814)
73. S. Mizuno, S. Nishimura, K. Matsuura, T. Goyou, and N. Yamamoto Release of short and proline rich antihypertensive peptides from casein hydrolysates with an Aspergillus oryzae protease Journal of Dairy Science 87 2004 3183 3188 (Pubitemid 39408453)
74. N. Momeni, B.M. Nordström, V. Horstmann, H. Avarseji, and B.V. Sivberg Alterations of prolyl endopeptidase activity in the plasma of children with autistic spectrum disorders BMC Psychiatry 5 2005 27
75. P. Morain, P. Lestage, G. De Nanteuil, R. Jochemsen, J.L. Robin, and D. Guez S 17092: A prolyl endopeptidase inhibitor as a potential therapeutic drug for memory impairment. Preclinical and clinical studies CNS Drug Reviews 8 1 2002 31 52 (Pubitemid 34651314)
76. A. Moriyama, M. Nakanishi, and M. Sasaki Porcine muscle prolyl endopeptidase and its endogenous substrates Journal of Biochemistry 104 1 1988 112 117
77. Y. Nakamura, N. Yamamoto, K. Sakai, Y. Okuba, S. Yamazaki, and T. Takano Purification and characterization of angiotensin I-converting enzyme inhibitors from sour milk Journal of Dairy Science 78 4 1995 777 783
78. T. Ohmori, T. Nakagami, H. Tanaka, and S. Maruyama Isolation of prolyl-endopeptidase-inhibiting peptides from bovine brain Biochemical and Biophysical Research Communications 202 2 1994 809 815 (Pubitemid 24259286)
79. S. Ono, M. Hosokawa, K. Miyashita, and K. Takahashi Inhibition properties of dipeptides from salmon muscle hydrolysate on angiotensin I-converting enzyme International Journal of Food Science and Technology 41 4 2005 383 386
80. T. Pailin, D.H. Kang, K. Schmidt, and D.Y.C. Fung Detection of extracellular bound proteinase in EPS-producing lactic acid bacteria cultures on skim milk agar Letters in Applied Microbiology 33 2001 45 49 (Pubitemid 32625732)
81. Y.S. Park, H.J. Jang, K.H. Lee, T.R. Hahn, and Y.S. Paik Prolyl endopeptidase inhibitory activity of unsaturated fatty acids Journal of Agricultural and Food Chemistry 54 4 2006 1238 1242
82. Pfeiffer, N. (2003). Disposal and re-utilisation of fish and fish processing waste (including aquaculture waste). NDP Marine RTDI Desk Study series DK/01/003.2003 ISSN; 16495063, 3-6. < http://www.marine.ie/marinertdi >.
83. A. Pihlanto, S. Akkanen, and H.J. Korhonen ACE-inhibitory and antioxidant properties of potato (Solanum tuberosum) Food Chemistry 109 2008 104 112
84. M.A. Pozo-Bayón, J.M. Alcaíde, M.C. Polo, and E. Pueyo Angiotensin I-converting enzyme inhibitory compounds in white and red wines Food Chemistry 100 2007 43 47
85. K. Prak, Y. Maruyama, N. Maruyama, and S. Utsumi Design of genetically modified soybean proglycinin A1aB1b with multiple copies of bioactive peptide sequences Peptides 27 2006 1179 1186 (Pubitemid 43767001)
86. D. Rennex, B.A. Hemmings, J. Hofsteenge, and S.R. Stone CDNA cloning of porcine brain prolyl endopeptidase and identification of the active- site seryl residue Biochemistry 30 1991 2159 2203
87. R. Ringseis, B. Matthes, V. Lehmann, K. Becker, R. Schops, and R. Ulbrich-Hofmann Peptides and hydrolysates from casein and soy protein modulate the release of vasoactive substances from human aortic endothelial cells Biochimica et Biophysica Acta 1721 2005 89 97 (Pubitemid 40093516)
88. J.F. Riordan Angiotensin-1-converting enzyme and its relatives Genome Biology 4 2003 225
89. P.R. Roberts, J.D. Burney, K.W. Black, and G.P. Zaloga Effect of chain length on absorption of biologically active peptides from the gastrointestinal tract Digestion 60 1999 332 337 (Pubitemid 29292229)
90. T. Rokka Release of bioactive peptides by enzymatic proteolysis of Lactobacillus GG fermented UHT milk Milchwissenschaft 52 12 1997 675 677 (Pubitemid 127371911)
91. M.N. Rossor, P.C. Emson, D. Dawbarn, C.Q. Mountjoy, and M. Roth Neuropeptides and dementia Progress in Brain Research 66 1986 143 159
