메뉴 건너뛰기




Volumn 11, Issue 4, 2011, Pages 398-407

Molecular mechanisms of anti-cancer action of garlic compounds in neuroblastoma

Author keywords

Apoptosis; Calpain; Caspases; Diallyl disulfide; Diallyl sufide; Neuroblastoma

Indexed keywords

ALLYL SULFIDE; CASPASE; CASPASE 3; CASPASE ACTIVATED DEOXYRIBONUCLEASE; CELL CYCLE PROTEIN 20; CHECKPOINT KINASE 1; CYCLIN B1; CYTOCHROME C; DEATH DOMAIN RECEPTOR SIGNALING ADAPTOR PROTEIN; DEATH RECEPTOR 5; DIALLYL DISULFIDE; DIALLYL TRISULFIDE; ENDONUCLEASE G; GARLIC EXTRACT; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INHIBITOR OF APOPTOSIS PROTEIN; MATRIX METALLOPROTEINASE; NEURONAL NITRIC OXIDE SYNTHASE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE 1; NITRIC OXIDE; PLANT MEDICINAL PRODUCT; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; SYNAPTOPHYSIN; UNINDEXED DRUG; X LINKED INHIBITOR OF APOPTOSIS;

EID: 79958157741     PISSN: 18715206     EISSN: 18755992     Source Type: Journal    
DOI: 10.2174/187152011795677553     Document Type: Review
Times cited : (26)

References (95)
  • 1
    • 0037366067 scopus 로고    scopus 로고
    • Neuroblastoma: Biological insights into a clinical enigma
    • Brodeur, G.M. Neuroblastoma: biological insights into a clinical enigma. Nat. Rev. Cancer., 2003, 3, 203-216.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 203-216
    • Brodeur, G.M.1
  • 2
    • 70350144841 scopus 로고    scopus 로고
    • Neuroblastoma: Biology and staging
    • Mueller, S.; Matthay, K.K. Neuroblastoma: biology and staging. Curr. Oncol. Rep., 2009, 11, 431-438.
    • (2009) Curr. Oncol. Rep , vol.11 , pp. 431-438
    • Mueller, S.1    Matthay, K.K.2
  • 4
    • 79952098597 scopus 로고    scopus 로고
    • Oncogenic mutations of ALK in neuroblastoma
    • Ogawa, S.; Takita, J.; Sanada, M.; Hayashi, Y. Oncogenic mutations of ALK in neuroblastoma. Cancer Sci., 2011, 102, 302-308.
    • (2011) Cancer Sci , vol.102 , pp. 302-308
    • Ogawa, S.1    Takita, J.2    Sanada, M.3    Hayashi, Y.4
  • 6
    • 79551480067 scopus 로고    scopus 로고
    • The connections between neural crest development and neuroblastoma
    • Jiang, M.; Stanke, J.; Lahti, J.M. The connections between neural crest development and neuroblastoma. Curr. Top. Dev. Biol., 2011, 94, 77-127.
    • (2011) Curr. Top. Dev. Biol , vol.94 , pp. 77-127
    • Jiang, M.1    Stanke, J.2    Lahti, J.M.3
  • 7
    • 0033034390 scopus 로고    scopus 로고
    • Molecular biology of neuroblastoma
    • Maris, J.M.; Matthay, K.K. Molecular biology of neuroblastoma. J. Clin. Oncol., 1999, 17, 2264-2279.
    • (1999) J. Clin. Oncol , vol.17 , pp. 2264-2279
    • Maris, J.M.1    Matthay, K.K.2
  • 10
    • 70249085177 scopus 로고    scopus 로고
    • N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53
    • Janardhanan, R.; Banik, N.L.; Ray, S.K. N-Myc down regulation induced differentiation, early cell cycle exit, and apoptosis in human malignant neuroblastoma cells having wild type or mutant p53. Biochem. Pharmacol., 2009, 78, 1105-1114.
    • (2009) Biochem. Pharmacol , vol.78 , pp. 1105-1114
    • Janardhanan, R.1    Banik, N.L.2    Ray, S.K.3
  • 13
    • 2442480795 scopus 로고    scopus 로고
    • Multiple cell death pathways as regulators of tumour initiation and progression
    • Jaattela, M. Multiple cell death pathways as regulators of tumour initiation and progression. Oncogene, 2004, 23, 2746-2756.
    • (2004) Oncogene , vol.23 , pp. 2746-2756
    • Jaattela, M.1
  • 14
    • 0037468930 scopus 로고    scopus 로고
    • Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells
    • Lacour, S.; Micheau, O.; Hammann, A.; Drouineaud, V.; Tschopp, J.; Solary, E.; Dimanche-Boitrel, M.T. Chemotherapy enhances TNF-related apoptosis-inducing ligand DISC assembly in HT29 human colon cancer cells. Oncogene, 2003, 22, 1807-1816.
    • (2003) Oncogene , vol.22 , pp. 1807-1816
    • Lacour, S.1    Micheau, O.2    Hammann, A.3    Drouineaud, V.4    Tschopp, J.5    Solary, E.6    Dimanche-Boitrel, M.T.7
  • 16
    • 16844377506 scopus 로고    scopus 로고
    • Recent advances in understanding the cell death pathways activated by anticancer therapy
    • Kim, R. Recent advances in understanding the cell death pathways activated by anticancer therapy. Cancer, 2005, 103, 1551-1560.
