The key residues of active sites on the catalytic fragment for paclitaxel interacting with poly (adp-ribose) polymerase

Journal of Biomolecular Structure and Dynamics

Volumn 28, Issue 6, 2011, Pages 881-893

  Wang, Yue ^a   Bian, Fuyong ^a   Deng, Shengrong ^a   Shi, Qiang ^b   Ge, Maofa ^b   Wang, Shu ^b   Zhang, Xingkang ^b   Xu, Sichuan ^a,b  

^a YUNNAN UNIVERSITY   (China)

^b INSTITUTE OF CHEMISTRY   (China)

Author keywords

Active site; Binding pocket; DFT; MD simulation; Paclitaxel; Poly(ADP Ribose) Polymerase

Indexed keywords

ASPARTIC ACID; BETA TUBULIN; GLUTAMIC ACID; GLYCINE; HISTIDINE; LYSINE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PACLITAXEL; TYROSINE;

ANTINEOPLASTIC ACTIVITY; ARTICLE; BINDING SITE; CANCER CELL CULTURE; CONTROLLED STUDY; DRUG CONFORMATION; DRUG PROTEIN BINDING; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME ACTIVE SITE; ENZYME STRUCTURE; INHIBITION KINETICS; MOLECULAR DOCKING; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN INTERACTION; PROTEIN TARGETING;

EID: 79958734879     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2011.10508615     Document Type: Article

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