-
1
-
-
0034784920
-
Rhodopsin: structural basis of molecular physiology
-
Menon S.T., Han M., and Sakmar T.P. Rhodopsin: structural basis of molecular physiology. Physiol. Rev. 81 (2001) 1659-1688
-
(2001)
Physiol. Rev.
, vol.81
, pp. 1659-1688
-
-
Menon, S.T.1
Han, M.2
Sakmar, T.P.3
-
2
-
-
5044235587
-
Electron crystallography reveals the structure of Metarhodopsin I
-
Ruprecht J., Mielke T., Vogel R., Villa C., and Schertler G.F.X. Electron crystallography reveals the structure of Metarhodopsin I. EMBO J. 23 (2004) 3609-3620
-
(2004)
EMBO J.
, vol.23
, pp. 3609-3620
-
-
Ruprecht, J.1
Mielke, T.2
Vogel, R.3
Villa, C.4
Schertler, G.F.X.5
-
3
-
-
0029778268
-
Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F
-
Sheikh S.P., Zvyaga T.A., Lichtarge O., Sakmar T.P., and Bourne H.R. Rhodopsin activation blocked by metal-ion-binding sites linking transmembrane helices C and F. Nature 383 (1996) 347-350
-
(1996)
Nature
, vol.383
, pp. 347-350
-
-
Sheikh, S.P.1
Zvyaga, T.A.2
Lichtarge, O.3
Sakmar, T.P.4
Bourne, H.R.5
-
4
-
-
0029907599
-
Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin
-
Farrens D.L., Altenbach C., Yang K., Hubbell W.L., and Khorana H.G. Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. Science 274 (1996) 768-770
-
(1996)
Science
, vol.274
, pp. 768-770
-
-
Farrens, D.L.1
Altenbach, C.2
Yang, K.3
Hubbell, W.L.4
Khorana, H.G.5
-
5
-
-
3142773613
-
Rhodopsin activation exposes a key hydrophobic binding site for the transducin α-subunit C terminus
-
Janz J.M., and Farrens D.L. Rhodopsin activation exposes a key hydrophobic binding site for the transducin α-subunit C terminus. J. Biol. Chem. 279 (2004) 29767-29773
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 29767-29773
-
-
Janz, J.M.1
Farrens, D.L.2
-
6
-
-
0030975286
-
Transducin-α C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin
-
Acharya S., Saad Y., and Karnik S.S. Transducin-α C-terminal peptide binding site consists of C-D and E-F loops of rhodopsin. J. Biol. Chem. 272 (1997) 6519-6524
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6519-6524
-
-
Acharya, S.1
Saad, Y.2
Karnik, S.S.3
-
8
-
-
0032562699
-
Functional microdomains in G-protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor
-
Ballesteros J.A., Kitanovic S., Guarnieri F., Davies P., Fromme B.J., Konvicka K., et al. Functional microdomains in G-protein-coupled receptors. The conserved arginine-cage motif in the gonadotropin-releasing hormone receptor. J. Biol. Chem. 273 (1998) 10445-10453
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 10445-10453
-
-
Ballesteros, J.A.1
Kitanovic, S.2
Guarnieri, F.3
Davies, P.4
Fromme, B.J.5
Konvicka, K.6
-
9
-
-
0028061193
-
A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin
-
Arnis S., Fahmy K., Hofmann K.P., and Sakmar T.P. A conserved carboxylic acid group mediates light-dependent proton uptake and signaling by rhodopsin. J. Biol. Chem. 269 (1994) 23879-23881
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 23879-23881
-
-
Arnis, S.1
Fahmy, K.2
Hofmann, K.P.3
Sakmar, T.P.4
-
10
-
-
0027270898
-
Regulation of the rhodopsin-transducin interaction by a highly conserved carboxylic acid group
-
Fahmy K., and Sakmar T.P. Regulation of the rhodopsin-transducin interaction by a highly conserved carboxylic acid group. Biochemistry 32 (1993) 7229-7236
-
(1993)
Biochemistry
, vol.32
, pp. 7229-7236
-
-
Fahmy, K.1
Sakmar, T.P.2
-
11
-
-
6344248639
-
Structure of bovine rhodopsin in a trigonal crystal form
-
Li J., Edwards P.C., Burghammer M., Villa C., and Schertler G.F.X. Structure of bovine rhodopsin in a trigonal crystal form. J. Mol. Biol. 343 (2004) 1409-1438
-
(2004)