    • (2005) Cancer , vol.103 , pp. 1551-1560
    • Kim, R.1
  • 17
    • 78549267195 scopus 로고    scopus 로고
    • Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification
    • Roy Choudhury, S.; Karmakar, S.; Banik, N.L.; Ray, S.K. Synergistic efficacy of sorafenib and genistein in growth inhibition by down regulating angiogenic and survival factors and increasing apoptosis through upregulation of p53 and p21 in malignant neuroblastoma cells having N-Myc amplification or non-amplification. Invest. New Drugs, 2010, 28, 812-824.
    • (2010) Invest. New Drugs , vol.28 , pp. 812-824
    • Choudhury, S.R.1    Karmakar, S.2    Banik, N.L.3    Ray, S.K.4
  • 18
    • 0037426614 scopus 로고    scopus 로고
    • Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice
    • Shibata, M.; Hattori, H.; Sasaki, T.; Gotoh, J.; Hamada, J.; Fukuuchi, Y. Activation of caspase-12 by endoplasmic reticulum stress induced by transient middle cerebral artery occlusion in mice. Neuroscience, 2003, 118, 491-499.
    • (2003) Neuroscience , vol.118 , pp. 491-499
    • Shibata, M.1    Hattori, H.2    Sasaki, T.3    Gotoh, J.4    Hamada, J.5    Fukuuchi, Y.6
  • 19
    • 68349144682 scopus 로고    scopus 로고
    • Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts
    • Karmakar, S.; Choudhury, S.R.; Banik, N.L.; Ray, S.K. Combination of N-(4-hydroxyphenyl) retinamide and genistein increased apoptosis in neuroblastoma SK-N-BE2 and SH-SY5Y xenografts. Neuroscience, 2009, 163, 286-295.
    • (2009) Neuroscience , vol.163 , pp. 286-295
    • Karmakar, S.1    Choudhury, S.R.2    Banik, N.L.3    Ray, S.K.4
  • 20
  • 21
    • 33746422972 scopus 로고    scopus 로고
    • Activation of multiple molecular mechanisms for apoptosis in human malignant glioblastoma T98G and U87MG cells treated with sulforaphane
    • Karmakar, S.; Weinberg, M.S.; Banik, N.L.; Patel, S.J.; Ray, S.K. Activation of multiple molecular mechanisms for apoptosis in human malignant glioblastoma T98G and U87MG cells treated with sulforaphane. Neuroscience, 2006, 141, 1265-1280.
    • (2006) Neuroscience , vol.141 , pp. 1265-1280
    • Karmakar, S.1    Weinberg, M.S.2    Banik, N.L.3    Patel, S.J.4    Ray, S.K.5
  • 22
    • 18144407551 scopus 로고    scopus 로고
    • Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: Evidence from calpastatin mutant mice
    • Takano, J.; Tomioka, M.; Tsubuki, S.; Higuchi, M.; Iwata, N.; Itohara, S.; Maki, M.; Saido, T.C. Calpain mediates excitotoxic DNA fragmentation via mitochondrial pathways in adult brains: evidence from calpastatin mutant mice. J. Biol. Chem., 2005, 280, 16175-16184.
    • (2005) J. Biol. Chem , vol.280 , pp. 16175-16184
    • Takano, J.1    Tomioka, M.2    Tsubuki, S.3    Higuchi, M.4    Iwata, N.5    Itohara, S.6    Maki, M.7    Saido, T.C.8
  • 23
    • 0037401562 scopus 로고    scopus 로고
    • Cell death regulation by the Bcl-2 protein family in the mitochondria
    • Tsujimoto, Y. Cell death regulation by the Bcl-2 protein family in the mitochondria. J. Cell Physiol., 2003, 195, 158-167.
    • (2003) J. Cell Physiol , vol.195 , pp. 158-167
    • Tsujimoto, Y.1
  • 24
    • 2442621492 scopus 로고    scopus 로고
    • Role of AIF in caspase-dependent and caspase-independent cell death
    • Cregan, S.P.; Dawson, V.L.; Slack, R.S. Role of AIF in caspase-dependent and caspase-independent cell death. Oncogene, 2004, 23, 2785-2796.
    • (2004) Oncogene , vol.23 , pp. 2785-2796
    • Cregan, S.P.1    Dawson, V.L.2    Slack, R.S.3
  • 25
    • 0042859821 scopus 로고    scopus 로고
    • Role of the mitochondrial permeability transition in myocardial disease
    • Weiss, J.N.; Korge, P.; Honda, H.M.; Ping, P. Role of the mitochondrial permeability transition in myocardial disease. Circ. Res., 2003, 93, 292-301.
    • (2003) Circ. Res , vol.93 , pp. 292-301
    • Weiss, J.N.1    Korge, P.2    Honda, H.M.3    Ping, P.4
  • 27
    • 3042766027 scopus 로고    scopus 로고
    • The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195
    • Chen, J.; Freeman, A.; Liu, J.; Dai Q.; Lee, R.M. The apoptotic effect of HA14-1, a Bcl-2-interacting small molecular compound, requires Bax translocation and is enhanced by PK11195. Mol. Cancer Ther., 2002,1, 961-967.