92. M.K. Roy, Y. Watanabe, and Y. Tamai Yeast protease B-digested skimmed milk inhibits angiotensin-I-converting-enzyme activity Biotechnology and Applied Biochemistry 31 2000 95 100 (Pubitemid 30197871)
93. S. Roβner, I. Schulz, U. Zeitschel, R. Schliebs, V. Bigl, and H.U. Demuth Brain prolyl endopeptidase expression in aging, APP transgenic mice and Alzheimer's disease Neurochemical Research 30 2005 695 702 (Pubitemid 41413928)
94. J.H. Rupnow, W.L. Taylor, and J.E. Dixon Purification and characterization of a thyrotropin-releasing hormone deamidase from rat brain Biochemistry 18 1979 1206 1212 (Pubitemid 9178167)
95. A. Saiga, T. Okumura, T. Makihara, S. Katsuda, M. Toshikazu, and R. Yamada Action mechanism of an angiotensin I-converting enzyme inhibitory peptide derived from chicken breast muscle Journal of Agricultural Food Chemistry 53 2006 942 945 (Pubitemid 43274135)
96. Y. Saito, S. Ohura, A. Kawato, and K. Suiginami Prolyl endopeptidase inhibitors in sake and its byproducts Journal of Agricultural Food Chemistry 45 1997 720 724 (Pubitemid 127483695)
97. M. Sato, T. Hosokawa, T. Yamaguchi, T. Nakano, K. Muramoto, and T. Kahara Angiotensin I-converting enzyme inhibitory peptides derived from Wakame (Undaria pinnatifida) and their antihypertensive effect in spontaneously hypertensive rats Journal of Agricultural Food Chemistry 50 2002 6245 6252 (Pubitemid 35155365)
98. A.K.M.A. Sattar, N. Yamamoto, T. Yoshimoto, and D. Tsuru Purification and characterization of an extracellular prolyl endopeptidase from Agaricus bispoms Journal of Biochemistry (Tokyo) 107 2 1990 256 263
99. I.C. Sheih, T.J. Fang, and T.K. Wu Isolation and characterisation of a novel angiotensin I-converting enzyme (ACE) inhibitory peptide from the algae protein waste Food Chemistry 115 2009 279 284
100. S.V. Silva, and F.X. Malcata Caseins as source of bioactive peptides International Dairy Journal 15 2005 1 15 (Pubitemid 39527112)
101. J.S. Silvestre, C. Heymes, A. Oubénaïssa, V. Robert, B. Aupetit-Faisant, and A. Carayon Activation of cardiac aldosterone production in rat myocardial infarction: Effect of angiotensin II receptor blockade and role in cardiac fibrosis Circulation 99 1999 2694 2701 (Pubitemid 29237459)
102. R. Sorensen, E. Kildal, L. Stepaniak, A.H. Pripp, and T. Sorhaug Screening for peptides from fish and cheese inhibitory to prolyl endopeptidase Nahrung /Food 48 1 2004 53 56 (Pubitemid 38368287)
103. P.C. Srinivosa, and R.N. Tharanatham Chitin/chitosan-safe, ecofriendly packaging materials with multiple potential uses Food Reviews International 23 1 2007 53 72
104. K. Suetsuna Isolation and characterization of angiotensin I converting enzyme inhibitor dipeptides derived from Allium sativum L. (garlic) The Journal of Nutritional Biochemistry 9 1998 415 419 (Pubitemid 28561541)
105. K. Suetsuna Identification of antihypertensive peptides from peptic digest of the short-necked clam Tapes philippinarum and the pearl oyster Pinctada fucata martensii Fisheries Science 68 2002 233 235 (Pubitemid 34209441)
106. T. Takano Milk derived peptides and hypertension reduction International Dairy Journal 8 5 1998 375 381 (Pubitemid 28504136)
107. Y. Tezuka, W. Fan, R. Kasimu, and S.H. Kadota Screening of crude drug extracts for prolyl endopeptidase inhibitory activity Phytomedicine 6 1999 197 203 (Pubitemid 129632916)
108. A.E. Theodore, and H.G. Kristinsson Angiotensin converting enzyme inhibition of fish protein hydrolysates prepared from alkaline-aided channel catfish protein isolate Journal of the Science of Food and Agriculture 87 2007 2353 2357 (Pubitemid 47346184)