J. Mol. Biol.
, vol.343
, pp. 1409-1438
-
-
Li, J.1
Edwards, P.C.2
Burghammer, M.3
Villa, C.4
Schertler, G.F.X.5
-
12
-
-
36248970132
-
Crystal structure of the human beta-2 adrenergic G-protein-coupled receptor
-
Rasmussen S.G., Choi H.J., Rosenbaum D.M., Kobilka T.S., Thian F.S., Edwards P.C., et al. Crystal structure of the human beta-2 adrenergic G-protein-coupled receptor. Nature 450 (2007) 383-387
-
(2007)
Nature
, vol.450
, pp. 383-387
-
-
Rasmussen, S.G.1
Choi, H.J.2
Rosenbaum, D.M.3
Kobilka, T.S.4
Thian, F.S.5
Edwards, P.C.6
-
13
-
-
0034604451
-
Crystal structure of rhodopsin: a G protein-coupled receptor
-
Palczewski K., Kumasaka T., Hori T., Behnke C.A., Motoshima H., Fox B.A., et al. Crystal structure of rhodopsin: a G protein-coupled receptor. Science 289 (2000) 739-745
-
(2000)
Science
, vol.289
, pp. 739-745
-
-
Palczewski, K.1
Kumasaka, T.2
Hori, T.3
Behnke, C.A.4
Motoshima, H.5
Fox, B.A.6
-
14
-
-
0037197848
-
Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography
-
Okada T., Fujiyoshi Y., Silow M., Navarro J., Landau E.M., and Shichida Y. Functional role of internal water molecules in rhodopsin revealed by X-ray crystallography. Proc. Natl. Acad. Sci. USA 99 (2002) 5982-5987
-
(2002)
Proc. Natl. Acad. Sci. USA
, vol.99
, pp. 5982-5987
-
-
Okada, T.1
Fujiyoshi, Y.2
Silow, M.3
Navarro, J.4
Landau, E.M.5
Shichida, Y.6
-
15
-
-
0035800850
-
Activation of the β2 adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6
-
Ballesteros J.A., Jensen A.D., Liapakis G., Rasmussen S.G., Shi L., Gether U., and Javitch J.A. Activation of the β2 adrenergic receptor involves disruption of an ionic lock between the cytoplasmic ends of transmembrane segments 3 and 6. J. Biol. Chem. 276 (2001) 29171-29177
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 29171-29177
-
-
Ballesteros, J.A.1
Jensen, A.D.2
Liapakis, G.3
Rasmussen, S.G.4
Shi, L.5
Gether, U.6
Javitch, J.A.7
-
16
-
-
0036239236
-
Mutagenesis and modelling of the α1b adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation
-
Greasley P.J., Fanelli F., Rossier O., Abuin L., and Cotecchia S. Mutagenesis and modelling of the α1b adrenergic receptor highlight the role of the helix 3/helix 6 interface in receptor activation. Mol. Pharmacol. 61 (2002) 1025-1032
-
(2002)
Mol. Pharmacol.
