NMR and molecular modeling study of the conformations of taxol 2′-acetate in chloroform and aqueous dimethyl sulfoxide solutions

Journal of Medicinal Chemistry

Volumn 39, Issue 7, 1996, Pages 1555-1559

  Williams, Howard J ^a   Moyna, Guillermo ^a   Scott, A I ^a   Swindell, Charles S ^b   Chirlian, Lisa E ^b   Heerding, Julia M ^b   Williams, David K ^b  

^a TEXAS A AND M UNIVERSITY   (United States)

^b BRYN MAWR COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHLOROFORM; DIMETHYL SULFOXIDE; DOCETAXEL; PACLITAXEL DERIVATIVE; TAXOL 2' ACETATE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER INHIBITION; DEUTERON NUCLEAR MAGNETIC RESONANCE; DRUG BINDING SITE; DRUG CONFORMATION; MICROTUBULE ASSEMBLY; MOLECULAR MODEL; POLYMERIZATION; STRUCTURE ACTIVITY RELATION;

ACETATES; ALKALOIDS; CHLOROFORM; DEUTERIUM; DIMETHYL SULFOXIDE; HYDROGEN BONDING; MAGNETIC RESONANCE SPECTROSCOPY; MICROTUBULES; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR STRUCTURE; PACLITAXEL; TAXOIDS;

EID: 0029968838     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950796q     Document Type: Article

References (31)

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