109. D.J.C. Van der Berg, A. Smiths, B. Pot, and A.M. Ledeboer Isolation, screening and identification of lactic acid bacteria from traditional food fermentation processes and culture collections Food Biotechnology 7 3 1993 189 205
110. V. Vermeirssen, J. van Camp, and W. Verstraete Bioavailability of angiotensin-I-converting enzyme inhibitory peptides British Journal of Nutrition 92 2004 357 366 (Pubitemid 40277058)
111. R. Walter, H. Shlank, J.D. Glass, I.L. Schwartz, and T.D. Kerenyi Leucylglycinamide released from oxytocin by human uterine enzyme Science 173 1971 827 829
112. R. Walter, W.H. Simmons, and T. Yoshimoto Proline specific endo-and exopeptidases Molecular and Cellular Biochemistry 30 1980 111 127
113. Y.K. Wang, H.L. He, X.L. Chen, C.Y. Sun, Y.Z. Zhang, and B.C. Zhou Production of novel angiotensin I-converting enzyme inibitory peptides by fermentation of marine shrimp Acetes chinensis with Lactobacillus fermentum SM 605 Applied Microbiology and Biotechnology 79 5 2008 785 791
114. J. Wang, J. Hu, J. Cui, X. Bai, Y. Du, and Y. Miyaguchi Purification and identification of an ACE inhibitory peptide from oyster proteins hydrolysate and the antihypertensive effect of hydrolysate in spontaneously hypertensive rats Food Chemistry 111 2008 302 308
115. K.E. Webb Intestinal absorption of protein hydrolysis products: A review Journal of Animal Science 68 1990 3011 3022
116. W.R. Welches, K.B. Brosnihan, and C.M. Ferrario A comparison of the properties and enzymatic activities of three Angiotensin processing enzymes: Angiotensin converting enzyme, prolyl endopeptidase and neutral endopeptidase 24.11 Life Sciences 52 1993 1461 1480
117. R.S.B. Williams Prolyl oligopeptidase and bipolar disorder Clinical Neuroscience Research 4 2004 233 242 (Pubitemid 40197846)
118. J. Wu, R.E. Aluko, and A.D. Muir Improved method for direct high-performance liquid chromatography assay of angiotensin-converting enzyme-catalyzed reactions Journal of Chromatography 950 2002 125 130 (Pubitemid 34188550)
119. H. Wu, H.L. He, X.L. Chen, C.Y. Sun, Y.Z. Zhang, and B.C. Zhou Purification and identification of novel angiotensin-I-converting enzyme inhibitory peptides from shark meat hydrolysate Process Biochemistry 43 2008 457 461
120. T. Yanai, Y. Suzuki, and M. Sato Prolyl endopeptidase inhibitory peptides in wine Bioscience Biotechnology and Biochemistry 67 2 2003 380 382 (Pubitemid 39251995)
121. H.Y.T. Yang, E.O. Erdos, and Y. Levin Characterization of a di-peptide hydrolase (kininase II: Angiotensin-I- converting enzyme The Journal of Pharmacology and Experimental Therapeutics 177 1971 291 300
122. K. Yokoyama, H. Chiba, and M. Yoshikawa Peptide inhibitors for angiotensin I-converting enzyme from thermolysin digest of dried bonito Bioscience Biotechnology and Biochemistry 56 10 1992 1541 1545
123. M. Yoshikawa, H. Fujita, N. Matoba, Y. Takenaka, T. Yamamoto, and R. Yamauchi Bioactive peptides derived from food proteins preventing lifestyle-related diseases BioFactors 12 1-4 2000 143 146 (Pubitemid 32107398)
124. T. Yoshimoto, T. Nishimura, T. Kita, and D. Tsuru Post-proline cleaving enzyme (prolyl endoeptidase) from bovine brain Journal of Biochemistry (Tokyo) 94 1983 1179 1190
125. T. Yoshimoto, K. Ogita, R. Walter, M. Kodia, and D. Tsuru Post-proline cleaving enzyme, synthesis of a new fluorogenic substrate and distribution of the endopeptidase in rat tissues and body fluids of man Biochimica et Biophysica Acta 569 1979 184 192 (Pubitemid 9237879)
126. T. Yoshimoto, A.K.M.A. Sattar, W. Hirose, and D. Tsuru Studies on prolyl endopeptidase from shakashimeji (Lyophyllum cinerascens): Purification and enzymatic properties The Journal of Biochemistry (Tokyo) 104 4 1988 622 627
127. T. Yoshimoto, W.H. Simmons, T. Kita, and D. Tsuru Post-proline cleaving enzyme from lamb brain The Journal of Biochemistry (Tokyo) 90 1981 325 334