Structural basis for the β-adrenergic receptor subtype selectivity of the representative agonists and antagonists

Journal of Chemical Information and Modeling

Volumn 51, Issue 6, 2011, Pages 1405-1422

  Roy, Kuldeep K ^a   Saxena, Anil K ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

[No Author keywords available]

Indexed keywords

NUTRITION;

BETA ADRENERGIC RECEPTOR; BINDING AFFINITIES; BINDING FREE ENERGY; DIRECT INTERACTIONS; GENERALIZED BORN SURFACE AREAS (GBSA); STRUCTURAL REQUIREMENTS; THERAPEUTIC AGENTS; THREE-DIMENSIONAL STRUCTURE;

BINDING ENERGY;

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; LIGAND; PROTEIN SUBUNIT; RHODOPSIN;

AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DRUG ANTAGONISM; DRUG DESIGN; DRUG POTENTIATION; ENZYME SPECIFICITY; EXTRACELLULAR SPACE; HUMAN; INTRACELLULAR SPACE; METABOLISM; MOLECULAR DYNAMICS; MOLECULAR GENETICS; PROTEIN SECONDARY STRUCTURE; THERMODYNAMICS;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; AMINO ACID SEQUENCE; DRUG DESIGN; EXTRACELLULAR SPACE; HUMANS; INTRACELLULAR SPACE; LIGANDS; MOLECULAR DYNAMICS SIMULATION; MOLECULAR SEQUENCE DATA; PROTEIN STRUCTURE, SECONDARY; PROTEIN SUBUNITS; RECEPTORS, ADRENERGIC, BETA; RHODOPSIN; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 79959737912     PISSN: 15499596     EISSN: 1549960X     Source Type: Journal    
DOI: 10.1021/ci2000874     Document Type: Article

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