, vol.61
, pp. 1025-1032
-
-
Greasley, P.J.1
Fanelli, F.2
Rossier, O.3
Abuin, L.4
Cotecchia, S.5
-
18
-
-
0037192858
-
Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6
-
Shapiro D.A., Kristiansen K., Weiner D.M., Kroeze W.K., and Roth B.L. Evidence for a model of agonist-induced activation of 5-hydroxytryptamine 2A serotonin receptors that involves the disruption of a strong ionic interaction between helices 3 and 6. J. Biol. Chem. 277 (2002) 11441-11449
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 11441-11449
-
-
Shapiro, D.A.1
Kristiansen, K.2
Weiner, D.M.3
Kroeze, W.K.4
Roth, B.L.5
-
19
-
-
0033546197
-
Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation
-
Sheikh S.P., Vilardaga J.P., Baranski T.J., Lichtarge O., Iiri T., Meng E.C., et al. Similar structures and shared switch mechanisms of the beta2-adrenoceptor and the parathyroid hormone receptor. Zn(II) bridges between helices III and VI block activation. J. Biol. Chem. 274 (1999) 17033-17041
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 17033-17041
-
-
Sheikh, S.P.1
Vilardaga, J.P.2
Baranski, T.J.3
Lichtarge, O.4
Iiri, T.5
Meng, E.C.6
-
20
-
-
0035932989
-
Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor
-
Ghanouni P., Steenhuis J.J., Farrens D.L., and Kobilka B.K. Agonist-induced conformational changes in the G-protein-coupling domain of the beta 2 adrenergic receptor. Proc. Natl. Acad. Sci. USA 98 (2001) 5997-6002
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 5997-6002
-
-
Ghanouni, P.1
Steenhuis, J.J.2
Farrens, D.L.3
Kobilka, B.K.4
-
21
-
-
0032573218
-
Light-induced exposure of the cytoplasmic end of transmembrane helix seven in rhodopsin
-
Abdulaev N.G., and Ridge K.D. Light-induced exposure of the cytoplasmic end of transmembrane helix seven in rhodopsin. Proc. Natl. Acad. Sci. USA 95 (1998) 12854-12859
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 12854-12859
-
-
Abdulaev, N.G.1
Ridge, K.D.2
-
22
-
-
24344507257
-
Agonists and partial agonists of rhodopsin: retinals with ring modifications
-
erratum published in Biochemistry 44: 12914
-
Vogel R., Siebert F., Lüdeke S., Hirshfeld A., and Sheves M. Agonists and partial agonists of rhodopsin: retinals with ring modifications. Biochemistry 44 (2005) 11684-11699 erratum published in Biochemistry 44: 12914
-
(2005)
Biochemistry
, vol.44
, pp. 11684-11699
-
-
Vogel, R.1
Siebert, F.2
Lüdeke, S.3
Hirshfeld, A.4
Sheves, M.5
-
23
-
-
0027374544
-
Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants
-
Fahmy K., Jäger F., Beck M., Zvyaga T.A., Sakmar T.P., and Siebert F. Protonation states of membrane-embedded carboxylic acid groups in rhodopsin and metarhodopsin II: a Fourier-transform infrared spectroscopy study of site-directed mutants. Proc. Natl. Acad. Sci. USA 90 (1993) 10206-10210
-
(1993)
Proc. Natl. Acad. Sci. USA
, vol.90
, pp. 10206-10210
-
-
Fahmy, K.1
Jäger, F.2
Beck, M.3
Zvyaga, T.A.4
Sakmar, T.P.5
Siebert, F.6
-
24
-
-
0028017506
-
Identification of glutamic acid 113 as the Schiff base proton acceptor in the metarhodopsin II photointermediate of rhodopsin
-
Jäger F., Fahmy K., Sakmar T.P., and Siebert F. Identification of glutamic acid 113 as the Schiff base proton acceptor in the metarhodopsin II photointermediate of rhodopsin. Biochemistry 33 (1994) 10878-10882
-
(1994)
Biochemistry
, vol.33
, pp. 10878-10882
-
-
Jäger, F.1
Fahmy, K.2
Sakmar, T.P.3
Siebert, F.4
-
25
-
-
0027364707
-
Fourier transform infrared difference spectroscopy of rhodopsin mutants: light activation of rhodopsin causes hydrogen-bonding change in residue aspartic acid-83 during Meta II formation
-
Rath P., DeCaluwe L.L., Bovee-Geurts P.H., DeGrip W.J., and Rothschild K.J. Fourier transform infrared difference spectroscopy of rhodopsin mutants: light activation of rhodopsin causes hydrogen-bonding change in residue aspartic acid-83 during Meta II formation. Biochemistry 32 (1993) 10277-10282
-
(1993)
Biochemistry
, vol.32
, pp. 10277-10282
-
-
Rath, P.1
DeCaluwe, L.L.2
Bovee-Geurts, P.H.3
DeGrip, W.J.4
Rothschild, K.J.5
-
26
-
-
0031761606
-
Evidence for the specific interaction of a lipid molecule with rhodopsin which is altered in the transition to the active state metarhodopsin II
-
Beck M., Siebert F., and Sakmar T.P. Evidence for the specific interaction of a lipid molecule with rhodopsin which is altered in the transition to the active state metarhodopsin II. FEBS Lett. 436 (1998) 304-308
-
(1998)
FEBS Lett.