    • (2002) Mol. Cancer Ther , vol.1 , pp. 961-967
    • Chen, J.1    Freeman, A.2    Liu, J.3    Dai, Q.4    Lee, R.M.5
  • 28
    • 0031037897 scopus 로고    scopus 로고
    • The release of cytochrome c from mitochondria: A primary site for Bcl-2 regulation of apoptosis
    • Kluck, R.M.; Bossy-Wetzel, E.; Green, D.R.; Newmeyer, D.D. The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis. Science, 1997, 275, 1132-1136.
    • (1997) Science , vol.275 , pp. 1132-1136
    • Kluck, R.M.1    Bossy-Wetzel, E.2    Green, D.R.3    Newmeyer, D.D.4
  • 29
    • 0031889132 scopus 로고    scopus 로고
    • Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis
    • Sakahira, H.; Enari, M.; Nagata, S. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature, 1998, 391, 96-99.
    • (1998) Nature , vol.391 , pp. 96-99
    • Sakahira, H.1    Enari, M.2    Nagata, S.3
  • 30
    • 0034616945 scopus 로고    scopus 로고
    • Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
    • Du, C; Fang, M.; Li, Y.; Li, L.; Wang, X. Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. Cell, 2000, 102, 33-42.
    • (2000) Cell , vol.102 , pp. 33-42
    • Du, C.1    Fang, M.2    Li, Y.3    Li, L.4    Wang, X.5
  • 33
    • 0032508414 scopus 로고    scopus 로고
    • NF-kB antiapoptosis: Induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation
    • Wang, C.Y.; Mayo, M.W.; Korneluk, R.G.; Goeddel, D.V.; Baldwin, A.S. NF-kB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activation. Science, 1998, 281, 1680-1683.
    • (1998) Science , vol.281 , pp. 1680-1683
    • Wang, C.Y.1    Mayo, M.W.2    Korneluk, R.G.3    Goeddel, D.V.4    Baldwin, A.S.5
  • 34
    • 19344367506 scopus 로고    scopus 로고
    • Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression
    • Notarbartolo, M.; Poma, P.; Perri, D.; Dusonchet, L.; Cervello, M.; D'Alessandro, N. Antitumor effects of curcumin, alone or in combination with cisplatin or doxorubicin, on human hepatic cancer cells. Analysis of their possible relationship to changes in NF-kB activation levels and in IAP gene expression. Cancer Lett., 2005, 224, 53-65.
    • (2005) Cancer Lett , vol.224 , pp. 53-65
    • Notarbartolo, M.1    Poma, P.2    Perri, D.3    Dusonchet, L.4    Cervello, M.5    D'Alessandro, N.6
  • 35
    • 1942486873 scopus 로고    scopus 로고
    • NF-KB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion
    • Zou, T.; Rao, J.N.; Guo, X.; Liu, L.; Zhang, H.M.; Strauch, E.D.; Bass, B.L.; Wang, J.Y. NF-KB-mediated IAP expression induces resistance of intestinal epithelial cells to apoptosis after polyamine depletion. Am. J. Physiol. Cell Physiol., 2004, 286, C1009-1018.
    • (2004) Am. J. Physiol. Cell Physiol , vol.286
    • Zou, T.1    Rao, J.N.2    Guo, X.3    Liu, L.4    Zhang, H.M.5    Strauch, E.D.6    Bass, B.L.7    Wang, J.Y.8
  • 36
    • 0037663452 scopus 로고    scopus 로고
    • Direct interaction between surviving and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during Taxol-induced apoptosis
    • Song, Z.; Yao, X.; Wu, M. Direct interaction between surviving and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during Taxol-induced apoptosis. J. Biol. Chem., 2003, 278, 23130-23140.
    • (2003) J. Biol. Chem , vol.278 , pp. 23130-23140
    • Song, Z.1    Yao, X.2    Wu, M.3
  • 37
    • 3042679658 scopus 로고    scopus 로고
    • Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells
    • Hasenjäger, A.; Gillissen, B.; Müller, A.; Normand, G.; Hemmati, P.G.; Schuler, M.; Dörken, B.; Daniel, P. T. Smac induces cytochrome c release and apoptosis independently from Bax/Bcl-x(L) in a strictly caspase-3-dependent manner in human carcinoma cells. Oncogene, 2004, 23, 4523-4535.
    • (2004) Oncogene , vol.23 , pp. 4523-4535
    • Hasenjäger, A.1    Gillissen, B.2    Müller, A.3    Normand, G.4    Hemmati, P.G.5    Schuler, M.6    Dörken, B.7    Daniel, P.T.8
  • 38
    • 0038722727 scopus 로고    scopus 로고
    • Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis
    • Yang, Q. H.; Church-Hajduk, R.; Ren, J.; Newton, M.L.; Du, C. Omi/HtrA2 catalytic cleavage of inhibitor of apoptosis (IAP) irreversibly inactivates IAPs and facilitates caspase activity in apoptosis. Genes Dev., 2003,17, 1487-1496.
    • (2003) Genes Dev , vol.17 , pp. 1487-1496
    • Yang, Q.H.1    Church-Hajduk, R.2    Ren, J.3    Newton, M.L.4    Du, C.5
  • 39
    • 0742324395 scopus 로고    scopus 로고
    • Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways
    • Suzuki, Y.; Takahashi-Niki, K.; Akagi, T.; Hashikawa, T.; Takaha-shi, R. Mitochondrial protease Omi/HtrA2 enhances caspase activation through multiple pathways. Cell Death Differ., 2004,11, 208-216.
