Inhibitor and NAD+ binding to poly(ADP-ribose) polymerase as derived from crystal structures and homology modeling

Biochemistry

Volumn 37, Issue 11, 1998, Pages 3893-3900

  Ruf, Armin ^a   De Murcia, Gilbert ^b   Schulz, Georg E ^a  

^a UNIVERSITY OF FREIBURG   (Germany)

^b UNIVERSITÉ DE STRASBOURG   (France)

Author keywords

[No Author keywords available]

Indexed keywords

3,4 DIHYDRO 5 METHYLISOQUINOLINE; BACTERIAL TOXIN; NICOTINAMIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; NICOTINAMIDE ADENINE DINUCLEOTIDE INHIBITOR; PD 128763; UNCLASSIFIED DRUG;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; CRYSTAL STRUCTURE; DNA STRAND BREAKAGE; ENZYME INHIBITION; PRIORITY JOURNAL; PROTEIN MODIFICATION; SEQUENCE HOMOLOGY; STRUCTURE ANALYSIS;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; CHICKENS; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; DIPHTHERIA TOXIN; ISOQUINOLINES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NAD; NIACINAMIDE; POLY(ADP-RIBOSE) POLYMERASES; PROTEIN BINDING; SEQUENCE HOMOLOGY, AMINO ACID;

BACTERIA (MICROORGANISMS);

EID: 0032539957     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi972383s     Document Type: Article

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