, vol.436
, pp. 304-308
-
-
Beck, M.1
Siebert, F.2
Sakmar, T.P.3
-
27
-
-
33845505655
-
Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes
-
Botelho A.V., Huber T., Sakmar T.P., and Brown M.F. Curvature and hydrophobic forces drive oligomerization and modulate activity of rhodopsin in membranes. Biophys. J. 91 (2006) 4464-4477
-
(2006)
Biophys. J.
, vol.91
, pp. 4464-4477
-
-
Botelho, A.V.1
Huber, T.2
Sakmar, T.P.3
Brown, M.F.4
-
28
-
-
0034473318
-
The infrared absorption of amino acid side chains
-
Barth A. The infrared absorption of amino acid side chains. Prog. Biophys. Mol. Biol. 74 (2000) 141-173
-
(2000)
Prog. Biophys. Mol. Biol.
, vol.74
, pp. 141-173
-
-
Barth, A.1
-
29
-
-
22144464025
-
A vibrational spectral maker for probing the hydrogen-bonding status of protonated Asp and Glu residues
-
Nie B., Stutzman J., and Xie A. A vibrational spectral maker for probing the hydrogen-bonding status of protonated Asp and Glu residues. Biophys. J. 88 (2005) 2833-2847
-
(2005)
Biophys. J.
, vol.88
, pp. 2833-2847
-
-
Nie, B.1
Stutzman, J.2
Xie, A.3
-
31
-
-
0033637518
-
Rhodopsin activation affects the environment of specific neighboring phospholipids: an FTIR spectroscopic study
-
Isele J., Sakmar T.P., and Siebert F. Rhodopsin activation affects the environment of specific neighboring phospholipids: an FTIR spectroscopic study. Biophys. J. 79 (2000) 3063-3071
-
(2000)
Biophys. J.
, vol.79
, pp. 3063-3071
-
-
Isele, J.1
Sakmar, T.P.2
Siebert, F.3
-
32
-
-
0031446595
-
Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state
-
Kim J.M., Altenbach C., Thurmond R.L., Khorana H.G., and Hubbell W.L. Structure and function in rhodopsin: rhodopsin mutants with a neutral amino acid at E134 have a partially activated conformation in the dark state. Proc. Natl. Acad. Sci. USA 94 (1997) 14273-14278
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 14273-14278
-
-
Kim, J.M.1
Altenbach, C.2
Thurmond, R.L.3
Khorana, H.G.4
Hubbell, W.L.5
-
33
-
-
0027723278
-
Rhodopsin activation: effects on the metarhodopsin I-metarhodopsin II equilibrium of neutralization or introduction of charged amino acids within putative transmembrane segments
-
Weitz C.J., and Nathans J. Rhodopsin activation: effects on the metarhodopsin I-metarhodopsin II equilibrium of neutralization or introduction of charged amino acids within putative transmembrane segments. Biochemistry 32 (1993) 14176-14182
-
(1993)
Biochemistry
, vol.32
, pp. 14176-14182
-
-
Weitz, C.J.1
Nathans, J.2
-
34
-
-
36448995359
-
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor
-
Cherezov V., Rosenbaum D.M., Hanson M.A., Rasmussen S.G., Thian F.S., Kobilka T.S., et al. High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor. Science 318 (2007) 1258-1265
-
(2007)
Science
, vol.318
, pp. 1258-1265
-
-
Cherezov, V.1
Rosenbaum, D.M.2
Hanson, M.A.3
Rasmussen, S.G.4
Thian, F.S.5
Kobilka, T.S.6
-
35
-
-
36448978229
-
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function
-
Rosenbaum D.M., Cherezov V., Hanson M.A., Rasmussen S.G., Thian F.S., Kobilka T.S., et al. GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function. Science 318 (2007) 1266-1273
-
(2007)
Science
, vol.318
, pp. 1266-1273
-
-
Rosenbaum, D.M.1
Cherezov, V.2
Hanson, M.A.3
Rasmussen, S.G.4
Thian, F.S.5
Kobilka, T.S.6
-
36
-
-
33746382921
-
Coupling ligand structure to specific conformational switches in the beta2-adrenoceptor
-
Yao X., Parnot C., Deupi X., Ratnala V.R., Swaminath G., Farrens D.L., and Kobilka B. Coupling ligand structure to specific conformational switches in the beta2-adrenoceptor. Nat. Chem. Biol. 2 (2006) 417-422
-
(2006)
Nat. Chem. Biol.