    • (2004) Cell Death Differ , vol.11 , pp. 208-216
    • Suzuki, Y.1    Takahashi-Niki, K.2    Akagi, T.3    Hashikawa, T.4    Takaha-Shi, R.5
  • 41
    • 14844328621 scopus 로고    scopus 로고
    • Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria
    • Polster, B.M.; Basañez, G.; Etxebarria, A.; Hardwick, J.M.; Nicholls, D.G. Calpain I induces cleavage and release of apoptosis-inducing factor from isolated mitochondria. J. Biol. Chem., 2005, 280, 6447-6454.
    • (2005) J. Biol. Chem , vol.280 , pp. 6447-6454
    • Polster, B.M.1    Basañez, G.2    Etxebarria, A.3    Hardwick, J.M.4    Nicholls, D.G.5
  • 44
    • 0035811496 scopus 로고    scopus 로고
    • Endonuclease G is an apoptotic DNase when released from mitochondria
    • Li, L. Y.; Luo, X.; Wang, X. Endonuclease G is an apoptotic DNase when released from mitochondria. Nature, 2001, 412, 95-99.
    • (2001) Nature , vol.412 , pp. 95-99
    • Li, L.Y.1    Luo, X.2    Wang, X.3
  • 45
    • 0032508952 scopus 로고    scopus 로고
    • Trends in alternative medicine use in the United States, 1990-1997: Results of a follow-up national survey
    • Eisenberg, D.M.; Davis, R.B.; Ettner, S.L.; Appel, S.; Wilkey, S.; Von Rompay, M.; Kessler, R.C. Trends in alternative medicine use in the United States, 1990-1997: results of a follow-up national survey. J. Am. Med. Asooc., 1998, 280, 1569-1575.
    • (1998) J. Am. Med. Asooc , vol.280 , pp. 1569-1575
    • Eisenberg, D.M.1    Davis, R.B.2    Ettner, S.L.3    Appel, S.4    Wilkey, S.5    von Rompay, M.6    Kessler, R.C.7
  • 46
    • 0036955121 scopus 로고    scopus 로고
    • Botanicals in cancer chemoprevention
    • Park, E.J.; Pezzuto, J.M. Botanicals in cancer chemoprevention. Cancer Metastasis Rev., 2002, 21, 231-255.
    • (2002) Cancer Metastasis Rev , vol.21 , pp. 231-255
    • Park, E.J.1    Pezzuto, J.M.2
  • 47
    • 5144220818 scopus 로고    scopus 로고
    • Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: A review
    • Herman-Antosiewicz, A.; Singh, S.V. Signal transduction pathways leading to cell cycle arrest and apoptosis induction in cancer cells by Allium vegetable-derived organosulfur compounds: a review. Mutat. Res., 2004, 555, 121-131.
    • (2004) Mutat. Res , vol.555 , pp. 121-131
    • Herman-Antosiewicz, A.1    Singh, S.V.2
  • 49
    • 76749104656 scopus 로고    scopus 로고
    • Diallyl trisulfide induces Bcl-2 and caspase-3-dependent apoptosis via downregulation of Akt phosphorylation in human T24 bladder cancer cells
    • Wang, Y.B.; Qin, J.; Zheng, X.Y.; Bai, Y.; Yang, K.; Xie, L.P. Diallyl trisulfide induces Bcl-2 and caspase-3-dependent apoptosis via downregulation of Akt phosphorylation in human T24 bladder cancer cells. Phytomedicine, 2010, 17, 363-368.
    • (2010) Phytomedicine , vol.17 , pp. 363-368
    • Wang, Y.B.1    Qin, J.2    Zheng, X.Y.3    Bai, Y.4    Yang, K.5    Xie, L.P.6
  • 50
    • 0026736766 scopus 로고
    • Enhancing effects of diallyl sulfide on hepatocarcinogenesis and inhibitory actions of the related diallyl disulfide on colon and renal carcinogenesis in rats
    • Takahashi, S.; Hakoi, K.; Yada, H.; Hirose, M.; Ito, N.; Fukushima, S. Enhancing effects of diallyl sulfide on hepatocarcinogenesis and inhibitory actions of the related diallyl disulfide on colon and renal carcinogenesis in rats. Carcinogenesis, 1992, 13, 1513-1518.
    • (1992) Carcinogenesis , vol.13 , pp. 1513-1518
    • Takahashi, S.1    Hakoi, K.2    Yada, H.3    Hirose, M.4    Ito, N.5    Fukushima, S.6
  • 52
    • 0026780968 scopus 로고
    • Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis
    • Wargovich, M.J.; Imada, O.; Stephens, L.C. Initiation and post-initiation chemopreventive effects of diallyl sulfide in esophageal carcinogenesis. Cancer Lett., 1992, 64, 39-42.
    • (1992) Cancer Lett , vol.64 , pp. 39-42
    • Wargovich, M.J.1    Imada, O.2    Stephens, L.C.3
  • 53
    • 0023739534 scopus 로고
    • Effects of organosulfur compounds from garlic and onions on benzo[a] pyrene-induced neoplasia and glutathione S-transferase activity in the mouse
    • Sparnins, V.L.; Barany, G.; Wattenberg, L.W. Effects of organosulfur compounds from garlic and onions on benzo[a] pyrene-induced neoplasia and glutathione S-transferase activity in the mouse. Carcinogenesis, 1988, 9, 131-134.
