A hypoxia-induced positive feedback loop promotes hypoxia-inducible factor 1α stability through mir-210 suppression of glycerol-3-phosphate dehydrogenase 1-like

Molecular and Cellular Biology

Volumn 31, Issue 13, 2011, Pages 2696-2706

  Kelly, Timothy J ^a,b,c   Souza, Amanda L ^d   Clish, Clary B ^d   Puigserver, Pere ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d BROAD INSTITUTE OF MIT AND HARVARD   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCEROL 3 PHOSPHATE DEHYDROGENASE; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MICRORNA; MICRORNA 210; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROTEASOME; REGULATOR PROTEIN; REGULATOR PROTEIN GPD1L; UNCLASSIFIED DRUG;

3' UNTRANSLATED REGION; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENE TARGETING; HUMAN; HUMAN CELL; HYDROXYLATION; HYPOXIA; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; TRANSCRIPTION REGULATION;

CELL HYPOXIA; FEEDBACK, PHYSIOLOGICAL; GLYCEROLPHOSPHATE DEHYDROGENASE; HEK293 CELLS; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICRORNAS; NEOPLASMS; PROTEIN STABILITY; TRANSCRIPTION, GENETIC;

EID: 79959425207     PISSN: 02707306     EISSN: 10985549     Source Type: Journal    
DOI: 10.1128/MCB.01242-10     Document Type: Article

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