, vol.2
, pp. 417-422
-
-
Yao, X.1
Parnot, C.2
Deupi, X.3
Ratnala, V.R.4
Swaminath, G.5
Farrens, D.L.6
Kobilka, B.7
-
37
-
-
0020020855
-
Preparation of retinal rod outer segments
-
Papermaster D.S. Preparation of retinal rod outer segments. Methods Enzymol. 81 (1982) 48-52
-
(1982)
Methods Enzymol.
, vol.81
, pp. 48-52
-
-
Papermaster, D.S.1
-
38
-
-
0020007210
-
Purification of bovine rhodopsin over cancanavalin A-Sepharose
-
DeGrip W.J. Purification of bovine rhodopsin over cancanavalin A-Sepharose. Methods Enzymol. 81 (1982) 197-207
-
(1982)
Methods Enzymol.
, vol.81
, pp. 197-207
-
-
DeGrip, W.J.1
-
39
-
-
1842786894
-
Rhodopsin photoproducts in 2D crystals
-
Vogel R., Ruprecht J., Mielke T., Villa C., Schertler G.F.X., and Siebert F. Rhodopsin photoproducts in 2D crystals. J. Mol. Biol. 338 (2004) 597-609
-
(2004)
J. Mol. Biol.
, vol.338
, pp. 597-609
-
-
Vogel, R.1
Ruprecht, J.2
Mielke, T.3
Villa, C.4
Schertler, G.F.X.5
Siebert, F.6
-
40
-
-
0022431824
-
Rhodopsin-egg phosphatidylcholine reconstitution by an octyl glucoside dilution procedure
-
Jackson M.L., and Litman B.J. Rhodopsin-egg phosphatidylcholine reconstitution by an octyl glucoside dilution procedure. Biochim. Biophys. Acta 812 (1985) 369-376
-
(1985)
Biochim. Biophys. Acta
, vol.812
, pp. 369-376
-
-
Jackson, M.L.1
Litman, B.J.2
-
41
-
-
0037133528
-
Function of extracellular loop 2 in rhodopsin: glutamic acid 181 modulates stability and absorption wavelength of metarhodopsin II
-
Yan E.C., Kazmi M.A., De S., Chang B.S., Seibert C., Marin E.P., et al. Function of extracellular loop 2 in rhodopsin: glutamic acid 181 modulates stability and absorption wavelength of metarhodopsin II. Biochemistry 41 (2002) 3620-3627
-
(2002)
Biochemistry
, vol.41
, pp. 3620-3627
-
-
Yan, E.C.1
Kazmi, M.A.2
De, S.3
Chang, B.S.4
Seibert, C.5
Marin, E.P.6
-
42
-
-
0031473847
-
SWISS-MODEL and the Swiss-pdb Viewer: an environment for comparative protein modeling
-
Guex N., and Peitsch M.C. SWISS-MODEL and the Swiss-pdb Viewer: an environment for comparative protein modeling. Electrophoresis 18 (1997) 2714-2723
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
|