    • (1988) Carcinogenesis , vol.9 , pp. 131-134
    • Sparnins, V.L.1    Barany, G.2    Wattenberg, L.W.3
  • 54
    • 0023391171 scopus 로고
    • Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide, a component of garlic oil
    • Hayes, M.A.; Rushmore, T.H.; Goldberg, M.T. Inhibition of hepatocarcinogenic responses to 1,2-dimethylhydrazine by diallyl sulfide, a component of garlic oil. Carcinogenesis, 1987, 8, 1155-1157.
    • (1987) Carcinogenesis , vol.8 , pp. 1155-1157
    • Hayes, M.A.1    Rushmore, T.H.2    Goldberg, M.T.3
  • 55
    • 0030761364 scopus 로고    scopus 로고
    • Inhibitory effects of diallyl disulfide or aspirin on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary carcinogenesis in rats
    • Suzui, N.; Sugie, S.; Rahman, K.M.; Ohnishi, M.; Yoshimi, N.; Wakabayashi, K.; Mori, H. Inhibitory effects of diallyl disulfide or aspirin on 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine-induced mammary carcinogenesis in rats. Jpn. J. Cancer Res., 1997, 88, 705-711.
    • (1997) Jpn. J. Cancer Res , vol.88 , pp. 705-711
    • Suzui, N.1    Sugie, S.2    Rahman, K.M.3    Ohnishi, M.4    Yoshimi, N.5    Wakabayashi, K.6    Mori, H.7
  • 56
    • 9444241651 scopus 로고    scopus 로고
    • Modulation of p53 in 7,12-dimethylbenz[a]anthracene-induced skin tumors by diallyl sulfide in Swiss albino mice
    • Arora, A.; Siddiqui, I.A.; Shukla, Y. Modulation of p53 in 7,12-dimethylbenz[a]anthracene-induced skin tumors by diallyl sulfide in Swiss albino mice. Mol. Cancer Ther., 2004, 3, 1459-1466.
    • (2004) Mol. Cancer Ther , vol.3 , pp. 1459-1466
    • Arora, A.1    Siddiqui, I.A.2    Shukla, Y.3
  • 59
    • 78651306103 scopus 로고    scopus 로고
    • Role of Bim in diallyl trisulfide-induced cytotoxicity in human cancer cells. Role of Bim in diallyl trisulfide-induced cytotoxicity in human cancer cells
    • Lee, B. C.; Park, B.H.; Kim, S.Y.; Lee, Y.J. Role of Bim in diallyl trisulfide-induced cytotoxicity in human cancer cells. Role of Bim in diallyl trisulfide-induced cytotoxicity in human cancer cells. J. Cell Biochem., 2011, 112, 118-127.
    • (2011) J. Cell Biochem , vol.112 , pp. 118-127
    • Lee, B.C.1    Park, B.H.2    Kim, S.Y.3    Lee, Y.J.4
  • 60
    • 0034734611 scopus 로고    scopus 로고
    • Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines
    • Hong, Y. S.; Ham, Y.A.; Choi, J.H.; Kim, J. Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines. Exp. Mol. Med., 2000, 32, 127-134.
    • (2000) Exp. Mol. Med , vol.32 , pp. 127-134
    • Hong, Y.S.1    Ham, Y.A.2    Choi, J.H.3    Kim, J.4
  • 61
    • 3342895063 scopus 로고    scopus 로고
    • Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2
    • Xiao, D.; Choi, S.; Johnson, D. E.; Vogel, V.G.; Johnson, C.S.; Trump, D.L.; Lee, Y. J.; Singh, S.V. Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phosphorylation of Bcl-2. Oncogene, 2004, 23, 5594-6606.
    • (2004) Oncogene , vol.23 , pp. 5594-6606
    • Xiao, D.1    Choi, S.2    Johnson, D.E.3    Vogel, V.G.4    Johnson, C.S.5    Trump, D.L.6    Lee, Y.J.7    Singh, S.V.8
  • 62
    • 34548152518 scopus 로고    scopus 로고
    • Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cys-teine proteases for apoptosis in human glioblastoma T98G and U87MG cells
    • Das, A.; Banik, N.L.; Ray, S.K. Garlic compounds generate reactive oxygen species leading to activation of stress kinases and cys-teine proteases for apoptosis in human glioblastoma T98G and U87MG cells. Cancer, 2007, 110, 1083-1095.
    • (2007) Cancer , vol.110 , pp. 1083-1095
    • Das, A.1    Banik, N.L.2    Ray, S.K.3
  • 63
    • 0141842655 scopus 로고    scopus 로고
    • 2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide
    • Filomeni, G.; Aquilano, K.; Rotilio, G.; Ciriolo, M.R. Reactive oxygen species-dependent c-Jun NH2-terminal kinase/c-Jun signaling cascade mediates neuroblastoma cell death induced by diallyl disulfide. Cancer Res., 2003, 63, 5940-5949.
