Molecular, functional and structural properties of the prolyl oligopeptidase of Trypanosoma cruzi (POP Tc80), which is required for parasite entry into mammalian cells

Biochemical Journal

Volumn 388, Issue 1, 2005, Pages 29-38

  Bastos, Izabela M D ^a   Grellier, Philippe ^b   Martins, Natalia F ^c   Cadavid Restrepo, Gloria ^a   De Souza Ault, Marian R ^a   Augustyns, Koen ^d   Teixeira, Antonio R L ^a   Schrével, Joseph ^b   Maigret, Bernard ^e   Da Silveira, José F ^f   Santana, Jaime M ^a  

^a UNIVERSITY OF BRASILIA   (Brazil)

^b MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^c EMBRAPA RECURSOS GENÉTICOS E BIOTECNOLOGIA   (Brazil)

^d UNIVERSITY OF ANTWERP   (Belgium)

^e UNIVERSITÉ DE LORRAINE   (France)

^f FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Mammalian cell; Prolyl oligopeptidase; Structural modelling; Tc80 proteinase; Trypanosoma cruzi; Trypomastigote

Indexed keywords

CATALYTIC SITES; CELL INVASION; PARASITES; PROLYL OLIGOPEPTIDASE OF TRYPANOSOMA CRUZI (POP TC80);

AMINO ACIDS; CATALYSIS; CELL CULTURE; ENZYME INHIBITION; GENES; HYDROLYSIS; MOLECULAR STRUCTURE;

ENZYMES;

COLLAGEN; DOCKING PROTEIN; HYDROLASE; PROLYL ENDOPEPTIDASE;

AMINO ACID SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL INVASION; CHROMOSOME MAP; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; GENOME; HYDROLYSIS; MAMMAL CELL; MOLECULAR CLONING; NONHUMAN; NUCLEOTIDE SEQUENCE; PATHOGENICITY; PHAGOCYTOSIS; PRIORITY JOURNAL; SOUTHERN BLOTTING; TRYPANOSOMA CRUZI;

AMINO ACID SEQUENCE; ANIMALS; CATALYTIC DOMAIN; CELL ADHESION; CELL LINE; ENZYME INHIBITORS; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, TERTIARY; SEQUENCE HOMOLOGY, AMINO ACID; SERINE ENDOPEPTIDASES; TRYPANOSOMA CRUZI;

MAMMALIA; SUIDAE; TRYPANOSOMA; TRYPANOSOMA CRUZI;

EID: 21144452677     PISSN: 02646021     EISSN: None     Source Type: Journal    
DOI: 10.1042/BJ20041049     Document Type: Article

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