Conserved water mediated h-bonding dynamics of inhibitor, cofactor, asp 364 and asn 303 in human impdh ii

Journal of Biomolecular Structure and Dynamics

Volumn 26, Issue 4, 2009, Pages 497-507

  Bairagya, Hridoy R ^a   Mukhopadhyay, Bishnu P ^a   Sekar, K ^b  

^a NATIONAL INSTITUTE OF TECHNOLOGY   (India)

^b INDIAN INSTITUTE OF SCIENCE   (India)

Author keywords

IMPDH II; Inhibitor; Molecular Dynamics

Indexed keywords

AMINO ACID; ASPARAGINE; ASPARAGINE DERIVATIVE; ASPARTIC ACID; ASPARTIC ACID DERIVATIVE; INOSINATE DEHYDROGENASE; INOSINE MONOPHOSPHATE DEHYDROGENASE II; LIGAND; PURINE NUCLEOTIDE; UNCLASSIFIED DRUG; WATER;

ARTICLE; CHEMICAL STRUCTURE; COMPLEX FORMATION; ENZYME INHIBITION; HUMAN; HYDROGEN BOND; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN STRUCTURE; ROENTGEN SPECTROSCOPY; SOLVATION; STEREOCHEMISTRY; WATER ANALYSIS;

ASPARAGINE; ASPARTIC ACID; CATALYTIC DOMAIN; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; ENZYME STABILITY; HUMANS; HYDROGEN BONDING; IMP DEHYDROGENASE; INOSINE MONOPHOSPHATE; LIGANDS; NAD; THERMODYNAMICS; WATER;

EID: 60849116429     PISSN: 07391102     EISSN: 15380254     Source Type: Journal    
DOI: 10.1080/07391102.2009.10507265     Document Type: Article

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