    • (2003) Cancer Res , vol.63 , pp. 5940-5949
    • Filomeni, G.1    Aquilano, K.2    Rotilio, G.3    Ciriolo, M.R.4
  • 64
    • 33947174588 scopus 로고    scopus 로고
    • Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells
    • Karmakar, S.; Banik, N.L.; Patel, S.J.; Ray, S.K. Garlic compounds induced calpain and intrinsic caspase cascade for apoptosis in human malignant neuroblastoma SH-SY5Y cells. Apoptosis, 2007, 12, 671-684.
    • (2007) Apoptosis , vol.12 , pp. 671-684
    • Karmakar, S.1    Banik, N.L.2    Patel, S.J.3    Ray, S.K.4
  • 65
    • 34248167167 scopus 로고    scopus 로고
    • Neuronal nitric oxide synthase protects neuroblastoma cells from oxidative stress mediated by garlic derivatives
    • Aquilano, K.; Filomeni, G.; Baldelli, S.; Piccirillo, S.; De Martino, A.; Rotilio, G.; Ciriolo, M.R. Neuronal nitric oxide synthase protects neuroblastoma cells from oxidative stress mediated by garlic derivatives. J. Neurochem., 2007, 101, 1327-1337.
    • (2007) J. Neurochem , vol.101 , pp. 1327-1337
    • Aquilano, K.1    Filomeni, G.2    Baldelli, S.3    Piccirillo, S.4    de Martino, A.5    Rotilio, G.6    Ciriolo, M.R.7
  • 66
    • 77953512362 scopus 로고    scopus 로고
    • Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells
    • Aquilano, K.; Vigilanza, P.; Filomeni, G.; Rotilio, G.; Ciriolo, M.R. Tau dephosphorylation and microfilaments disruption are upstream events of the anti-proliferative effects of DADS in SH-SY5Y cells. J. Cell. Mol. Med., 2010, 14, 564-577.
    • (2010) J. Cell. Mol. Med , vol.14 , pp. 564-577
    • Aquilano, K.1    Vigilanza, P.2    Filomeni, G.3    Rotilio, G.4    Ciriolo, M.R.5
  • 67
    • 0033735581 scopus 로고    scopus 로고
    • Cell cycle checkpoints and their inactivation in human cancer
    • Molinari, M. Cell cycle checkpoints and their inactivation in human cancer. Cell Prolif., 2000, 33, 261-274.
    • (2000) Cell Prolif , vol.33 , pp. 261-274
    • Molinari, M.1
  • 68
    • 0842324788 scopus 로고    scopus 로고
    • Recycling the cell cycle: Cyclins revisited
    • Murray, A.W. Recycling the cell cycle: cyclins revisited. Cell, 2004, 116, 221-234.
    • (2004) Cell , vol.116 , pp. 221-234
    • Murray, A.W.1
  • 69
    • 0031596406 scopus 로고    scopus 로고
    • cdc2 kinase activity and G2/M phase arrest induced by diallyl disulfide in HCT-15 cells
    • cdc2 kinase activity and G2/M phase arrest induced by diallyl disulfide in HCT-15 cells. Nutr. Cancer, 1998, 30, 169-174.
    • (1998) Nutr. Cancer , vol.30 , pp. 169-174
    • Knowles, L.M.1    Milner, J.A.2
  • 70
    • 0034130821 scopus 로고    scopus 로고
    • cdc2 kinase activity through changes in complex formation and phosphorylation
    • cdc2 kinase activity through changes in complex formation and phosphorylation. Carcinogenesis, 2000, 21, 1129-1134.
    • (2000) Carcinogenesis , vol.21 , pp. 1129-1134
    • Knowles, L.M.1    Milner, J.A.2
  • 71
    • 33750314181 scopus 로고    scopus 로고
    • The initiation of G2/M checkpoint by diallyl disulfide requires the activation of p38 MAP kinase in HL-60 cells
    • Tan, L.M.; Zhang, M.X.; Luo, H.M.; Zeng, Y.Z.; Li, J.M.; Cui, Z.W.; Zhang, X. H.; Tang, S.S. The initiation of G2/M checkpoint by diallyl disulfide requires the activation of p38 MAP kinase in HL-60 cells. Zhonghua Xue Ye Xue Za Zhi, 2004, 25, 273-276.
    • (2004) Zhonghua Xue Ye Xue Za Zhi , vol.25 , pp. 273-276
    • Tan, L.M.1    Zhang, M.X.2    Luo, H.M.3    Zeng, Y.Z.4    Li, J.M.5    Cui, Z.W.6    Zhang, X.H.7    Tang, S.S.8
  • 72
    • 33748202157 scopus 로고    scopus 로고
    • Garlic compound, diallyl disulfide induces cell cycle arrest in prostate cancer cell line PC-3
    • Arunkumar, A.; Vijayababu, M.R.; Srinivasan, N.; Aruldhas, M.M.; Arunakaran, J. Garlic compound, diallyl disulfide induces cell cycle arrest in prostate cancer cell line PC-3. Mol. Cell. Biochem., 2006, 288, 107-113.
    • (2006) Mol. Cell. Biochem , vol.288 , pp. 107-113
    • Arunkumar, A.1    Vijayababu, M.R.2    Srinivasan, N.3    Aruldhas, M.M.4    Arunakaran, J.5
  • 73
    • 28044435379 scopus 로고    scopus 로고
    • 2-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphos-phorylation of Cdc 25 C
    • Xiao, D.; Herman-Antosiewicz, A.; Antosiewicz, J.; Xiao, H.; Brisson, M.; Lazo, J.S.; Singh, S.V. Diallyl trisulfide-induced G2-M phase cell cycle arrest in human prostate cancer cells is caused by reactive oxygen species-dependent destruction and hyperphos-phorylation of Cdc 25 C. Oncogene, 2005, 24, 6256-6268.
    • (2005) Oncogene , vol.24 , pp. 6256-6268
    • Xiao, D.1    Herman-Antosiewicz, A.2    Antosiewicz, J.3    Xiao, H.4    Brisson, M.5    Lazo, J.S.6    Singh, S.V.7
  • 74
    • 23344431622 scopus 로고    scopus 로고
    • Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells
    • Herman-Antosiewicz, A.; Singh, S.V. Checkpoint kinase 1 regulates diallyl trisulfide-induced mitotic arrest in human prostate cancer cells. J. Biol. Chem., 2005, 280, 28519-28528.
    • (2005) J. Biol. Chem , vol.280 , pp. 28519-28528
    • Herman-Antosiewicz, A.1    Singh, S.V.2
  • 75
    • 34248177364 scopus 로고    scopus 로고
    • Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreven-tive constituent of processed garlic
    • Herman-Antosiewicz, A.; Stan, S.D.; Hahm, E.R.; Xiao, D.; Singh, S.V. Activation of a novel ataxia-telangiectasia mutated and Rad3 related/checkpoint kinase 1-dependent prometaphase checkpoint in cancer cells by diallyl trisulfide, a promising cancer chemopreven-tive constituent of processed garlic. Mol. Cancer. Ther., 2007, 6, 1249-1261.
    • (2007) Mol. Cancer. Ther , vol.6 , pp. 1249-1261
    • Herman-Antosiewicz, A.1    Stan, S.D.2    Hahm, E.R.3    Xiao, D.4    Singh, S.V.5
  • 76
    • 33744910333 scopus 로고    scopus 로고
    • 2-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells
    • Antosiewicz, J.; Herman-Antosiewicz, A.; Marynowski, S.W.; Singh, S.V. c-Jun NH2-terminal kinase signaling axis regulates diallyl trisulfide-induced generation of reactive oxygen species and cell cycle arrest in human prostate cancer cells. Cancer Res., 2006, 66, 5379-5386.
    • (2006) Cancer Res , vol.66 , pp. 5379-5386
    • Antosiewicz, J.1    Herman-Antosiewicz, A.2    Marynowski, S.W.3    Singh, S.V.4
  • 77
    • 0030867582 scopus 로고    scopus 로고
    • Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
    • Sanchez, Y.; Wong, C.; Thoma, R.S.; Richman, R.; Wu, Z.; Piwnica-Worms, H.; Elledge, S.J. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science, 1997, 277, 1497-1501.
    • (1997) Science , vol.277 , pp. 1497-1501
    • Sanchez, Y.1    Wong, C.2    Thoma, R.S.3    Richman, R.4    Wu, Z.5    Piwnica-Worms, H.6    Elledge, S.J.7
  • 78
    • 33644666598 scopus 로고    scopus 로고
    • Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells
    • Xiao, D.; Pinto, J.T.; Gundersen, G.G.; Weinstein, I.B. Effects of a series of organosulfur compounds on mitotic arrest and induction of apoptosis in colon cancer cells. Mol. Cancer Ther., 2005, 4, 1388-1398.
    • (2005) Mol. Cancer Ther , vol.4 , pp. 1388-1398
    • Xiao, D.1    Pinto, J.T.2    Gundersen, G.G.3    Weinstein, I.B.4
  • 79
    • 0026517057 scopus 로고
    • Antiproliferative effect of the garlic compound S-allyl cysteine on human neuroblastoma cells in vitro
    • Welch, C.; Wuarin, L.; Sidell, N. Antiproliferative effect of the garlic compound S-allyl cysteine on human neuroblastoma cells in vitro. Cancer Lett., 1992, 63, 211-219.
    • (1992) Cancer Lett , vol.6 , pp. 211-219
    • Welch, C.1    Wuarin, L.2    Sidell, N.3
  • 80
    • 0033773114 scopus 로고    scopus 로고
    • Apoptosis in cancer: Cause and cure
    • Kaufmann, S.H.; Gores, G.J. Apoptosis in cancer: cause and cure. Bioessays, 2000, 22, 1007-1017.
    • (2000) Bioessays , vol.22 , pp. 1007-1017
    • Kaufmann, S.H.1    Gores, G.J.2
  • 81
  • 82
    • 0034641918 scopus 로고    scopus 로고
    • The biochemistry of apoptosis
    • Hengartner, M.O. The biochemistry of apoptosis. Nature, 2000, 407, 770-776.
    • (2000) Nature , vol.407 , pp. 770-776
    • Hengartner, M.O.1
  • 83
    • 0032575750 scopus 로고    scopus 로고
    • Caspases: Enemies within
    • Thornberry, N.; Lazebnick, Y. Caspases: enemies within. Science, 1998, 281, 1312-1316.
    • (1998) Science , vol.281 , pp. 1312-1316
    • Thornberry, N.1    Lazebnick, Y.2
  • 84
    • 0031918223 scopus 로고    scopus 로고
    • BCL-2 family: Regulators of cell death
    • Chao, D.T.; Korsmeyer, S.J. BCL-2 family: regulators of cell death. Annu. Rev. Immunol., 1998, 16, 395-419.
    • (1998) Annu. Rev. Immunol , vol.16 , pp. 395-419
    • Chao, D.T.1    Korsmeyer, S.J.2
  • 85
    • 0034734611 scopus 로고    scopus 로고
    • Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines
    • Hong, Y.S.; Ham, Y.A.; Choi, J.H.; Kim, J. Effects of allyl sulfur compounds and garlic extract on the expression of Bcl-2, Bax, and p53 in non small cell lung cancer cell lines. Exp. Mol. Med., 2000, 32, 127-134.
    • (2000) Exp. Mol. Med , vol.32 , pp. 127-134
    • Hong, Y.S.1    Ham, Y.A.2    Choi, J.H.3    Kim, J.4
  • 88
    • 3342895063 scopus 로고    scopus 로고
    • Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phos-phorylation of Bcl-2
    • Xiao, D.; Choi, S.; Johnson, D.E.; Vogel, V.G.; Johnson, C.S.; Trump, D.L.; Lee, Y.J.; Singh, S.V. Diallyl trisulfide-induced apoptosis in human prostate cancer cells involves c-Jun N-terminal kinase and extracellular-signal regulated kinase-mediated phos-phorylation of Bcl-2. Oncogene, 2004, 23, 5594-5606.
    • (2004) Oncogene , vol.23 , pp. 5594-5606
    • Xiao, D.1    Choi, S.2    Johnson, D.E.3    Vogel, V.G.4    Johnson, C.S.5    Trump, D.L.6    Lee, Y.J.7    Singh, S.V.8
  • 89
    • 34250721692 scopus 로고    scopus 로고
    • Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak
    • Kim, Y.; Xiao, D.; Xiao, H.; Powolny, A. A.; Lew, K.L.; Reilly, M.L.; Zeng, Y.; Wang, Z.; Singh, S.V. Mitochondria-mediated apoptosis by diallyl trisulfide in human prostate cancer cells is associated with generation of reactive oxygen species and regulated by Bax/Bak. Mol. Cancer Ther., 2007, 6, 1599-1609.
    • (2007) Mol. Cancer Ther , vol.6 , pp. 1599-1609
    • Kim, Y.1    Xiao, D.2    Xiao, H.3    Powolny, A.A.4    Lew, K.L.5    Reilly, M.L.6    Zeng, Y.7    Wang, Z.8    Singh, S.V.9
  • 90
    • 33845299153 scopus 로고    scopus 로고
    • Diallyl trisulfide suppresses growth of PC-3 human prostate cancer xenograft in vivo in association with Bax and Bak induction
    • Xiao, D.; Lew, K. L.; Kim, Y.; Zeng, Y.; Hahm, E.R.; Dhir, R.; Singh, S.V. Diallyl trisulfide suppresses growth of PC-3 human prostate cancer xenograft in vivo in association with Bax and Bak induction. Clin. Cancer Res., 2006, 12, 6836-6843.
    • (2006) Clin. Cancer Res , vol.12 , pp. 6836-6843
    • Xiao, D.1    Lew, K.L.2    Kim, Y.3    Zeng, Y.4    Hahm, E.R.5    Dhir, R.6    Singh, S.V.7
  • 91
    • 33644869135 scopus 로고    scopus 로고
    • Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells
    • Xiao, D.; Singh, S.V. Diallyl trisulfide, a constituent of processed garlic, inactivates Akt to trigger mitochondrial translocation of BAD and caspase-mediated apoptosis in human prostate cancer cells. Carcinogenesis, 2006, 27, 533-540.
    • (2006) Carcinogenesis , vol.27 , pp. 533-540
    • Xiao, D.1    Singh, S.V.2
  • 92
    • 0030071542 scopus 로고    scopus 로고
    • Diallyl disulfide inhibits the proliferation of human tumor cells in culture
    • Sundaram, S.G.; Milner, J.A. Diallyl disulfide inhibits the proliferation of human tumor cells in culture. Biochim. Biophys. Acta., 1996, 1315, 15-20.
    • (1996) Biochim. Biophys. Acta , vol.1315 , pp. 15-20
    • Sundaram, S.G.1    Milner, J.A.2
  • 93
    • 0029970362 scopus 로고    scopus 로고
    • Diallyl disulfide induces apoptosis of human colon tumor cells
    • Sundaram, S.G.; Milner, J.A. Diallyl disulfide induces apoptosis of human colon tumor cells. Carcinogenesis, 1996, 17, 669-673.
    • (1996) Carcinogenesis , vol.17 , pp. 669-673
    • Sundaram, S.G.1    Milner, J.A.2
  • 95
    • 0031445546 scopus 로고    scopus 로고
    • Allyl sulfides from garlic suppress the in vitro proliferation of human A549 lung tumor cells
    • Sakamoto, K.; Lawson, L.D.; Milner, J.A. Allyl sulfides from garlic suppress the in vitro proliferation of human A549 lung tumor cells. Nutr. Cancer, 1997, 29, 152-156.
    • (1997) Nutr. Cancer , vol.29 , pp. 152-156
    • Sakamoto, K.1    Lawson, L.D.2    Milner, J.A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.